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Use the updated calculator (n=1,201) https://goo.gl/THCnuU
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GIANT CELL ARTERITIS RISK CALCULATOR
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n=530 temporal artery biopsies with 133 events from 7 medical centers
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pseudoR2 =0.256, AUROC =0.819(bootstrap 95%CI 0.757, 0.849), pH-L=0.549, External validation AUROC 0.688-0.824)
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The calculator is used at your physician's discretion. The authors bear NO responsibility for clinical decisions made with this tool.
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INPUT NUMBERS BELOW - PLEASE DO NOT COPY + PASTE
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Age (in years)Observed Probability CUTPOINTFull Model Observed PercentileRisk of GCA (biopsy-proven)
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Gender (1=Female, 0= Male)1Negative biopsyPositive biopsy
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Jaw Claudication (1= Yes, 0=No)12.7%7th<1Very low
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Diplopia (1=Yes, 0=No)17%31st5thLow
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New onset headache (1=Yes, 0=No)114%54th16thIntermediate
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Temporal Artery ropy, pulseless, tender (1=Yes, 0=No)123%75th25thModerate
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Disc Edema / CRAO / PION (1=Yes, 0=No)043%92nd50thHigh
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Platelets2252%95th55thVery high
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C-reactive protein (CRP)2.589%99.9th96thExceedingly high
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Your lab's upper limit of normal of CRP0.4
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ESR (Westergren)
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Probability of Positive Temporal Artery Biopsy#REF!
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*Gender and Diplopia were NOT predictive for GCA in this study
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Title: Multivariable Prediction Model for suspected Giant Cell Arteritis:
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Development and Validation
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Authors: Edsel Ing a
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Gabriela Lahaie Luna b
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Andrew Toren c
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Royce Ing d
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John J. Chen e
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Nitika Arora e2
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Nurhan Torun f
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Otana Jakpor f2
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J. Alexander Fraser g
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Felix Tyndel a2
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Arun Sundaram a2
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Xinyang Liu h
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Cindy T. Y. Lam a
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Vivek Patel i
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Ezekiel Weis j
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David Jordan k
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Steven Gilberg k
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Christian Pagnoux l
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Martin ten Hove b
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a University of Toronto Medical School, Department of Ophthalmology & Vision Sciences, Toronto, ON, Canada
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a2 University of Toronto Medical School, Department of Medicine, Neurology, Toronto, ON, Canada
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b Queens University Department of Ophthalmology, Kingston, ON, Canada
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c University of Laval, Department of Ophthalmology, Quebec, QC, Canada
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d Toronto Eyelid, Strabismus & Orbit Surgery Clinic, Toronto, ON, Canada
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e Mayo Clinic, Department of Ophthalmology & Neurology, Rochester, MN, USA
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e2 Mayo Clinic, Department of Ophthalmology, Rochester, MN, USA
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f Harvard Medical School, Beth Israel Deaconess Hospital, Department of Ophthalmology, Boston, MA, USA
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f2 Harvard Medical School, Boston, MA, USA
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g Western University, Departments of Clinical Neurological Sciences and Ophthalmology, London, ON, Canada
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h Fudan University Shanghai Medical College, Department of Medicine, Shanghai, SH, China
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i University of Southern California, Keck Medicine, Roski Eye Institute, Los Angeles, CA, USA
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j Universities of Alberta and Calgary, Departments of Ophthalmology, Edmonton and Calgary, AB, Canada
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k University of Ottawa, Department of Ophthalmology, Ottawa, ON, Canada
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l Vasculitis Clinic, Mount Sinai Hospital, Toronto, ON, Canada
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Correspondence: Dr. Edsel Ing, Michael Garron Hospital, 650 Sammon Ave, K306, Toronto, ON. M4C 5M5
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Tel 416) 465-7900
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Fax 416) 465-2035
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