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1 | GiveWell estimates of expected increases in immunization coverage for New Incentives coverage monitoring | |||||||||||||||||||||||||
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3 | Survey plans in Katsina and Jigawa states | |||||||||||||||||||||||||
4 | Baseline survey, Katsina and Jigawa | September 2021 | ||||||||||||||||||||||||
5 | Age group for surveys | 6-12 months | ||||||||||||||||||||||||
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7 | Characteristics of survey cohort at 12-month follow up | |||||||||||||||||||||||||
8 | Proposed timing of 12-month follow up | September 2022 | ||||||||||||||||||||||||
9 | % of expansion LGAs where NI will start operation in November 2021 | 50% | ||||||||||||||||||||||||
10 | % of expansion LGAs where NI will start operation in January 2022 | 50% | ||||||||||||||||||||||||
11 | % of survey age range at 12-month follow up born after start of program, November group | 67% | ||||||||||||||||||||||||
12 | % of survey age range at 12-month follow up born after start of program, January group | 33% | ||||||||||||||||||||||||
13 | % of survey age range at 12-month follow up born after program ramp-up (6 months of operations) | 0% | ||||||||||||||||||||||||
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15 | Characteristics of survey cohort at 18-month follow up | |||||||||||||||||||||||||
16 | Proposed timing of 18-month follow up | March 2023 | ||||||||||||||||||||||||
17 | % of survey age range born after program start | 100% | ||||||||||||||||||||||||
18 | % of survey age range born after program ramp-up (6 months of operations), November group | 67% | ||||||||||||||||||||||||
19 | % of survey age range at born after program ramp-up (6 months of operations), January group | 33% | ||||||||||||||||||||||||
20 | Average % of survey age range born after program ramp-up (6 months of operations) | 50% | ||||||||||||||||||||||||
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22 | Characteristics of survey cohort at 24-month follow up | |||||||||||||||||||||||||
23 | Proposed timing of 24-month follow up | September 2023 | ||||||||||||||||||||||||
24 | % of survey age range at 24-month follow up born after program start | 100% | ||||||||||||||||||||||||
25 | % of survey age range at 24-month follow up born after program ramp-up (6 months of operations) | 100% | ||||||||||||||||||||||||
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27 | RCT inputs | |||||||||||||||||||||||||
28 | RCT effect size, BCG (pp increase) | 0.16 | Based on unadjusted self-reported immunization rates | |||||||||||||||||||||||
29 | RCT effect size, Penta 1 and associated vaccines (pp increase) | 0.21 | ||||||||||||||||||||||||
30 | RCT effect size, Measles 1 (pp increase) | 0.14 | ||||||||||||||||||||||||
31 | % control group receiving BCG within +/- 1 month of recommended age | 0.66 | Children who received BCG outside of New Incentives aren't eligible for enrollment into New Incentives and receiving incentives for later vaccines. | |||||||||||||||||||||||
32 | % control group receiving Penta 1 within +/- 1 month of recommended age | 0.68 | ||||||||||||||||||||||||
33 | % control group receiving Measles 1 within +/- 1 month of recommended age | 0.53 | ||||||||||||||||||||||||
34 | Recommended age for BCG (months) | 0 | ||||||||||||||||||||||||
35 | Recommended age for Penta 1 and associated vaccines (months) | 1.5 | ||||||||||||||||||||||||
36 | Recommended age for Measles 1 (months) | 9 | ||||||||||||||||||||||||
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38 | What effect size (increase in vaccination coverage since baseline) do we expect at the 12-month follow up? | |||||||||||||||||||||||||
39 | 1. Effect size for survey cohort born after the start of the program | |||||||||||||||||||||||||
40 | Ramp-up adjustment: how much is the effect attenuated in the first 6 months due to program ramp-up? | 25% | A guess. New Incentives' program takes ~6 months to fully ramp up, and it's unlikely to reach its full potential impact during this period. | |||||||||||||||||||||||
41 | % of group born before program is fully ramped up | 100% | ||||||||||||||||||||||||
42 | Estimated effect size for BCG, group born after NI start (pp increase) | 0.12 | Based on adjusted RCT results | |||||||||||||||||||||||
43 | Estimated effect size for Penta 1 and associated vaccines, group born after NI start (pp increase) | 0.16 | Based on adjusted RCT results | |||||||||||||||||||||||
44 | Estimated effect size for Measles 1, group born after NI start (pp increase) | 0.11 | Based on adjusted RCT results; no adjustments for differences in timely vaccination | |||||||||||||||||||||||
45 | Average estimated effect size across vaccines, group born after NI start (pp increase) | 0.13 | ||||||||||||||||||||||||
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47 | 2. Effect size for survey cohort with partial exposure to New Incentives' program | |||||||||||||||||||||||||
48 | Month of life for partially exposed survey group when New Incentives' programs starts | 1-4 months | ||||||||||||||||||||||||
49 | Percent of the population that remains unvaccinated for BCG when New Incentives' program begins and is thus eligible for program enrollment | 53% | ||||||||||||||||||||||||
50 | Adjustment to account for those who delay vaccination being more likely to respond to the incentive | 1.5 | An uncertain guess. It seems likely that always-takers are more likely to be vaccinated on schedule, and that relatively more incentive-driven households may remain eligible for NI at the program start date, making attenuation of the effect size less than proportional to the ineligible % of the population. | |||||||||||||||||||||||
51 | Adjusted multiplier on potential effect sizes for partially exposed survey group | 80% | ||||||||||||||||||||||||
52 | Estimated effect size for BCG, partially exposed survey group (pp increase) | 0.10 | ||||||||||||||||||||||||
53 | Estimated effect size for Penta 1 and associated vaccines, partially exposed survey group (pp increase) | 0.13 | ||||||||||||||||||||||||
54 | Estimated effect size for Measles 1, partially exposed survey group (pp increase) | 0.08 | ||||||||||||||||||||||||
55 | Average estimated effect size across vaccines, partially exposed survey group (pp increase) | 0.10 | ||||||||||||||||||||||||
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57 | Expected effect sizes at 12-month follow up: combined across entire survey age range | |||||||||||||||||||||||||
58 | Percentage of survey group born before the program started | 50% | ||||||||||||||||||||||||
59 | Percentage of survey group born since the program started | 50% | ||||||||||||||||||||||||
60 | Estimated effect size for BCG at 12-month follow up (pp increase) | 10.8% | ||||||||||||||||||||||||
61 | Estimated effect size for Penta 1 and associated vaccines at 12-month follow up (pp increase) | 14.2% | ||||||||||||||||||||||||
62 | Estimated effect size for Measles 1 at 12-month follow up (pp increase) | 9.5% | ||||||||||||||||||||||||
63 | Average estimated effect size across vaccines at 12-month follow up (pp increase) | 11.5% | ||||||||||||||||||||||||
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65 | What effect size could we expect to obtain on vaccinations at 18-month follow up? | |||||||||||||||||||||||||
66 | % of survey age range at 18-month follow up born after the program starts | 100% | ||||||||||||||||||||||||
67 | Average % of survey age range at 18-month follow up born after program ramp-up (6 months of operations) | 50% | ||||||||||||||||||||||||
68 | Ramp-up adjustment: how much is the effect attenuated in the first 6 months due to program ramp-up? | 25% | ||||||||||||||||||||||||
69 | Estimated effect size for BCG at 18-month follow up (pp increase) | 14.0% | ||||||||||||||||||||||||
70 | Estimated effect size for Penta 1 and associated vaccines at 18-month follow up (pp increase) | 18.4% | ||||||||||||||||||||||||
71 | Estimated effect size for Measles 1 at 18-month follow up (pp increase) | 12.3% | ||||||||||||||||||||||||
72 | Average estimated effect size across vaccines at 18-month follow up (pp increase) | 14.9% | ||||||||||||||||||||||||
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74 | What effect size could we expect to obtain on vaccinations at 24-month follow up? | |||||||||||||||||||||||||
75 | % of survey age range at 24-month follow up born after the program starts | 100% | ||||||||||||||||||||||||
76 | Average % of survey age range at 24-month follow up born after program ramp-up (6 months of operations) | 100% | ||||||||||||||||||||||||
77 | Estimated effect size for BCG at 24-month follow up (pp increase) | 16.0% | ||||||||||||||||||||||||
78 | Estimated effect size for Penta 1 and associated vaccines at 24-month follow up (pp increase) | 21.0% | ||||||||||||||||||||||||
79 | Estimated effect size for Measles 1 at 24-month follow up (pp increase) | 14.0% | ||||||||||||||||||||||||
80 | Average estimated effect size across vaccines at 24-month follow up (pp increase) | 17.0% | ||||||||||||||||||||||||
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