Global 19F NMR Database


1	The tabs provide lists of select 19F NMR data for organic, organometallic, and inorganic compounds - sorted by chemical shift.
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7	This data is meant to serve only as a guide to identifying and interpreting signals.
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13	If you would like to contribute data, please send an excel file that is similarly formated to: lly221@lehigh.edu
14	It may take a few days for your data to be added.


1	Compound	Formula	Solvent	Chemical Shift	Splitting Pattern	Coupling Constant in Hz (0 if not observed or m)	Literature Reference or Group data	Notes

2	SF4	F4 S	not reported	97	t	76	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016	axial F; gas phase at -30°C (appears as two broad singlets at RT, as one broad singlet at 85 ∘C)
3	PhSF5	C6 H5 F5 S	CDCl3	84	m		J. Fluorine Chem. 2004, 125, 549-552	axial F; splitting shows a nine-line pattern
4	S=SF2	F2 S2	not reported	77.8	s		Inorg. Chem. 1990, 29, 2698-2701	gas state
5	PhSF5	C6 H5 F5 S	CDCl3	61.9	dm	149.3	J. Fluorine Chem. 2004, 125, 549-552	equatorial F's
6	SF6	F6 S	not reported	54.9	s		Inorg. Chem. 1990, 29, 2698-2701	gas state
7	CH3COF	C2 H3 F O	CH3CN	50	q	7	J. Fluorine Chem. 2000, 106, 217-221
8		C7 H14 Cl F12 N2 P2	CDCl3	47.61	s	0	J. Am. Chem. Soc. 2009, 131, 1662-1663	N-F resonance
9	CH3(CH2)14COF	C16 H31 F O	CDCl3	45.3	s	0	Chem. Eur. J. 2020, 26, 16261-16265
10	PhSC(O)F	C7 H5 F O S	not reported	43.6	s	0	https://pubs.acs.org/doi/abs/10.1021/jo01020a073
11	SF4	F4 S	not reported	37	t	76	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016	equatorial F; gas phase at -30°C (appears as two broad singlets at RT, as one broad singlet at 85 ∘C)
12	4-NO2-PhCOF	C7 H4 F N O3	CDCl3	21.3	s	0	Chem. Eur. J. 2020, 26, 16261-16265
13	PhCOF	C7 H5 F O	CDCl3	17.54	s	0	Org. Lett. 2009, 11, 5050-5053.
14	4-MeO-PhCOF	C8 H7 F O2	CDCl3	15.9	s	0	Chem. Eur. J. 2020, 26, 16261-16265
15	CF3COF	C2 F4 O	not reported	14.9	q	7	Journal of Fluorine Chemistry 1990, 49 (1), 43–66
16	PhSOF	C6 H5 F O S	CD3CN	6.5	s	0	Chem. Ber. 1980, 113, 1047-1052
17	CF2Br2	C Br2 F2		6.28	s	0	Magn. Reson. Chem. 2004; 42: 534–555	6.77 ppm from Ref. 50
18	CF2BrCl	C Br Cl F2		0.01	s	0	Magn. Reson. Chem. 2004; 42: 534–555	Chlorine isotope effect indicates one Cl.
19	CF2Cl2	C Cl2 F2		-6.77	s	0	https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10.1002/mrc.1368
20	(Cy)2NCOF	C13 H22 F N O	CDCl3	-13.1	s	0	Chem. Eur. J. 2019, 25, 10907-10912
21	CF3COF	C2 F4 O		-13.5			https://doi.org/10.1016/S0022-1139(00)82942-5
22	CF3I	C I F3	CDCl3	-15.5	s	0	J. Fluorine Chem. 2008, 129, 131-136
23	(CH3)2NSF3	C2 H6 F3 N S	not reported	-20.2	tsept	J(F(eq), F(ax)) = 58; J(F(eq,CH3) = 8.2	Can. J. Chem. ,1972, 50 (15), 2428-2431	signal for equatorial F
24	CF3Br	C Br F3	not reported	-21	s	0	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016	-17.99; or -18.6 ppm in acetone-d6 at 30 °C, 94.1 MHz, int. CCl3F; or b 21 ppm from Ref. 49, neat, external CCl3F reference.	Ref: Magn. Reson. Chem. 2004; 42: 534–555
25	(PhCH2)2NCOF	C15 H14 F N O	CDCl3	-22.6	s	0	Chem. Eur. J. 2019, 25, 10907-10912
26	COF2 (carbonyl fluoride)	C F2 O	ether	-22.8	s	0	J. Fluorine. Chem. 1989, 43, 235-241
27	CF3Cl	C Cl F3	not reported	-33	s	0	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
28	PF3	F3 P	CDCl3	-33	d	1402.7	Inorg. Chem. 2008, 147, 9279-9292	In gas state, -33ppm	Ref: Inorg. Chem. 1990, 29, 2698-2701
29	PhCHCHCH2SeCF3	C10 H9 F3 Se	CDCl3	-33.8	s	0	ACS Sustainable Chem. Eng. 2018, 6, 1327-1335
30	(C2H5)2NSF3	C4 H10 F3 N S	not reported	-34.4	tquintet	J(Feq,Fax) = 62Hz; J(Feq,NCH) = 6.1 Hz	Can. J. Chem. ,1972, 50 (15), 2428-2431	signal for equatorial F
31	PhCH2SeCF3	C8 H7 F3 Se	CDCl3	-34.5	s	0	ACS Sustainable Chem. Eng. 2018, 6, 1327-1335
32		C9 H6 F3 N Se	CDCl3	-35.9	s	0	Org. Chem. Front., 2019, 6, 2732-2737
33	PhSeCF3	C7 H5 F3 Se	CDCl3	-36.1	s	0	Eur. J. Org. Chem.2017, 530-533
34	CF3S(SO2)CF3	C2 F6 O2 S2	CDCl3	-36.13	q	4.9	Angew.Chem. Int.Ed. 2023, 62,e202306095
35	PhCCSeCF3	C9 H5 F3 Se	CDCl3	-36.2	s	0	Org. Biomol. Chem., 2016, 14, 11502-11509
36	4-MeO-PhSeCF3	C8 H7 F3 O Se	CDCl3	-37.2	s	0	Org. Lett. 2017, 19, 3919-3922
37		C5 H3 F3 S Se	CDCl3	-38.3	s	0	Chem. Eur. J. 2014, 20, 657-661
38	S=CF2	C F2 S	not reported	-40.74	s	0	https://pubs.rsc.org/en/content/articlepdf/1962/jr/jr9620004361
39	CF3SeCl	C Cl F3 Se	THF	-41	s	0	J. Org. Chem. 2016, 81, 8268-8275
40	F2PPh3	C18 H15 F2 P	CDCl3	-42.9	d	659	J. Am. Chem. Soc. 2008, 130, 12214-12215
41	PhCCSCF3	C9 H5 F3 S	CDCl3	-43.6	s	0	Org. Biomol. Chem., 2016, 14, 11502-11509
42	CH3(CH2)5CCSCF3	C9 H13 F3 S	CDCl3	-44.4	s	0	Org. Biomol. Chem., 2016, 14, 11502-11509
43		C6 H11 F3 N2 S	CDCl3	-46.92	s	0	Org. Lett. 2024, 26,6459−6464
44	CF3CO2SCF3	C3 F6 O2 S	not reported	-47.3	s	0, 0	Chem. Ber. 1969, 102, 77-82	SCF3 resonance
45		C8 H4 F3 N O3 S2	CDCl3	-47.3	s	0	Angew. Chem. Int. Ed. 2014, 53, 9316-9320
46		C5 H4 F3 N O2 S	CDCl3	-48.2	s	0	Org. Lett. 2014, 16, 2046-2049
47	[pyridine-F][BF4]	C5 H5 B F5 N	CDCl3	-49	br s	0	J Fluorine Chem. 1991, 53, 369-377	N-F resonance
48	[Ph2SCF3][OTf]	C14 H10 F6 O3 S2	CDCl3	-50.1	s	0	Chem. Eur. J. 2016, 22, 6542-6546	SCF3 resonance
49	PhN(CH3)SCF3	C8 H8 F3 N S	CDCl3	-50.4	s	0	Org. Process. Res. Dev. 2016, 20, 960–964
50	CF3CBr2CF2Cl	C3 Br2 Cl F5		-50.82	q	4J = 11.9 Hz	Magn. Reson. Chem. 2004; 42: 534–555
51	CH3CO2SCF3	C3 H3 F3 O2 S	not reported	-51.9	s	0	J. Fluorine Chem. 1985, 29, 297-310
52	CF3SO2OCF3	C2 F6 O3 S	CDCl3	-53	s	0	Chem. Commun. 2016, 52, 7458-7461	CF3O resonance
53	PhNHSCF3	C7 H6 F3 N S	CDCl3	-53.3	s	0	J. Org. Chem. 2008, 73, 9362-9365
54	(C2H5)2NSF3	C4 H10 F3 N S	not reported	-54	d	62	Can. J. Chem. ,1972, 50 (15), 2428-2431	signal for axial F; couples with equatorial F; dditional fine structure is apparent and an approximate value for the coupling constant of axial F with NCH is 3Hz
55	CH3CH2CH(OCF3)CHCHCO2Et	C9 H13 F3 O3	CDCl3	-58.4	s	0	Chem. Commun. 2016, 52, 7458-7461
56	[Na][BrCF2CO2]	C2 Br F2 Na O2	CDCl3	-58.7	s	0	Vicic Group Data
57	PhCH(OCF3)CO2Et	C11 H11 F3 O3	CDCl3	-59.3	s	0	Chem. Commun. 2016, 52, 7458-7461
58	(CH3)2NSF3	C2 H6 F3 N S	not reported	-59.4	dseptet	J(F(ax), F(eq)) = 58; J(F(ax),CH3) = 5	Can. J. Chem. ,1972, 50 (15), 2428-2431	signal for axial F
59	[Ph2SCH2CF3][OTf]	C15 H12 F6 O3 S2	acetone-d6	-61.3	t	8.8	J. Org. Chem. 2017, 82, 8220-8227	CH2CF3 resonance
60	CF3SO2OCF3	C2 F6 O3 S	CDCl3	-73.6	s	0	Chem. Commun. 2016, 52, 7458-7461	CF3S resonance
61	CF3CO2SCF3	C3 F6 O2 S	not reported	-76.5	s	0, 0	Chem. Ber. 1969, 102, 77-82	CF3-C resonance
62	[PH3PCF2Br]+[Br-]	C19 H15 Br2 F2 P	CDCl3	-52.0	d	83.4	Journal of Fluorine Chemistry 220 (2019) 78–82
63	[PH3PCF2Cl]+[I-]	C19 H15 Cl F2 I P	CDCl3	-52.5	d	87.2	Journal of Fluorine Chemistry 220 (2019) 78–82
64	CF3-CC-CF3	C4 F6	not reported	-53	s	0	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
65	CF3CF2CBr2CF2BrCF2	C5 Br3 F9		-55.81	tt	5J(CF2Br-CF2) = 12.5; 6J(CF2Br-CF3) = 2.6 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Ref. 51 gives -70.36, -104.36, -120.74, and -81.28 ppm, 4Js = 10 and 12 Hz.
66	PhCO2CF3	C8 H5 F3 O2	CDCl3	-57.7	s	0	J. Am. Chem. Soc. 2018, 140, 6801-6805
67	CF3CBrClCClF2	C3 Br Cl2 F5		-58.02	dq	2J(Fa-Fb) = 165.7 Hz; 4J(Fa-CF3) = 11.6 Hz	Magn. Reson. Chem. 2004; 42: 534–555
68	CBrF2CClFCF2Cl	C3 Br Cl2 F5		-58.04	ddd	2J(Fa-Fb) = 173 Hz; 4J(Fa-Fd) = 15.2 Hz; 4J(Fa-Fc) = 13.0 Hz	Magn. Reson. Chem. 2004; 42: 534–555
69	CBrF2CClFCF2Cl	C3 Br Cl2 F5		-58.08	ddd	2J(Fb-Fa) = 173 Hz; 4J(Fb-Fc) = 18.3 Hz; 4J(Fb-Fd) = 12.4 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Overlapping multiplets
70	p-ClC6H4OCF3	C6 H4 Cl F3 O	CDCl3	-58.5	s	0	Angew. Chem. Int. Ed. 2018, 57, 13795-13799
71	CF3CBrClCClF2	C3 Br Cl2 F5		-59.2	dq	2J(Fb-Fa) = 165.7 Hz; 4J(Fb-CF3) = 12.2 Hz	Magn. Reson. Chem. 2004; 42: 534–555
72	[(Me2-N)3C]+[Me3SiF2]-	C10 H27 F2 N Si	MeCN	-59.3	s	0	Inorganic Chemistry. 2002, 41 (23), 6118-6124
73	CBrF2CF2CFCl2	C3 Br Cl2 F5		-59.82	dt	4J(CBrF2-CCl2F) = 14.5 Hz; 3J(CBrF2-CF2) = 1.7 Hz	Magn. Reson. Chem. 2004; 42: 534–555
74	[(o-MeO-C6H4)3PCFBr2]+ [Br]-	C22 H21 Br3 F O3 P	not reported	-60.2	d	99	J. Org. Chem. 1988, 53, 2, 366–374	uncertain; or may also be -63.8,d (J=95)
75	ICF2CO2H	C2 H F2 I O2	CD3CN	-61.1	s	0	Vicic Group Data
76	BrCF2CO2Et	C4 H5 Br F2 O2	CDCl3	-61.7	s	0	Vicic Group Data
77	[Ph3PCFCl2]+[X]-	C19 H16 Cl2 F P X	not reported	-61.8	d	83	J. Org. Chem. 1988, 53, 2, 366–374
78	CF4	C F4	not reported	-62	s	0	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
79	CBrF2CClFCF2Cl	C3 Br Cl2 F5		-62.04	dddd	2J(Fd-Fc) = 170.4 Hz; 4J(Fd-Fa) = 15.2 Hz; 4J(Fd-Fb) = 12.4 Hz; 3J(Fd-Fe) = 7 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Chlorine isotope effect indicates one Cl
80	[PH3PCF2I]+[I-]	C19 H15 F2 I2 P	CDCl3	-62.3	d	82.8	Journal of Fluorine Chemistry 220 (2019) 78–82
81	PhCF3	C7H5F3	CD3CN	-62.5	d	s	New J. Chem., 2017,41, 1417-1420
82	CBrF2CClFCF2Cl	C3 Br Cl2 F5		-62.78	dddd	2J(Fc-Fd) = 170.4 Hz; 4J(Fc-Fb) = 18.3 Hz; 3J(Fc-Fe) = 13.3 Hz; 3J(Fc-Fa) = 13 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Overlapping multiplets
83	[Bu3PCFCl2]+[Cl]-	C13 H27 Cl3 F P	not reported	-62.8	d	68	J. Org. Chem. 1988, 53, 2, 366–374
84	CBrF2CF2CF2Br	C3 Br2 F6		-62.94	t	2.6	Magn. Reson. Chem. 2004; 42: 534–555
85	BrCF2CO2H	C2 H Br F2 O2	CD3CN	-63.2	s	0	Vicic Group Data	-64.5ppm, s, in CDCl3 solvent	Ref: SciFinder; Fluorine-19 NMR Spectrum for 354-08-5; spectrum ID CC-01-F_NMR-17989; (accessed November 4, 2024)
86	CBrF2CF2CF2Cl	C3 Br Cl F6		-63.2	tt	4J(CF2Br-CF2Cl) = 12.8; 3J(CF2Br-CF2) = 2.4 Hz	Magn. Reson. Chem. 2004; 42: 534–555
87	CF3CH2CN	C3 H2 F3 N	CH3CN	-64.3	t	9	J. Fluorine Chem. 2000, 106, 217-221
88		C9 H4 F9 N3 O5 S2	acetone-d6	-64.3, -80.0	s, s	0, 0	Angew. Chem. Int. Ed. 2018, 57, 13784-13789
89	[Ph3PCFClBr]+[X]-	C19 H16 Br Cl F P X	not reported	-65.1	d	80	J. Org. Chem. 1988, 53, 2, 366–374
90	ICF2H	C H F2 I	CDCl3	-66.5	d	56.3	Org. Process Res. Dev. 2020, 24, 1077−1083	-67.9 ppm, d, J = 55 Hz	Ref: (Journal of Fluorine Chemistry 1981, 18 (4), 525–531. https://doi.org/10.1016/S0022-1139(00)82669-X)
91	CBrF2CF2CF2Cl	C3 Br Cl F6		-67.24	tt	4J(CF2Cl-CF2Br) = 12.8; 3J(CF2Cl-CF2) = 1.7 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Decoupling the 116 ppm CF2 collapsed the 67.24 ppm tt to a t with J D 12.8 Hz plus Cl isotope effect suggesting one Cl (from peak heights: 74.6 and 25.4% vs 75.53 and 25.47% natural abundance of Cl isotopes).
92	BrCF2H	C H Br F2	CDCl3	-68.3	d	60	Journal of Fluorine Chemistry 1981, 18 (4), 525–531.
93	CF3CBr2CF2Cl	C3 Br2 Cl F5		-68.65	t	4J = 11.9 Hz	Magn. Reson. Chem. 2004; 42: 534–555
94	Me3Si-CF3	C4 H9 F3 Si	MeCN	-68.74	s	0	Vicic Group data
95	[PH3PCF2SPh]+[I-]	C25 H20 F2 I P S	CDCl3	-69.1	d	92.8	Journal of Fluorine Chemistry 220 (2019) 78–82
96	[PH3PCF2SPhCl]+[Cl-]	C25 H19 Cl2 F2 P S	CDCl3	-70.3	d	91.1	Journal of Fluorine Chemistry 220 (2019) 78–82
97	CF3CBr2CF2CF2CF3	C5 Br2 F10		-70.31	tt	4J(CF3-CF2) = 11 Hz; 5J(CF3-CF2) = 9 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Ref. 51 gives -70.36, -104.36, -120.74, and -81.28 ppm, 4Js = 10 and 12 Hz.
98	[Ph3PCFBr2]+[Br]-	C19 H16 Br3 F P	not reported	-70.4	d	78	J. Org. Chem. 1988, 53, 2, 366–374
99	CF3CBr2CF2CF3	C4 Br2 F8		-70.49	tq	4J(CF3-CF2) = 10.4 Hz; 5J(CF3-CF3) = 6.3 Hz	Magn. Reson. Chem. 2004; 42: 534–555
100	CBrF2CF2CFCl2	C3 Br Cl2 F5		-70.54	tt	4J(CCl2F-CBrF2) = 14.5 Hz; 3J(CCl2F-CF2) = 7.6 Hz	Magn. Reson. Chem. 2004; 42: 534–555
101	Me3Si-(CF(CF3)2)	C6 H9 F7 Si	CDCl3	-70.85	d	11	Tet. Lett. 2001, 42, 3267-3269
102		C24 H26 F3 N2 O4	DMSO -d6	-71.3	d	9.4	Tetrahedron Lett. 2022, 97, 153795
103	CF3CBrClCClF2	C3 Br Cl2 F5		-71.41	dd	4J(CF3-Fb) = 12.2 Hz; 4J(CF3-Fa) = 11.6 Hz	Magn. Reson. Chem. 2004; 42: 534–555
104	[PH3PCF2SePh]+[I-]	C25 H20 F2 I P Se	CDCl3	-71.5	d	89.3	Journal of Fluorine Chemistry 220 (2019) 78–82
105	CF3CBr2CF3	C3 Br2 F6		-72	s		Magn. Reson. Chem. 2004; 42: 534–555
106	CF3CBrClCF2CF3	C4 Br Cl F8		-72.35	ddq	4J(CF3-CF2(a)) = 11.0 Hz; 4J(CF3-CF2(2)) = 10.4 Hz; 5J(CF3-CF3) = 5.6 Hz	Magn. Reson. Chem. 2004; 42: 534–555
107	CF3CF2CBr3	C3 Br3 F5		-73.14	s?		Magn. Reson. Chem. 2004; 42: 534–555
108	CF3CF2CFBrCl	C3 Br Cl F6		-73.39	dqd = m	3J(CFBrCl-CF2(a)-) = 11.5 Hz; 4J(CFBrCl-CF3-) = 10.5 Hz; 3J(CFBrCl-CF2(b)-) = 9.8 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Decoupling the 77.28 ppm CF3 simplified the 73.39 ppm m to a dd with Js 3 9.8 and 11.7 Hz. The Cl isotope effect indicates one Cl (peak heights yield 75 and 25% vs 75.53 and 24.47% natural abundance of Cl isotopes).
109	CF3CF2CBr2Cl	C3 Br2 Cl F5		-73.88	s?		Magn. Reson. Chem. 2004; 42: 534–555	The correct assignment of this component in a mixture as CF3CF2CBr2Cl rather than the isomer CF3CF2CBrCl2 is based on GC–MS (A. C. Sievert).
110	[Bu3PCFBr2]+[Br]-	C13 H27 Br3 F P	not reported	-74.6	d	64	J. Org. Chem. 1988, 53, 2, 366–374
111	CF3COF	C2 F4 O	not reported	-74.9	d	7	Journal of Fluorine Chemistry 1990, 49 (1), 43–66
112	CF3CF2CFBr2	C3 Br2 F6		-75.1	tq	3J(CFBr2-CF2) = 14.0; 4J(CFBr2-CF3) = 10.9 Hz	Magn. Reson. Chem. 2004; 42: 534–555
113	[(o-MeO-C6H4)Ph2PCFBr2]+ [Br]-	C20 H17 Br3 F O P	not reported	-75.3	d	J(F,P) = 70 ; J(H,F) = 40	J. Org. Chem. 1988, 53, 2, 366–374
114	CF3CF2CBr2CF2BrCF2	C5 Br3 F9		-75.21	tt	5J(CF3-CF2) = 7.8; 6J(CF3-CF2Br) = 2.6 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Ref. 51 gives -70.36, -104.36, -120.74, and -81.28 ppm, 4Js = 10 and 12 Hz.
115	[NEt4] [CF3CO2]	C10 H20 F3 O2	CD3CN	-75.8	s	0	Inorg Chem. 2006, 45, 6435-6445
116	[NEt4] [CF3CO2]	C10 H20 F3 O2	CD2Cl2	-75.9	s	0	Inorg Chem. 2006, 45, 6435-6445
117	CF3CBr2CF2CF3	C4 Br2 F8		-76.34	q	5J(CF3-CF3) = 6.3 Hz	Magn. Reson. Chem. 2004; 42: 534–555
118	CF3CF2CFBr2	C3 Br2 F6		-76.64	d	4J(CF3-CFBr2) = 10.9 Hz	Magn. Reson. Chem. 2004; 42: 534–555
119	CF3S(SO2)CF3	C2 F6 O2 S2	CDCl3	-76.8	q	4.9	Angew.Chem. Int.Ed. 2023, 62,e202306095
120	Me3SiOCH(NMe2)CF3	C6 H16 F3 N Si	CDCl3	-77.2	d	5.8	J. Fluorine Chem. 2001, 112, 283-286	TMS-CF3 adduct of DMF
121	CF3CF2CFBrCl	C3 Br Cl F6		-77.28	d	4J(CF3-CFBrCl) = 10.5 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Decoupling the 73.39 ppm CF resulted in the collapse of the 77.28 ppm d to an s.
122		C15 H10 F3 I O3 S	DMSO-d6	-77.6	s	0	J. Am. Chem. Soc. 2013, 135, 8782-8785
123	CF3CH2OH	C2 H3 F3 O	not reported	-78	t	8.8	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
124	CF3SO2OH	C H F3 O3 S	D2O	-78.42	s	0	Dalton Trans., 2013, 42, 4299–4305
125		C10 H15 F6 N3 O4 S2	D2O	-78.78	s	0	Dalton Trans., 2013, 42, 4299–4305
126	[NBu4] [CF3SO3]	C17 H36 F3 N O3 S	CD2Cl4	-78.8	s	0	Org. Lett. 2008, 10, 4867-4870
127	CHF3	C H F3	CD3CN	-78.9	d	79.3	J. Fluorine Chem. 2000, 106, 217-221
128	CF3SO2NH2	C H2 F3 N O2 S	D2O	-79.34	s	0	Dalton Trans., 2013, 42, 4299–4305
129	CHCl2F	C H Cl2 F	not reported	-80.3	d	54	J. Org. Chem. 1988, 53, 2, 366–374
130	Me3Si-CF2CF2CF3	C6 H9 F7 Si	CDCl3	-80.8	s	0	J. Org. Chem. 1991, 56, 984-989
131		C8 H8 F2 O	CDCl3	-80.9	d	74.7	Org. Lett. 2021, 13, 5568-5571
132	CF2=CH2	C2 H2 F2	not reported	-81	dd	3J(F-H) = 34; 3J(F-H) = 1 Hz	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
133	CF3CBr2CF2CF2CF3	C5 Br2 F10		-81.32	t	4J(CF3-CCF2) = 12.35 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Ref. 51 gives -70.36, -104.36, -120.74, and -81.28 ppm, 4Js = 10 and 12 Hz.
134	Me3Si-CF2CF3	C5 H9 F5 Si	n-hexane	-82.4	s	0	Ang. Chem. Int. Ed. 2019, 58, 14633-14638	C-F and Si-F coupling constants reported
135	CHBr2Cl	C H Br2 Cl	not reported	-83.9	d	51	J. Org. Chem. 1988, 53, 2, 366–374
136	CF3SOOH	C H F3 O2 S	D2O	-87.07	s	0	Dalton Trans., 2013, 42, 4299–4305
137	C2F6	C2 F6	THF-d8	-87.74	s	0	Vicic Group data
138	CH3CF2CN	C3 H3 F2 N	not reported	-85	q	18.1	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
139	C2F6	C2 F6	DMF-d7	-88.07	s	0	Vicic Group data
140	CH3-O-CF2CF3	C3 H3 F5 O	CDCl3	-87.2	s	0	Inorganic Chemistry. 2002, 41 (23), 6118-6124
141	CH3-O-CF2CF3	C3 H3 F5 O	CDCl3	-87.6	s	0	Inorganic Chemistry. 2002, 41 (23), 6118-6124
142	Ph-(CH2)5-O-CF2CF3	C13 H15 F5 O	CDCl3	-86.2	s	0	J. Org. Chem. 2017, 82, 3702-3709.
143	4-NO2-PhSeCF2H	C7 H5 F2 N O2 Se	CDCl3	-89.8	d	54.6	Tetrahedron, 2018, 74, 5642-5649
144	PhSeCF2H	C7 H6 F2 Se	CDCl3	-90.3	d	55	Tetrahedron, 2018, 74, 5642-5649
145	Ph-(CH2)5-O-CF2CF3	C13 H15 F5 O	CDCl3	-90.7	s	0	J. Org. Chem. 2017, 82, 3702-3709.
146	4-MeO-PhSeCF2H	C8 H8 F2 O Se	CDCl3	-91.1	d	55.6	Tetrahedron, 2018, 74, 5642-5649
147	CF3CF2CBr2CF2BrCF2	C5 Br3 F9		-95.78	qt	5J(CF2-CF3) = 7.8; 4J(CF2-CF2) = 10 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Ref. 51 gives -70.36, -104.36, -120.74, and -81.28 ppm, 4Js = 10 and 12 Hz.
148		C16 H17 F8 O3 P S	CDCl3	-97.0, -98.0	dd, dd	233.5, 53.9 and 233.5, 53.9	Chem. Commun., 2019, 55, 7446-7449	CF2H resonances
149	(S)-2-amino-4-fluoro-pent-4-enoic acid	C5 H9 F N O2	D2O	-98.4	ddt	18.0, 22.3, 50.8	Asian. J. Org. Chem. 2014, 3, 1270-1272	Fluorinated Asparagine Derivative
150	CF2=CHF	C2 H1 F3	not reported	-100	ddd	2J(F-F) = 87; 3J(F-F) = 33; 3J(F,H) = 13 Hz	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016	F trans to H
151	CF3CBr2CF2CF2CF3	C5 Br2 F10		-104.06	qqt	4J(CF2-CF3) = 12.35 Hz; 4J(CF2-CBr2CF3) = 11 Hz; 3J(CF2-CF2)	Magn. Reson. Chem. 2004; 42: 534–555	Ref. 51 gives -70.36, -104.36, -120.74, and -81.28 ppm, 4Js = 10 and 12 Hz.
152	CF3CF2CBr2CF2BrCF2	C5 Br3 F9		-106.11	tt	5J(CF2-CF3) = 7.8; 6J(CF2-CF2Br) = 10 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Ref. 51 gives -70.36, -104.36, -120.74, and -81.28 ppm, 4Js = 10 and 12 Hz.
153	CF3CBr2CF2CF3	C4 Br2 F8		-107.32	q	4J(CF2-CF3) = 10.4 Hz	Magn. Reson. Chem. 2004; 42: 534–555
154	CF3CF2CBr3	C3 Br3 F5		-107.5	s?		Magn. Reson. Chem. 2004; 42: 534–555
155	PhC(F)CH2	C8 H7 F	CDCl3	-108.4	dd	49.3, 17.7	J. Org. Chem. 2009, 74, 8377-8380
156		C13 H8 F2 O	CDCl3	-108.74	d	56.5	J. Am. Chem. Soc. 2016, 138, 2536-2539.
157	CF3CF2CBr2Cl	C3 Br2 Cl F5		-109.37	s?		Magn. Reson. Chem. 2004; 42: 534–555	The correct assignment of this component in a mixture as CF3CF2CBr2Cl rather than the isomer CF3CF2CBrCl2 is based on GC–MS (A. C. Sievert).
158	CBrF2CF2CFCl2	C3 Br Cl2 F5		-110.4	dt	3J(CF2-CCl2F) = 7.6 Hz; 3J(CF2-CBrF2) = 1.7 Hz	Magn. Reson. Chem. 2004; 42: 534–555
159	CF3CBrClCF2CF3	C4 Br Cl F8		-110.41	dq	2J(CF2(a)-CF2(b)) = 273.4 Hz; 4J(CF2(a)-CF3) = 11.0 Hz	Magn. Reson. Chem. 2004; 42: 534–555
160	CF3CBrClCF2CF3	C4 Br Cl F8		-110.75	dq	2J(CF2(b)-CF2(a)) = 273.4 Hz; 4J(CF2(b)-CF3) = 10.4 Hz	Magn. Reson. Chem. 2004; 42: 534–555
161		C13 H10 F2	CDCl3	-111.47	d	56.1	J. Am. Chem. Soc. 2016, 138, 2536-2539.
162		C11 H8 F2	CDCl3	-111.66	d	56.4	J. Am. Chem. Soc. 2016, 138, 2536-2539.
163		C14 H10 F2 O	CDCl3	-112.9	d	55.9	J. Am. Chem. Soc. 2016, 138, 2536-2539.
164		C6 H5 F2 N	CDCl3	-113	d	55.4	Nat. Commun. 2018, 9 (1), 1170.
165	CHF=CH2	C2 H3 F	not reported	-113	ddd	2J(F-H) = 85; 3J(F-H) = 52; 3J(F-H) = 20 Hz	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
166		C9 H8 F2 O	CDCl3	-113.15	d	56.1	J. Am. Chem. Soc. 2016, 138, 2536-2539.
167		C10 H10 F2 O2	CDCl3	-113.31	d	56.3	J. Am. Chem. Soc. 2016, 138, 2536-2539.
168		C9 H8 F2 O2	CDCl3	-113.41	d	56.9	J. Am. Chem. Soc. 2016, 138, 2536-2539.
169	CBrF2CF2CF2Br	C3 Br2 F6		-113.15	t	2.6	Magn. Reson. Chem. 2004; 42: 534–555
170		C8 H6 F2 O	CDCl3	-114.03	d	56.2	J. Am. Chem. Soc. 2016, 138, 2536-2539.
171		C9 H8 F2 O	CDCl3	-114.03	d	56.1	J. Am. Chem. Soc. 2016, 138, 2536-2539.
172	[Ph2SCH2CF2H][OTf]	C15 H13 F5 O3 S2	CDCl3	-114.2	dt	53.8, 15.0	Chem. Commun., 2016, 52, 11893-11896	CF2H resonance
173	CF3CF2CFBr2	C3 Br2 F6		-115.31	d	3J(CF2-CFBr2) = 14.0 Hz	Magn. Reson. Chem. 2004; 42: 534–555
174	Ph-F	C6 H5 F	C6D6	-115.9	m	0	Chem. Commun. 2010, 46, 5151-5153
175	CBrF2CF2CF2Cl	C3 Br Cl F6		-116	tt	3J(CF2-CF2Br) = 2.4; 3J(CF2-CF2Cl) = 1.7 Hz	Magn. Reson. Chem. 2004; 42: 534–555
176	CF3CF2CFBrCl	C3 Br Cl F6		-116.28	dd	2J(CF2(a)-CF2(b) = 271.1 Hz; 3J(CF2(a)-CFBrCl) = 11.5 Hz	Magn. Reson. Chem. 2004; 42: 534–555
177	CF3CF2CFBrCl	C3 Br Cl F6		-117.9	dd	2J(CF2(b)-CF2(a) = 271.1 Hz; 3J(CF2(b)-CFBrCl) = 9.8 Hz	Magn. Reson. Chem. 2004; 42: 534–555
178		C6 H4 F2 O2	CDCl3	-118.71	d	53.8	J. Am. Chem. Soc. 2016, 138, 2536-2539.
179	CH3CH2CF2H	C3 H6 F2	not reported	-120	dt	57, 17.5	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
180	CF3CBr2CF2CF2CF3	C5 Br2 F10		-120.39	qt	5J(CF2-CCCF3) = 9 Hz; 3J(CF2-CF2) = 5.5 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Ref. 51 gives -70.36, -104.36, -120.74, and -81.28 ppm, 4Js = 10 and 12 Hz.
181	1,1,2-Trifluoroethane	C2 H3 F3	not reported	-121, -239		46, 18, 14, 7, 3.5	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
182	Me3Si-CF2CF2CF3	C6 H9 F7 Si	CDCl3	-124.1	s	0	J. Org. Chem. 1991, 56, 984-989
183	CBrF2CClFCF2Cl	C3 Br Cl2 F5		-124.6	dd	3J(Fe-Fc) = 13.3 Hz; 3J(Fe-Fd) = 7 Hz	Magn. Reson. Chem. 2004; 42: 534–555	Decoupling the 124.60 ppm F resulted in the collapse of the -58 ppm overlapping multiplets to two dd centered at 58.04 ppm (Js D 15.2 and 13.0 Hz) and at 58.08 ppm (Js D 18.3 and 12.4 Hz). The upfield part of the 62 ppm resonance showed a chlorine isotope effect indicating one Cl.
184	CF2=CHF	C2 H1 F3	not reported	-126	ddd	3J(F-F) = 119; 2J(F-F) = 87; 3J(F,H) = 4 Hz	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016	F cis to H
185	CF2HCOOH	C2 H2 F2 O2		-126.18	d	53.1	Magn. Reson. Chem. 2004; 42: 534–555
186	[Ph3P-F]+	C18 H15 F	CD2Cl2	-128.1	d	997	Chem. Sci. 2015, 6, 2016-2021
187	SFFS	F2 S2	not reported	-128.8	s		Inorg. Chem. 1990, 29, 2698-2701	gas state
188	Me3Si-CF2CF2CF3	C6 H9 F7 Si	CDCl3	-129.7	s	0	J. Org. Chem. 1991, 56, 984-989
189	Me3Si-CF2CF3	C5 H9 F5 Si	n-hexane	-131.9	s	0	Ang. Chem. Int. Ed. 2019, 58, 14633-14638	C-F and Si-F coupling constants reported
190	CF2=CF2	C2 F4	acetone-d6	-133.8	s	0	Can. J. Chem. 2004, 82, 1186-1191
191	perfluorocyclobutane	C4 F8	CDCl3	-134	s	0	J. Fluorine Chem. 2016, 127, 79-84.
192	perfluorocyclobutane	C4 F8	acetone-d6	-135.5	s	0	Can. J. Chem. 2004, 82, 1186-1191
193	1,1,2,2-tetrafluoroethane	C2 H2 F4		-137.3	dd	2J(F,H) = 52; 3J(F,H) = 5	Magn. Reson. Chem. 2004, 42 (6), 534–555.
194	SiF4	F4 Si	not reported	-142	s		Inorg. Chem. 1990, 29, 2698-2701
195	[t-Bu3PCFHCl]+[Cl]-	C13 H28 Cl2 F P	not reported	-146.7	dd	J(F,P) = 48 ; J(H,F) = 37	J. Org. Chem. 1988, 53, 2, 366–374
196	CH2F2	C H2 F2	not reported	-148	t	50	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
197	[Bu3PCFPBu3]+[BF4]-	C25 H54 B F5 P2	not reported	-150.1	s		J. Org. Chem. 1988, 53, 2, 366–374
198	[Ph3PCFPPh3]+[BF4]-	C37 H30 B F5 P2	not reported	-150.1	s		J. Org. Chem. 1988, 53, 2, 366–374
199	[(o-MeO-C6H4)3PCFHBr]+ [Br]-	C22 H22 Br2 F O3 P	not reported	-151.0	dd	J(F,P) = 84 ; J(H,F) = 44	J. Org. Chem. 1988, 53, 2, 366–374
200	[NBu4][HF2]	C16 H37 F2 N	CD2Cl2	-151.5	d	123	J. Fluorine. Chem. 2006, 127, 920-923
201	[i-Pr3PCFHCl]+[Cl]-	C10 H22 Cl2 F P	not reported	-154.2	dd	J(F,P) = 51 ; J(H,F) = 40	J. Org. Chem. 1988, 53, 2, 366–374
202	(CH3)3SiF	C3 H9 F Si	not reported	-155	s		Inorg. Chem. 1990, 29, 2698-2701
203	perfluorocyclopropane	C3 F6	CH3CN	-156.5	s		J. Fluorine Chem. 2000, 106, 217-221
204	[Et3PCFHCl]+[Cl]-	C7 H16 Cl2 F P	not reported	-156.7	dd	J(F,P) = 55 ; J(H,F) = 44	J. Org. Chem. 1988, 53, 2, 366–374
205	cyclobutyl fluoride	C4 H7 F	CDCl3	-160	dm	55	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
206	Me3Si-F	C3 F9 F Si	CDCl3	-160.5	decet	7.3	Inorg. Chem. 1988, 27, 2913-2916
207	[(o-MeO-C6H4)Ph2PCFHBr]+ [Br]-	C20 H18 Br2 F O P	not reported	-161.1	dd	J(F,P) = 70 ; J(H,F) = 40	J. Org. Chem. 1988, 53, 2, 366–374
208	hexafluorobenzene	C6 F6	not reported	-162	s	0	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
209	[Bu3PCFHBr]+[Br]-	C13 H28 Br2 F P	not reported	-162.7	dd	J(F,P) = 56 ; J(H,F) = 44	J. Org. Chem. 1988, 53, 2, 366–374
210	[Ph3PCFHBr]+[Br]-	C19 H16 Br2 F P	not reported	-163.9	dd	J(F,P) = 70 ; J(H,F) = 40	J. Org. Chem. 1988, 53, 2, 366–374
211	CHF=CHF (cis isomer)	C2 H2 F2	not reported	-165	ddd	2J(F-H) = 73; 3J(F-H) = 20; 3J(F-F) = 19 Hz	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
212	SF2	F2 S	not reported	-167	s		Inorg. Chem. 1990, 29, 2698-2701	gas state
213	CH2=CHCFHCH3	C4 H7 F	not reported	-170	dm	48	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
214	2-fluoropentane	C5 H11 F	CD2Cl2	-172.8	m	0	J. Org. Chem. 1980, 45, 3476-3483
215	3-fluoropentane	C5 H11 F	CD2Cl2	-182.7	m	0	J. Org. Chem. 1980, 45, 3476-3483
216	CHF=CHF (trans isomer)	C2 H2 F2		-186	ddd	3J(F,F) = 125 ; 2J(F,H) = 74; 3J(F,H) = 4 Hz	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
217	(CH3)2PF	C2 F7 P	not reported	-196	s		Inorg. Chem. 1990, 29, 2698-2701
218	CF2=CHF	C2 H1 F3	not reported	-205	ddd	3J(F-F) = 119; 2J(F-H) = 71; 3J(F,F) = 33 Hz	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
219	Me3Si-(CF(CF3)2)	C6 H9 F7 Si	CDCl3	-208.11	m	0	Tet. Lett. 2001, 42, 3267-3269
220	[Ph3PCFHPPh3]2+ 2[Br]-	C37 H31 Br2 F P2	not reported	-210.6	td	J(F,P) = 59 ; J(H,F) = 40	J. Org. Chem. 1988, 53, 2, 366–374
221	CH3-CH2F	C2 H5 F	CD2Cl2	-211.5	td	48.5, 25	J. Org. Chem. 1980, 45, 3476-3483
222	Fluoroethane	C2 H5 F	not reported	-212		48.5, 27	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016	pg 77
223	cyclopropyl fluoride	C3 H5 F	not reported	-213	ddd	65, 22, 10	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
224	[Ph3PCFHPBu3]2+ 2[Br]-	C31 H43 Br2 F P2	not reported	-215	ddd	J(F,PPh3) = 59 ; J(F,PBu3) = 50; J(H, F) = 39	J. Org. Chem. 1988, 53, 2, 366–374
225	[Ph3PCFHPEt3]2+ 2[Br]-	C25 H32 Br2 F P2	not reported	-215.2	ddd	J(F,PPh3) = 59 ; J(F,PEt3) = 49; J(H, F) = 39	J. Org. Chem. 1988, 53, 2, 366–374
226	[Ph3PCFHPOc3]2+ 2[Br]-	C43 H67 Br2 F P2	not reported	-215.4	ddd	J(F,PPh3) = 59 ; J(F,POc3) = 49; J(H, F) = 37	J. Org. Chem. 1988, 53, 2, 366–374
227	(CF3)2PF	C2 F7 P	not reported	-218	s		Inorg. Chem. 1990, 29, 2698-2701
228	[Bu3PCFHPBu3]2+ 2[Cl]-	C25 H55 Cl2 F P2	not reported	-221.6	td	J(F,P) = 51 ; J(H,F) = 42	J. Org. Chem. 1988, 53, 2, 366–374
229	[Bu3PCFHPBu3]2+ 2[Br]-	C25 H55 Br2 F P2	not reported	-222.4	td	J(F,P) = 50 ; J(H,F) = 42	J. Org. Chem. 1988, 53, 2, 366–374
230	1,2-Difluoroethane	C2 H4 F2	not reported	-226		45, 17	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016	pg 77
231	[Ph3PCFH2]+[Br]-	C19 H17 Br F P	not reported	-244.3	dt	J(F,P) = 56 ; J(H,F) = 44	J. Org. Chem. 1988, 53, 2, 366–374
232	[t-Bu3PCFH2]+[Cl]-	C13 H29 Cl F P	not reported	-247.4	dd	J(F,P) = 45 ; J(H,F) = 35	J. Org. Chem. 1988, 53, 2, 366–374
233	[Bu3PCFH2]+[Cl]-	C13 H29 Cl F P	not reported	-250.1	dt	J(F,P) = 53 ; J(H,F) = 44	J. Org. Chem. 1988, 53, 2, 366–374
234	[i-Pr3PCFH2]+[Cl]-	C10 H23 Cl F P	not reported	-252	dt	J(F,P) = 44 ; J(H,F) = 44	J. Org. Chem. 1988, 53, 2, 366–374
235	[Ph3PCFPPh3]+[BF4]-	C37 H30 B F5 P2	not reported	-262.1	t	49	J. Org. Chem. 1988, 53, 2, 366–374
236	[Ph3PCFPPh3]+[Br]-	C37 H30 Br F P2	not reported	-262.8	t	49	J. Org. Chem. 1988, 53, 2, 366–374
237	CH3F	C H3 F	CH2Cl2	-268	q	46	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
238	[Ph3PCFPBu3]+[Br]-	C31 H42 Br F P2	not reported	-268.4	dd	J(F,PBu3) = 39 ; J(F,PPh3) = 49	J. Org. Chem. 1988, 53, 2, 366–374
239	[Ph3PCFPOc3]+[Br]-	C43 H66 Br F P2	not reported	-269.0	dd	J(F,POc3) = 41 ; J(F,PPh3) = 47	J. Org. Chem. 1988, 53, 2, 366–374
240	[Ph3PCFPEt3]+[Br]-	C25 H30 Br F P2	not reported	-271.4	dd	J(F,PEt3) = 39 ; J(F,PPh3) = 49	J. Org. Chem. 1988, 53, 2, 366–374
241	[Bu3PCFPBu3]+[Br]-	C25 H54 Br F P2	not reported	-283.8	t	42	J. Org. Chem. 1988, 53, 2, 366–374
242	[Bu3PCFPBu3]+[BF4]-	C25 H54 B F5 P2	not reported	-284.5	t	42	J. Org. Chem. 1988, 53, 2, 366–374
243	[Bu3PCFPBu3]+[Cl]-	C25 H54 Cl F P2	not reported	-285	t	42	J. Org. Chem. 1988, 53, 2, 366–374
244	[Et3PCFPEt3]+[Cl]-	C13 H30 Cl F P2	not reported	-288.8	t	41	J. Org. Chem. 1988, 53, 2, 366–374
245	CF3SF	C F4 S	not reported	-351	s		Inorg. Chem. 1990, 29, 2698-2701


1	Compound	Formula	Solvent	Chemical Shift (vs CFCl3 = 0)	Splitting Pattern	Coupling Constant in Hz (0 if not observed or m)	Literature Reference or Group data	Notes

2	Alanine derivatives
3	Fmoc-beta- fluoroalanine	C18 H15 F2 N O4	CD3OD	-126.15	ddd	279.7, 56.8, 7.1	Org. Lett. 2007, 9, 41–44	Fluorinated Alanine Derivative
4	Cbz-(2R)-3-flluoroalanine	C11 H12 F1 N1 O4	CDCl3	-229.7 to -231.3	m	0	Org. Lett. 2006, 8(25), 5849-5852	Fluorinated Alanine Derivative
5	Cbz-(2S)-3-flluoroalanine	C11 H12 F1 N1 O4	CDCl3	-229.8 to -231.3	m	0	Org. Lett. 2006, 8(25), 5849-5852	Fluorinated Alanine Derivative
6
7	Aspartic acid derivatives
8	(2S, 3 R) 3-fluoro-D-aspartic acid		D2O+ DCl	-196.6	dd	29, 44	https://doi.org/10.1016/0040-4039(96)01044-1	Fluorinated Aspartic Acid Derivative
9	(2S, 3 S) 3-fluoro-D-aspartic acid		D2O+ DCl	-198.5	dd	29, 48	https://doi.org/10.1016/0040-4039(96)01044-1	Fluorinated Aspartic Acid Derivative
10
11	Arginine derivatives
12	4,4- Difluoro-L-Arginine Acetate	C6 H13 F2 N4 O2	D2O	-102.7 to -105.1	m	0	Bioorg. Med. Chem. Lett. 2009. 19, 1758–1762	Fluorinated Arginine Derivative
13
14	Cysteine derivatives
15	S-CF3-L-Cysteine		D2O	-41.4	s	0	https://www.sciencedirect.com/science/article/pii/S0022113911000030?casa_token=3Yjc3gWA0ZUAAAAA:B7nQ-RTfS6eWlLybnZt3e5wNSqRKzLE_J9P7NI5YSmYFsX02CPuGE8eoFtU5fDmCkOAXX3aBlnw	Fluorinated Cysteine Derivative
16
17	Glutamine derivatives
18	Erythro- 4-fluoroglutamine	C5 H9 F N2 O3	D2O	−186.4	ddd	48.9, 37.6, 15.6	Journal of Fluorine Chemistry, 2000, 1,5-10
19	Threo-4-fluoroglutamine	C5 H9 F N2 O3	D2O	−186.3	ddd	48.8, 30.3, 22.9	Journal of Fluorine Chemistry, 2000, 1,5-10
20	dl-4,4-Difluoroglutamine	C5 H8 F2 N2 O3	D2O	−30.6, −28.9,	ddd, ddd	12.7, 24.9, 256 9.9, 25.9, 256	J. Org. Chem. 1996, 61, 7, 2497–2500
21
22
23	Glutamic acid derivatives
24	3-fluoroglutamic acids	C5 H8 F N O4	H2O, C2F3O2-	-154	12		J. Org. Chem. 1985, 50, 17, 3163–3167
25	4-fluoro-l-glutamic acid	C5 H8 F N O4
26	(2S)-4,4-Difluoroglutamic Acid	C5 H7 F2 N O4	D2O	−103.36, −104.45	ddd, ddd	2JFF = 251.8 Hz, 3JHF = 21.3, 12.8, 2JFF = 251.8 Hz, 3JHF = 19.2, 14.9	J. Org. Chem. 2001, 66, 19, 6381–6388
27
28	Glycine derivatives
29
30
31	Histidine derivatives
32	2-Fluoro-L-histidine	C6 H8 F N3 O2	H2O	59.8			https://www.nature.com/articles/srep42651#MOESM40
33	4-fluorohistidine	C6 H8 F N3 O2	H2O	-68.31			https://www.nature.com/articles/srep42651#MOESM40
34	4-(Trifluoromethyl)phenyl-histidine
35
36	Isoleucine derivatives
37	(2S,3S)-3'-fluoroisoleucine						https://pubs.rsc.org/en/content/articlelanding/2004/OB/B316219B
38	4-fluoroisoleucine						https://pubs.rsc.org/en/content/articlelanding/2004/OB/B316219B
39	4′,4′,4′-trifluoroisoleucine						https://pubs.rsc.org/en/content/articlelanding/2012/OB/c2ob26810h
40	5,5,5-trifluoroisoleucine						https://www.beilstein-journals.org/bjoc/articles/9/236
41
42
43
44
45	Leucine derivatives
46	(S)-2-Amino-5-fluoro-4(fluoromethyl) pentanoic acid hydrochloride	C6 H12 Cl F2 O2	CD3OD	-230.36, -230.50	td	46.8, 20.5 and 46.3, 21.8	Org. Biomol. Chem., 2022,20, 2424-2432
47	(S)-2(tert-butyloxycarbonyl)amino-4,5-difluoro-4(fluoromethyl)pentanoic acid	C11 H17 F3 N1 O4	CD3OD	-174.11, -236.16, -236.95	-174.11(m), -236.16(td), -236.95(td)	-236.16(td, 47.1, 12.4), -236.95(td, 47.0, 12.2)	Org. Biomol. Chem., 2022,20, 2424-2432
48	(2S,4S)-5,5,5-Trifluoroleucine						https://pubs.acs.org/doi/10.1021/jo900654y
49
50
51	Lysine derivatives
52	(5S)-N6-(iminoethyl)-5-fluoro-L-lysine hydrochloride	C8 H15 F1 N3 O2	D2O, CFCl3	-187.5			J. Med. Chem. 2004, 47, 4, 900–906
53	N6-(iminoethyl)-4,4-difluoro-L-lysine dihydrochloride	C8 H15 F2 N3 O2	D2O	-98.2			Org. Biomol. Chem., 2003,1, 3527-3534
54
55	Methionine derivatives
56	L-Trifluoromethionine	C5 H8 F3 N1 O2 S1	D2O	-41.3	s		J. of Fluorine Chem., 2011, 132, 3, 186-189
57	L-pentafluoroethionine	C5 H8 F5 N1 O2 S1	D2O	-93.8, -85.3	s,s		Patent US20110015433
58	N-Boc-L-trifluoromethionine	C10 H16 F3 N1 O4 S1	CDCl3	-42	s		Patent US20110015433
59
60	Phenylalanine derivatives
61	2-Amino-3,3-difluoro-3-(4-fluorophenyl)propionic acid	C9 H9 F2 N1 O2	CD3OD	-90.4, -109.3	dd	250.3, 4.8 and 250.3, 21.1	Tetrahedron, 2004, 60, 35, 7731-7742
62	(2R,3S)-2-Amino-3-fluoro-3-phenylpropanoic acid [(2R,3S)-β-fluorophenylanaline]	C9 H10 F1 N1 O2	MeOH-d4	-188.3			Org. Lett. 2015, 17, 9, 2254–2257
63
64	Proline derivatives
65	Methyl (2S,4S)-N-acetyl-4-trifluoromethylprolinate	C9 H12 F3 N1 O3	D2O	-71.0 (major), -71.3 (minor)	d	9, 10	Org. Biomol. Chem., 2015,13, 3171-3181
66	Methyl (2S,4S)-N-acetyl-4-trifluoromethylprolinate	C9 H12 F3 N2 O3	DMSO-d6	-69.4 (major), -69.9 (minor)	d	9, 11	Org. Biomol. Chem., 2015,13, 3171-3181
67	Ethyl trans-3-(perfluoroethyl)pyrrolidine-2-carboxylate hydrochloride	C9 H13 Cl1 F5 N1 O2	CD3OD	-84.51 (s), -118.38 (dd), -124.13 (dd)	s, dd, dd	-84.51 (s, CF3), -118.38 (dd, 273.0, 13.1, FA of CF2), -124.13 (dd, 273.0, 19.2, FB of CF2)	Chem. Commun., 2018,54, 9683-9686
68	trans-3-(Difluoromethyl)-3-hydroxypyrrolidine-2-carboxylic acid hydrochloride	C6 H10 Cl1 F2 N1 O3	CD3OD	-129.05, -132.61	dd	290, 54.4 and 290, 54.5	Chem. Commun., 2018,54, 9683-9686
69
70	Serine derivatives
71	N-(11-F-hexyl)-undecanoyl)-(L)-serine hexadecylamide	C36 H59 F13 N2 O3					Tetrahedron. 1995, 51, 13073-13088
72	N-(11-(F-butyl)-undecanoyl)-L-serine11-(F-butyl)-undecylamide	C33 H48 F13 N2 O3	CDCl3	-81.6 (3F, CF3)			Tetrahedron. 1995, 51, 13073-13088
73				-115.1 (2F, CF2CH2)
74				-125.0 (2F, CF2CF2CH2)
75				-126.6 (2F, CF3CF2)
76	N-(11-(F-hexyl)-undecanoyl)-L-serine11-(F-butyl)-undecylamide	C35 H48 F22 N2 O3	CDCl3/CDOD	-81.4, -81.6 (3F, 3F, CF3)			Tetrahedron. 1995, 51, 13073-13088
77				-115.0 (4F, CF2CH2)
78				-122.5, -123.4, -124.1, 125.0 (2F, 2F, 2F, 2F (CF2)3F2CH2)
79				-126.6 (4F, CF3CF2).
80	N-(11-(F-hexyl)-undecanoyl)-L-serine11-(F-hexyl)-undecylamide	C37 H48 F26 N2 O3	CDCl3/CDOD	-81.3 (3F, CF3)			Tetrahedron. 1995, 51, 13073-13088
81				-114.9 (2F, CF2CH2)
82				122.4, -123.4, -124.1 (2F, 2F, 2F, (CF2)3CF2CH2)
83				-126.6 (2F, CF3CF2)
84	8a (see Tetrahedron. 1995, 51, 13073-13088)	C43 H65 F13 N2 O3	CDCl3	-81.3 (3F, CF3)			Tetrahedron. 1995, 51, 13073-13088
85				-114.9 (2F, CF2CH2)
86				122.4, -123.4, -124.1 (2F, 2F, 2F, (CF2)3CF2CH2)
87				-126.6 (2F, CF3CF2)
88	8b (see Tetrahedron. 1995, 51, 13073-13088)	C40 H54 F18 N2 O3	CDCl3	-81.6 (3F, CF3)			Tetrahedron. 1995, 51, 13073-13088
89				-115.1 (2F, CF2CH2)
90				-125.0 (2F, CF2CF2CH2)
91				-126.6 (2F, CF3CF2)
92	8c (see Tetrahedron. 1995, 51, 13073-13088)	C42 H54 F22 N2 O3	CDCl3	-81.4, -81.6 (3F, 3F, CF3)			Tetrahedron. 1995, 51, 13073-13088
93				-115.0 (4F, CF2CH2)
94				-122.5, -123.4, -124.1, 125.0 (2F, 2F, 2F, 2F (CF2)3F2CH2)
95				-126.6 (4F, CF3CF2).
96	7b (see Tetrahedron. 1995, 51, 13073-13088)	C25 H35 F9 N2 O2	CDCl3	-81.6 (3F, CF3)			Tetrahedron. 1995, 51, 13073-13088
97				-115.1 (2F, CF2CH2)
98				-125.0 (2F, CF2CF2CH2)
99				-126.6 (2F, CF3CF2)
100	7c (see Tetrahedron. 1995, 51, 13073-13088)	C27 H35 F13 N2 O2	CDCl3	-81.3 (3F, CF3)			Tetrahedron. 1995, 51, 13073-13088
101				-114.9 (2F, CF2CH2)
102				122.4, -123.4, -124.1 (2F, 2F, 2F, (CF2)3CF2CH2)
103				-126.6 (2F, CF3CF2)
104	6b (see Tetrahedron. 1995, 51, 13073-13088)	C30 H43 F9 N2 O4	CDCl3	-81.6 (3F, CF3)			Tetrahedron. 1995, 51, 13073-13088
105				-115.1 (2F, CF2CH2)
106				-125.0 (2F, CF2CF2CH2)
107				-126.6 (2F, CF3CF2)
108	6c (see Tetrahedron. 1995, 51, 13073-13088)	C32 H43 F13 N2 O4	CDCl3	-81.3 (3F, CF3)			Tetrahedron. 1995, 51, 13073-13088
109				-114.9 (2F, CF2CH2)
110				122.4, -123.4, -124.1 (2F, 2F, 2F, (CF2)3CF2CH2)
111				-126.6 (2F, CF3CF2)
112	cis-1-amino-3-hydroxy-3-(trifluoromethyl)cyclobutanecarboxylic acid hydrochloride (cis-6 .HCl)	C6 H9 Cl F3 N O3	D2O	-84.04	s		Angew. Chem. Int. Ed.2013,52, 1486 –1489	also considered as threonine derivative
113	Isopropyl cis-3-(benzyloxy)-1-(tert-butoxycarbonyl)-3-(trifluoromethyl)cyclobutanecarboxylate (cis- 11)	C21 H28 F3 N O5	CDCl3	-78.43	s		Angew. Chem. Int. Ed.2013,52, 1486 –1489
114	cis-3-(benzyloxy)-1-(tert-butoxycarbonyl)-3-(trifluoromethyl)cyclobutanecarboxylic acid (cis-12)	C18 H22 F3 N O5	CDCl3	-79.34	s		Angew. Chem. Int. Ed.2013,52, 1486 –1489
115	cis-1-amino-3-(benzyloxy)-3-(trifluoromethyl)cyclobutanecarboxylic acid hydrochloride (cis-13)	C13 H15 Cl F3 N O3	DMSO-d6	-77.31	s		Angew. Chem. Int. Ed.2013,52, 1486 –1489
116	cis-1-([(9H-fluoren-9-yl)methoxy]carbonyl)-3-(benzyloxy)-3-(trifluoromethyl) cyclobutanecarboxylic acid (cis-14)	C28 H23 F3 N O5	DMSO-d6	77.94	s		Angew. Chem. Int. Ed.2013,52, 1486 –1489
117
118
119
120
121
122
123
124	Threonine derivatives
125
126
127
128
129
130	Tryptophan derivatives
131	4-Fluoro-L-tryptophan	C11 H11 F N2 O2	CD3OH	-123.8			Advanced Chemistry Development, Inc.
132	5-Fluoro-L-tryptophan	C11 H11 F N2 O2		-127.7			Biochem. 1986, 25, 4240-4249
133	(3S)-2,3-Dihydro-5-fluoro-L-tryptophan			-48.74			Biochem. 1986, 25, 4240-4249
134	6-fluorotryptophan	C11 H11 F N2 O2	CD3OH	-122			Biochem. 2004, 43, 1432-1439
135	7-fluorotryptophan	C11 H11 F N2 O2	CD3OH	-135.2			Advanced Chemistry Development, Inc.
136
137
138	Tyrosine derivatives
139	3-fluorotyrosine	C9 H10 F N O3
140
141
142
143
144	Valine derivatives
145	(2S,3S)-4,4,4-Trifluorovaline		D2O/1% CF3CO2H	-71.62	s		https://pubs.acs.org/doi/10.1021/jo900654y


1	Compound	Formula	Solvent	Chemical Shift (vs CFCl3 = 0)	Splitting Pattern	Coupling Constant in Hz (0 if not observed or m)	Literature Reference or Group data	Notes

2	MoF6	F6 Mo	not reported	278	s	0	CAS Fluorine-19 NMR Spectrum for 7783-77-9
3	WF6	F6 W	not reported	165	s	0	Chem. Rev. 2015, 115, 1296-1306
4	SOF2	F2 O S	not reported	74.5	s	0	Angew Chem. Int. Ed. 2012, 51, 7847-7849
5	SF6	F6 S	D2O	58.14	s	0	Chem. Commun. 2011, 47, 457-459
6	SeF6	F6 Se	not reported	54	s	0	Chem. Rev. 2015, 115, 1296-1306
7	SO2F2	F2 O2 S	not reported	33.5	s	0	Angew Chem. Int. Ed. 2012, 51, 7847-7849
8	[PF4]-	F4 P	CH3CN	9.3	dt	660, 108	J. Am. Chem. Soc. 1994, 116, 2850-2858	axial fluorine
9	BaF2	Ba F2	not reported	-13	s	0	Angew Chem. Int. Ed. 2012, 51, 7847-7849
10	Cis-Pt(CF3)2(DMSO)2 (DMSO bound by O and S)		CDCl3	-18.3 (trans to O bound DMSO) -30.3 (trans to S bound DMSO)
11		C52 H40 F12 Ni O4 P2 S	MeCN - d3	-19.15, -30.6	sept, sept	7.3, 7.3	Inorg. Chem. 2020, 59, 9143-9151
12	[Ni(CF3)4(MeCN)2]	C8 H6 F12 N2 Ni	MeCN - d3	-19.2, -30.07	sept, sept	7.2, 7.2	Angew. Chem. Int. Ed. 2021, 60, 18162-18167
13	[(MeCN)Ni(CF3)5]-	C7 H3 F15 N Ni	MeCN - d3	-19.6, -28.8	app. undecet, q	8.2, 8.2	Angew. Chem. Int. Ed. 2021, 60, 18162-18167
14	CsOCF3	C Cs F3 O	THF	-21	br s	0	Angew Chem. Int. Ed. 2019, 58, 2392-2396
15	[NBu4]2[(PhO)Ni(CF3)3]	C41 H77 F9 N2 Ni O	MeCN - d3	-21.2, -31.3	sept, q	4.1, 4.1	Inorg. Chem. 2020, 59, 9143-9151
16
17	AgCF3	C Ag F3	dmf	-22.4	d	121.7	Inorg. Chem. 1997, 36, 1464-1475	Ag-F coupling constant
18	Cis-Pt(CF3)2(NCCH3)(OC(CH3)2)		(CD3)2CO	-22.8 (trans to (CH3)2CO) -30.0 (trans to NCCH3)
19	Pt(CF3)2(en)		(CD3)2CO	-23.7
20		C7 H2 F15 N Ni	MeCN - d3	-24.3, -27.4	app. septet, q	7.5, 7.5	Angew. Chem. Int. Ed. 2021, 60, 18162-18167
21	Pt(CF3)2(tmen)		(CD3)2CO	-24.5
22	[Ni(CF3)6]2-	C6 F18 Ni	MeCN - d3	-25.1	s	0	Angew. Chem. Int. Ed. 2021, 60, 18162-18167	putative
23	cis-Pt(CF3)2(DMSO)2 (Both DMSO bound by S)		CDCl3	-25.2
24	Pt(CF3)2(bipy)		(CD3)2CO	-25.2
25	[NMe4][(MeCN)Ni(CF3)3]	C9 H15 F9 N2 Ni	MeCN - d3	-25.2, -31.04	sept, q	4.4, 4.4	Angew. Chem. Int. Ed. 2021, 60, 18162-18167
26	[Ag(CF3)2]-	C2 Ag F6	dmf	-25.3	d	100.1	Inorg. Chem. 1997, 36, 1464-1475	Ag-F coupling constant
27	Cis-Pt(CF3)2(NCCH3)2		CD3CN	-26.1		859.4
28		C52 H40 F12 Ni P2	MeCN - d3	-26.24	s	0	Inorg. Chem. 2020, 59, 9143-9151
29	Cis-Pt(CF3)2(DMSO)2		(CD3)2CO	-26.4		864.3
30	Cis-Pt(CF3)2(NH3)2		(CD3)2CO	-26.5
31	AgOCF3	C Ag F3 O	CD3CN	-26.8	s	0	Organometallics 2012, 31, 7812-7815
32	Cis-Pt(CF3)2py2		(CD3)2CO	-26.9
33	[Cu(CF3)(I)]-	C Cu F3 I	CDCl3	-27.8	s	0	J. Am. Chem. Soc. 2021, 143, 14367-14378
34	[(MeCN)2Ni(CF3)2	C6 H6 F6 N2 Ni	MeCN - d3	-27.8	s	0	Angew. Chem. Int. Ed. 2021, 60, 18162-18167
35	[Cu(Cl)(CF3)]-	C49 H56 F3 Cl Cu2	CD2Cl2	-28.17	s	0	J. Fluorine Chem. 2020, 234, 109518
36	[Cu(CF3)2]	C2 Cu F6	CD2Cl2	-32.06	s	0	J. Fluorine Chem. 2020, 234, 109518
37	[Cu(CF3)(CF2CF3)]-	C3 Cu F8	CD2Cl2	-32.14	s	0	J. Fluorine Chem. 2020, 234, 109518
38	[Ag(CF3)4]-	C4 Ag F12	MeCN	-32.3	d	40.7	Chem. Eur. J. 2021, 27, 15396-15405
39	[(SIMes)Cu(CF3)]	C24 H28 Cu F3	CD2Cl2	-33.25	s	0	J. Fluorine Chem. 2020, 234, 109518
40	Pt(CF3)2(NBD)		(CD3)2CO	-35.1
41	[PF4]-	F4 P	CH3CN	-46.3	dt	1405, 108	J. Am. Chem. Soc. 1994, 116, 2850-2858	equatorial F
42	TeF6	F6 Te	not reported	-56.4	s	0	Chem. Rev. 2015, 115, 1296-1306
43	(NHC)2 Ni(F) (CF2Ph)	C25 H37 F3 N4 Ni	THF-d8	-71.7	d	17	J. Am. Chem. Soc. 2020, 142, 19360-19367	Ni-CF2Ph resonance
44	[PPh4][(Tp)Co(CF2CF3)]	C39 H30 B Co F15 N6 P	MeCN - d3	-78.7	s	0	Helv. Chim. Acta 2020, 103, e2000149
45	[NMe4][(MeCN)Ni(CF2CF3)3]	C12 H15 F15 N2 Ni	MeCN - d3	-79	q	8.6	Angew. Chem. Int. Ed. 2021, 60, 18162-18167
46	[(terpyridine)Co(CF2CF3)3]	C21 H11 Co F15 N3	CD2Cl2	-79.07	p	14.8	Organometallics 2019, 38, 3169-3173
47	[mer-(MeCN)(bipyridine)Co(CF2CF3)3]	C18 H11 Co F15 N3	MeCN - d3	-79.63	app sept	12.1	Organometallics 2019, 38, 3169-3173
48	[(terpyridine)Co(CF2CF3)3]	C21 H11 Co F15 N3	CD2Cl2	-80.78	t	8.5	Organometallics 2019, 38, 3169-3173
49	[fac-(MeCN)3Co(CF2CF3)3]	C12 H9 Co F15 N3	MeCN - d3	-81.1	s	0	Organometallics 2019, 38, 3169-3173
50	[NMe4][(MeCN)Ni(CF2CF3)3]	C12 H15 F15 N2 Ni	MeCN - d3	-81.2	t	5.6	Angew. Chem. Int. Ed. 2021, 60, 18162-18167
51	[mer-(MeCN)(bipyridine)Co(CF2CF3)3]	C18 H11 Co F15 N3	MeCN - d3	-81.72	t	5.5	Organometallics 2019, 38, 3169-3173
52	[Cu(CF3)(CF2CF3)]-	C3 Cu F8	CD2Cl2	-84.98	s	0	J. Fluorine Chem. 2020, 234, 109518
53	[Cu(CF2CF3)2]-	C4 Cu F10	CD2Cl2	-85.01	s	0	J. Fluorine Chem. 2020, 234, 109518
54	[Cu(Cl)(CF2CF3)]-	C2 Cl Cu F5	CD2Cl2	-85.1	s	0	J. Fluorine Chem. 2020, 234, 109518
55	[(SIMes)Cu(CF2CF3)]	C25 H28 Cu F5	CD2Cl2	-85.64	s	0	J. Fluorine Chem. 2020, 234, 109518
56	[PPh4][(Tp)Co(CF2CF3)3]	C39 H30 B Co F15 N6 P	MeCN - d3	-90.3	s	0	Helv. Chim. Acta 2020, 103, e2000149
57	[mer-(MeCN)(bipyridine)Co(CF2CF3)3]	C18 H11 Co F15 N3	MeCN - d3	-93.86	m	0	Organometallics 2019, 38, 3169-3173	m spans range
58	[fac-(MeCN)3Co(CF2CF3)3]	C12 H9 Co F15 N3	MeCN - d3	-95.6	s	0	Organometallics 2019, 38, 3169-3173
59	[(terpyridine)Co(CF2CF3)3]	C21 H11 Co F15 N3	CD2Cl2	-96.08	m	0	Organometallics 2019, 38, 3169-3173	m spans range
60	[NMe4][(MeCN)Ni(CF2CF3)3]	C12 H15 F15 N2 Ni	MeCN - d3	-97.2	m	0	Angew. Chem. Int. Ed. 2021, 60, 18162-18167	m spans range
61	[mer-(MeCN)(bipyridine)Co(CF2CF3)3]	C18 H11 Co F15 N3	MeCN - d3	-99.93	m	0	Organometallics 2019, 38, 3169-3173	m spans range
62	[mer-(MeCN)(bipyridine)Co(CF2CF3)3]	C18 H11 Co F15 N3	MeCN - d3	-100.71	m	0	Organometallics 2019, 38, 3169-3173	m spans range
63	[(terpyridine)Co(CF2CF3)3]	C21 H11 Co F15 N3	CD2Cl2	-103.84	m	0	Organometallics 2019, 38, 3169-3173	m spans range
64	[mer-(MeCN)(bipyridine)Co(CF2CF3)3]	C18 H11 Co F15 N3	MeCN - d3	-104.82	m	0	Organometallics 2019, 38, 3169-3173	m spans range
65	[mer-(MeCN)(bipyridine)Co(CF2CF3)3]	C18 H11 Co F15 N3	MeCN - d3	-105.53	m	0	Organometallics 2019, 38, 3169-3173	m spans range
66	[(MeCN)2Ni(C4F8)]		MeCN - d3	-106.0, -139.4	s, s	0	Organometallics, 2013, 32, 7552-7558
67	CaF2	Ca F2	not reported	-107	s	0	Angew Chem. Int. Ed. 2012, 51, 7847-7849
68	[NMe4][(MeCN)Ni(CF2CF3)3]	C12 H15 F15 N2 Ni	MeCN - d3	-108.4	m	0	Angew. Chem. Int. Ed. 2021, 60, 18162-18167	m spans range
69	[Cu(Cl)(CF2CF3)]-	C2 Cl Cu F5	CD2Cl2	-113.56	s	0	J. Fluorine Chem. 2020, 234, 109518
70	[Cu(CF3)(CF2CF3)]-	C3 Cu F8	CD2Cl2	-118.01	s	0	J. Fluorine Chem. 2020, 234, 109518
71	[Cu(CF2CF3)2]-	C4 Cu F10	CD2Cl2	-118.04	s	0	J. Fluorine Chem. 2020, 234, 109518
72	[(SIMes)Cu(CF2CF3)]	C25 H28 Cu F5	CD2Cl2	-119.43	s	0	J. Fluorine Chem. 2020, 234, 109518
73	F-	F	D2O	-121.4	s	0	Dalton Trans., 2013, 42, 4299–4305
74		C14 H26 F4 N4 O2 Zn	CD2Cl2	-128.83	d	39.4	J. Am. Chem. Soc. 2016, 138, 2536-2539.
75	SiF6 2-	F6 Si	D2O	-130.5	s	0	Dalton Trans., 2013, 42, 4299–4305
76	[PF6]-	F6 P	THF-d8	-138.4	d	255.2	Organometallics 2021, 40, 3585-3590	Counter-ion for cobalt complex
77	Difluoromethyl Trimethyl silane			-140			Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
78	HF2 -	H F2	D2O	-150	s	0	Dalton Trans., 2013, 42, 4299–4305
79	[BF4]-	B F4	CD3CN	-152	s	0	Organometallics 2021, 40, 3585-3590	Counter-ion for cobalt complex; -152.16 in CD2Cl2 solvent as counterion for Ni2(µ-F)2(dtbpe) see Inorg. Chim. Acta, 2011, 376, 118-122
80		C52 H96 F2 Ni2 P4 (without counterion) or C52 H96 B F6 Ni2 P4 (with counterion)	CD2Cl2	-152.1	s	0	Inorganica Chimica Acta 2011, 376 ,118–122.
81	BF3 OEt2	C4 H10 B F3	not provided	-154	s	0	Dolbier, W. R. Guide to Fluorine NMR for Organic Chemists, 2nd Edition; John Wiley & Sons, Inc., 2016
82	SiF4	F4 Si	MeCN/CH2Cl2	-162	s	0	Can. J. Chem. 1977, 55, 3845-3849	will have Si-F couplings too
83	HF	H F	not provided	-200	s	0	Angew Chem. Int. Ed. 2012, 51, 7847-7849	-164.4 ppm in D2O (ref: Dalton Trans., 2013, 42, 4299–4305)
84	F2O	F2 O	not provided	-248	s	0	Angew Chem. Int. Ed. 2012, 51, 7847-7849
85		C25 H37 F3 N4 Ni	THF-d8	-351.6	t	17	J. Am. Chem. Soc. 2020, 142, 19360-19367	Ni-F resonance
86	F2 (liquid)	F2	not provided	-422	s	0	Angew Chem. Int. Ed. 2012, 51, 7847-7849
87		C60 H40 Co F32 P2	CD2Cl2	-427.3	s	0	J. Organomet. Chem. 2021, 949, 121974	bridging F resonance


1	The authors thank the NSF grant CHE-2153730 for supporting this effort to prepare a living and global 19F NMR database.
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15	We thank the following people for helpful contributions:
16	Cheng-Pan Zhang, Wuhan Institute of Technology