palatine-tonsil-v1.1

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1	Anatomical Structures Cell Types and Biomarkers Table for Palatine Tonsil
2
3	Author Name(s):	Werner Müller; Silvia Rüberg; Andreas Bosio
4	Author ORCID(s):	0000-0002-1297-9725; 0009-0008-1003-987X; 0000-0001-9776-2535
5	Reviewer(s):	Andrea J. Radtke; Ellen M. Quardokus
6	Reviewer ORCID(s):	0000-0003-4379-8967;0000-0001-7655-4833
7	General Publication(s):
8	Data DOI:	https://doi.org/10.48539/HBM674.FKTS.997
9	Date:	June 15, 2024
10	Version Number:	V1.1
11	AS/1	AS/1/LABEL	AS/1/ID	AS/1/NOTE	AS/1/ABBR	AS/2	AS/2/LABEL	AS/2/ID	AS/2/NOTE	AS/2/ABBR	AS/3	AS/3/LABEL	AS/3/ID	AS/3/NOTE	AS/3/ABBR	AS/4	AS/4/LABEL	AS/4/ID	AS/4/NOTE	AS/4/ABBR	AS/5	AS/5/LABEL	AS/5/ID	AS/5/NOTE	AS/5/ABBR	AS/6	AS/6/LABEL	AS/6/ID	AS/6/NOTE	AS/6/ABBR	CT/1	CT/1/LABEL	CT/1/ID	CT/1/NOTE	CT/1/ABBR	CT/2	CT/2/LABEL	CT/2/ID	CT/2/NOTE	CT/2/ABBR	BGene/1	BGene/1/LABEL	BGene/1/ID	BGene/1/NOTE	BGene/1/ABBR	BGene/2	BGene/2/LABEL	BGene/2/ID	BGene/2/NOTE	BGene/2/ABBR	BGene/3	BGene/3/LABEL	BGene/3/ID	BGene/3/NOTE	BGene/3/ABBR	BGene/4	BGene/4/LABEL	BGene/4/ID	BGene/4/NOTE	BGene/4/ABBR	BGene/5	BGene/5/LABEL	BGene/5/ID	BGene/5/NOTE	BGene/5/ABBR	BGene/6	BGene/6/LABEL	BGene/6/ID	BGene/6/NOTE	BGene/6/ABBR	BGene/7	BGene/7/LABEL	BGene/7/ID	BGene/7/NOTE	BGene/7/ABBR	BGene/8	BGene/8/LABEL	BGene/8/ID	BGene/8/NOTE	BGene/8/ABBR	BGene/9	BGene/9/LABEL	BGene/9/ID	BGene/9/NOTE	BGene/9/ABBR	BGene/10	BGene/10/LABEL	BGene/10/ID	BGene/10/NOTE	BGene/10/ABBR	BProtein/1	BProtein/1/LABEL	BProtein/1/ID	BProtein/1/NOTE	BProtein/1/ABBR	BProtein/2	BProtein/2/LABEL	BProtein/2/ID	BProtein/2/NOTE	BProtein/2/ABBR

12	palatine tonsil	palatine tonsil	UBERON:0002373			primary nodular lymphoid tissue	primary lymphoid nodule of tonsil	UBERON:0010423
13	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil crypt	tonsil crypt	UBERON:0012181	No cells
14	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil capsule	tonsil capsule	UBERON:0005207
15	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil epithelium	tonsil epithelium	UBERON:0013696																							tonsil squamous cell	Tonsil squamous cell	CL:1001577																																																										CD90	THY1	HGNC:11801
16	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON																						T cell	T cell	CL:0000084																																																										CD3	CD3E	HGNC:1674			CD4	CD4	HGNC:1678
17	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON																						CD4 T cell	CD4-positive, alpha-beta T cell	CL:0000624																																																										CD3	CD3E	HGNC:1674			CD4	CD4	HGNC:1678
18	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON																						CD8 T cell	CD8-positive, alpha-beta T cell	CL:0000625																																																										CD3	CD3E	HGNC:1674			CD8	CD8A	HGNC:1706
19	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON																						fibroblast	Fibroblast	CL:0000057																																																										KRT7	KRT7	HGNC:6445			KRT8	KRT8	HGNC:6446
20	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON																						reticular cells	Reticular cell	CL:0000432																																																										KRT7	KRT7	HGNC:6445			KRT8	KRT8	HGNC:6446
21	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON																						B cell	B cell	CL:0000236																																																										CD19	CD19	HGNC:1633			CD20	MS4A1	HGNC:7315
22	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON																						dendritic cell	Dendritic Cell	CL:0000451																																																										CD11c	ITGAX	HGNC:6152			CD209	CD209	HGNC:1641
23	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON																						macrophage	Macrophage	CL:0000235																																																										CD14	CD14	HGNC:1628
24	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON																						plasma cell	Plasma Cell	CL:0000786																																																										CD138	SDC1	HGNC:10658			CD27	CD27	HGNC:11922
25	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON																						plasma cell	Plasma Cell	CL:0000786			plasma cell CD21			Not in CL																																																				CD39	ENTPD1	HGNC:3363			CD21	CR2	HGNC:2336
26	palatine tonsil	palatine tonsil	UBERON:0002373			blood vessel	blood vessel	UBERON:0001981			dorsal lingual artery	lingual artery	UBERON:0001610	Supply																	blood vessel endothelial cell	blood vessel endothelial cell	CL:0000071	used in blood vasculature ASCT+B							PECAM1	platelet and endothelial cell adhesion molecule 1	HGNC:8823																																																Alpha smooth muscle actin	Actin alpha smooth muscle	HGNC:130			CD31	PECAM1	HGNC:8823
27	palatine tonsil	palatine tonsil	UBERON:0002373			blood vessel	blood vessel	UBERON:0001981			ascending palatine artery	Ascending palatine artery	FMA:49555	Supply, not in Uberon																	blood vessel endothelial cell	blood vessel endothelial cell	CL:0000071	used in blood vasculature ASCT+B							PECAM1	platelet and endothelial cell adhesion molecule 1	HGNC:8823																																																Alpha smooth muscle actin	Actin alpha smooth muscle	HGNC:130			CD31	PECAM1	HGNC:8823
28	palatine tonsil	palatine tonsil	UBERON:0002373			blood vessel	blood vessel	UBERON:0001981			tonsillar branch of the facial artery	facial artery	UBERON:0001612	Supply																	blood vessel endothelial cell	blood vessel endothelial cell	CL:0000071	used in blood vasculature ASCT+B							PECAM1	platelet and endothelial cell adhesion molecule 1	HGNC:8823																																																Alpha smooth muscle actin	Actin alpha smooth muscle	HGNC:130			CD31	PECAM1	HGNC:8823
29	palatine tonsil	palatine tonsil	UBERON:0002373			blood vessel	blood vessel	UBERON:0001981			ascending pharyngeal artery	Ascending pharyngeal artery	FMA:49497	Supply, not in Uberon																	blood vessel endothelial cell	blood vessel endothelial cell	CL:0000071	used in blood vasculature ASCT+B							PECAM1	platelet and endothelial cell adhesion molecule 1	HGNC:8823																																																Alpha smooth muscle actin	Actin alpha smooth muscle	HGNC:130			CD31	PECAM1	HGNC:8823
30	palatine tonsil	palatine tonsil	UBERON:0002373			blood vessel	blood vessel	UBERON:0001981			lesser palatine artery	external carotid artery	UBERON:0001070	Supply																	blood vessel endothelial cell	blood vessel endothelial cell	CL:0000071	used in blood vasculature ASCT+B							PECAM1	platelet and endothelial cell adhesion molecule 1	HGNC:8823																																																Alpha smooth muscle actin	Actin alpha smooth muscle	HGNC:130			CD31	PECAM1	HGNC:8823
31	palatine tonsil	palatine tonsil	UBERON:0002373			blood vessel	blood vessel	UBERON:0001981			peritonsillar plexus of veins			Drain, not in Uberon, not in FMA																	blood vessel endothelial cell	blood vessel endothelial cell	CL:0000071	used in blood vasculature ASCT+B							PECAM1	platelet and endothelial cell adhesion molecule 1	HGNC:8823																																																Alpha smooth muscle actin	Actin alpha smooth muscle	HGNC:130			CD31	PECAM1	HGNC:8823
32	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON		tonsil T cell zone			Not in UBERON or FMA																	T cell	T cell	CL:0000084																																																										CD3	CD3E	HGNC:1674			CD4	CD4	HGNC:1678
33	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON		tonsil T cell zone			Not in UBERON or FMA																	CD4 T cell	CD4-positive alpha-beta T cells	CL:0000624																																																										CD3	CD3E	HGNC:1674			CD4	CD4	HGNC:1678
34	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON		tonsil T cell zone			Not in UBERON or FMA																	CD8 T cell	CD8-positive alpha-beta T cells	CL:0000625																																																										CD3	CD3E	HGNC:1674			CD8	CD8A	HGNC:1706
35	palatine tonsil	palatine tonsil	UBERON:0002373			diffuse lymphoid tissue	diffuse lymphoid tissue	FMA:55221	Not in UBERON		tonsil T cell zone			Not in UBERON or FMA																	dendritic cell	Dendritic Cell	CL:0000451																																																										CD11c	ITGAX	HGNC:6152			CD209	CD209	HGNC:1641
36	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA																	B cell	B cell	CL:0000236			Cycling B			not in CL		E2F8	E2F transcription factor 8	HGNC:24727			CDCA2	cell division cycle associated 2	HGNC:14623			NUGGC	nuclear GTPase, germinal center associated	HGNC:33550			CLSPN	claspin	HGNC:19715			ANLN	anillin, actin binding protein	HGNC:14082			MYBL1	MYB proto-oncogene like 1	HGNC:7547			FAM111B	FAM111 trypsin like peptidase B	HGNC:24200			KIF4A	kinesin family member 4A	HGNC:13339			NUF2	NUF2 component of NDC80 kinetochore complex	HGNC:14621			GTSE1	G2 and S-phase expressed 1	HGNC:13698			CD19	CD19	HGNC:1633			CD20	MS4A1	HGNC:7315
37	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA																	CD4 T cell	CD4-positive alpha-beta T cells	CL:0000624																																																										CD3	CD3E	HGNC:1674			CD4	CD4	HGNC:1678
38	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA																	regulatory T cell	regulatory T cell	CL:0000815								FOXP3	forkhead box P3	HGNC:6106																																																CD3	CD3E	HGNC:1674			CD4	CD4	HGNC:1678
39	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA																	B cell	B cell	CL:0000236																																																										CD19	CD19	HGNC:1633			CD20	MS4A1	HGNC:7315
40	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA																	plasma cell	Plasma Cell	CL:0000786																																																										CD138	SDC1	HGNC:10658			CD27	CD27	HGNC:11922
41	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA																	T Cell	T Cell	CL:0000084
42	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754													B cell	B cell	CL:0000236			Cycling B			not in CL		E2F8	E2F transcription factor 8	HGNC:24727			CDCA2	cell division cycle associated 2	HGNC:14623			NUGGC	nuclear GTPase, germinal center associated	HGNC:33550			CLSPN	claspin	HGNC:19715			ANLN	anillin, actin binding protein	HGNC:14082			MYBL1	MYB proto-oncogene like 1	HGNC:7547			FAM111B	FAM111 trypsin like peptidase B	HGNC:24200			KIF4A	kinesin family member 4A	HGNC:13339			NUF2	NUF2 component of NDC80 kinetochore complex	HGNC:14621			GTSE1	G2 and S-phase expressed 1	HGNC:13698			CD19	CD19	HGNC:1633			CD20	MS4A1	HGNC:7315
43	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754													CD4 T cell	CD4-positive alpha-beta T cells	CL:0000624																																																										CD3	CD3E	HGNC:1674			CD4	CD4	HGNC:1678
44	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754													regulatory T cell	regulatory T cell	CL:0000815								FOXP3	forkhead box P3	HGNC:6106																																																CD3	CD3E	HGNC:1674			CD4	CD4	HGNC:1678
45	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754													B cell	B cell	CL:0000236																																																										CD19	CD19	HGNC:1633			CD20	MS4A1	HGNC:7315
46	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754													plasma cell	Plasma Cell	CL:0000786																																																										CD138	SDC1	HGNC:10658			CD27	CD27	HGNC:11922
47	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754													T Cell	T Cell	CL:0000084
48	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754													macrophage	Macrophage	CL:0000235																																																										CD14	CD14	HGNC:1628
49	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754													germinal center B cell	germinal center B cell	CL:0000844																																																										CD14	CD14	HGNC:1628			CD19	CD19	HGNC:1633
50	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754													germinal center B cell	germinal center B cell	CL:0000844			germinal center B cell CD21			add to CL																																																				CD14	CD14	HGNC:1628			CD19	CD19	HGNC:1633
51	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		tonsil germinal center mantle zone			Not in UBERON or FMA												B cell	B cell	CL:0000236																																																										CD19	CD19	HGNC:1633			CD20	MS4A1	HGNC:7315
52	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		tonsil germinal center mantle zone			Not in UBERON or FMA												T cell	T cell	CL:0000084																																																										CD3	CD3E	HGNC:1674			CD4	CD4	HGNC:1678
53	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		tonsil germinal center mantle zone			Not in UBERON or FMA												macrophage	Macrophage	CL:0000235																																																										CD14	CD14	HGNC:1628
54	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754			tonsil germinal center	tonsil germinal center	UBERON:0013688								B cell	B cell	CL:0000236			Centroblast			(Adding new cell type)																																																				Ki67	MKI67	HGNC:7107
55	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754			tonsil germinal center	tonsil germinal center	UBERON:0013688								B cell	B cell	CL:0000236			Cycling B			not in CL		E2F8	E2F transcription factor 8	HGNC:24727			CDCA2	cell division cycle associated 2	HGNC:14623			NUGGC	nuclear GTPase, germinal center associated	HGNC:33550			CLSPN	claspin	HGNC:19715			ANLN	anillin, actin binding protein	HGNC:14082			MYBL1	MYB proto-oncogene like 1	HGNC:7547			FAM111B	FAM111 trypsin like peptidase B	HGNC:24200			KIF4A	kinesin family member 4A	HGNC:13339			NUF2	NUF2 component of NDC80 kinetochore complex	HGNC:14621			GTSE1	G2 and S-phase expressed 1	HGNC:13698			CD19	CD19	HGNC:1633			CD20	MS4A1	HGNC:7315
56	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754			tonsil germinal center	tonsil germinal center	UBERON:0013688								CD4 T cell	CD4-positive alpha-beta T cells	CL:0000624																																																										CD3	CD3E	HGNC:1674			CD4	CD4	HGNC:1678
57	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754			tonsil germinal center	tonsil germinal center	UBERON:0013688								regulatory T cell	regulatory T cell	CL:0000815								FOXP3	forkhead box P3	HGNC:6106																																																CD3	CD3E	HGNC:1674			CD4	CD4	HGNC:1678
58	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754			tonsil germinal center	tonsil germinal center	UBERON:0013688								B cell	B cell	CL:0000236																																																										CD19	CD19	HGNC:1633			CD20	MS4A1	HGNC:7315
59	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754			tonsil germinal center	tonsil germinal center	UBERON:0013688								plasma cell	Plasma Cell	CL:0000786																																																										CD138	SDC1	HGNC:10658			CD27	CD27	HGNC:11922
60	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754			tonsil germinal center	tonsil germinal center	UBERON:0013688								T Cell	T Cell	CL:0000084
61	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754			tonsil germinal center	tonsil germinal center	UBERON:0013688								macrophage	Macrophage	CL:0000235																																																										CD14	CD14	HGNC:1628
62	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754			tonsil germinal center	tonsil germinal center	UBERON:0013688								germinal center B cell	germinal center B cell	CL:0000844																																																										CD14	CD14	HGNC:1628			CD19	CD19	HGNC:1633
63	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754			tonsil germinal center	tonsil germinal center	UBERON:0013688								germinal center B cell	germinal center B cell	CL:0000844			germinal center B cell CD21			add to CL																																																				CD14	CD14	HGNC:1628			CD19	CD19	HGNC:1633
64	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754			tonsil germinal center	tonsil germinal center	UBERON:0013688			tonsil germinal center light zone			Not in UBERON or FMA
65	palatine tonsil	palatine tonsil	UBERON:0002373			tonsil follicle			Not in UBERON or FMA		tonsil secondary follicle			Not in UBERON or FMA		germinal center	germinal center	UBERON:0010754			tonsil germinal center	tonsil germinal center	UBERON:0013688			tonsil germinal center dark zone			Not in UBERON or FMA
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