MUTYH Calculations
 Share
The version of the browser you are using is no longer supported. Please upgrade to a supported browser.Dismiss

View only
 
 
ABCDEFGHIJKLMNOPQRSTUVWXYZAA
1
Results Using 23andMe Frequencies
2
3
Total Population Considered*4,000,000
4
*10 million 23andMe customers, ~50% have done health screen; 80% customers Northern European)
5
Allele
Observed in 23andMe NE PopN*
Allele Frequency
**per date reported in 23andMe 510(K) application
6
Wild Type (p)00.98025000000.99012500
7
G396D (q)00.01160000000.00580000Frequency0.990125000.005800000.002100000.001975001.00000000
8
Y179C (r)00.00420000000.00210000VariantWT (p)G396D (q)Y179C (r)Other (s)Total
9
Other (s)00.00395000000.001975000.99012500WT (p)0.980347520.005742730.002079260.001955500.99012500
10
Total01.00000000001.000000000.00580000G396D (q)0.005742730.000033640.000012180.000011460.00580000
11
0.00210000Y179C (r)0.002079260.000012180.000004410.000004150.00210000
12
p^200.98034751560.00197500Other (s)0.001955500.000011460.000004150.000003900.00197500
13
q^200.0000336400
14
r^200.0000044100
Freq observed
% of total mut observed
15
s^200.0000039006
Total observed G396D (q)
00.01160000.587342
16
2pq00.0114854500
Total observed Y179C (r)
00.00420000.212658
17
2pr00.0041585250
Total expected "other"
00.00395000.200000
18
2ps00.0039109938Total00.019750
19
2qr00.0000243600
20
2qs00.0000229100
21
2rs00.0000082950
22
Total01.0000000000
23
24
Frequency
Total People Sample
25
Total MAP Cases0.00009752390.06
26
Total MAP Detected with Y/G analysis
0.00006241249.64
27
Total MAP missed with Y/G0.00003511140.42
28
Total MAP Detected stepwise0.00009362374.46
29
Total missed by stepwise0.0000039015.60
30
Missed by stepwise0.04000000160,000.00
31
For Stepwise - Total to Sequence0.0157375962,950.36
32
Total with normal 23andMe result0.984262413,937,049.64
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
Loading...