ABCDEFGHIJKLMNOPQRSTUVWXY
1
GroupNames Preferred Contact MethodPotential Research Topics/InterestsResearch Question IdeasResearch Question Approved by BOTH Professors? Type your approved question here AFTER is has been approved by both Dr. Lowengrub and Dr. Embler.
2
1Aditya Verma, Daniel Ko, Ian ParkemailTargeted (or untargeted) metabolomics screen using Mass Spectrometry "Identifying biomarkers of breast cancer cells using a targeted metabolomics screen to understand the metabolism of said cells vs normal cells." Biomarkers could include Estrogen Receptor, Progesterone Receptor, HER2.
3
2Eve Hazard, Sylvia Lyu, Emily Ren, Lauren Leeemail1) imaging HUVEC cell tube formation with and without
angiogenesis inhibitors (angiostatin)
2) proliferation of cancerous cells with the use of oncogene
inhibitor or deregulation of signaling pathways, possible
examples: farnesyl transferase inhibitors, dasatinib
4
3
5
4Ann Vu, Anna Ding, Charlize NishitoyoEmail/TextTreating the SW480 cells with advil promoting EMT induction, then using qPCR to detect gene expression for biomarkers (looking for deregulation of E-cadherin, increased N-cadherin expression, and upregulated vimentin).
6
5
7
6Harshitha Palacharla, Allison Huang, Allison TangEmail/TextBiology Lab: Test the effectiveness of ibuprofen in inhibiting the Wnt/beta-catenin pathway in SW480 cells. Conduct a metabolomics anaysis with targeted MS for diacetylspermine (potential cancer biomarker in colorectal cells) in the cultures with and w/out ibuprofen.

Mathematical Model: Cancer cell proliferation with and without addition of inhibitors
8
7
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100