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Only speaker is shown in the schedule. The full list of authors is available in the conference proceedings.
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Monday, July 4
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Novosibirsk State University, block 3
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10:00 - 12:00Registration, NSU (on the street in front of the entrance to block 3)
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12:00 - 12:45Conference opening, Room 3307
Nikolay Kolchanov, Academic Advisor of Institute of Cytology and Genetics of SB RAS, Novosibirsk, Russia
Mikhail Fedoruk, Rector of Novosibirsk State University, Novosibirsk, Russia
Ralf Hofestädt, Professor of University of Bielefeld
Alexey Kochetov, Director of Institute of Cytology and Genetics of SB RAS, Novosibirsk, Russia
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Plenary session of the BGRS/SB-2022 conference, Room 3307
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chairman: Andrey Palyanov, Director of A.P. Ershov Institute of Informatics Systems, Novosibirsk, Russia
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12:45 - 13:25Vadim Stepanov
Tomsk National Research Medical Center of the RAS, Tomsk, Russia		Human genomics and evolutionary medicine
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13:25 - 14:05Matteo Barberis
University of Surrey, Guildford, United Kingdom		A novel and robust molecular switch actuating the quantitative model of eukaryotic cdk control
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14:05 - 14:45Ivan Kulakovskiy
Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology of RAS, Moscow; Institute of Protein Research of RAS, Pushchino; Vavilov Institute of General Genetics of RAS, Moscow, Russia		Interpreting non-coding genome variation with DNA sequence motifs
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14:45 - 15:05Coffee break
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chairman: Roman Efremov, Deputy sci-director of Shemyakin-Ovchinnikov Institute of bioorganic chemistry, Moscow, Russia
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15:05 - 15:45Vladimir Popov
Federal Research Centre "Fundamentals of Biotechnology" of the RAS, Moscow, Russia		From 3D protein structure to biological function
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15:45 - 16:25Yan Zubavichus
Boreskov Institute of Catalysis of SB RAS, Novosibirsk; Synchrotron Radiation Facility SKIF, Koltsovo, Russia		4th Generation Synchrotron Radiation Facility SKIF: New Prospects for High-Throughput Macromolecular Crystallography in Russia
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16:25 - 17:05Vadim Govorun
Scientific Research Institute for Systems Biology and Medicine, Moscow, Russia		Some questions of synthetic biology
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17:05 - 17:20Tatyana Sulgina
DIA-M
www.dia-m.ru
3D-Tomography without Tomographic Equipment. Bioluminescence and Fluorescence In Vivo Imaging System Newton 7.0 (Vilber)
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17:20 - 17:40Coffee break
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chairman: Vladimir Poroikov, Head of Department of Institute of Biomedical Chemistry, Moscow, Russia
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17:40 - 18:20Valery Danilenko
Vavilov Institute of General Genetics, RAS, Moscow, Russia		Study of human and animal microbiome as genetic and pharmacological resources for the development of innovative biotechnologies for medicine, animal husbandry and agro-industrial complex
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18:20 - 19:00Eric Bishop von Wettberg
The University of Vermont, Vermont, USA		The need to study biodiversity: the case of crop wild relatives
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Tuesday, July 5
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Poster session: block 3, floor 3
09:00 - 10:00
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Room 3307Room 3312Room 3313Room 3318Room 4310
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Morning session
10:00 - 13:00
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SYMPOSIUM 1: "Genomics, transcriptomics and bioinformatics"

Symposium keynote lectures
chairs: Dmitry Afonnikov, Veniamin Fishman		SYMPOSIUM 2: "Systems computational biology"

Symposium keynote lectures
chairs: Efim Frisman, Sergey Lashin		SYMPOSIUM 7: "Animal genetics, bioinformatics and systems computational biology"

Section "Neurogenomics and genetics of Behavior"
chairs: Vladimir Naumenko		SYMPOSIUM 3: "Structural biology and pharmacology: computational and experimental approaches"

Symposium keynote lectures
chairs: Roman Efremov, Vladimir Poroikov		SYMPOSIUM 8: "Biomedicine, bioinformatics and systems biology"

Symposium keynote lectures
chairs: Andrei Letyagin, Maxim Korolev
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Keynote lecture:
Maps of chromatin conformation in
the cerebral cortex
Ekaterina Khrameeva
Skolkovo Institute of Science and Technology, Moscow, Russia
10:00 - 10:40		Keynote lecture:
On organizing a software platform for seeking biotechnologically important features in bacteria
Sergey Lashin
Kurchatov Genomics Center of the Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia;
Novosibirsk State University, Novosibirsk, Russia
10:00 - 10:40		Keynote lecture:
Novel approaches for analysis of the functional activity of neural networks in vitro
Maria Vedunova
Institute of Biology and Biomedicine, National Research Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, Russia
10:00 - 10:40		Keynote lecture:
Structural basis of TRP channel temperature sensitivity
Alexander Sobolevsky
Columbia University Irving Medical Center
New York, United States
10:00 - 10:40		Keynote lecture:
Artificial intelligence (AI) of 3D MRI Images for neurooncology
Andrey Letyagin
Novosibirsk State University, Novosibirsk, Russia;
Instutute of Clinical and Experimental Lymphology - branch of ICG SB RAS
10:00 - 10:40
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Keynote lecture:
Origin of the auxin biosynthesis pathway in land plants in the light of evolution of TAA and YUCCA genes
Dmitry Afonnikov
Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia;
Kurchatov Genomic Center of the Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
Novosibirsk State University, Novosibirsk, Russia
10:40 - 11:20		Keynote lecture:
Evolutionary development of mathematical models of complex biological systems
Fedor Kolpakov
Sirius University, Sochi, Russia
FRC for Information and Computational Technologies, Novosibirsk, Russia
BIOSOFT.RU, Ltd, Novosibirsk, Russia
10:40 - 11:20

Effects of the original synthetic ligand of benzodiazepine receptors in long-term alcoholized mice
Ivan Savkin
Federal State Budgetary Scientific Institution “Research Institute of Fundamental and Clinical Immunology”, Laboratory of Neuroimmunology, Novosibirsk, Russia
10:40 - 11:00		Keynote lecture:
”Dynamic molecular portraits” of biomembranes: a computational insight
Roman Efremov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Russia
Moscow Institute of Physics and Technology, Dolgoprudny, Russia
National Research University Higher School of Economics, Moscow, Russia
10:40 - 11:20		Keynote lecture:
DNA Aptamers for Diagnosis and Treatment of Human Diseases
Mariya Vorobyeva
Institute of Chemical Biology and Fundamental Medicine, SB RAS, Novosibirsk, Russia
10:40 - 11:20
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Nanoparticle axonal transport assessment in neurodegeneration susceptible mice strain
Daniil Zuev
Novosibirsk State University, Novosibirsk, Russia
11:00 - 11:20
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Coffee break
11:20 - 11:40
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SYMPOSIUM 1: "Genomics, transcriptomics and bioinformatics"

Symposium keynote lectures
chairs: Dmitry Afonnikov, Ivan Kulakovskiy		SYMPOSIUM 2: "Systems computational biology"

Symposium keynote lectures
chairs: Efim Frisman, Sergey Lashin		SYMPOSIUM 7: "Animal genetics, bioinformatics and systems computational biology"

Section "Neurogenomics and genetics of Behavior"
chairs: Vladimir Naumenko, Tamara Amstislavskaya		SYMPOSIUM 3: "Structural biology and pharmacology: computational and experimental approaches"

Symposium keynote lectures
chairs: Roman Efremov, Vladimir Poroikov		SYMPOSIUM 8: "Biomedicine, bioinformatics and systems biology"

Symposium keynote lectures
chairs: Andrei Letyagin, Maxim Korolev
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Keynote lecture:
Transcriptomics as an effective tool to study plant cell wall formation and function
Tatiana Gorshkova
Kazan Institute of Biochemistry and Biophysics, FRC KazRC RAS, Kazan, Russia
11:40 - 12:20		Keynote lecture:
Alpine resort or battle for survival: A didactic story about short-lived perennials and their matrix models
Dmitrii Logofet
A.M. Obukhov Institute of Atmospheric Physics, RAS, Moscow, Russia
11:40 - 12:20		Effects of amisulpride on the Tau-protein hyperphosphorilation in OXYS rats: a model of sporadic Alzheimer's disease
Vladimir Naumenko
Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
11:40 - 12:00		Keynote lecture:
Drug repurposing for COVID-19 therapy: challenges and opportunities
Vladimir Poroikov
Institute of Biomedical Chemistry, Moscow, Russia
11:40 - 12:20
Keynote lecture:
The problem of immunological tolerance in the pathogenesis of autoimmune diseases
Tamara Tyrinova
Scientific Research Institute of Clinical immunology, Siberian Branch, Academy of Medical Sciences of Russia
11:40 - 12:20
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Risk factors for the development of post-stress neuroinflammation: studies on rat strains with contrast excitability of the nervous system
Irina Shalaginova
Immanuel Kant Baltic Federal University, Kaliningrad, Russia
12:00 - 12:20
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Keynote lecture:
Functional annotation of lncRNAs involved in epigenetic regulation in
normal and pathological processes
Yulia Medvedeva
Federal Research Centre "Fundamentals of Biotechnology" of the RAS, Moscow, Russia
12:20 - 13:00		Rearrangements of actin cytoskeleton in atherosclerotic plaque development (experimental study)
Nikolay Sudakov
Limnological Institute, SB RAS, Irkutsk, Russia;
Irkutsk Scientific Centre of Surgery and Traumatology, SB RAS, Irkutsk, Russia
12:20 - 12:35		Keynote lecture:
Nanoteranostics based on multimodal nanoparticles and nanosystems
Irina Zavestovskaya
P.N. Lebedev Physical Institute of RAS, Moscow, Russia;
National Research Nuclear University MEPhI, Moscow, Russia
12:20 - 13:00		Keynote lecture:
Applications of next-generation sequencing for clinical diagnostics of monogenic diseases
Veniamin Fishman
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
12:20 - 13:00
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Neurodegeneration and diabetes: positive effect of trehalose in behavior of db/db mice, model of diabetes
Tatiana Korolenko
Research Institute of Neurosciences and Medicine, Novosibirsk, Russia
12:35 - 12:50
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Colitis-associated intestinal microbiota regulates brain glycine and host behavior in mice
Elena Kozhevnikova
Research Institute of Neurosciences and Medicine, Novosibirsk, Russia
12:50 - 13:05
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Lunch
13:00 - 14:20
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Afternoon session
14:20 - 16:40
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SYMPOSIUM 1: "Genomics, transcriptomics and bioinformatics"

Section "Regulatory genomics"
chairs: Victor Levitsky, Ivan Kulakovskiy		SYMPOSIUM 2: "Systems computational biology"

Section "Reconstruction, computational analysis and modeling of biological systems"
chairs: Sergey Lashin, Matteo Barberis		SYMPOSIUM 7: "Animal genetics, bioinformatics and systems computational biology"

Section "Neurogenomics of Behavior"
chairs: Tamara Amstislavskaya, Vladimir Naumenko		SYMPOSIUM 3: "Structural biology and pharmacology: computational and experimental approaches"

Section "Structural biology of proteins and membranes"
chairs: Roman Efremov, Konstantin Mineev		SYMPOSIUM 8: "Biomedicine, bioinformatics and systems biology"

Section "Gene Expression and Human Diseases"
chairs: Vadim Klimontov, Tatjana Merculova
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Keynote lecture:
GESECA: Gene Set Co-regulation Analysis
Alexey Sergushichev
ITMO University, St. Petersburg, Russia
14:20 - 14:55
Poster session:
block 3, floor 3
14:20 - 15:00		Keynote lecture:
Neurogenomics of zebrafish
Allan Kalueff
Saint-Petersburg State University
Institute of Translational Biomedicine, Saint-Petersburg, Russia
14:20 - 14:55		Structure of Toll-like receptors: the input from solution NMR spectroscopy
Konstantin Mineev
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Russia
14:20 - 14:40		Role of HSP70 proteins in regulation of mitochondrial protein content in skeletal muscle
Daniil Popov
Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Russia;
M.V. Lomonosov Moscow State University, Moscow, Russia
14:20 - 14:40
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Statistical approach to regulation of membrane-permeabilizing activity of antimicrobial peptides
Sergey Akimov
A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, RAS, Moscow, Russia
14:40 - 15:00		Profiling of targeted miRNAs (8-mer) for the genes involved in type 2 diabetes mellitus and cardiac hypertrophy
Iram Murtaza
Signal transduction laboratory, Department of Biochemistry, Quaid-i-Azam University, 45320, Islamabad, Pakistan
14:40 - 15:00
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Keynote lecture:
Web-MCOT server for motifs co-occurrence search in ChIP-seq data
Victor Levitsky
Institute of Cytology and Genetics, Novosibirsk, Russia;
Novosibirsk State University, Novosibirsk, Russia
14:55 - 15:30		Modeling of Neuropathology on Zebrafish: Traumatic Brain Injury
Tamara Amstislavskaya
Novosibirsk State University, Novosibirsk, Russia;
Scientific Research Institute of Neurosciences and Medicine, Novosibirsk, Russia
14:55 - 15:10
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Keynote lecture:
Petri net modeling and simulation of biological networks
Ralf Hofestädt
AG Bioinformatics and Medical Informatics, University Bielefeld, Bielefeld, Germany
15:00 - 15:30		Study of membrane permeability for various peptides by steered molecular dynamics
Oxana Galzitskaya
Institute of Protein Research, Russian Academy of Sciences, Pushchino, Russia;
Institute of Theoretical and Experimental Biophysics Russian Academy of Sciences, Pushchino, Russia
15:00 - 15:20		Transcriptome of failing human heart reveals atrial myocytes reprogramming
Ruslan Deviatiiarov
Regulatory Genomics Research Center, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia
15:00 - 15:20
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Keynote lecture:
Modern models of brain diseases for translational studies
Alla Salmina
Research Center of Neurology, Moscow, Russia
15:10 - 15:40
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Structure and dynamics of REGN10987 Fab interaction with S-proteins of Delta and Omicron SARS-CoV-2 Variants
Zakhar Shenkarev
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow, Russia
15:20 - 15:40		Construction of comprehensive amino acid networks from Molecular Dynamics trajectories and tumor mutational profile of human sodium transporter NaPi2b
Ramilia Vlasenkova
Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia
15:20 - 15:40
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Keynote lecture:
ANDSystem: cognitive computer system for automated gene networks reconstruction and analysis
Vladimir Ivanisenko
Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia;
Kurchatov Genomic Center of the Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia;
Novosibirsk State University, Novosibirsk, Russia
15:30 - 16:00
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enRest tool for transcription factor binding sites overrepresentation analysis in RNA-seq data
Anton Tsukanov
Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
15:30 - 15:50		Psychoneuroimmunomodulating effect of immune cells in depressive-like mice
Evgeniya Markova
Federal State Budgetary Scientific Institution “Research Institute of Fundamental and Clinical Immunology”: Laboratory of Neuroimmunology. Novosibirsk, Russia
15:40 - 15:55
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The insight into structural properties of unique tardigrade radioprotective damage suppressor protein (Dsup)
Mikhail Zarubin
Dzhelepov Laboratory of Nuclear Problems, Joint Institute for Nuclear Research, Dubna, Russia
15:40 - 15:55		The role of insulin receptor signaling in regulation of synaptic glutamatergic hippocampal neurotransmission
Svetlana Vechkapova
Federal Research Center of Information and Computational Technologies, Novosibirsk, Russia
15:40 - 16:00
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Promoter motif inference and annotation of promoter sequences in bacterial genomes based on the analysis of structures of alternative sigma factor-promoter complexes
Dmitry Gromyko
Department of Molecular Biology, Belarusian State University, Minsk, Belarus
15:50 - 16:10		New antiparkinsonian agent Diol restores cognitive function, enhances neurotrophic function, and diminishes neuroinflammation in a MPTP-induced model of Parkinson's disease in mice
Maria Tikhonova
Scientific Research Institute of Neurosciences and Medicine, Novosibirsk, Russia
15:55 - 16:10		Allosteric ligand subpocket of S1P5 as a determinant of inverse agonism and ligand specificity
Elizaveta Lyapina
Research Сenter for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny 141701, Russia
15:55 - 16:10
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Age-related alterations in the mouse liver circadian clock are caused by an imbalance of the NAD + consumption system
Nikolay Podkolodnyy
Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia;
Institute of Computational Mathematics and Mathematical Geophysics, SB
16:00 - 16:20		Sponsor report:
New solutions for medical genetics and biotechnologies from Maxim Medikal LLC
Dmitriy Chemeris
Maxim Medikal LLC
16:00 - 16:20
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Effects of two types of the central (intracerebroventricular vs. intrahippocampal) administration of Aβ25-35 on the induction of Alzheimer’s Disease-like pathology in mice
Victor Belichenko
Scientific Research Institute of Neurosciences and Medicine, Novosibirsk, Russia
16:10 - 16:25		Hierarchical Structure of Protein Sequences – New Insight of Protein Organization
Anastasia Anashkina
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str., 32, 119991 Moscow, Russia
16:10 - 16:25
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Sponsor report:
Application of Capillary Gel Electrophoresis Qsep System in Nucleic Acid Evaluation for NGS-library Preparation
Svetlana Oleynikova
DIA-M
www.dia-m.ru
16:10 - 16:30
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Study of the mechanism of reactions catalyzed by complexes of cytochrome c with cardiolipin
Irina Levchenko
Pirogov Russian National Research Medical University,Moscow,Russia
16:20 - 16:40
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Combined treatment with autophagy inducers rapamycin and trehalose as an experimental therapy for Alzheimer's disease-like pathology in mice
Alim Bashirzade
Scientific Research Institute of Neuroscience and Medicine, Novosibirsk, Russia;
Novosibirsk State University, Novosibirsk, Russia
16:25 - 16:40		Structure and dynamics of the SARS-CoV-2 envelope protein
Alexander Kuzmin
Research Center for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and
Technology, Dolgoprudny, Russia
16:25 - 16:40
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Coffee break
16:40 - 17:00
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Evening session
17:00 - 19:40
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SYMPOSIUM 1: "Genomics, transcriptomics and bioinformatics"

Section "Regulatory genomics"
chairs: Victor Levitsky, Ivan Kulakovskiy		SYMPOSIUM 2: "Systems computational biology"

Section "Reconstruction, computational analysis and modeling of biological systems"
chairs: Sergey Lashin, Matteo Barberis		SYMPOSIUM 7: "Animal genetics, bioinformatics and systems computational biology"

Section "Neurogenomics of Behavior"
chairs: Tamara Amstislavskaya		SYMPOSIUM 3: "Structural biology and pharmacology: computational and experimental approaches"

Section "Structural biology of proteins and membranes"
chairs: Roman Efremov, Ekaterina Lyukmanova		SYMPOSIUM 8: "Biomedicine, bioinformatics and systems biology"

Section "Material Science and Regenerative Medicine"
chairs: Anton Manakhov, Anastasia Solovieva
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Keynote lecture:
New insights on genome organization, RNA expression regulation and evolution of anhydrobiotic insect Polypedilum vanderplanki
Elena Shagimardanova
Regulatory Genomics Research Center, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia
17:00 - 17:35		Data lake platform of the bacterial strain properties for microbiology
Alexey Mukhin
Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia;
Kurchatov Genomics Center of the Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
17:00 - 17:20		Antipsychotic activity of a new PTPN5 blocker (TC-2051) in mice with the Disc1-L100P mutation
Nadezhda Chizhova
Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia;
Federal State Budgetary Scientific Institution “Scientific Research Institute of Neurosciences and Medicine”, Novosibirsk, Russia
17:00 - 17:20
Membrane Environment Regulates Interaction of Three-Finger Toxins with Nicotinic Acetylcholine Receptors
Ekaterina Lyukmanova
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia;
Phystech School of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), Dolgoprudny, Moscow Region, Russia;
Interdisciplinary Scientific and Educational School of Moscow University «Molecular Technologies of the Living Systems and Synthetic Biology», Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia
17:00 - 17:20
Generation of stable breast cancer cell lines with overexpression of αvβ3 integrin
Ekaterina Sukhinina
Siberian State Medical University, Tomsk, Russia;
Tomsk Polytechnic University, Tomsk, Russia
17:00 - 17:20
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Evolutionary analysis of gene networks with Orthoweb software
Zakhar Mustafin
Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia;
Novosibirsk State University, Novosibirsk, Russia
17:20 - 17:40		Effect of chronic unpredictable mild stress on stress resilience in Disc1-Q31L mice
Kristina Smirnova
Scientific research institute of Neuroscience and Medicine, Novosibirsk, Russia;
Novosibirsk state university, Russia
17:20 - 17:40		Structure and dynamics of chromatin at nucleosome level: integrating experiments and simulations
Alexey Shaytan
Department of Biology, Lomonosov Moscow State University, Moscow, Russia
17:20 - 17:40		Ag modification of PLC-COOH nanofibers provides mesenchymal cells proliferation
Natalya Sitnikova
RICEL - Branch of ICG SB RAS, Novosibirsk, Russia
17:20 - 17:40
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