ABCDEFGHIJKLMNOPQRSTUVWXYZAAABACADAEAFAGAHAIAJAKALAMANAOAPAQ
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IDENTIFICATIONSAFETYDATAINFORMATION
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Substrate from ICOMSolvent Name CAS NumberFormulaOccupational Exposure none availableHazardsCHEM 21 RatingBoiling PointRelative Evaporation Rates Hansen Solubility ParameterUsesNotesGreener AlternativesPracticality of AlternativeReferences
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Bone
Glass
Ceramic
Leather
Metals, Paint, Paper, Plastics,Textile, Wood
(includes actual chemical name, other names from company)Using the American Conference of Governmental industrial Hygenists gives us (usually) the most conservative value of TLV.
ACGIH TLV- TWA (ppm)
NIOSH
OSHA
ECHA
WEEL
TWA mg/m3TLV-STEL (ppm)STEL (mg/m3)Carcinogenity based on ACGIH
A4: not classifiable as a human carcinogen
A3: Confirmed animal carcinogen with unknown relavance to humans
A2: Suspected human carcinogen
A1: confirmed carcinogen
Gray box colored in: Not listed
Here is where any hazard GHS pictograms are listedSafety ScoreHealth ScoreEnvironmental ScoreCHEM 21 Rating
HIGHLY HAZARDOUS = HH
HAZARDOUS =H
PROBLEMATIC =P
RECOMMENDED =R
compared to Butyl Acetate = 1δdδp δhWhat conservators use the solvent forEvery database should have a notes section for additional data(includes known and perhaps potential substitutes?) (hyperlinked to place in database?)Why haven't we already switched
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PaintAcetone67-64-1C3H6O2505945001210A4Flammable, Irritant535R55.751.9015.510.47.0Dissolving fats, oils, waxeshttps://pubchem.ncbi.nlm.nih.gov/compound/180
https://cool.culturalheritage.org/waac/wn/wn11/wn11-2/wn11-202.html
https://www.hansen-solubility.com/HSP-science/sphereVR.php
https://www.dispersetech.com/blog/post/properties-of-common-solvents.html
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Acetic Anhydride (Ac2O)108-24-7C4H6O314.2313A4Flammable, Corrosive, Irritant373P139.000.4616.011.710.2https://pubchem.ncbi.nlm.nih.gov/compound/Acetic-anhydride
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Heptanes142-82-5C7H1640016405002050x Flammable, Irritant, Health Hazard, Environmental Hazard627P98.502.8015.30.00.0https://www.fishersci.com/store/msds?partNumber=AC610361000&productDescription=N-HEPTANE+ANHYD&vendorId=VN00033901&countryCode=US&language=en
https://www.stevenabbott.co.uk/practical-solubility/hsp-basics.php
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Tert-Butyl Methyl Ether (MTBE, Methyl Tert-Butyl Ether)1634-04-4C5H12O50183367100A3Flammable, Irritant835H55.00no data available14.84.35.0https://pubchem.ncbi.nlm.nih.gov/compound/15413
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Hexanes110-54-3C6H1450176xxx Flammable, Irritant, Acute Toxiticity877H69.008.3014.90.00.0https://www.fishersci.com/store/msds?partNumber=H306SK4&productDescription=N-HEXANE+95%25+OPTIMA+4+L+SK&vendorId=VN00033897&countryCode=US&language=en
https://pubchem.ncbi.nlm.nih.gov/compound/Hexane
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Dichloromethane (DCM)75-09-2CH2Cl250174125435A3Health Hazard177H40.000.7117.07.37.1https://pubchem.ncbi.nlm.nih.gov/compound/Dichloromethane
https://www.sigmaaldrich.com/US/en/sds/sial/270997
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Benzene (Benzol, phenyl hydride)71-43-2C6H60.51.62.58A1Carcinogen, Health Hazard, Irritant, Flammable6103HH80.005.4018.40.02.0Organic SolventConfirmed Human Carcinogen A1See: Dimethyl Ether, Pentane, Cyclopentane, 1-4 Dioxane, Diethyl Ether, Toluenehttps://pubchem.ncbi.nlm.nih.gov/compound/benzene
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HMPA (Hexamethylphosphoramide) 680-31-9C6H18N3OPnot listednot listednot listednot listedA3Health Hazard197HH232.50no data available18.511.68.7https://pubchem.ncbi.nlm.nih.gov/compound/12679
https://www.echemi.com/sds/hexamethylphosphoramide-pid_Rock8640.html
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Carbon Tetrachloride56-23-5CCl45311063A2Acute Toxicity, Irritant, Health Hazard2710HH77.0012.8017.80.00.6HSP is for 0 dipole momenthttps://pubchem.ncbi.nlm.nih.gov/compound/5943
https://fscimage.fishersci.com/msds/90116.htm
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1,4-Dioxane (Dietheyelene diozide, diethylene ether)123-91-1C4H8O22072A3Flammable, Acute Toxicity, Carcinogen763H101.00no data available17.51.89.0Known animal carcinogen, no human data,
SVHC (substance of very high concern from the European Chemical Agency
https://www.sigmaaldrich.com/US/en/sds/sial/296309
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2-Methoxy-ethanol (Ethylene Glycol Monomethyl Ether)109-86-4C3H8O0.10.3not listednot listedFlammable, Irritant, Health Hazard393H46.000.5016.08.215.0
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2-Methoxyethanol (Methyl Cellosolve)109-86-4C7H80.10.3Flammable, Irritant, Health Hazard563P110.002.3018.01.42.0Dissolves wax, Thins Oilpetroleum basedTMO (2,2,25,5,-tetramethyloxolane) - replace other hydrocarbonshttps://siconserve.wpengine.com/wp-content/uploads/2021/12/Greener-Solvents-in-Conservation-ONLINE-VERSION-v5.pdf
https://www.hansen-solubility.com/HSP-science/sphereVR.php
https://www.fishersci.com/store/msds?partNumber=AC396891000&productDescription=2-METHOXYETHANOL&vendorId=VN00032119&countryCode=US&language=en
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1-Methyl-2-pyrrolidinone (NMP, N Mehtylpyrrolidinone, N-methyl-2-pyrrolidone)872-50-4C5H9NO156030120Irritant, Health Hazard197H202.00no data available18.012.37.2 https://pubchem.ncbi.nlm.nih.gov/compound/13387
https://www.fishersci.com/store/msds?partNumber=AC166370050&productDescription=NITROMETHANE-D3%2C+99+ATOM+5ML&vendorId=VN00032119&countryCode=US&language=en
https://www.sigmaaldrich.com/US/en/sds/sial/328634
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Acetic Acid (Glacial Acetic Acic, ethanoic acid)64-19-7C2H4O210251537Flammable, Corrosive373P118.000.9714.58.013.5https://pubchem.ncbi.nlm.nih.gov/compound/176
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Acetonitrile75-05-8C2H3N2033A4Flammable, Irritant433P82.005.7915.318.06.1https://www.hansen-solubility.com/HSP-science/sphereVR.php
https://pubchem.ncbi.nlm.nih.gov/compound/6342
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Ammonia (ammonium hydroxide)7664-41-7NH325173524A4Corrosive, Acute Toxicity, Environmental Hazard-33.05no data available13.716.718.8Removes copper corrosion, cleans metal threads on textileshttps://www.stevenabbott.co.uk/practical-solubility/hsp-basics.php
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1 Butanol (Butanol, n-butanol, Butan-1-ol)71-36-3C4H9OH2061Flammable, Irritant, Skin Irritant343R117.600.4616.05.715.8https://www.fishersci.com/store/msds?partNumber=A4004&productDescription=1-BUTANOL+SPECTRANALYZE+CR+4L&vendorId=VN00033897&countryCode=US&language=en
https://www.stevenabbott.co.uk/practical-solubility/hsp-basics.php
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Amyl Acetate (1-Pentyl Acetate)628-63-7C7H14O250266100532Flammable149.200.4215.83.36.1https://pubchem.ncbi.nlm.nih.gov/compound/12348
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Anisole (methoxybenzene)100-66-3C7H8OFlammable, Irritant415R154.00no data available17.84.46.9https://pubchem.ncbi.nlm.nih.gov/compound/7519
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Benzyl Alcohol (phenylmethanol, phenyl carbinol)100-51-6C7H8O15not listednot listedIrritant127P205.05no data available18.46.313.7solvent for dyes, gelatin, casein, cellulose acetate, waxes, and Shellachttps://www.talasonline.com/images/PDF/MSDS/benzyl_alcohol.pdf
https://pubchem.ncbi.nlm.nih.gov/compound/244
https://cameo.mfa.org/wiki/Benzyl_alcohol#:~:text=Benzyl%20alcohol%20is%20used%20as,soaps%20as%20a%20Wetting%20agent.
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Butyl Acetate (n-BuOAc)123-86-4C6H12O250238150712Flammable, irritant423R124-1261.0015.83.76.3https://www.sigmaaldrich.com/US/en/sds/sial/287725
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Carbon Disulfide75-15-0CS213.13A4Flammable, Irritant, Health Hazard977HH46.00no data available20.20.00.6HSP is for 0 dipole momenthttps://pubchem.ncbi.nlm.nih.gov/compound/751
https://www.sigmaaldrich.com/US/en/sds/sial/335266
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Chlorobenzene108-90-7C6H5Cl1046A3Flammable, irritant, environmental hazard327P132.001.0019.04.32.0 https://pubchem.ncbi.nlm.nih.gov/compound/7964
https://www.fishersci.com/store/msds?partNumber=B255500&productDescription=CHLOROBENZENE+MONO+CERT+500ML&vendorId=VN00033897&countryCode=US&language=en
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Chloroform67-66-3CHCl31049A3 Probable Carcinogen, Acute Toxicity, Health Hazard275HH61.00no data available17.83.15.7Lacquer solvent; solvent for PerspexNot used very much anymore??See: Dimethyl Ether stored under pressurehttps://pubchem.ncbi.nlm.nih.gov/compound/6212#section=Taste Materials For Conservation, C. V Horie
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CO2 Sc (Supercritical CO2)CO2-----Emissions?-no data availableRemove fungi and bacteria from artifacts, drycleaning, potentially remove pesticides from woodNeeds high pressure technology, which is expensive
Used industrially and in pharma
https://www.researchgate.net/publication/320184747_Supercritical_carbon_dioxide_the_art_of_technology_in_art_conservation
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Cyclohexane (Hexahydrobenzene)110-82-7C6H12 100335.38637P81.004.5016.80.00.2https://www.hansen-solubility.com/HSP-science/sphereVR.php
Materials For Conservation, C. V Horie
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Cyclohexanone108-94-1C6H10O208050200A3325P156.00no data available17.88.45.1
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PaintD Limonone (d-p-Mentha-1,8-diene 4-Isopropenyl-1-methylcyclohex
ene)
5989-27-5C10H1630not listednot listednot listedFlammable, Acute Toxicity, Irritant, Environmental Hazard176.000.1617.21.84.3Diluting paints, dissolving alkyd resins, dissolving natural resinshttp://www.weberart.com/assets/asaferartstudio.pdf
https://www.chemcentral.com/media/product_attribute/sds_file/s/d/sds_file-70040.pdf
https://pubchem.ncbi.nlm.nih.gov/compound/D-Limonene
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DCE (Ethylene dichloride)107-06-02C2H4Cl2104028A4Flammable, Irritant, Health Hazard4103HH84.006.5018.07.44.1https://pubchem.ncbi.nlm.nih.gov/compound/11
https://www.fishersci.com/store/msds?partNumber=E175500&productDescription=1%2C2-DICHLOROETHAN+CR+ACS+500ML&vendorId=VN00033897&countryCode=US&language=en
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Diacetone Alcohol (DAA)C6H12O2Irritant, Flamable168.000.2015.88.210.8https://pubchem.ncbi.nlm.nih.gov/compound/31256
https://www.stevenabbott.co.uk/practical-solubility/hsp-basics.php
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Diethyl Ether60-29-7C4H10O40012105001520Irritant, Flamable1037HH34.00no data available14.52.94.6https://pubchem.ncbi.nlm.nih.gov/compound/3283
https://www.sigmaaldrich.com/US/en/sds/sial/296082
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Diisopropyl Ether (Isoppropyl ether)108-20-3C6H14O25010403101300Flammable, Acute Toxicity 935H69.00no data available15.13.23.2https://www.fishersci.com/store/msds?partNumber=AC180680250&productDescription=ISOPROPYL+ETHER+STABILI+25LTI&vendorId=VN00032119&countryCode=US&language=en
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Dimethyl Ether115-10-6C2H6O 1000not listed not listednot listedFlammable, Acute Toxicity-24.00no data available15.26.15.7https://www.lindeus.com/-/media/corporate/praxairus/documents/sds/dimethyl-ether-c2h6o-safety-data-sheet-sds-p4589.pdf?la=en
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DMAc (N,N Dimethyl Acetamide)127-19-5C4H9NO1035not listednot listedA3Irritant, Health Hazard159H166.000.1716.811.59.4https://pubchem.ncbi.nlm.nih.gov/compound/31374
https://www.fishersci.com/store/msds?partNumber=D1601&productDescription=N%2CN-DIMETHYLACETAMIDE+GC+HS+1L&vendorId=VN00033897&countryCode=US&language=en
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DME (1,2 Dimethoxyethane, Ethylene Glycol Dimethyl Ether) 110-71-4C4H10O2not listed10not listednot listedFlammable, Irritant, Health Hazard7103H85.00no data available15.46.36.0https://pubchem.ncbi.nlm.nih.gov/compound/8071
https://fscimage.fishersci.com/msds/09450.htm
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DMPU (1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, N,N'-dimethylpropyleneurea) 7226-23-5C6H12N2Onot listednot listednot listednot listedCorrosive, Irritant, Health Hazard167H246.00no data available17.89.59.3https://pubchem.ncbi.nlm.nih.gov/compound/81646
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DMSO (Dimethyl sulfoxide)67-68-5C2H6OSnot listednot listednot listednot listedIrritant115P189.00no data available18.416.410.2https://pubchem.ncbi.nlm.nih.gov/compound/679
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Ethanol (Ethyl Alcohol)64-17-5C2H6O10001880xxA3 Flammable433R78.202.8015.88.819.4Solvent; dehydrating waterlogged material; cleaninghttps://pubchem.ncbi.nlm.nih.gov/compound/702
https://www.hansen-solubility.com/HSP-science/sphereVR.php
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Ethyl Acetate141-78-6C4H8O24001440xxxFlammable, Irritant 533R77.004.1015.85.37.2http://www.refinishersonline.com/store/pdfs/1452637142.pdf
https://www.hansen-solubility.com/HSP-science/sphereVR.php
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Ethylene Glycol107-21-1C2H6O2 25655010Irritant125R197.30<0.0117.011.026.0https://pubchem.ncbi.nlm.nih.gov/compound/174
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Formic Acid (Methanoic acid)68-18-6CH2O259.41019Corrosive 373P101.002.1014.610.014.0https://pubchem.ncbi.nlm.nih.gov/compound/284#section=Dissociation-Constants
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Isopropyl Acetate (iPrOAc)108-21-4C5H10O2100417150626Flammable, irritant423R89.003.0014.94.58.2https://www.sigmaaldrich.com/US/en/sds/sigald/537462
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Isopropyl Alcohol (Isopropanol, 2 propanol)67-63-0C3H8O200540400980A4Flammable433R82.302.1015.86.116.4Solvent; soften and swell leather; with parchmenthttps://www.dispersetech.com/blog/post/properties-of-common-solvents.html
https://www.stevenabbott.co.uk/practical-solubility/hsp-basics.php
https://pubchem.ncbi.nlm.nih.gov/compound/3776
https://www.sigmaaldrich.com/US/en/sds/sigma/i9516
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Me THF (2-Methyltetrahydrofuran)97-47-9C5H10O not listednot listednot listednot listedFlammable, Corrosive, Irritant653P80.00no data availableSigma Aldrich says Biorenewable, attached in references is the Greener Chemistry Paper. Sigma Aldrich suggests that this replaces DMSO, THF, and Methylene chloride. It is a Biomass derived solventhttps://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cssc.201100780
https://monumentchemical.com/uploads/files/SDS/2-MethylTHF_-_SDS.pdf
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Methanol (Methyl Alcohol)67-56-1CH4O200260250325A3Flammable, Acute Toxicity, Health Hazard475R65.005.2014.712.322.3https://pubchem.ncbi.nlm.nih.gov/compound/887,
https://www.sigmaaldrich.com/US/en/sds/sial/322415
https://beta-static.fishersci.com/content/dam/fishersci/en_US/documents/programs/education/regulatory-documents/sds/chemicals/chemicals-m/S25426A.pdf
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Methyl Acetate79-20-9C3H6O2200606250757Flammable, Irritant535P57.00no data available15.57.27.6https://pubchem.ncbi.nlm.nih.gov/compound/6584
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Methyl Ethyl Ketone (MEK, 2-Butanone) 78-93-3C4H8O200590300885Flammable, Irritant533R80.003.7016.09.05.1https://pubchem.ncbi.nlm.nih.gov/compound/6569
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Methyl isobutyl ketone (MIBK, 4-Methyl-2-pentanone)108-10-1C6H12O208275307A3Flammable, Irritant423R117.001.6015.36.14.1 https://pubchem.ncbi.nlm.nih.gov/compound/Methyl-isobutyl-ketone
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Methylcyclohexane (Me-Cyclohexane)108-87-2C7H144001610not listednot listedFlammable, Irritant, Health Hazard, Enviromental Hazard627P100.90no data available16.00.01.0https://pubchem.ncbi.nlm.nih.gov/compound/Methylcyclohexane
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PaintMineral Spirits------no data availableDiluting paints, dissolving alkyd resinshttp://www.weberart.com/assets/asaferartstudio.pdf
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NitroMethane (Nitrocarbol)75-52-5CH3NO22050not listednot listedA3Flammable, Irritant1023HH101.001.3015.818.86.1https://pubchem.ncbi.nlm.nih.gov/compound/6375
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Pentane109-66-0C5H12 100029507502250Flammable, Irritant, Health Hazard, Environmental Hazard837H36.0028.6014.50.00.0https://pubchem.ncbi.nlm.nih.gov/compound/8003
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Pyridine110-86-1C5H5N13.1Not listedNot ListedA3Flammable, Irritant423H115.00no data available19.08.859.0https://pubchem.ncbi.nlm.nih.gov/compound/1049
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Shellsol A 10064742-95-6----Flammable, Acute Toxicity, Irritant, Environmental Hazard150-1850.20Contains Cumene and Benzenehttps://ch-msds.shell.com/MSDS/000000000892_US_EN.pdf
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Shellsol A 15064742-94-5----Irritant, Acute Toxicity, Environmental Hazard179-2141.00Contains Cumene, Benzene, Napthalenehttps://ch-msds.shell.com/MSDS/000000000882_US_EN.pdf
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Sulfolane (Tetramethylene sulfone)126-33-0C4H8O2Snot listednot listednot listednot listedIrritant197H287.00no data available17.817.48.7 https://pubchem.ncbi.nlm.nih.gov/compound/31347
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Tert-butanol (Tert-butyl alcohol, 2 methyl-2-propanol)75-65-0C4H10O100303150450A4Flammable, Irritant433R82.001.0515.25.114.7https://pubchem.ncbi.nlm.nih.gov/compound/6386
https://www.sigmaaldrich.com/US/en/sds/sial/471712
https://fscimage.fishersci.com/msds/22630.htm
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Tetrahydrofuran (THF, Oxolane)109-99-9C4H8O 50147100295A3Flammable, Irritant, Health Hazard675P66.00816.85.78.0https://pubchem.ncbi.nlm.nih.gov/compound/8028
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Triethanolamine (TEA, Trolamine)102-71-6C6H15NO3not listed5not listednot listedCorrosive, Irritant, Health Hazard673H89.00no data available17.37.621.0https://pubchem.ncbi.nlm.nih.gov/compound/7618
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PaintTurpenoid8052-41-3100350not listednot listedflammable, Toxicity154-202ModerateDiluting Paint, Dissolving Alkyd Resinshttp://www.weberart.com/assets/asaferartstudio.pdf
https://www.sigmaaldrich.com/US/en/sds/mm/sx0995
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PaintTurpenoid Natural------Hazardous to the Aquatic EnvironmentDiluting paints, dissolving alkyd resinsComposition of Hazardous ingredients: D Limonene, Amino 2 Methyl Propanolhttp://www.weberart.com/assets/asaferartstudio.pdf
https://www2.pcad.edu/Facilities/health_safety/SDS/Painting/Solvents/Martin%20F.%20Weber/Turpenoid%20Natural.pdf
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PaintTurpentine (Triethyl citrate)79-93-0
8006-64-2?
C10H1620112None ListedNone ListedA4Flammable, Irritant, Health Hazard, Environmental Hazard157 - 176FastDiluting paints, dissolving alkyd resins, dissolving natural resinshttp://www.weberart.com/assets/asaferartstudio.pdf
https://dhss.delaware.gov/dph/files/turpentfaq.pdf
https://ace.infotrac.net/getmsds.aspx?sku=1433085
https://pubchem.ncbi.nlm.nih.gov/compound/6506
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Water7732-18-5H2ONoneNoneNone NoneNONE111R100.000.3615.516.042.3Universal Solventhttps://www.dispersetech.com/blog/post/properties-of-common-solvents.html
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Xylene (1,2 Dimethylbenzene)1330-20-7C8H1020130150665A4Flammable, Corrosive, Irritant, Health Hazard425P138.000.7517.81.03.1Dissolves water based finishes, thins varnishesNapthenic Solvents? Paraffinic Solvents?takes a longer time?https://www.cbgbiotech.com/blog/what-to-consider-when-selecting-substitutes-for-xylene
https://pubchem.ncbi.nlm.nih.gov/compound/Xylene
https://www.hansen-solubility.com/HSP-science/sphereVR.php
https://pubchem.ncbi.nlm.nih.gov/compound/792
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https://www.sigmaaldrich.com/US/en/sds/sigald/534056
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