BioSci – Top_Pharma
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Deal Size ($M)% of SizeUpfront Cash ($M)% of UpfrontTotal Dev/RegIND FilingPh I StartPh II StartPh III StartPh III % of TotalFDA FilingFDA ApprovalFDA % of TotalEU FilingMajor EUJapan FilingJapan+
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All Top AverageN=403$197.2126.9%$20.14263.1%$52.98$2.14$2.87$6.50$9.2217.4%$12.20$19.4336.7%$8.27$15.11$4.71$8.90
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Median$74.7037.5%$7.50373.3%$28.00$1.00$2.00$3.00$5.0017.9%$6.00$10.0035.7%$5.00$10.00$4.00$5.00
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Top Ph III AverageN=59$349.7520.2%$44.47159.0%$70.70$26.32$38.9255.0%$12.93$20.44$5.90$9.67
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Median$217.0020.7%$30.00150.0%$45.00$10.00$20.0044.4%$7.90$11.70$5.00$5.00
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Top Ph III AverageN=12$588.6415.5%$77.86117.1%$91.18$37.93$33.3336.6%$21.97$39.95$10.67$16.64
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2008+ Median$732.5011.5%$46.80180.0%$84.25$12.05$20.0023.7%$12.50$32.30$10.00$13.20
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Top Ph III AverageN=19$293.7622.5%$37.43176.2%$65.97$23.33$33.5750.9%$12.11$19.12$5.83$10.00
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2004-07 Median$225.0022.2%$30.00166.7%$50.00$12.50$25.0050.0%$10.00$16.00$5.00$7.50
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Top Ph III AverageN=16$430.2822.2%$48.12198.5%$95.53$38.11$66.1269.2%$6.83$14.83$3.75$5.83
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2001-03 Median$192.8019.5%$42.0089.3%$37.50$10.00$20.0053.3%$5.50$10.50$3.75$5.00
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Top Ph III AverageN=12$92.1326.7%$21.16116.2%$24.59$8.81$14.1757.6%$5.38$7.21$1.00$2.75
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1998-00 Median$77.5023.5%$5.00365.0%$18.25$6.13$15.0082.2%$5.00$10.00$1.00$2.75
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Top II AverageN=66$348.7123.2%$36.03224.6%$80.91$18.7323.1%$15.58$30.2537.4%$10.45$22.41$4.25$14.03
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Median$200.5023.2%$18.10256.9%$46.50$11.8025.4%$14.00$20.0043.0%$9.00$11.00$4.50$7.75
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Top II AverageN=16$647.5222.5%$56.36258.5%$145.71$32.2722.1%$23.55$66.9245.9%$12.13$31.92$4.71$24.49
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2008+ Median$454.5027.0%$37.50326.7%$122.50$15.0012.2%$20.00$42.0034.3%$10.00$23.50$5.00$15.00
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Top II AverageN=30$340.0924.0%$34.32237.7%$81.59$19.5123.9%$17.84$24.5730.1%$11.38$24.83$3.75$9.42
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2004-07 Median$226.0023.4%$18.10292.0%$52.85$15.0028.4%$15.00$20.0037.8%$8.75$14.15$3.00$7.50
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Top II AverageN=10$156.7121.7%$14.22238.9%$33.97$8.5025.0%$7.96$15.3445.2%$3.17$6.15$5.00$5.00
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2001-03 Median$105.6928.8%$10.00304.9%$30.49$10.0032.8%$6.93$15.0049.2%$2.50$3.96$5.00$5.00
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Top II AverageN=10$88.4925.0%$30.7971.8%$22.10$6.6330.0%$6.06$7.9435.9%$4.00$5.00#DIV/0!$4.80
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1998-00 Median$91.5020.5%$4.00468.8%$18.75$6.5034.7%$5.00$8.0042.7%$4.00$4.50#NUM!$4.00
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Top I AverageN=35$276.3231.3%$23.95361.2%$86.51$15.36$14.0216.2%$13.90$28.5133.0%$11.11$18.71$7.38$11.11
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Median$163.5027.5%$13.35337.1%$45.00$7.00$10.0022.2%$10.00$20.0044.4%$10.00$15.00$6.50$8.75
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Top I AverageN=7$605.2726.4%$54.39294.2%$160.00$41.20$19.7112.3%$21.50$43.9227.5%$17.00$27.17$10.75$18.50
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2008+ Median$530.0024.2%$30.00428.3%$128.50$15.00$15.0011.7%$17.50$40.0031.1%$20.00$27.50$11.50$12.00
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Top I AverageN=14$249.2434.6%$18.57464.8%$86.32$7.75$16.0518.6%$15.85$31.5536.6%$10.50$22.50$10.00$9.00
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2004-07 Median$206.2531.0%$14.00457.1%$64.00$6.25$10.0015.6%$10.00$20.0031.3%$10.00$20.00$10.00$10.00
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Top I AverageN=5$161.5335.8%$12.31469.5%$57.80$7.80$10.2017.6%$6.25$20.6035.6%#DIV/0!$14.00#DIV/0!$12.50
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2001-03 Median$163.5015.3%$12.90193.8%$25.00$5.00$5.0020.0%$5.50$10.0040.0%#NUM!$10.00#NUM!$12.50
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Top I AverageN=9$126.3736.1%$14.00325.8%$45.61$6.20$8.3818.4%$7.40$16.5636.3%$4.50$9.88$2.00$6.25
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1998-00 Median$90.0044.4%$10.00400.0%$40.00$5.00$6.0015.0%$5.00$10.0025.0%$5.00$6.25$2.00$4.25
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Top Pre AverageN=80$142.3036.5%$9.81530.0%$51.99$2.91$4.35$7.66$9.5418.3%$9.20$14.9028.7%$6.66$12.36$5.09$7.85
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Median$61.9346.8%$5.00580.0%$29.00$1.00$3.00$5.00$6.0020.7%$7.00$10.0034.5%$5.00$10.00$5.00$6.35
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Top Pre AverageN=18$266.2833.1%$16.37538.2%$88.11$8.00$4.70$11.20$19.3622.0%$12.93$23.4426.6%$10.75$17.31$6.40$8.95
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2008+ Median$207.0036.4%$10.00752.5%$75.25$3.75$4.50$10.00$15.0019.9%$12.00$22.5029.9%$10.00$15.00$5.00$10.00
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Top Pre AverageN=29$176.5835.2%$13.04476.2%$62.09$3.38$6.02$9.49$10.4416.8%$11.21$17.1427.6%$7.00$13.39$5.20$7.65
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2004-07 Median$104.0041.3%$8.00537.5%$43.00$3.50$4.00$6.50$7.5017.4%$7.30$14.7034.2%$5.50$12.35$5.00$5.00
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Top Pre AverageN=17$64.3853.8%$4.52766.2%$34.63$0.41$2.75$2.96$5.1014.7%$6.15$12.2535.4%$4.00$7.36$4.00$8.00
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2001-03 Median$55.0054.5%$3.30909.1%$30.00$0.35$2.00$2.75$5.0016.7%$7.00$10.0033.3%$4.50$5.00$2.00$5.00
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Top Pre AverageN=17$23.3351.7%$2.00602.5%$12.05$0.81$1.13$1.98$2.2919.0%$3.09$3.8231.7%$1.65$4.72$1.00$4.67
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1998-00 Median$20.5051.2%$1.001050.0%$10.50$1.00$1.00$2.00$2.0019.0%$3.50$3.0028.6%$0.75$5.00$1.00$4.00
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Top Lead AverageN=35$94.9335.6%$6.34532.3%$33.75$2.91$2.11$3.47$5.1415.2%$7.35$11.3533.6%$4.83$9.07$3.10$5.73
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Median$34.2544.5%$3.25469.2%$15.25$1.50$1.00$2.00$3.0019.7%$5.00$8.0052.5%$2.50$5.00$2.50$5.00
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Top Lead AverageN=2$234.6340.2%$17.75531.7%$94.38$10.00#DIV/0!$15.00$20.0021.2%$30.00$55.0058.3%$15.00$30.00#DIV/0!$10.00
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2008+ Median$234.6340.2%$17.75531.7%$94.38$10.00#NUM!$15.00$20.0021.2%$30.00$55.0058.3%$15.00$30.00#NUM!$10.00
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Top Lead AverageN=10$151.3735.0%$7.33723.6%$53.04$2.33$2.91$4.91$7.4014.0%$9.61$15.1028.5%$3.93$8.64$3.75$6.30
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2004-07 Median$133.7836.4%$4.501083.3%$48.75$0.50$3.00$4.00$7.0014.4%$5.00$10.0020.5%$2.50$5.00$3.75$5.00
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Top Lead AverageN=11$85.7232.3%$6.21445.4%$27.66$2.35$1.45$1.73$3.7013.4%$4.59$9.0032.5%$4.92$7.34$2.67$4.20
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2001-03 Median$24.5053.1%$5.00260.0%$13.00$2.00$1.00$1.50$3.0023.1%$3.25$10.0076.9%$3.25$4.50$2.50$2.00
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Top Lead AverageN=12$33.0639.8%$2.84463.4%$13.16$1.67$1.31$1.35$2.4318.5%$3.18$5.9144.9%$0.40$7.00#DIV/0!$6.00
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1998-00 Median$27.2536.7%$2.00500.0%$10.00$1.00$1.00$1.25$2.5025.0%$3.00$8.0080.0%$0.40$7.00#NUM!$6.00
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Top Disc AverageN=128$89.4330.3%$8.39323.1%$27.11$1.72$2.28$3.67$4.3416.0%$6.24$9.2734.2%$4.03$7.16$2.55$4.43
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Median$29.7547.1%$2.63532.3%$14.00$1.00$1.50$2.00$2.2015.7%$3.00$5.0035.7%$2.50$5.00$2.50$3.00
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Top Disc AverageN=9$347.6918.1%$33.79186.0%$62.86$15.00$6.57$10.67$17.2027.4%$15.70$22.6936.1%#DIV/0!$14.17#DIV/0!$10.00
85
2008+ Median$316.0024.5%$15.00516.7%$77.50$15.00$6.50$11.00$15.0019.4%$13.00$22.5029.0%#NUM!$15.00#NUM!$10.00
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Top Disc AverageN=35$127.1833.5%$8.00533.1%$42.65$2.09$2.62$3.90$6.4915.2%$9.40$13.1530.8%$6.39$10.84$3.25$5.77
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2004-07 Median$54.2553.5%$3.75773.3%$29.00$1.00$2.00$2.25$5.0017.2%$8.00$10.0034.5%$5.00$10.00$3.50$5.00
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90
Top Disc AverageN=35$67.3637.3%$6.65378.0%$25.14$1.37$1.19$3.01$3.2713.0%$5.43$9.8539.2%$2.33$3.79$0.75$2.69
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2001-03 Median$29.0052.9%$2.15714.0%$15.35$1.00$1.00$2.00$2.0013.0%$3.00$6.0039.1%$1.50$3.50$0.75$2.50
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Top Disc AverageN=49$30.7835.3%$3.38321.3%$10.86$1.12$1.10$1.50$2.0118.5%$2.76$3.6133.2%$2.85$3.20$2.33$2.25
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1998-00 Median$24.1034.2%$2.00412.5%$8.25$1.00$1.00$1.00$2.0024.2%$2.13$3.0036.4%$2.50$3.00$2.50$2.25
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