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Dark Matter and EnergyExamining the unknown forces that make up the vast majority of the universe's mass-energy.
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Origin of LifeInvestigating the mechanism behind the emergence of life from non-living matter.
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Consciousness NatureUnderstanding the physical basis of consciousness and how it arises in the brain.
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Room-Temperature Superc.Room-Temperature Superconductivity is about developing a practical and efficient way to conduct electricity with zero resistance.
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God's ExistenceExploring the philosophical and theological question of whether or not a higher power exists.
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Alzheimer's CureDeveloping effective treatments for a debilitating and widespread degenerative brain disorder.
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Nature of TimeUnderstanding the true nature of time and why it seems to move in only one direction.
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Sustainable FusionDeveloping a clean and abundant source of energy through nuclear fusion.
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Cosmic RaysInvestigating the origin and nature of high-energy particles that bombard the Earth from space.
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Earthquake PredictionUnderstanding and predicting earthquakes to mitigate their widespread damage and loss of life.
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Universe's ExtentExploring the vastness of the universe and the possibility of other intelligent life.
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Biodiversity OriginTracing the evolution and diversification of life on Earth from its origins.
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Neurodegenerative Treat.Developing effective treatments for diseases such as Alzheimer's.
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Microbial WorldUnderstanding the true extent and nature of the microbial world and its interactions with other life forms.
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P vs NPCan every problem that can be checked by a computer be solved by a computer in a reasonable amount of time?
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Bronze Age & Pharaonic Cult.The connection between the Bronze Age civilization in the Aegean and the Pharaonic culture in Egypt
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Practical Nuclear FusionAchieving efficient and practical nuclear fusion as a clean source of energy.
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Fate of the UniverseThe possible scenarios for the ultimate fate of the universe, including the Big Crunch and the Big Freeze.
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Complex SystemsThe challenges of predicting the behavior of complex systems, such as the global climate and the human brain.
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Fundamental LawsThe search for the fundamental laws and principles that govern the behavior of matter and energy at the smallest scales.
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Achieving Human-like AIThe challenge of creating artificial intelligence that can truly think, create, and possess consciousness like a human.
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Life's OriginThe scientific inquiry into how life originated on Earth and evolved into its current state.
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Sustainable FusionThe potential of nuclear fusion to provide a limitless source of clean energy and the challenges of achieving it.
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Identity of HomerThe actual identity of Homer
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Yang-Mills and Mass GapDoes the Yang-Mills theory have a mass gap?
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Understanding AgingThe biological processes that lead to aging and age-related diseases and their underlying causes.
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Multiverse TheoryThe debate among physicists about the existence of parallel universes beyond our own.
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Earthquake PredictionThe ongoing challenge of accurately predicting when and where earthquakes will occur.
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Riemann HypothesisAre all non-trivial zeros of the Riemann zeta function located on the critical line?
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Tutankhamun's deathWas Pharaoh Tutankhamun murdered, and why was he carefully embalmed for his next life?
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Knowledge & false premisesA philosophical question on whether something can still be considered knowledge if it was derived from false premises.
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Biological aging processA discussion on why all living things age.
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Extending life expectancyA consideration of how far we can push the limits of human life expectancy.
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Anoxycalyx joubini lifeA look into the extraordinary lifespan of this particular sponge and the reasons for its longevity.
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Aging and dying connectionAn exploration of the relationship between aging and mortality.
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Religion & life expectancyA study on the correlation between religious beliefs and longer life expectancies.
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Moai Statue origin & functionThe origin and function of the Moai statues on Easter Island
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Rock star mortality rateA curious examination of the elevated mortality rate of musicians in the early years of their careers.
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High-dimensional structuresA question on whether high-dimensional figures can be described by polynomial equations.
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Device impact on decisionsAn inquiry into why the characteristics of a third device not even in consideration can impact our decision making when choosing between two options.
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Probability & next sunriseWhat is the statistical probability of the sun rising tomorrow after observing 10,000 sunrises?
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Understanding probabilityWhy is it difficult for individuals to understand if a probability of 99.990002% for the next sunrise is good or bad news, as calculated by Pierre Simon de Laplace?
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Mary Celeste mysteryWhat happened on the two-masted sailing ship "Mary Celeste," which was found drifting without a crew in the Atlantic Ocean in 1872?
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Cleopatra's Tomb locationThe location of Cleopatra's tomb
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MH370 disappearanceWhat happened to the Boeing 777 of Malaysia Airlines Flight 370, which disappeared from air traffic control surveillance on March 8, 2014, at 1:21 am with 239 people on board?
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World populationHow many people currently live on Earth?
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Navier-Stokes EquationsCan the solutions to the Navier-Stokes equations be shown to exist and be smooth?
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Roanoke's truthThe truth behind the disappearance of Roanoke, the 'Lost Colony' in North America
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Earth's sustainabilityCan the Earth sustain a projected population of 11.2 billion in the year 2100, as estimated by the United Nations?
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Protecting democraciesHow can democracies be protected from becoming authoritarian regimes?
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Education & global issuesHow can education enable humanity to solve global problems?
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Cryonics freezingWill American psychology professor James Bedford be revived from cryonic preservation and how can he be thawed without damaging his body cells and organs?
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Universe's fateWill the universe contract in a Big Crunch after the Big Bang or will the sun become a Red Giant, making higher life forms impossible?
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Birch & Swinnerton-DyerCan the rank of elliptic curves be predicted by certain analytic expressions?
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Stonehenge functionThe exact function of Stonehenge
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Maya Civilization CollapseThe cause of the collapse of the Maya civilization
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Pre-Big Bang UniverseThe mystery of what existed before the Big Bang and the origin of the universe itself.
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Achieving true AIThe difficulty of creating a machine that can truly think and reason like a human.
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Chemical origin of lifeHow life emerged from non-life through chemical processes.
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Fate of the UniverseHow the universe will end, including the possibilities of a Big Freeze, Big Crunch, or Big Rip.
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Missing baryonsThe mystery of the missing 5% of the universe's expected baryonic matter.
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The Hubble tensionThe discrepancies between measurements of the expansion rate of the universe.
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Quantum gravityThe theory that seeks to reconcile general relativity with quantum mechanics.
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Nature of timeexploring whether time is an objective feature of the universe or a human construct
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Fermi paradoxinvestigating the question of why we have not yet detected any signs of extraterrestrial intelligence
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Composition of universeexamining the nature and composition of the universe, including dark matter and dark energy
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blue whale matingAn exploration of the elusive mating behavior of blue whales, the largest animals on earth.
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Plate tectonicsunderstanding why Earth has drifting continental plates and whether this phenomenon exists elsewhere
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Origin of lifeexamining how life emerged from non-living matter
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Extraterrestrial lifeinvestigating whether life has arisen elsewhere in the universe
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nature of consciousnessexploring the definition and characteristics of consciousness. investigating whether machines can have consciousness
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Wow signal & messageexploring the origin and meaning of a mysterious radio signal detected in 1977, which includes the code "6EQUJ5"
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Dinosaur colorsinvestigating the coloring of dinosaurs and the reasons for their large size
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Human evolutionexploring the factors that led to the development of human culture and intelligence
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Brain growthconsidering whether a single mutation led to the brain growth that gave humans an evolutionary advantage
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Purpose of Nazca LinesThe purpose of the Nazca lines in Peru
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Consciousness & Genesexamining the relationship between the number of genes and neurons and the development of consciousness
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Sexual reproductionconsidering why sexual reproduction with two sexes has evolved despite reducing evolutionary fitness
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Hodge ConjectureCan the topology of algebraic varieties be determined by algebraic cycles?
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Terracotta ArmyThe significance and purpose of the ancient Terracotta Army in China
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Neanderthal extinctioninvestigating the causes of the demise of the Neanderthals, including their reproductive habits.
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Child development speedA fascinating question on how infants can develop such a wide range of abilities in such a short time.
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Pants on rat matingAn unusual study investigating the impact of clothing material on rat mating behavior and whether it applies to humans.
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P vs NPCan every problem that can be checked by a computer be solved by a computer in a reasonable amount of time?
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