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1 | ID | Status | Title | Authors | ||||||||||||||||||||||
2 | 3 | Oral | scBasset: Sequence-based modeling of single cell ATAC-seq using convolutional neural networks | Han Yuan (Calico Life Sciences)*; David R Kelley (Calico Life Sciences) | ||||||||||||||||||||||
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5 | 6 | Oral | Sparse dictionary learning recovers pleiotropy from human cell fitness screens | Joshua Pan (Broad Institute)* | ||||||||||||||||||||||
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8 | 8 | Oral | MAVE-NN: learning genotype-phenotype maps from multiplex assays of variant effect | Justin B Kinney (Cold Spring Harbor Laboratory)* | ||||||||||||||||||||||
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11 | 17 | Oral | Towards More Realistic Simulated Datasets for Benchmarking Deep Learning Models in Regulatory Genomics | Eva I Prakash (Stanford University); Avanti Shrikumar (Stanford University)*; Anshul Kundaje (Stanford University) | ||||||||||||||||||||||
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14 | 22 | Oral | Looking at the BiG picture: Incorporating bipartite graphs in drug response prediction | David Earl Hostallero (McGill University)*; Jessica Li (McGil University); Amin Emad (McGill University) | ||||||||||||||||||||||
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17 | 25 | Oral | A Graph Neural Network Approach to Molecule Carcinogenicity Prediction | Philip Fradkin (Vector Institute)*; Adamo Young (University of Toronto); Lazar Atanackovic (University of Toronto); Leo J Lee (University of Toronto); Brendan Frey (U. Toronto); Bo Wang (Vector Institute) | ||||||||||||||||||||||
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20 | 33 | Oral | sc-DoRI: Gene Regulatory inference from single cell multi-omics data using Interpretable Deep Learning | Manu Saraswat (German Cancer Research Center(DKFZ) and European Molecular Biology Laboratory(EMBL))*; Moritz Mall (German Cancer Research Center (DKFZ)); Oliver Stegle (German Cancer Research Center (DKFZ) & EMBL Heidelberg) | ||||||||||||||||||||||
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23 | 39 | Oral | Inferring peptide coefficients from quantitative mass spectrometry data with deep learning | Ayse Dincer (Univeristy of Washington); Yang Young Lu (University of Washington); Sewoong Oh (University of Washington); William S Noble (University of Washington)* | ||||||||||||||||||||||
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26 | 40 | Oral | A segmentation error aware probabilistic clustering model for highly multiplexed imaging data | Yuju Lee (University of Toronto)*; Alina Selega (Lunenfeld-Tanenbaum Research Institute); Kieran Campbell (University of Toronto) | ||||||||||||||||||||||
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29 | 41 | Oral | The rate-distortion explanation identifies causal mutations driving drug resistance in bacterial whole-genome sequence data | Nick Dexter (Simon Fraser University)*; Morteza M. Saber (McGill University); B. Jesse Shapiro (McGill University); Leonid Chindelevitch (Imperial College London); Maxwell Libbrecht (Simon Fraser University) | ||||||||||||||||||||||
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32 | 43 | Oral | scOrigami: Prediction of 3D chromatin structure and cis-regulatory interaction networks from single-cell chromatin accessibility data | Vianne R Gao (Weill Medical College)* | ||||||||||||||||||||||
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35 | 44 | Oral | Unsupervised integration of single-cell multi-omics datasets with disproportionate cell type representation | Pinar Demetci (Brown University); Rebecca Santorella (Brown University); Bjorn Sandstede (Brown University); Ritambhara Singh (Brown University)* | ||||||||||||||||||||||
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38 | 51 | Oral | Deep generative models of protein structure create new and diverse proteins | Zeming Lin (Facebook AI Reseach)*; Tom Sercu (FAIR); yann lecun (Facebook); Alex Rives (FAIR) | ||||||||||||||||||||||
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41 | 56 | Oral | Towards data-driven design of context-specific regulatory elements | Peter Bromley (Altius Institute for Biomedical Sciences); Wouter Meuleman (Altius Institute for Biomedical Sciences)* | ||||||||||||||||||||||
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44 | 58 | Oral | Semi-supervised single-cell cross-modality translation using Polarbear | Ran Zhang (University of Washington); William S Noble (University of Washington)*; Jean-Philippe Vert (Google) | ||||||||||||||||||||||
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47 | 64 | Oral | Statistical correction of input gradients for black box models trained with categorical input features | Antonio Majdandzic (CSHL); Peter K. Koo ()* | ||||||||||||||||||||||
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50 | 4 | Spotlight | Towards a Better Understanding of Reverse-Complement Equivariance for Deep Learning Models in Genomics | Hannah Zhou (Harvard University); Avanti Shrikumar (Stanford University)*; Anshul Kundaje () | ||||||||||||||||||||||
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53 | 5 | Spotlight | Multimodal Pre-Training Model for Sequence-based Prediction of Protein-Protein Interaction | Yang Xue (Baidu Inc.)*; Zijing Liu (Baidu Inc.); Xiaomin Fang (Baidu Inc.); Fan Wang (Baidu, Inc.) | ||||||||||||||||||||||
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56 | 9 | Spotlight | MuDCoD: Multi-Subject Community Detection in Dynamic Gene Networks | Ali Osman Berk Şapcı (Sabancı University); Shan Lu (University of Wisconsin-Madison); Oznur Tastan (Sabanci University)*; Sunduz Keles (University of Wisconsin-Madison) | ||||||||||||||||||||||
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59 | 10 | Spotlight | Simultaneous CUT&Tag profiling of the accessible and silenced regulome in single cells | Derek Janssens (Fred Hutchinson Cancer Research Center); Dominik J. Otto (Fred Hutchinson Cancer Research Center)*; Michael Meers (Fred Hutchinson Cancer Research Center); Kami Ahmad (Fred Hutchinson Cancer Research Center); Steve Henikoff (Fred Hutchinson Cancer Research Center); Manu Setty () | ||||||||||||||||||||||
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62 | 7 | Spotlight | Real-time pathogenicity prediction during genome sequencing of novel viruses and bacteria | Jakub M Bartoszewicz (Hasso Plattner Institute)*; Ulrich Genske (Hasso Plattner Institute); Bernhard Renard (Hasso Plattner Institute) | ||||||||||||||||||||||
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65 | 13 | Spotlight | Compound Screening with Deep Learning for Neglected Diseases: Leishmaniasis | Jonathan A J Smith (Layer 6 AI)*; Hao Xu (Queen's University); Xinran Li (Queens University); Laurence Yang (Queens University); Jahir Gutierrez (Layer 6 AI) | ||||||||||||||||||||||
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68 | 14 | Spotlight | Modeling and interpretation of label free live cell imaging accelerate morphology based in vitro chemical screens | Herve D Marie Nelly (insitro)* | ||||||||||||||||||||||
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71 | 16 | Spotlight | Accelerating in-silico saturation mutagenesis using compressed sensing | Jacob Schreiber (Stanford University)*; Surag Nair (Stanford University); Akshay Balsubramani (Stanford); Anshul Kundaje (Stanford University) | ||||||||||||||||||||||
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74 | 18 | Spotlight | Hi-C-LSTM: Learning representations of chromatin contacts using a recurrent neural network identifies genomic drivers of 3D genome conformation | Kevin B Dsouza (University of British Columbia)*; Max Libbrecht (Simon Fraser) | ||||||||||||||||||||||
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77 | 19 | Spotlight | A novel matrix factorization model for interpreting single-cell gene expression from biologically heterogeneous data | Kun Qian (China University of Geosciences); Shiwei Fu (Rutgers, The State University of New Jersey); Hongwei Li (China University of Geosciences); Wei Vivian Li (Rutgers, The State University of New Jersey)* | ||||||||||||||||||||||
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80 | 30 | Spotlight | scGraphReg: modeling gene regulations in single cells using multiomics and chromatin interactions | Alireza Karbalayghareh (Memorial Sloan Kettering Cancer Center)*; Divya Koyyalagunta (Weill Cornell Medicine ); Christina Leslie (Memorial Sloan Kettering Cancer Center) | ||||||||||||||||||||||
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83 | 32 | Spotlight | Tandem Mass Spectra Prediction for Small Molecules | Adamo Young (University of Toronto)*; Hannes Rost (University of Toronto); Bo Wang (Vector Institute) | ||||||||||||||||||||||
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86 | 26 | Spotlight | Contrastive Multiview Coding for Enzyme-Substrate Interaction Prediction | Apurva Kalia (Tufts University)*; Soha Hassoun (Tufts University); Dilip Krishnan (Google) | ||||||||||||||||||||||
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89 | 37 | Spotlight | Linking cells across single-cell modalities by synergistic matching of neighborhood structure | Borislav Hristov (University of Washington)*; William S Noble (University of Washington); Jeff Bilmes (UW) | ||||||||||||||||||||||
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92 | 34 | Spotlight | Clipper: p-value-free FDR control on high-throughput data from two conditions | Xinzhou Ge (UCLA)*; Yiling Chen (UCI); Jingyi Li (UCLA) | ||||||||||||||||||||||
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95 | 46 | Spotlight | Enzyme Activity Prediction of Sequence Variants on Novel Substrates using Improved Substrate Encodings and Convolutional Pooling | Zhiqing Xu (University of Toronto, Department of Chemical Engineering and Applied Chemistry)*; Jinghao Wu ( University of Toronto, Department of Chemical Engineering and Applied Chemistry); Yun S Song (UC Berkeley); Radhakrishnan Mahadevan (University of Toronto) | ||||||||||||||||||||||
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98 | 47 | Spotlight | Integrating unmatched scRNA-seq and scATAC-seq data and learning cross-modality relationship simultaneously | Ziqi Zhang (Georgia Institute of Technology)*; Xiuwei Zhang (Georgia Institute of Technology) | ||||||||||||||||||||||
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