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Name of the PI / data ownerInstitutionDataset TypePlacental DomainImaging ModalityGestation StageMaternal or Fetal PathologyPlacental PathologyData Status and AvailabilityRepository Details or Estimated Release DateLinked Publications and FundingExtra Details
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Alys ClarkUniversity of AucklandStructural - Raw Images, Structural - Segmented Geometry, Structural - Surface or Volume MeshesDecidual spiral arteries and veinsmicro-CT1st TrimesterUnknown (first trimester)NoneNot Available - Acquisition or Curation StageEstimated release: mid-2018RSNZ Marsden GrantAim of this research is to quantify 3D spiral artery structure in the decidua and distribution of trophoblast in early gestation
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Alys ClarkUniversity of AucklandFunctional - Time SeriesTerminal villi and villous capillariesIn vitro transfer (vesicle, cell culture or explant), Time-lapse cell proliferation / migration data1st Trimester, 2nd Trimester, 3rd Trimester / TermNoneNoneNot Available - Pending PublicationEstimated release: mid-2018http://www.tandfonline.com/doi/abs/10.1080/19336918.2015.1083667;
RSNZ Marsden Fund
Cell migration and proliferation modelling to understand trophoblast migration and placental angiogenesis / vasculogenesis
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Bram Sengers & Rohan LewisUniversity of SouthamptonStructural - Raw Images, Structural - Segmented Geometry, Structural - Surface or Volume Meshes, Functional - Time SeriesTerminal villi and villous capillaries, Intervillous spaceConfocal, Ex vivo perfusion, In vitro transfer (vesicle, cell culture or explant)3rd Trimester / TermNoneNoneFreely Available (e.g. Creative Commons Attribution)Estimated release: November 2017
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Caitlin WyrwollUniversity of Western AustraliaStructural - Raw Images, Structural - Segmented Geometry, Structural - Surface or Volume MeshesRat feto-placental vascular castsmicro-CT3rd Trimester / TermRat model of growth restrictionNoneAvailable Upon Request (some rights reserved)DOI: 10.1007/s10237-017-0892-8
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Carolyn SalafiaPlacental Analytics LLCStructural - Raw Images, Structural - Segmented Geometry, Structural - Surface or Volume MeshesSubchorionic vessels and stem villi, Intermediate villi, Terminal villi and villous capillariesConfocal, Histology1st Trimester, 2nd Trimester, 3rd Trimester / TermFetal Growth Restriction (FGR / IUGR), Pre-eclampsia, Diabetes, Hypertension, Anaemia, Sickle-cellVelamentous / abnormal cord insertion, Placental thrombosis or lesions, Inflammation and/or infectionNot Available - Pending PublicationA large national archive of fixed placentas from normal and pathological pregnancies
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David EladTel Aviv UniversityFunctional - barrier transfer; Functional - soft tissue mechanicsAmniotic membranes; Uterine wallEx vivo perfusion; Ultrasound video recording3rd Trimester / Term; Non-pregnantNoneNoneAvailable Upon Request (some rights reserved)http://doi.org/10.1016/j.placenta.2013.03.014; http://doi.org/10.1016/j.placenta.2013.05.006Ultrasound video clips of non-pregnant uterine peristalsis
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David GrynspanCHEOStructural - Raw Images, Structural - Segmented Geometry, Structural - Surface or Volume Meshes, Functional - Time Series, Functional - Spatial MapsAmniotic membranes, Umbilical cord vessels, Subchorionic vessels and stem villi, Intermediate villi, Terminal villi and villous capillaries, Intervillous space, Decidual spiral arteries and veins, Myometrial and systemic vesselsStandard H & E histology1st Trimester, 2nd Trimester, 3rd Trimester / TermNone, Fetal Growth Restriction (FGR / IUGR), Stillbirth, Pre-eclampsia, Diabetes, Hypertension, Anaemia, Sickle-cellVelamentous / abnormal cord insertion, Placental thrombosis or lesions, Inflammation and/or infection, Infracts, Villous abnormaitiesAvailable Upon Request (some rights reserved)
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Graham BurtonUniversity of CambridgeStructural - Raw Imagesplacenta-in-situ specimensTiled high-resolution flat-bed scanner1st Trimester, 2nd Trimester, 3rd Trimester / TermNone; mostly unknownNone or unknown; Low-lying placentas; Ante-partum haemorrhageFreely Available (e.g. Creative Commons Attribution)https://www.trophoblast.cam.ac.uk/Resources/boyd-collectionPathology of the Human Placenta (http://www.springer.com/gb/book/9783642239403)The unique Boyd Collection is comprised solely of histological sections of specimens that local pathologists sent Professor Boyd for review
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Henning SchneiderUniversity of Bern; Institute of Biochemistry and Molecular Medicine Structural - Raw Images, Functional - Time SeriesSubchorionic vessels and stem villi, Intermediate villi, Terminal villi and villous capillaries, Intervillous space, Decidual spiral arteries and veinsEx vivo perfusion3rd Trimester / TermPre-eclampsiaNoneFreely Available (e.g. Creative Commons Attribution)http://dx.doi.org/10.1016/j.placenta.2014.11.022; Funding: German Research Foundation, Swiss Research Council, NIH, et al.Ex vivo functional data published over 45 years; digitised material from rare (including non-English) publications
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Igor ChernyavskyUniversity of ManchesterStructural - Raw Images, Structural - Segmented Geometry, Structural - Surface or Volume Meshes, Functional - Time Series, Functional - Spatial MapsTerminal villi and villous capillaries, Intervillous spaceConfocal, Light-Sheet, micro-CT, Ex vivo perfusion, Oxygen sampling3rd Trimester / TermNone, Fetal Growth Restriction (FGR / IUGR)NoneAvailable Upon Request (some rights reserved)University of Manchester Research Data Storagehttp://doi.org/10.1371/journal.pone.0165369;
Funded by MRC NIRG: http://gtr.rcuk.ac.uk/projects?ref=MR/N011538/1
Image-based oxygen transfer modelling; developing new diagnostic indices; stratification of FGR pathologies at structural and functional level
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Mary RutherfordKing's College LondonStructural - Raw Images, Functional - Time Series, Functional - Spatial MapsWhole organMRI2nd Trimester, 3rd Trimester / TermNone, Fetal Growth Restriction (FGR / IUGR), Pre-eclampsia, Hypertension, ObesityNoneAvailable Upon Request (some rights reserved)NIH-funded placenta imaging project (www.placentaimagingproject.org)
https://projectreporter.nih.gov/project_info_description.cfm?aid=9076542
Multi-modal aquisition on around 30 subjects to quantify placental structure and micro-structure (T1-, T2-weighted and diffusion MRI) and oxygenation (multi-echo gradient-echo T2* scans)
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Romina Plitman & Michelle OyenUniversity of CambridgeStructural - Raw Images, Structural - Segmented Geometry, Structural - Surface or Volume MeshesTerminal villi and villous capillariesConfocal3rd Trimester / TermNoneNoneAvailable Upon Request (some rights reserved)https://doi.org/10.1016/j.placenta.2016.05.001, https://doi.org/10.1016/j.jbiomech.2016.10.001
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Parisa MirbodClarkson UniversityStructural - Raw Images, Structural - Surface or Volume MeshesSubchorionic vessels and stem villimicro-CT3rd Trimester / TermNoneNoneAvailable Upon Request (some rights reserved)
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Penny GowlandUniversity of NottinghamFunctional - Time Series, Functional - Spatial MapsWhole organMRI2nd Trimester, 3rd Trimester / TermNone, Fetal Growth Restriction (FGR / IUGR), Pre-eclampsiaNone or UnknownAvailable Upon Request (some rights reserved)Any time as it is likely that there will be no conflict in planned publishingNIH funding
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Rohan LewisUniversity of SouthamptonStructural - Raw Images, Structural - Segmented GeometrySubchorionic vessels and stem villi, Intermediate villi, Terminal villi and villous capillaries, Intervillous spaceElectron, Confocal, Light-Sheet, micro-CT3rd Trimester / TermNoneNoneAvailable Upon Request (some rights reserved)
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Carolyn JonesUniversity of ManchesterStructural - Raw ImagesAmniotic membranes, Intermediate villi, Terminal villi and villous capillaries, Intervillous spaceElectron1st Trimester, 2nd Trimester, 3rd Trimester / TermNone, Fetal Growth Restriction (FGR / IUGR), Pre-eclampsia, Diabetes, HypertensionNoneAvailable Upon Request (some rights reserved)A large physical archive of resin-embedded blocks is stored at the Univerity of Manchester, St Mary's Research Centre PMID: 1873486, PMID: 7279874, PMID: 7443636, PMID: 745024, PMID: 151973, PMID: 757226, PMID: 591426, PMID: 844087, PMID: 948370, PMID: 932880, PMID: 1263021, PMID: 21196697, PMID: 8311922, PMID: 8290491, PMID: 2822737, PMID: 2414769, PMID: 2127960, PMID: 7767634, PMID: 11286564, DOI: 10.1016/j.placenta.2007.11.004These publications on placental ultrastructure are associated with a large archive of resin-embedded blocks of placenta from normal and pathological pregnancies and some wax blocks from the same patients. They were all fixed immediately after delivery in the 1970's when this was possible.
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