Liver stage malaria activities of OSM-S-106 in Plasmodium berghei

	A	B	C	D	E	F	G	H	I	J	K	L	M	N	O	P	Q	R	S	T	U	V	W	X	Y	Z	AA	AB	AC	AD	AE	AF	AG	AH	AI	AJ	AK	AL	AM	AN	AO	AP	AQ	AR	AS	AT	AU	AV	AW	AX	AY
1	Project Director	Compound name	Batch #	MMV project code	Compound centralized (Specs)	Comments	Plate#	Result date	species tested	assay plate conc (uM)	assay tested	Parasite IC50 (uM)	STD Parasite IC50 or 95% Confidence Intervals	max % parasite inhibition (based on curve bottom)	HepG2 IC50 (uM)	STD HepG2 IC50 or 95% Confidence Intervals	max % HepG2 inhibition (based on curve bottom)	10	3.333333	1.111111	0.37037	0.123457	0.041152	0.013717	0.004572	0.001524	0.000508	0.000169	0.000056	10	3.333333	1.111111	0.37037	0.123457	0.041152	0.013717	0.004572	0.001524	0.000508	0.000169	0.000056	MW (g/mol) w/ salt	weight (mg)	mmols	Arrival date	Source	DMSO soluble	MW (g/mol) w/o salt	Note	chem. formula	Unsuccessful infection attempt
2	PW	OSM-S-106		MMV 11/0040	No	beige solid	MMVSM011	7-Jun-2013	P.berghei	10	Luciferase Envision	2.348	0.7453 to 7.396	98.87%	>10			0.01271926	0.20304449	0.8317206	1.40678699	1.05111133	1.16931105	1.4926917	1.21215576	1.39516079	1.43994319	1.10472104	1.31270087	0.01710316	0.26143101	1.01090463	1.31129871	1.4036431	1.30058017	1.51495106	1.41710999	1.19696757	1.51137821	1.59630207	1.69661665	306.36	3.77	12.30578404	30-May-13	University of Sydney, Dr Alice E Williamson			C12H10N4O2S2; beige powder
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5		ATQ (pos.CTRL)					MMVSM011	7-Jun-2013	P.berghei	10	Luciferase Envision	0.01381	0.008782 to 0.02173	99.44%	>10	(Very wide)		0.0033896	0.00211574	0.00459169	0.060785	0.2581613	0.27333996	0.39606098	0.74237108	0.86342353	0.95551812	1.11231037	0.86067845	0.00501044	-0.0007611	0.00604107	0.08801046	0.30959575	0.31948979	0.42021663	0.69223405	0.89519932	0.95758674	1.06800149	0.8321248
6		DMSO					MMVSM011	7-Jun-2013	P.berghei	10	Luciferase Envision	>10	0.0 to 1.489e+008		n/a			0.89695651	1.0075669	1.01994665	1.04397952	1.04586339	1.05926582	1.03157285	1.03456014	1.00891252	1.06661293	0.95885527	0.82590749	0.94910123	1.07360125	1.05398493	1.0915342	1.06429123	1.0887515	1.03550232	0.99407102	0.96748078	0.96909544	0.92628997	0.78629615
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