ABCDEFGHIJ
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EAGLE working group Cognition and Behaviour
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Phenotype Ia: externalizing behaviour
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CohortGWA data available at the 1st of March 2010phenotypeother related phenotypes:
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n (platform)externalizing behaviour
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instrument informant*age **no. of assessments
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Generation R, Rotterdamcaucasian 2661 (illumina 610k)CBCL P0-4, 5 (by 2010)3
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ALSPACcaucasian 3000 (Illumina 317k + 610k)SDQ P4-136
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Rutter P0-41
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Western Australian Preganacy Cohort (Raine) study caucasian 1200 (illumina 660k)TTSP11
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CBCL P,S,T0-186,2,2
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SDQ P101
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1958BCcaucasian 1500 (illumina 500k + affy 550k)Bristol soc adjT7,112
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caucasian 2500 (illumina 500k)Rutter 161
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caucasian 3000 (affy v.6.0 + illumina 1.2M)
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Note: there is overlap between samples, total ~5500)
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MoBa 0CBCL (11 items at 18 mo, 13 items at 36 mo)P0-42Social interactionASQ (3 items at 6 mo, 6 items at 18 mo)P0-4
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ITSEA (9 items at 36 mo)P0-41TemperamentEAS (3 items at 6 mo, 11 items at 18 mo, 12 items at 36 mo)P0-4
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SDQ (5 items at 36 mo)P0-41TemperamentICQ (8 items at 6 mo)P0-4
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Autistic traitsESAT (18 mo) P0-4
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Autistic traitsMCHAT (Full version (23 items) at 18 mo, 7 items at 36 mo)P0-4
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SCQ 36 moP0-4
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Eating behaviorsCFQ (12 items at 36 mo)P0-4
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Autistic traitsADI-R (36-42 mo)P - ABC study0-4
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Autistic traitsADOS (36-42 mo)O - ABC study0-4
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Executive functionBRIEF-P (36-42 mo)P+T - ABC and ADHD studies0-4
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TemperamentCBQ (36-42 mo)P - ABC and ADHD studies0-4
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LISA775 (Affymetrix 5.0 and 6.0)SDQP10-18?
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HBCScaucasian 1500 (Illumina 610k) OABCLS63-73
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YNTRcaucasian 2125 (Affymetrix 6.0)CBCLP3,7,10,124
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YSRS14, 16, 183
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DevereuxP51
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abbreviations:
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CBCLchild behaviour checklist
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TTSToddler Temprament Scale
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SDQStrength and Difficulties Questionnaire
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BDIBeck's Depression Inventory
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MoBaThe Norwegian Mother and Child Cohort study (108,000 children included)
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ABCThe Autism Birth Cohort study, a MoBa sub-study (600 children included, will eventually include 1,500-2,000)
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ADHDThe ADHD study, a MoBa substudy (700 included, will eventually include ca. 2,000)
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ASQAges and Stages Questionnaire
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EASEmotional Availability Scale
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ICQInfant Characteristic Questionnaire
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ESATEarly Screening for Autistic Traits
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MCHATModified Checklist for Autism in Toddlers
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CBCLChild Behavior Checklist
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SCQSocial Communication Questionnaire
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ITSEAInfant-Toddler Social and Emotional Assessment
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CFQChild Feeding Questionnaire
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SDQStrengths and Difficulties Questionnaire
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ADI-RAutism Diagnostic Interview - Revised
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ADOSAutism Diagnostic Observation Schedule
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BRIEF-PBehavior Rating Inventory of Executive Function - Preschool Version
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CBQChildren's Behavior Questionnaire
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YSRYouth Self Report
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* informant:
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self=S, parent=P, teacher=T, observed=O
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** age:
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0-4yrs, 5-9yrs, 10-18yrs.
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OABCLOlder Adult Behavior Checklist(Aachenbach)
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