48 drug features

	A	B	C	D	E
1	Feature	Feature Type	KS - pvalue	KS - D statistic	Description
2	Molecular Weight	Chemical	6,30E-05	2,417	Proposed by Lipinski as relevant to drug-likeness
3	XLogP	Chemical	6,98E-01	751	Octanol-water partitition coeffecient log P, proposed by Lipinski as relevant to drug-likeness
4	Hydrogen Bond Donor Count	Chemical	1,61E-04	2,305	Proposed by Lipinski as relevant to drug-likeness
5	Hydrogen Bond Acceptor Count	Chemical	9,94E-02	1,301	Proposed by Lipinski as relevant to drug-likeness
6	Polar Surface Area	Chemical	2,18E-01	1,118	Proposed by Ghose, Veber and QED metric as relevant to drug-likeness
7	Formal Charge	Chemical	9,94E-01	447	Formal charge of the compound
8	Number of Rings	Chemical	3,68E-02	1,501	Number of rings of the compound
9	Rotatable Bond Count	Chemical	5,58E-02	1,421	Proposed by Veber and QED metric as relevant to drug-likeness
10	Refractivity	Chemical	4,45E-01	917	Proposed by Ghose as relevant to drug-likeness
11	ALogP Solubility	Chemical	1,01E-01	1,306	Proposed by QED metric as relevant to drug-likeness
12	Ro5	Chemical Rule	6,91E-01	756	Pass/Fail outcome computed from Lipinski's rule of 5 (Ro5)
13	Ghose	Chemical Rule	2,37E-01	1,096	Pass/Fail outcome computed from the Ghose rule
14	Veber	Chemical Rule	1,33E-02	1,681	Pass/Fail outcome computed from the Veber rule
15	QED	Chemical Rule	1,99E-02	1,622	The unweighted version of the Quantitative Estimate for Drug-likeness (QED) metric
16	Loss of Function Frequency	Target-based	4,98E-02	1,461	Loss of function frequency for the drug's target, calculated using the ExAC database
17	Network betweenness	Target-based	1,75E-01	1,171	Network betweenness of the drug's target
18	Network degree	Target-based	1,85E-01	1,158	Network degree of the drug's target
19	PC1 - Expression	Target-based	2,75E-10	35,781	Principle Component 1 for PCA of GTEx tissue data
20	PC2 - Expression	Target-based	3,12E-01	10,224	Principle Component 2 for PCA of GTEx tissue data
21	PC3 - Expression	Target-based	4,71E-01	89,898	Principle Component 3 for PCA of GTEx tissue data
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