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1 | Anatomical Structures, Cell Types and Biomarkers Table for Large Intestine | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
3 | Author Name(s): | Teri A. Longacre; John Hickey; Yiing Lin | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
4 | Author ORCID(s): | 0000-0002-0935-7300; 0000-0001-5675-3974; 0000-0002-0317-7608 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
5 | Reviewer(s): | Aaron Horning; Mark Arends; Ellen Quardokus; Supriya Bidanta | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
6 | Reviewer ORCID(s): | 0000-0003-3247-0798; 0000-0002-6826-8770; 0000-0001-7655-4833; 0000-0002-2142-983X | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
7 | General Publication(s): | https://doi.org/10.1007/978-1-4939-0897-4_3; https://doi.org/10.1111/j.1440-1827.1989.tb02421.x; https://doi.org/10.1016/j.immuni.2020.02.001 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
8 | Data DOI: | https://doi.org/10.48539/HBM325.ZPWW.358 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
9 | Date: | June 15, 2025 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
10 | Version Number: | v1.4 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11 | AS/1 | AS/1/LABEL | AS/1/ID | AS/2 | AS/2/LABEL | AS/2/ID | AS/3 | AS/3/LABEL | AS/3/ID | AS/4 | AS/4/LABEL | AS/4/ID | AS/4/NOTES | AS/5 | AS/5/LABEL | AS/5/ID | CT/1 | CT/1/LABEL | CT/1/ID | CT/1/NOTES | BGene/1 | BGene/1/LABEL | BGene/1/ID | BGene/2 | BGene/2/LABEL | BGene/2/ID | BGene/3 | BGene/3/LABEL | BGene/3/ID | BGene/4 | BGene/4/LABEL | BGene/4/ID | BGene/5 | BGene/5/LABEL | BGene/5/ID | BGene/6 | BGene/6/LABEL | BGene/6/ID | BProtein/1 | BProtein/1/LABEL | BProtein/1/ID | BProtein/2 | BProtein/2/LABEL | BProtein/2/ID | BProtein/3 | BProtein/3/LABEL | BProtein/3/ID | BProtein/4 | BProtein/4/LABEL | BProtein/4/ID | BProtein/5 | BProtein/5/LABEL | BProtein/5/ID | BProtein/6 | BProtein/6/LABEL | BProtein/6/ID | FTU/1 | FTU/1/LABEL | FTU/1/ID | REF/1 | REF/1/ID | REF/1/NOTES | REF/2 | REF/2/ID | REF/2/NOTES | REF/3 | REF/3/ID | ||||||||||||
12 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | epithelium | colonic epithelium | UBERON:0000397 | absorptive | enterocyte of epithelium of large intestine | CL:0002071 | keratin 20 | HGNC:20412 | BEST4 | HGNC:17106 | keratin 20 | HGNC:20412 | BEST4 | HGNC:17106 | PMID:32814826 PMCID:PMC7438495 | https://doi.org/10.1038/s42003-020-01181-z | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
13 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | epithelium | colonic epithelium | UBERON:0000397 | goblet | large intestine crypt goblet cell | CL:1000321 | keratin 20 | HGNC:20412 | MUC2 | HGNC:7512 | keratin 20 | HGNC:20412 | MUC2 | HGNC:7512 | PMID:32814826 PMCID:PMC7438495 | https://doi.org/10.1038/s42003-020-01181-z | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
14 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | epithelium | epithelium of crypt of Lieberkuhn | UBERON:0011184 | epithelial stem cell | intestinal crypt stem cell of large intestine | CL:0009016 | RGMB | HGNC:26896 | SOX9 | HGNC:11204 | CD44 | HGNC:1681 | Lgr5 | HGNC:4504 | LRIG1 | HGNC:17360 | SMOC2 | HGNC:20323 | RGMB | HGNC:26896 | SOX9 | HGNC:11204 | CD44 | HGNC:1681 | Lgr5 | HGNC:4504 | LRIG1 | HGNC:17360 | SMOC2 | HGNC:20323 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:17934449 | https://doi.org/10.1038/nature06196 | ||||||||||||||||||||||||||||||||
15 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | epithelium | epithelium of crypt of Lieberkuhn | UBERON:0011184 | Paneth | paneth cell of epithelium of large intestine | CL:0009009 | DEFA5 | defensin alpha 5 | HGNC:2764 | DFA5 | defensin alpha 5 | HGNC:2764 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:19269007 | https://doi.org/10.1016/j.humpath.2008.12.003 | ||||||||||||||||||||||||||||||||||||||||||||||||||
16 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | epithelium | epithelium of crypt of Lieberkuhn | UBERON:0011184 | neuroendocrine | neuroendocrine cell | CL:0000165 | chromogranin A | HGNC:1929 | synaptophysin | HGNC:11506 | INSM1 | HGNC:6090 | INSL5 | HGNC:6088 | chromogranin A | HGNC:1929 | synaptophysin | HGNC:11506 | INSM1 | HGNC:6090 | INSL5 | HGNC:6088 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:31390635 PMCID:PMC6888884 | https://doi.org/10.1159/000501521 | ||||||||||||||||||||||||||||||||||||||||
17 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | epithelium | epithelium of crypt of Lieberkuhn | UBERON:0011184 | absorptive | enterocyte of epithelium of large intestine | CL:0002071 | keratin 20 | HGNC:20412 | BEST4 | HGNC:17106 | keratin 20 | HGNC:20412 | BEST4 | HGNC:17106 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:32814826 PMCID:PMC7438495 | https://doi.org/10.1038/s42003-020-01181-z | ||||||||||||||||||||||||||||||||||||||||||||||||
18 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | epithelium | epithelium of crypt of Lieberkuhn | UBERON:0011184 | goblet | large intestine crypt goblet cell | CL:1000321 | keratin 20 | HGNC:20412 | MUC2 | HGNC:7512 | keratin 20 | HGNC:20412 | MUC2 | HGNC:7512 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:32814826 PMCID:PMC7438495 | https://doi.org/10.1038/s42003-020-01181-z | ||||||||||||||||||||||||||||||||||||||||||||||||
19 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | epithelium | epithelium of crypt of Lieberkuhn | UBERON:0011184 | transient amplifying cell | transit amplifying cell of colon | CL:0009011 | keratin 20 | HGNC:20412 | keratin 20 | HGNC:20412 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:32814826 PMCID:PMC7438495 | https://doi.org/10.1038/s42003-020-01181-z | ||||||||||||||||||||||||||||||||||||||||||||||||||||
20 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | epithelium | epithelium of crypt of Lieberkuhn | UBERON:0011184 | tuft cell | intestinal tuft cell | CL:0019032 | keratin 20 | HGNC:20412 | DCLK1 | HGNC:2700 | TRPM5 | HGNC:14323 | POU2F3 | HGNC:19864 | PTGS1 | COX-1 | HGNC:9604 | keratin 20 | HGNC:20412 | DCLK1 | HGNC:2700 | TRPM5 | HGNC:14323 | POU2F3 | HGNC:19864 | PTGS1 | COX-1 | HGNC:9604 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:32814826 PMCID:PMC7438495 | https://doi.org/10.1038/s42003-020-01181-z | PMID:31767912 PMCID:PMC6877571 | https://doi.org/10.1038/s41598-019-53997-3 | PMID:30782851 PMCID:PMC6383804 | https://doi.org/10.4049/jimmunol.1801069 | ||||||||||||||||||||||||||||||
21 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lymphocyte | colonic epithelium | UBERON:0000397 | Tissue resident lymphocytes; interepithelial lymphocytes | surface intraepithelial CD8+ alph alpha positive alpha/beta lymphocyte | CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell | CL:0000915 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | CD3-TCR | HGNC:1673 | CD8 | HGNC:1706 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | TCR alpha/beta | HGNC:1673 | CD8 | HGNC:1706 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:7495755 | https://doi.org/10.1093/intimm/7.9.1473 | ||||||||||||||||||||||||||||||||||
22 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lymphocyte | colonic epithelium | UBERON:0000397 | Tissue resident lymphocytes; interepithelial lymphocytes | surface intraepithelial CD8+ lymphocyte gamma/delta | CD8-alpha alpha positive, gamma-delta intraepithelial T cell | CL:0000802 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | CD3-TCR | HGNC:1673 | CD8 | HGNC:1706 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | TCR gamma/delta | HGNC:1673 | HGNC:1706 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:7495755 | https://doi.org/10.1093/intimm/7.9.1473 | |||||||||||||||||||||||||||||||||||
23 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lymphocyte | colonic epithelium | UBERON:0000397 | Tissue resident lymphocytes; interepithelial lymphocytes | surface intraepithelial CD8+ alph beta positive alpha/beta lymphocyte | CD8-alpha-beta-positive, alpha-beta intraepithelial T cell | CL:0000796 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | CD3-TCR | HGNC:1673 | CD8 | HGNC:1706 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | TCR alpha/beta | HGNC:1673 | CD8 | HGNC:1706 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:7495755 | https://doi.org/10.1093/intimm/7.9.1473 | ||||||||||||||||||||||||||||||||||
24 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lymphcyte | colonic epithelium | UBERON:0000397 | Tissue resident lymphocytes; interepithelial lymphocytes | surface intraepithelial CD4+ lymphocyte | CD4-positive, alpha-beta intraepithelial T cell | CL:0000793 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | CD3-TCR | HGNC:1673 | CD4 | HGNC:1678 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1695 | CD5 | HGNC:1685 | TCR alpha/beta | HGNC:1673 | CD4 | HGNC:1678 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:7495755 | https://doi.org/10.1093/intimm/7.9.1473 | ||||||||||||||||||||||||||||||||||
25 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lymphocyte | colonic epithelium | UBERON:0000397 | Tissue resident lymphocytes; interepithelial lymphocytes | surface intraepithelial CD4-CD8- lymphocyte alpha/beta | CD4-negative, CD8-negative, alpha-beta intraepithelial T cell | CL:0000935 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | CD3-TCR | HGNC:1673 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1695 | CD5 | HGNC:1685 | TCR alpha/beta | HGNC:1673 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:7495755 | https://doi.org/10.1093/intimm/7.9.1473 | ||||||||||||||||||||||||||||||||||||||
26 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lamina propria | lamina propria of mucosa of colon | UBERON:0007177 | subepithelial membrane | aSMA | HGNC:130 | aSMA | HGNC:130 | crypt of Lieberkuhn of large intestine | crypt of Lieberkuhn of large intestine | UBERON:0001984 | PMID:2618659 | https://doi.org/10.1111/j.1440-1827.1989.tb02421.x | PMID:12969318 | https://doi.org/10.1034/j.1600-065x.2003.00072.x | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
27 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lamina propria | lamina propria of mucosa of colon | UBERON:0007177 | pericryptal fibroblastic sheath | aSMA | HGNC:130 | WNT2B | HGNC:12781 | RSPO3 | HGNC:20866 | aSMA | HGNC:130 | PMID:2618659 | https://doi.org/10.1111/j.1440-1827.1989.tb02421.x | PMID:12969318 | https://doi.org/10.1034/j.1600-065x.2003.00072.x | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
28 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lamina propria | lamina propria of mucosa of colon | UBERON:0007177 | capillary endothelium | capillary endothelial cell | CL:0002144 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | CD31 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | PMID:2618659 | https://doi.org/10.1111/j.1440-1827.1989.tb02421.x | PMID:12969318 | https://doi.org/10.1034/j.1600-065x.2003.00072.x | |||||||||||||||||||||||||||||||||||||||||||||||
29 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lamina propria | lamina propria of mucosa of colon | UBERON:0007177 | lymphatic endothelium | endothelial cell of lymphatic vessel | CL:0002138 | CD31 | PECAM1 | HGNC:8823 | podoplanin | HGNC:29602 | CD31 | HGNC:8823 | podoplanin | HGNC:29602 | PMID:2618659 | https://doi.org/10.1111/j.1440-1827.1989.tb02421.x | PMID:12969318 | https://doi.org/10.1034/j.1600-065x.2003.00072.x | |||||||||||||||||||||||||||||||||||||||||||||||||||
30 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lamina propria | lamina propria of mucosa of colon | UBERON:0007177 | pericyte | pericyte | CL:0000669 | PDGFRB | HGNC:8804 | PDGFRB | HGNC:8804 | PMID:2618659 | https://doi.org/10.1111/j.1440-1827.1989.tb02421.x | PMID:12969318 | https://doi.org/10.1034/j.1600-065x.2003.00072.x | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
31 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lamina propria | lamina propria of mucosa of colon | UBERON:0007177 | myofibroblast | myofibroblast cell | CL:0000186 | aSMA | HGNC:130 | aSMA | HGNC:130 | PMID:2618659 | https://doi.org/10.1111/j.1440-1827.1989.tb02421.x | PMID:12969318 | https://doi.org/10.1034/j.1600-065x.2003.00072.x | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
32 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lamina propria | lamina propria of mucosa of colon | UBERON:0007177 | fibroblast | fibroblast | CL:0000057 | Col6A1 | HGNC:2211 | Col6A2 | HGNC:2212 | Col6A1 | HGNC:2211 | Col6A2 | HGNC:2212 | PMID:2618659 | https://doi.org/10.1111/j.1440-1827.1989.tb02421.x | PMID:12969318 | https://doi.org/10.1034/j.1600-065x.2003.00072.x | ||||||||||||||||||||||||||||||||||||||||||||||||||||
33 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lamina propria | lamina propria of mucosa of colon | UBERON:0007177 | nerve/schwann cell | Schwann cell | CL:0002573 | S100 | HGNC:1050 | CD56 | HGNC:7656 | PGP9.5 | HGNC:12513 | CD274/PDL1 | HGNC:1050 | CD56 | HGNC:7656 | PGP9.5 | HGNC:12513 | PMID:2618659 | https://doi.org/10.1111/j.1440-1827.1989.tb02421.x | PMID:12969318 | https://doi.org/10.1034/j.1600-065x.2003.00072.x | ||||||||||||||||||||||||||||||||||||||||||||||||
34 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lamina propria | lamina propria of mucosa of colon | UBERON:0007177 | ganglion | peripherin | HGNC:9461 | MAP-2 | HGNC:6839 | peripherin | HGNC:9461 | MAP-2 | HGNC:6839 | PMID:2618659 | https://doi.org/10.1111/j.1440-1827.1989.tb02421.x | PMID:12969318 | https://doi.org/10.1034/j.1600-065x.2003.00072.x | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
35 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | lamina propria | lamina propria of mucosa of colon | UBERON:0007177 | neuroendocrine cell | neuroendocrine cell | CL:0000165 | chromogranin A | HGNC:1929 | synaptophysin | HGNC:11506 | INSM1 | HGNC:6090 | chromogranin A | HGNC:1929 | synaptophysin | HGNC:11506 | INSM1 | HGNC:6090 | PMID:2618659 | https://doi.org/10.1111/j.1440-1827.1989.tb02421.x | PMID:12969318 | https://doi.org/10.1034/j.1600-065x.2003.00072.x | ||||||||||||||||||||||||||||||||||||||||||||||||
36 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | M cell | M cell of gut | CL:0000682 | sialyl lewis a antigen | PMID:9916113 PMCID:PMC96409 | https://doi.org/10.1128/IAI.67.2.946-953.1999 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
37 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | B cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD21 | HGNC:2336 | CD19 | HGNC:1633 | CD20 | HGNC:7315 | CD79a | HGNC:1698 | CD21 | HGNC:2336 | CD19 | HGNC:1633 | CD20 | HGNC:7315 | CD79a | HGNC:1698 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||
38 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | CD4+ T cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | CD3-TCR | HGNC:1673 | CD4 | HGNC:1678 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | TCR alpha/beta | HGNC:1673 | CD4 | HGNC:1678 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||
39 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | regulatory CD4+ T cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD4 | HGNC:1678 | FOXP3 | HGNC:6106 | CD25 | HGNC:6008 | CD4 | HGNC:1678 | FOXP3 | HGNC:6106 | CD25 | HGNC:6008 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||||||
40 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | CD8+ T cell | macrophage | CL:0009018 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | CD3-TCR | HGNC:1673 | CD8 | HGNC:1706 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | TCR alpha/beta | HGNC:1673 | CD8 | HGNC:1706 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||
41 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | macrophage | macrophage | CL:0000235 | HLA-DR | HGNC:1697 | CD163 | HGNC:1631 | CD206 | HGNC:7228 | CD11b | HGNC:6149 | CD68 | HGNC:1693 | HLA-DR | HGNC:1697 | CD163 | HGNC:1631 | CD206 | HGNC:7228 | CD11B | HGNC:6149 | CD68 | HGNC:1693 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||
42 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | NK cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD56 | HGNC:7656 | CD57 | HGNC:921 | CD11c | HGNC:6152 | NKG2D | HGNC:18788 | CD56 | HGNC:7656 | CD57 | HGNC:1695 | CD11c | HGNC:6152 | NKG2D | HGNC:18788 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||
43 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | ILF lymphatic endothelium | endothelial cell of lymphatic vessel | CL:0002138 | LYVE-1 | HGNC:14687 | LYVE-1 | HGNC:14687 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
44 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | ILV high endothelial venule endothelium | endothelial cell of high endothelial venule | CL:0002652 | MADCAM1 | HGNC:6765 | MADCAM1 | HGNC:6765 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
45 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/lamina propria | gut-associated lymphoid tissue | UBERON:0001962 | B cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD21 | HGNC:2336 | CD19 | HGNC:1633 | CD20 | HGNC:7315 | CD79a | HGNC:1698 | CD21 | HGNC:2336 | CD19 | HGNC:1633 | CD20 | HGNC:7315 | CD79a | HGNC:1698 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||
46 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/lamina propria | gut-associated lymphoid tissue | UBERON:0001962 | plasma cell | plasma cell | CL:0000786 | CD138 | HGNC:10658 | CD138 | HGNC:10658 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
47 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/lamina propria | gut-associated lymphoid tissue | UBERON:0001962 | CD4+ T cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | CD3-TCR | HGNC:1673 | CD4 | HGNC:1678 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | TCR alpha/beta | HGNC:1673 | CD4 | HGNC:1678 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||
48 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/lamina propria | gut-associated lymphoid tissue | UBERON:0001962 | regulatory CD4+ T cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD4 | HGNC:1678 | FOXP3 | HGNC:6106 | CD25 | HGNC:6008 | CD4 | HGNC:1678 | FOXP3 | HGNC:6106 | CD25 | HGNC:6008 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||||||
49 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/lamina propria | gut-associated lymphoid tissue | UBERON:0001962 | CD8+ T cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | CD3-TCR | HGNC:1673 | CD8 | HGNC:1706 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | TCR alpha/beta | HGNC:1673 | CD8 | HGNC:1706 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||
50 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/lamina propria | gut-associated lymphoid tissue | UBERON:0001962 | macrophage | macrophage | CL:0000235 | HLA-DR | HGNC:1697 | CD163 | HGNC:1631 | CD206 | HGNC:7228 | CD11b | HGNC:6149 | CD68 | HGNC:1693 | HLA-DR | HGNC:1697 | CD163 | HGNC:1631 | CD206 | HGNC:7228 | CD11b | HGNC:6149 | CD68 | HGNC:1693 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||
51 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/lamina propria | gut-associated lymphoid tissue | UBERON:0001962 | eosinophil | mature eosinophil | CL:0000041 | CD11b | HGNC:6149 | CD294 | HGNC:4502 | CD11b | HGNC:6149 | CD294 | HGNC:4502 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
52 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/lamina propria | gut-associated lymphoid tissue | UBERON:0001962 | mast cell | mast cell | CL:0000097 | CD117 | HGNC:6342 | MCT | HGNC:10922 | CD117 | HGNC:6342 | MCT | HGNC:10922 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
53 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/lamina propria | gut-associated lymphoid tissue | UBERON:0001962 | neutrophil (normally intravascular only) | mature neutrophil | CL:0000096 | CD15 | HGNC:4015 | CD16 | HGNC:3619 | CD15 | HGNC:4015 | CD16 | HGNC:3619 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
54 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/lamina propria | gut-associated lymphoid tissue | UBERON:0001962 | NK cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD56 | HGNC:7656 | CD57 | HGNC:921 | CD11c | HGNC:6152 | NKG2D | HGNC:18788 | CD56 | HGNC:7656 | CD57 | HGNC:921 | CD11c | HGNC:6152 | NKG2D | HGNC:18788 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||
55 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/lamina propria | gut-associated lymphoid tissue | UBERON:0001962 | dendritic cell | dendritic cell | CL:0000451 | HLA-DR | HGNC:1697 | CD11c | HGNC:6152 | CD123 | HGNC:6012 | HLA-DR | HGNC:1697 | CD11c | HGNC:6152 | CD123 | HGNC:6012 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||||||
56 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | mucosa | colonic mucosa | UBERON:0000317 | gut associated lymphoid tissue (GALT)/lamina propria | gut-associated lymphoid tissue | UBERON:0001962 | innate lymphoid cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD127 | HGNC:6024 | CD117 | HGNC:6342 | CD161 | HGNC:6373 | CD127 | HGNC:6024 | CD117 | HGNC:6342 | CD161 | HGNC:6373 | PMID:32160523 PMCID:PMC7155934 | https://doi.org/10.1016/j.immuni.2020.02.001 | ||||||||||||||||||||||||||||||||||||||||||||||||||
57 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis mucosa | muscularis mucosae of colon | UBERON:0007178 | muscularis mucosa | muscularis mucosae of colon | UBERON:0007178 | fibroblast | fibroblast | CL:0000057 | Col6A1 | HGNC:2211 | Col6A2 | HGNC:2212 | Col6A1 | HGNC:2211 | Col6A2 | HGNC:2212 | ISBN-13: 978-1496398949 | ISBN:978-1496398949 | page 652 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
58 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis mucosa | muscularis mucosae of colon | UBERON:0007178 | muscularis mucosa | muscularis mucosae of colon | UBERON:0007178 | nerve | Schwann cell | CL:0002573 | PDL1 | HGNC:17635 | CD56 | HGNC:7656 | PGP9.5 | HGNC:12513 | PDL1 | HGNC:17635 | CD56 | HGNC:7656 | PGP9.5 | HGNC:12513 | ISBN-13: 978-1496398949 | ISBN:978-1496398949 | page 652 | |||||||||||||||||||||||||||||||||||||||||||||||||
59 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis mucosa | muscularis mucosae of colon | UBERON:0007178 | muscularis mucosa | muscularis mucosae of colon | UBERON:0007178 | capillary endothelium | capillary endothelial cell | CL:0002144 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | ISBN-13: 978-1496398949 | ISBN:978-1496398949 | page 652 | |||||||||||||||||||||||||||||||||||||||||||||||
60 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis mucosa | muscularis mucosae of colon | UBERON:0007178 | muscularis mucosa | muscularis mucosae of colon | UBERON:0007178 | lymphatic endothelium | endothelial cell of lymphatic vessel | CL:0002138 | CD31 | PECAM1 | HGNC:8823 | podoplanin | HGNC:29602 | CD31 | PECAM1 | HGNC:8823 | podoplanin | HGNC:29602 | ISBN-13: 978-1496398949 | ISBN:978-1496398949 | page 652 | |||||||||||||||||||||||||||||||||||||||||||||||||||
61 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis mucosa | muscularis mucosae of colon | UBERON:0007178 | muscularis mucosa | muscularis mucosae of colon | UBERON:0007178 | pericyte | pericyte | CL:0000669 | PDGFRB | HGNC:8804 | PDGFRB | HGNC:8804 | ISBN-13: 978-1496398949 | ISBN:978-1496398949 | page 652 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
62 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosa | submucosa of colon | UBERON:0003331 | adipocyte | fat cell | CL:0000136 | S100 | HGNC:1050 | S100 | HGNC:1050 | ISBN-13: 978-1496398949 | ISBN:978-1496398949 | pages 652-653 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
63 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosa | submucosa of colon | UBERON:0003331 | fibroblast | fibroblast | CL:0000057 | Col6A1 | HGNC:2211 | Col6A2 | HGNC:2212 | Col6A1 | HGNC:2211 | Col6A2 | HGNC:2212 | ISBN-13: 978-1496398949 | ISBN:978-1496398949 | pages 652-653 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
64 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosa | submucosa of colon | UBERON:0003331 | nerve | Schwann cell | CL:0002573 | S100 | HGNC:1050 | SOX10 | HGNC:1119 | PGP9.5 | HGNC:12513 | S100 | HGNC:1050 | SOX10 | HGNC:1119 | PGP9.5 | HGNC:12513 | ISBN-13: 978-1496398949 | ISBN:978-1496398949 | pages 652-653 | |||||||||||||||||||||||||||||||||||||||||||||||||
65 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosa | submucosa of colon | UBERON:0003331 | arteriole endothelium | endothelial cell of arteriole | CL:1000412 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | ISBN-13: 978-1496398949 | ISBN:978-1496398949 | pages 652-653 | |||||||||||||||||||||||||||||||||||||||||||||||
66 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosa | submucosa of colon | UBERON:0003331 | venule endothelium | endothelial cell of venule | CL:1000414 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | ISBN-13: 978-1496398949 | ISBN:978-1496398949 | pages 652-653 | |||||||||||||||||||||||||||||||||||||||||||||||
67 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosa | submucosa of colon | UBERON:0003331 | lymphatic endothelium | endothelial cell of lymphatic vessel | CL:0002138 | CD31 | PECAM1 | HGNC:8823 | podoplanin | HGNC:29602 | CD31 | PECAM1 | HGNC:8823 | podoplanin | HGNC:29602 | ISBN-13: 978-1496398949 | ISBN:978-1496398949 | pages 652-653 | |||||||||||||||||||||||||||||||||||||||||||||||||||
68 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosa | submucosa of colon | UBERON:0003331 | capillary endothelium | capillary endothelial cell | CL:0002144 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | PMID:2618659 | https://doi.org/10.1111/j.1440-1827.1989.tb02421.x | PMID:12969318 | https://doi.org/10.1034/j.1600-065x.2003.00072.x | ||||||||||||||||||||||||||||||||||||||||||||||
69 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosa | submucosa of colon | UBERON:0003331 | pericyte | pericyte | CL:0000669 | PDGFRB | HGNC:8804 | PDGFRB | HGNC:8804 | ISBN-13: 978-1496398949 | ISBN:978-1496398949 | pages 652-653 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
70 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | gut associated lymphoid tissue (GALT) and isolated lymphoid follicles (ILF) are 2 independent parts and should be separated; they are not the same. | CD4+ T cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | CD4 | HGNC:1678 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | CD4 | HGNC:1678 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | |||||||||||||||||||||||||||||||||||||||||
71 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | gut associated lymphoid tissue (GALT) and isolated lymphoid follicles (ILF) are 2 independent parts and should be separated; they are not the same. | regulatory CD4+ T cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD4 | HGNC:1678 | FOXP3 | HGNC:6106 | CD25 | HGNC:6008 | CD4 | HGNC:1678 | FOXP3 | HGNC:6106 | CD25 | HGNC:6008 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | |||||||||||||||||||||||||||||||||||||||||||||||||
72 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | gut associated lymphoid tissue (GALT) and isolated lymphoid follicles (ILF) are 2 independent parts and should be separated; they are not the same. | CD8+ T cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | CD3-TCR | HGNC:1673 | CD8 | HGNC:1706 | CD3 | HGNC:1676 | CD7 | HGNC:1695 | CD2 | HGNC:1639 | CD5 | HGNC:1685 | TCR alpha/beta | HGNC:1673 | CD8 | HGNC:1706 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | |||||||||||||||||||||||||||||||||||||
73 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | gut associated lymphoid tissue (GALT) and isolated lymphoid follicles (ILF) are 2 independent parts and should be separated; they are not the same. | macrophage | macrophage | CL:0000235 | HLA-DR | HGNC:1697 | CD163 | HGNC:1631 | CD206 | HGNC:7228 | CD11b | HGNC:6149 | CD68 | HGNC:1693 | HLA-DR | HGNC:1697 | CD163 | HGNC:1631 | CD206 | HGNC:7228 | CD11b | HGNC:6149 | CD68 | HGNC:1693 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | |||||||||||||||||||||||||||||||||||||||||
74 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | gut associated lymphoid tissue (GALT) and isolated lymphoid follicles (ILF) are 2 independent parts and should be separated; they are not the same. | NK cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD56 | HGNC:7656 | CD57 | HGNC:921 | CD11c | HGNC:6152 | NKG2D | HGNC:18788 | CD56 | HGNC:7656 | CD57 | HGNC:921 | CD11c | HGNC:6152 | NKG2D | HGNC:18788 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | |||||||||||||||||||||||||||||||||||||||||||||
75 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | gut associated lymphoid tissue (GALT) and isolated lymphoid follicles (ILF) are 2 independent parts and should be separated; they are not the same. | dendritic cell | dendritic cell | CL:0000451 | HLA-DR | HGNC:1697 | CD11c | HGNC:6152 | CD123 | HGNC:6012 | HLA-DR | HGNC:1697 | CD11c | HGNC:6152 | CD123 | HGNC:6012 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | |||||||||||||||||||||||||||||||||||||||||||||||||
76 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | gut associated lymphoid tissue (GALT) and isolated lymphoid follicles (ILF) are 2 independent parts and should be separated; they are not the same. | ILF lymphatic endothelium | endothelial cell of lymphatic vessel | CL:0002138 | LYVE-1 | HGNC:14687 | LYVE-1 | HGNC:14687 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
77 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | gut associated lymphoid tissue (GALT) and isolated lymphoid follicles (ILF) are 2 independent parts and should be separated; they are not the same. | ILV high endothelial venule endothelium | endothelial cell of high endothelial venule | CL:0002652 | MADCAM1 | HGNC:6765 | MADCAM1 | HGNC:6765 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
78 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | gut associated lymphoid tissue (GALT) and isolated lymphoid follicles (ILF) are 2 independent parts and should be separated; they are not the same. | pericyte | pericyte | CL:0000669 | PDGFRB | HGNC:8804 | PDGFRB | HGNC:8804 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
79 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | gut associated lymphoid tissue (GALT) and isolated lymphoid follicles (ILF) are 2 independent parts and should be separated; they are not the same. | M cell | M cell of gut | CL:0000682 | sialyl lewis a antigen | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
80 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | gut associated lymphoid tissue (GALT)/Isolated lymphoid follicles (ILF) | gut-associated lymphoid tissue | UBERON:0001962 | gut associated lymphoid tissue (GALT) and isolated lymphoid follicles (ILF) are 2 independent parts and should be separated; they are not the same. | B cell | lymphocyte of large intestine lamina propria | CL:0009018 | CD21 | HGNC:2336 | CD19 | HGNC:1633 | CD20 | HGNC:7315 | CD79a | HGNC:1698 | CD21 | HGNC:2336 | CD19 | HGNC:1633 | CD20 | HGNC:7315 | CD79a | HGNC:1698 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | |||||||||||||||||||||||||||||||||||||||||||||
81 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosal plexus of Meissner | submucous nerve plexus | UBERON:0005304 | nerve | Schwann cell | CL:0002573 | S100 | HGNC:1050 | SOX10 | HGNC:1119 | PGP9.5 | HGNC:12513 | S100 | HGNC:1050 | SOX10 | HGNC:1119 | PGP9.5 | HGNC:12513 | PMID:2621148 PMCID:PMC1256735 | PMCID:PMC1256735 | ||||||||||||||||||||||||||||||||||||||||||||||||||
82 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosal plexus of Meissner | submucous nerve plexus | UBERON:0005304 | ganglion | peripherin | HGNC:9461 | MAP-2 | HGNC:6839 | peripherin | HGNC:9461 | MAP-2 | HGNC:6839 | PMID:2621148 PMCID:PMC1256735 | PMCID:PMC1256735 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
83 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | intermediate layer | submucous nerve plexus | UBERON:0005304 | nerve | Schwann cell | CL:0002573 | S100 | HGNC:1050 | SOX10 | HGNC:1119 | PGP9.5 | HGNC:12513 | S100 | HGNC:1050 | SOX10 | HGNC:1119 | PGP9.5 | HGNC:12513 | PMID:2621148 PMCID:PMC1256735 | PMCID:PMC1256735 | ||||||||||||||||||||||||||||||||||||||||||||||||||
84 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | intermediate layer | submucous nerve plexus | UBERON:0005304 | ganglion | peripherin | HGNC:9461 | MAP-2 | HGNC:6839 | peripherin | HGNC:9461 | MAP-2 | HGNC:6839 | PMID:2621148 PMCID:PMC1256735 | PMCID:PMC1256735 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
85 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosal plexus of Henle | submucous nerve plexus | UBERON:0005304 | nerve | Schwann cell | CL:0002573 | S100 | HGNC:1050 | SOX10 | HGNC:1119 | PGP9.5 | HGNC:12513 | S100 | HGNC:1050 | SOX10 | HGNC:1119 | PGP9.5 | HGNC:12513 | PMID:2621148 PMCID:PMC1256735 | PMCID:PMC1256735 | ||||||||||||||||||||||||||||||||||||||||||||||||||
86 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosal plexus of Henle | submucous nerve plexus | UBERON:0005304 | ganglion | peripherin | HGNC:9461 | MAP-2 | HGNC:6839 | peripherin | HGNC:9461 | MAP-2 | HGNC:6839 | PMID:2621148 PMCID:PMC1256735 | PMCID:PMC1256735 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
87 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | submucosa | submucosa of colon | UBERON:0003331 | submucosa | submucosa of colon | UBERON:0003331 | interstitial cell of Cajal | interstitial cell of Cajal | CL:0002088 | CD117 | HGNC:6342 | CD34 | HGNC:1662 | CD117 | HGNC:6342 | CD34 | HGNC:1662 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | PMID:22421617 PMCID:PMC3362097 | https://doi.org/10.1152/ajpgi.00432.2011 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
88 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | circular muscle layer | large intestine smooth muscle circular layer | UBERON:0012398 | muscle | smooth muscle cell of large intestine | CL:1000279 | aSMA | HGNC:130 | smoothelin | HGNC:11126 | aSMA | HGNC:130 | smoothelin | HGNC:11126 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
89 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | circular muscle layer | large intestine smooth muscle circular layer | UBERON:0012398 | fibroblast | fibroblast | CL:0000057 | Col6A1 | HGNC:2211 | Col6A2 | HGNC:2212 | Col6A1 | HGNC:2211 | Col6A2 | HGNC:2212 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
90 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | circular muscle layer | large intestine smooth muscle circular layer | UBERON:0012398 | nerve | Schwann cell | CL:0002573 | S100 | HGNC:1050 | SOX10 | HGNC:1119 | PGP9.5 | HGNC:12513 | S100 | HGNC:1050 | SOX10 | HGNC:1119 | PGP9.5 | HGNC:12513 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
91 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | circular muscle layer | large intestine smooth muscle circular layer | UBERON:0012398 | arteriole endothelium | endothelial cell of arteriole | CL:1000412 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||
92 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | circular muscle layer | large intestine smooth muscle circular layer | UBERON:0012398 | venule endothelium | endothelial cell of venule | CL:1000414 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||
93 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | circular muscle layer | large intestine smooth muscle circular layer | UBERON:0012398 | lymphatic endothelium | endothelial cell of lymphatic vessel | CL:0002138 | CD31 | PECAM1 | HGNC:8823 | podoplanin | HGNC:29602 | CD31 | PECAM1 | HGNC:8823 | podoplanin | HGNC:29602 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
94 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | circular muscle layer | large intestine smooth muscle circular layer | UBERON:0012398 | pericyte | pericyte | CL:0000669 | PDGFRB | HGNC:8804 | PDGFRB | HGNC:8804 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
95 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | myenteric plexus of Auerbach | myenteric nerve plexus | UBERON:0002439 | interstitial cell of Cajal | interstitial cell of Cajal | CL:0002088 | CD117 | HGNC:6342 | CD34 | HGNC:1662 | CD117 | HGNC:6342 | CD34 | HGNC:1662 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
96 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | myenteric plexus of Auerbach | myenteric nerve plexus | UBERON:0002439 | ganglion | peripherin | HGNC:9461 | MAP-2 | HGNC:6839 | peripherin | HGNC:9461 | MAP-2 | HGNC:6839 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
97 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | myenteric plexus of Auerbach | myenteric nerve plexus | UBERON:0002439 | nerve | Schwann cell | CL:0002573 | S100 | HGNC:1050 | SOX10 | HGNC:1119 | PGP9.5 | HGNC:12513 | S100 | HGNC:1050 | SOX10 | HGNC:1119 | PGP9.5 | HGNC:12513 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
98 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | myenteric plexus of Auerbach | myenteric nerve plexus | UBERON:0002439 | fibroblast | fibroblast | CL:0000057 | Col6A1 | HGNC:2211 | Col6A2 | HGNC:2212 | Col6A1 | HGNC:2211 | Col6A2 | HGNC:2212 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
99 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | myenteric plexus of Auerbach | myenteric nerve plexus | UBERON:0002439 | arteriole endothelium | endothelial cell of arteriole | CL:1000412 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||
100 | large intestine | large intestine | UBERON:0000059 | ileocecal valve | ileocecal valve | UBERON:0000569 | muscularis propria | muscle layer of colon | UBERON:0012489 | myenteric plexus of Auerbach | myenteric nerve plexus | UBERON:0002439 | venule endothelium | endothelial cell of venule | CL:1000414 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | CD31 | PECAM1 | HGNC:8823 | CD34 | HGNC:1662 | CD36 | HGNC:1663 | PMID:24997029 | https://doi.org/10.1007/978-1-4939-0897-4_3 | ||||||||||||||||||||||||||||||||||||||||||||||||