2023 Daily Tech News Show


1			TITLE: What is an Embryo Model?	Guest:

2			Stories subject to change up until showtime
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4		tm	This tenth year of Daily Tech News Show is made possible by its listeners. Thanks to all of you including Carmine Bailey Vince Power Rodrigo Smith-Zapata New Patrons William and Victor!
5			On this episode of DTNS, ... Apple and Epic are still going at it, Raspberry Pi 5 is here, and Dr Niki explains how lab embryos are more evolved than ever!	Twitch Chat Pop-out Window
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7			Today's date	--== START OF DTNS ==--
8			This is the Daily Tech News for... Thursday September 28th, 2023. From Studio Cinnamon I'm Sarah Lane
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10			From Columbus, Ohio, I'm Robb Dunewood
11			From my sweet home in Alabama, I'm Dr. Niki Ackermans
12			And I'm the show's Producer Roger Chang
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15		sl	CEO of Sony Interactive Entertainment Jim Ryan announced he's retiring in March 2024 after almost 30 years with the company. Hiroki Totoki, president and chief financial officer of parent Sony Group Corp., will become interim CEO of the games business once Ryan departs.	https://www.bloomberg.com/news/articles/2023-09-27/playstation-boss-jim-ryan-is-retiring-from-sony-in-march
16	:01	sl	Let's start with the Quick Hits.
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18			Quick Hits	Quick Hits:
19		sl	Yesterday we passed along a report from The Information that OpenAI CEO Sam Altman is working with former Apple designer Jony Ive to build a hardware device. Today, the Financial Times' sources say OpenAI is in advanced talks with Ive and SoftBank’s Masayoshi Son to launch a consumer device described as the “iPhone of artificial intelligence”. The hope, reportedly, is to create a more natural and intuitive user experience for interacting with AI.	https://www.ft.com/content/4c64ffc1-f57b-4e22-a4a5-f9f90a7419b7
20			---	https://www.macrumors.com/2023/09/28/jony-ive-iphone-artificial-intelligence-openai/
21		rd	After nearly two years in beta, Photoshop the web service, a simplified online version of the company’s desktop photo editing app, is now available to all. Photoshop on the web offers commonly used tools like Generative Fill and Generative Expand powered by Adobe’s Firefly generative AI model, but with a redesigned layout designed to give new users a more “streamlined” experience.	https://www.theverge.com/2023/9/27/23892889/adobe-photoshop-for-the-web-firefly-ai-generative-fill-full-release-price-date
22		sl	Apple launched a new iPhone Wallet beta feature for UK users, which lets them see their current account balance, recent deposits and payments, and balances after using Apple Pay. The new features use the UK's Open Banking API and follow Apple's acquisition of a company called Credit Kudos - which uses Open Banking to give users a snapshot of their financial health and credit score. Banks including Barclays, HSBC, Lloyds, RBS, Monzo, and Starling are all on board, and this integration is rolling out first as part of the upcoming iOS 17.1 developer beta.	https://www.engadget.com/apple-wallet-can-now-show-uk-users-their-bank-account-balances-113554313.html
23		rd	OpenAI said in a post on X that it has expanded the data ChatGPT can access beyond its September 2021 cut-off and can now surf the web. In OpenAI's own words "Browsing is available to Plus and Enterprise users today, and we'll expand to all users soon. To enable, choose Browse with Bing in the selector under GPT-4." This latest web browsing feature will let websites control how ChatGPT can interact with them.	https://www.reuters.com/technology/openai-says-chatgpt-can-now-browse-internet-2023-09-27/
24		sl	Disney Plus is now alerting Canadian subscribers that, beginning Nov. 1st it will start restricting password sharing in Canada. This announcement came in an email sent to Canadian subscribers but the company didn't say how it plans to enforce the policy. A new “account sharing” section in the Canadian subscriber agreement also notes that Disney may “analyze the use of your account”, and that failing to comply with the agreement could lead to account restriction or termination.	https://www.theverge.com/2023/9/27/23893231/disney-plus-password-sharing-ban-canada
25			play the news segue music here....
26			Let's talk a little more about...	Top Stories:
27	:05		SEGMENT A
28		sl	Apple and Epic just can't seem to get along. Here's the latest, Apple has asked the US Supreme Court to review a judge’s ruling from two years ago that deemed developers should be able direct users to alternative payment methods other than Apple's App Store, where Apple takes a 30% cut of all sales of digital goods and services. Epic, maker of Fortnite, doesn't think it should pay that fee. This follows Wednesday's news of Epic initially asking the same Supreme Court to weigh in on the ongoing dispute.	https://www.bloomberg.com/news/articles/2023-09-28/apple-asks-supreme-court-to-reverse-app-store-ruling-won-by-epic
29		rd	Epic Games sued Apple back in 2020 after Apple kicked Epic out of the App Store for violating Apple’s rules. Initial rulings and appeals on the suit have mostly favored Apple but a federal judge did rule that Apple violated California’s Unfair Competition Law by restricting developers from telling consumers about alternative payment options. We’re probably not going to know if the SCOTUS will select the case for a few months based on the SCOTUS schedule.	https://www.bloomberg.com/news/articles/2023-09-27/apple-app-store-ruling-challenged-at-supreme-court-by-epic-games
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31		sl	In other Epic news, CEO Tim Sweeney is also confirming reports that the company is laying off 830 employees, or about 16% of its workforce. Sweeney also says Epic will divest from indie music storefront Bandcamp which Epic acquired just last year — and also plans to spin off SuperAwesome which makes safe online experiences for kids. Candidly, Sweeney says Epic is “spending way more money than we earn.”	https://www.bloomberg.com/news/articles/2023-09-28/epic-games-is-cutting-about-900-jobs-or-16-of-staff
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36	:11		SEGMENT B
37		rd	It’s been 4 long years since the release of the Raspberry Pi 4, and, though there was speculation that its successor wouldn’t be available until later this year, if not next, the Raspberry Pi 5, along with its $60 starting price tag, is available for pre-order today and will be available for purchase by the end of next month.	https://www.theverge.com/2023/9/28/23889238/raspberry-pi-5-specs-availability-pricing
38		sl	There are noticeable improvements made on the Raspberry Pi 5, including its 64-bit quad-core Arm Cortex-A76 processor that runs at 2.4GHz, allowing for a two to three times performance boost when compared to the Raspberry Pi 4. The device also comes with an 800MHz VideoCore VII graphics chip, two four-lane 1.5Gbps MIPI transceivers that let you connect up to two cameras or displays, and a single-lane PCI Express 2.0 interface offering support for “high-bandwidth peripherals.”, but you’ll still need a separate adapter, such as an M.2 HAT (Hardware Attached on Top) for you to take advantage of it.	https://www.raspberrypi.com/news/introducing-raspberry-pi-5/
39		rd	The Raspberry Pi 5 also boasts dual 4Kp60 HDMI display outputs with support for HDR, a microSD slot, two USB 3.0 ports, two USB 2.0 ports, gigabit ethernet, a 5V DC power connection via USB-C, and Bluetooth 5.0 with Bluetooth Low Energy.
40		sl	Alright Robb, I know you've got a good use case for this.
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44		sl	Have a thought about something on the show but don't know our email address? Here it is! Email us feedback@dailytechnewsshow.com
45			PAUSE PAUSE PAUSE
46			More Discussion Stories	Discussion Story:
47	:16		SEGMENT D
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49		sl	Earlier this month, scientists at Weizmann Institue in Israel published research in the journal Nature reporting the creation of an early human embryo using only stem cells and without the aid of sperm, egg or a womb. The team took adult human stem cells, collected from skin cells, and cultured them in their lab. The model resembles an embryo at day 14. The team's next goal is to achieve a model at 21 days of development with a 50% success rate. -0- So, Niki can you break this down for us? What is an embryo model and is it the same thing as an actual embryo?	https://www.bbc.com/news/health-66715669
50			---	https://www.nature.com/articles/s41586-023-06604-5
51		NA	Usually, for embryology research, donated embryos are used. However in this case, because this embryo is created in a lab from scratch, it is a model representing a human embryo. The endgoal for this type of technology is to eliminate that sample scarcity that comes with using donor tissue and, it may also reduce some ethical limitations.
52		SL	-0- Is this the first time this has ever been done?
53			-0- A short timeline: first model embryo developed from stem cells only, was made in mice in 2012. Then, the first human oocyte (egg cell) made from stem cells in vitro was in 2018. So this is the next logical step.
54		SL	-0- Why is this such a big deal?
55		NA	-0- This is a synthetic model that starts out as a handful of pluripotent stem cells, meaning they have the possibility to become almost any different type of cell. These specific cells are capable of self-assembling into an embryo model (post gastrulation, meaning the inner tube is already in place). At the oldest stage, 14 days, over four different cell types and layers have differentiated from these original hundred or so stem cells. This model showed key developmental stages in vitro that would normally be seen up to 14 days after a human egg cell or oocyte’s fertilization. So it is developing just like a human embryo would in utero, which is pretty incredible.
56			-0- how does one make a synthetic embryo?
57			-0- The interesting part of this paper to me is the way in which they achieved this. Of course it takes years of experimentation on mouse and then human cells to get to this point but they developed a kind of recipe of how many of each stem cell type they need to create a complete embryo. And I can share the recipe with you. Take 120 pluripotent stem cells from a human cell line and let them grow for three days. Continue the culture in an orbital shaker to maintain the morphology using ex-utero cell culture media. (aka secret sauce). After 8 days you will get a spherical structure with tissue compartments and self organization. By days 11-12 you gey fully differintiated cells forming structured tissue layers and expressing growth factors that make the cells move and change shape to form gastrulation, aka what will become the inside part of the human straw. The synthetic embryos are inspected microscopically at all of these stages and match the structure ans molecular properties of human embryos. The goal of this research is to better understand fertility and developmental defects. However this type of work is rife with ethical and technical challenges. Of course this study has a limiting factor, and that is a low success rate. In addition to requiring much more testing to see whether these embryo models can survive after 14 days. So as usual, a lot more work has to be done
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61	:25	sl	Kicker - OPTIONAL	Kicker:
62			If you're tired of junk fees tacked on everytime you travel, Chris Christensen has some news for you.	amateurtraveler.com
63			TRT 00:00:56	https://www.latimes.com/california/story/2023-02-14/free-from-fees-california-introduces-bill-to-combat-junk-fees-for-everything-from-concert-tickets-to-groceries	https://www.dropbox.com/scl/fi/nz2cjzd2gvaybptieisel/235-Tech-in-Travel.wav?rlkey=zgk0hheuqasxh0sxp9qf9mmgo&dl=0
64			---	https://www.sfgate.com/california-politics/article/california-eliminate-hidden-concert-hotel-fees-17828059.php
65			"This is Chris Christensen from Amateur Traveler with another Tech in Travel Minute... ... But it looks like some help may be coming for those of us who are tired of junk fees , this is Chris Christensen from Amateur Traveler."
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68		tm	Let's check out the mailbag
69			[PLAY MAILBAG SOUND]
70	:26	sl	Mailbag (feedback@dailytechnewsshow.com)	Mailbag:
71			We asked for foldable laptop feedback and got a ton! Joshlama from Sydney Australia wrote in - "I can see some positives in having a foldable laptop for the use of web development or for IT administrative jobs where a vertical screen on the go may be preferred over a horizontal screen. Making the Keyboard/Mouse external could give a lot of flexibility, but then you’re carrying around extra peripherals. The closest contender to a foldable laptop on the market today would be the attempts to sell that a Mobile OS can do everything that a Desktop OS can do. Think Samsung DeX which turns your phone into a Chromebook-esque virtual machine with a dock, or iPadOS Split View. But at this time, we haven’t seen widespread attempts of that working. Developers have experimented to make the iPad Pro their main workstation have ran into issues with multitasking and working within the form factor. DeX hasn’t gotten a whole heap of attention since its launch in 2017. There’s something about the laptop form factor that makes it just work. That being said, I can’t justify the $4000 asking price." Andrew from Melbourne wrote: "Working in tech, I like using machines with large screen real-estate while also being portable. If they have a high viewing position then that's even better. I currently use a GPD WinMax 2 with a portable 16" external monitor when I'm on the go, but having a foldable portable external monitor that could be powered (and receive signal) via USB C displaying up to 30" would be ideal. It would fit in the backpack while folded and I'd have a beast that could be taken out when I need to do some real work (read play a few games away from home). "
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73		rd	Benjamin from Boone, Iowa wrote: "I am a mechanical keyboard enthusiast. I would love a foldable laptop that I could use without a built in keyboard and plug in my mechanical keyboard in instead provided there was more than one USB port. It would be a useful item. The price is way out of my price range, but it is a promising technology and I may buy one when the prices come down in future years. "
74	:28	sl	Thanks to...	Today’s guest:
75			Dr. Niki Ackermans	Dr. Niki Ackermans https://www.nicoleackermans.com @AckermansNicole @nicoleackermans.bsky.social	https://twitter.com/AckermansNicole	https://www.nicoleackermans.com
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79			GUEST PLUG 15 SECONDS MAX
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86		rd	It's free Preview week! All this week we are giving everyone access to the Good-Day-Internet extended show. So stick around for GDI as we discuss what your Zoom background (or any video chat background) says about you.
87			play the end theme music here....
88		sl	You can also catch the show live M-F at 4:00 PM eastern/20-hundred UTC find out more at dailytechnewsshow.com/live. We'll be back tomorrow with:	Next guest:
89		sl	Tristan Jutras	Tristan Jutras https://tristanjutras.com https://www.ainamedthisshow.com https://www.momentous.tv @tristanjutras @tristanjutras.bsky.social
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95				Show Links: http://dailytechnewsshow.com/ntx http://knowalittlemore.com http://dtns.bigcartel.com http://www.dailytechnewsshow.com/support http://dtns.tv/wiki http://sarahlane.com https://twitter.com/sarahlane https://medium.com/@sarahlane https://masto.ai/@sarahlane https://havesuchagoodday.com http://tomsnewbook.com http://swordandlaser.com/store http://www.cordkillers.com http://awordpodcast.com
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98			GDI CONTENT - Quiz/game/content?	GDI Content:
99		rd	Researchers at Durham University in the UK released a study published in the Public Library of Science titled "Virtual first impressions: Zoom backgrounds affect judgements of trust and competence." The study compared how 167 adults judged pictures of Zoom participant's faces against different backgrounds. Each image featured a man or woman with a similing or neutral expression. The backgrounds tested were a blurred living space, houseplants, a bookcase, an empty wall, and a novelty image of a walrus. The faces placed against a houseplant or bookcase background were judged the most competent and trustworthy and faces over the novelty picture or living space were judged the least competent or trustworthy. The study also noted more research is needed to confirm these findings and if they apply across cultural contexts. All the particpant faces were of white individuals.	https://phys.org/news/2023-09-background.html
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102			Thanks to Ross for the Patreon raise!
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104			END OF DTNS SHOW NOTES	--== END OF DTNS SHOW NOTES ==--
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106			Tell Audience to VOTE on TITLES
107			TITLES (we do Titles after GDI) - Maybe Quiz/game	Submitted
108		DTNS	What is an Embryo Model?	zoebringsbacon
109		GDI	Your Zoom Background Speaks Volumes	gpeg84
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118			YouTube Shorts Clips Recco:
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126			Friday: Read the list of Credits
127			ROTATING PROMOS
128			Know A Little More is Tom's podcast to do deep dives into individual topics. And it's coming back this Thursday better than ever. If you have not yet sampled the show, go get subscribed right now. The first episode in the relaunch is about RSS, its rocky history and how it ended up being the underpinning of podcasting. Don't miss it. Subscribe by Thursday at knowalittlemore.com	Subscribe to Know A Little More: http://knowalittlemore.com
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134			Watch Tom'sTop Five. The show where I break down the top five things you need to know about technology. Everything from online services and AI to security and tech legislation. You can catch it at youtube dot com slash daily tech news show!	Check out Tom’s Top Five: https://www.youtube.com/playlist?list=PLHN12N7TXUyeSz1XWNVjwDvdzpAycENQi
135			Thanks to everyone who became new Patrons and increased their pledges, because of your support we can bring Molly Wood on the show one Friday every other month. But to reach our goal of having Molly one Friday every month we need a bit MORE help! If you haven't already, consider supporting the show by visiting patreon.com slash D-T-N-S!"	Help Bring Molly Wood to the Show: https://www.patreon.com/dtns
136			Android aficiandos Ron Richards and Huyen Tue Dao bring you Android Faithful! A podcast devoted exclusively to Android news and information! Catch it Tuesdays at 8PM East Coast / 5PM Pacific. Watch it Live or subscribe to it right now at www-dot-androidfaithful-dot-com!	Subscribe to Android Faithful: https://androidfaithful.com
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138			All next week is DTNS Experiment week! We're swapping out our normal DTNS show and trying out some new ideas. In previous years we launched shows like BBQ tech show and The Tech Jawn. This year we have Nicole Lee with a show about online life, Roger interviewing people and personalities who made the TechTV network possible just to name a few. It all starts next week Monday Aug 14th on the DTNS feeds.
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