ABCDEFGHIJKLMNOPQRSTUVWX
1
2
Heat map for Drug Candidates
3
(c) Venture Center, Pune, India (2020)
4
Based on Assessment Framework -# 1: IP
5
Owner:Vidula Walimbe
6
Last update:21 April 2020
7
Legend: Yes (1)No(0)
8
9
Do patent barriers exist and how strong are they?
10
Drug candidateThere are valid active patents in India for basic composition/ formulation/ processes (Yes -1; No -0)Basic composition of API is protected in India with valid active patents (Yes -1; No -0)Basic (Innovator's) process of manufacture of API is protected in India with valid active patents (Yes -1; No -0)Basic (Innovator's) formulation/ drug product (not API) is protected in India with valid active patents (Yes -1; No -0)Patent barriers exist? (Yes -1; No -0)Strength of patent barriers (higher% means Higher barriers; weightage for composition is higher)Drug candidate
11
Chloroquine000000%Chloroquine
12
Hydroxychloroquine000000%Hydroxychloroquine
13
Remdesivir11111100%Remdesivir
14
Lopinavir/Ritonavir000000%Lopinavir/Ritonavir
15
Favipiravir1011150%Favipiravir
16
Baloxavir Marboxil11111100%Baloxavir Marboxil
17
Darunavir000000%Darunavir
18
Ribavirin + IFN beta000000%Ribavirin + IFN beta
19
Galidesivir000000%Galidesivir
20
Oseltamivir000000%Oseltamivir
21
Umifenovir000000%Umifenovir
22
Camostat mesylate000000%Camostat mesylate
23
Ruxolitinib11111100%Ruxolitinib
24
Interferon beta000000%Interferon beta
25
Tocilizumab000000%Tocilizumab
26
Ustekinumab11111100%Ustekinumab
27
Nigericin000000%Nigericin
28
Teicoplanin000000%Teicoplanin
29
Ivermectin000000%Ivermectin
30
Source: TFORD-COVID19-India (c) Venture Center, 2020
31
32
Is there a need for Govt action to provide FTO for Indian manufacturers?
33
Drug candidateStrength of Patent barriers exist? Valid active patents are NOT being worked in India (directly or via licensees) (Yes- 1; No-0)Quantity being made available in India is NOT enough to meet Indian needs and affordable (Yes-1; No-0)There are Indian manufacturers capable of (already making or prepared to) making this drug (Yes- 1; No-0)Will Govt action be needed to provide FTO to Indian manufacturers (if drug proven important)?SCORE: DRUG POTENTIAL (taken from Heat map - Drug Potential)With current info available on drug, is it worthwhile for the GoI to take action to provide FTO for Indian manufacturers?Drug candidate
34
Chloroquine0%NANANA0%#REF!None reqdChloroquine
35
Hydroxychloroquine0%NANANA0%None reqdHydroxychloroquine
36
Remdesivir100%111100%Await CT dataRemdesivir
37
Lopinavir/Ritonavir0%NANANA0%None reqdLopinavir/Ritonavir
38
Favipiravir50%111100%0Favipiravir
39
Baloxavir Marboxil100%111100%Await CT dataBaloxavir Marboxil
40
Darunavir0%NANANA0%None reqdDarunavir
41
Ribavirin + IFN beta0%NANANA0%None reqdRibavirin + IFN beta
42
Galidesivir0%NANANA0%None reqdGalidesivir
43
Oseltamivir0%NANANA0%None reqdOseltamivir
44
Umifenovir0%NANANA0%None reqdUmifenovir
45
Camostat mesylate0%NANANA0%None reqdCamostat mesylate
46
Ruxolitinib100%01167%Await CT dataRuxolitinib
47
Interferon beta0%NANANA0%None reqdInterferon beta
48
Tocilizumab0%NANANA0%None reqdTocilizumab
49
Ustekinumab100%111100%Await CT dataUstekinumab
50
Nigericin0%NANANA0%None reqdNigericin
51
Teicoplanin0%NANANA0%None reqdTeicoplanin
52
Ivermectin0%NANANA0%None reqdIvermectin
53
Source: TFORD-COVID19-India (c) Venture Center, 2020
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100