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Metadata elementDescriptionExampleValue Value 2Value 3Extend as needed
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RRID TermTools or resources used as part of the model, simulation, or data processing (henceforth referred to as project) OpenCORSimulinkMATLAB o²S²PARC
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RRID IdentifierResources identifier (with 'RRID:') associated with the project submission and its tools and resourcesRRID:SCR_019001RRID:SCR_014744 RRID:SCR_001622RRID:SCR_018997
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Ontology TermOntology term (human-readable) associated with the project submissionHeartbaroreceptor feedback control of blood pressureintrinsic cardiac nervous systemvagus nerve stimulation
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Ontology IdentifierAssociated ontology identifier from SciCrunchUBERON:0000945GO:0001978N/AILX:0428559
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Ten Simple Rules (TSR) See TSR conformance for a definition of the LevelsExample
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TSR Column TypeColumn type. Valid values are: Link, Text, Rating, Target, Target JustificationLinkLinkLinkRatingTargetTarget JustificationText
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TSR1: Clearly Defined ContextDescription of use cases for the project.https://doi.org/10.1088/1741-2552/ad1610https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdfComprehensive
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TSR2: Use of Appropriate DataLinks to data that was used to create, validate, test, etc. the project.https://doi.org/10.1088/1741-2552/ad1610https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdfExtensive
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TSR3a: VerificationLink to test suite for project.
https://github.com/ITISFoundation/openCOR-viewer/blob/main/.github/workflows/check-image.yml
https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdf
https://github.com/ITISFoundation/CardiovascularControl-DBI/blob/main/.github/workflows/build-test-publish.yml
Extensive
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TSR3b: Verification ResultsLink to test results from running the tests for the project, e.g., on the o²S²PARC platform
https://github.com/ITISFoundation/openCOR-viewer/actions
https://github.com/ITISFoundation/CardiovascularControl-DBI/actions
https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdf
https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdf
All TSR3 items are covered by the rating on the TSR3a row
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TSR3c: Evaluation Within ContextLink to scientific validation (experimental comparator), sensitivity analysis and uncertainty quantification for the project in the context of the use cases described in TSR1.https://doi.org/10.1088/1741-2552/ad1610https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdf
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TSR4: Explicitly Listed LimitationsLink to documentation of known issues and limitations of the project.https://doi.org/10.1088/1741-2552/ad1610https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdfComprehensive
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TSR5: Version Control Link to primary forge repository for the project. For example, o²S²PARC, github, or gitlab instance.
https://models.physiomeproject.org/workspace/b01
https://github.com/Daniel-Baugh-Institute/CardiovascularControl/tree/main/v03
https://osparc.io/study/65a52908-1b13-11ee-9cd1-02420a0b1bed
https://osparc.io/study/65a52908-1b13-11ee-9cd1-02420a0b1bed
Extensive
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TSR6: Adequate DocumentationLink to user and/or developer documentation for the project.
https://doi.org/10.6084/m9.figshare.23624622
https://github.com/Daniel-Baugh-Institute/CardiovascularControl/tree/main/v03#readme
https://doi.org/10.26275/wabs-qul8
https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdf
Comprehensive
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TSR7a: Broad Dissemination: ReleasesLink to the download or release page for the project, e.g., on the SPARC Portal.
https://models.physiomeproject.org/workspace/b01/@@shortlog
https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdfExtensive
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TSR7b: Broad Dissemination: IssuesLink to project issue tracker.https://models.physiomeproject.org/e/611https://github.com/Daniel-Baugh-Institute/CardiovascularControl/issues
All TSR7 items are covered by the rating on the TSR7a row
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TSR7c: Broad Dissemination: LicenseLink to project license.https://www.gnu.org/licenses/gpl-3.0.html
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TSR7d: Broad Dissemination: PackagesLink to language ecosystem package repository. For example, PyPI for python projects.
https://models.physiomeproject.org/workspace/b01
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TSR7e: Broad Dissemination: InteractiveLink to the project on an interactive software hosting platform e.g. o²S²PARC
https://osparc.io/study/1170826c-9a64-11ee-8b3c-02420a0b1983
https://osparc.io/study/65a52908-1b13-11ee-9cd1-02420a0b1bed
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TSR8a: Independent Reviews Links to reviews of project by independent members of the community.https://doi.org/10.1088/1741-2552/ad1610https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdfExtensive
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TSR8b: External CertificationLink to external certification of project.
All TSR8 items are covered by the rating on the TSR8a row
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TSR9: Competing Implementation Testing Link to benchmarking against other projects operating in the same domain.https://doi.org/10.1088/1741-2552/ad1610https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdfAdequate
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TSR10a: Relevant standardsList and/or link to standards/guidelines that this project conforms to or implements.
https://www.imagwiki.nibib.nih.gov/content/10-simple-rules-conformance-rubric
https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdf
https://doi.org/10.1186/s12967-020-02540-4
Adequate
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TSR10b: Standards AdherenceLink to demonstration that project conforms to standard.https://aiche.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Faic.18033&file=aic18033-sup-0001-Supinfo.pdf
All TSR10 items are covered by the rating on the TSR10a row
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Input/Output InformationDescriptionExampleValue Value 2Value 3Extend as needed
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Number of InputsIn o²S²PARC, "number of inputs" is equivalent to the number of parameterized input ports (i.e., service ports in the pipeline with attached 'Parameter' nodes). For custom code, number of inputs is the number of input parameters for the code. E.g. [out1, out2]=mymodel(param1, param2, param3) has 3 inputs even if a single parameter is a matrix of multiple values.12
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Input Parameter nameName of the parameterInhibitory stimulationVNS aff. frequencyVNS eff. frequency
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Input Parameter typeType (bool, int/enum, real, complex/phasor, vector, array, table, field, structure, file, other)Realrealreal
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Input Parameter description
Description of what the parameter represents
Frequency of electrical field stimulation between 0 and 10 Hz for inhibitory nitrergic and purinergic stimulation,
Vagus Nerve Stimulation Afferent Frequency
Vagus Nerve Stimulation Efferent Frequency
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Input Units string or 'N/A'HzHertzHertz
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Input Default valueDefault value for the parameter40.51
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Input ConstraintsRange [min, max] of acceptable parameter values, or other constraints as formulas / sets[0, 10]
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Number of OutputsIn o²S²PARC, "number of outputs" is equivalent to number of output ports with attached 'Probes'. For custom code, number of inputs is the number of input parameters for the code. E.g. [out1, out2]=mymodel(param1, param2, param3) has 2 outputs even if a single output is a matrix of multiple values.13
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Output Parameter nameName of the parameterTensionArterial PressureElastanceRR intervals
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Output Parameter typeType (bool, int/enum, real, complex/phasor, vector, time series, array, table, field, structure, file, other)Time seriestime seriestime seriestime series
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Output Parameter description
Description of what the parameter represents
Active gastric tension
2-columns array representing the evolution of arterial pressure in time
2-columns array representing the time evolution of left ventricular elastance
2-columns array representing the time evolution of RR intervals (inverse of the heart rate)
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Output Units string or 'N/A'kPAmm Hgmm Hg / mLseconds
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Output ConstraintsRange [min, max] of possible output values, or other constraints as formulas / sets
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