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case fatality rate noteaverage basic reproductive rate primary mode of transmission survival time on surfacessurvival in ideal conditions (ie. blood, faeces)notepathogen typeinfectious doseaverage incubation periodviral load in acute stageyearly fatalitiesyearly fatalitiesyearly fatalitieslower R0upper R0survival time on surfaces, room temp (hours)lowerinfectious dose second sourceinfectious dose third sourcenotesourceshttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/index-eng.php#vyearly fatalitieshttp://www.who.int/healthinfo/global_burden_disease/estimates/en/index1.htmlhttp://www.cdc.gov/mmwr/PDF/wk/mm6153.pdfhttp://en.wikipedia.org/wiki/Human_mortality_from_H5N1
individual links given in hidden columns to right, where different
infectious dose
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grey = not plottedhealthy adultalso known as "R0"daysdayspathogen particles required to infect
(* = animal dose)
daysvirus particles / 1mLWorld, roundedUS, roundedAfrica, roundedhttp://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1002512http://www.phidias.us/hazard/query/query_detail.php?c_hazard_ID=67
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Anthrax (untreated)20%6.5airborne70 years!bacterium100,000-0-20,250https://www.google.com/search?sourceid=chrome-psyapi2&ion=1&espv=2&ie=UTF-8&q=anthrax%20case%20fatality%20ratehttps://www.ll.mit.edu/publications/journal/pdf/vol17_no1/17_1_6Jamrog.pdfhttp://en.wikipedia.org/wiki/Infectious_dose
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Bird Flu (H5N1)60%1airborne droplet235virusunknown1803146http://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1http://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/influenza-a-eng.phphttp://www.nature.com/srep/2013/130710/srep02175/full/srep02175.htmlhttps://microbewiki.kenyon.edu/index.php/H5N1_Influenza_A
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Bubonic Plague (untreated)
60%1bites3100human bloodbacterium100-0-7210-40,000,000http://en.wikipedia.org/wiki/List_of_human_disease_case_fatality_rateshttp://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0008401http://www.cdc.gov/biosafety/publications/bmbl5/BMBL5_sect_VIII_a.pdf
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C.Difficile24%1.25fecal-oral6090bacterium<100-7,300-0.52http://wwwnc.cdc.gov/eid/article/18/2/10-1611_articlehttp://www.nhs.uk/chq/Pages/how-long-do-bacteria-and-viruses-live-outside-the-body.aspxhttp://www.ncbi.nlm.nih.gov/pubmed/21558767http://wwwnc.cdc.gov/eid/article/15/5/08-1186_articlehttp://www.bio-protocol.org/e1002
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Campylobacter1.20%0.19food0.628in cold water, animal R0 figurebacterium500-4,000-550http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236927/http://www.nhs.uk/chq/Pages/how-long-do-bacteria-and-viruses-live-outside-the-body.aspxhttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/campylobacter-coli-eng.phphttp://www.mssanz.org.au/modsim2011/B2/parshotam.pdfhttp://wwwnc.cdc.gov/travel/yellowbook/2014/chapter-3-infectious-diseases-related-to-travel/campylobacteriosis
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Chicken Pox0.00%8.5airborne droplet0.22virusunknown100,000,000-16-7104http://en.wikipedia.org/wiki/List_of_human_disease_case_fatality_rateshttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/var-zo-eng.phphttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/var-zo-eng.phphttp://www.msdsonline.com/resources/msds-resources/free-safety-data-sheet-index/varicella-zoster-virus.aspxhttp://jcm.asm.org/content/38/6/2447/F1.expansion.htmlhttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/var-zo-eng.php
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Cholera1.63%2.13bacterium1,000,00094,000055,0001.632.6333,334,000,000infectious dose is serotypes O139, O1http://www.who.int/gho/epidemic_diseases/cholera/case_fatality_rate/en/http://www.nature.com/srep/2013/130110/srep00997/full/srep00997.htmlhttp://en.wikipedia.org/wiki/Infectious_dose
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Dengue Fever5%3bitesvirusunknown29,00011,900http://www.idpjournal.com/content/3/1/12http://www.cdc.gov/dengue/faqFacts/fact.htmlhttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/msds50e-eng.php
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Zika0%3bitesinfectiousness similar to "Dengue"virus000http://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/msds50e-eng.php
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Diphtheria7.50%6.5body fluidsbacteriumunknown2,60001,70067http://www.cdc.gov/diphtheria/clinicians.htmlhttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/msds51e-eng.php
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E.coli4%1.15fecal-oral12infectious dose varies in different strains, can be as low as 10-100 organismsbacterium100,000,000260,000100103,0000.32~50,500,000http://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/escherichia-coli-eng.php#footnote14http://aem.asm.org/content/69/7/3687http://www.who.int/mediacentre/factsheets/fs125/en/http://www.mssanz.org.au/modsim2011/B2/parshotam.pdfhttp://en.wikipedia.org/wiki/Infectious_dose
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Ebola50%2.5body fluids0.51487 day survival in semenvirus550,000,000,0004,55514,55414http://www.who.int/mediacentre/factsheets/fs103/en/http://www.cdc.gov/vhf/ebola/transmission/qas.htmlhttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/ebola-eng.phphttp://en.wikipedia.org/wiki/Basic_reproduction_numberhttp://www.who.int/mediacentre/factsheets/fs103/en/http://currents.plos.org/outbreaks/article/estimating-the-reproduction-number-of-zaire-ebolavirus-ebov-during-the-2014-outbreak-in-west-africa/http://www.nytimes.com/2014/10/14/us/questions-rise-on-preparations-at-hospitals-to-deal-with-ebola.html?_r=0https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&ved=0CB8QFjAA&url=http%3A%2F%2Fwww.phac-aspc.gc.ca%2Flab-bio%2Fres%2Fpsds-ftss%2Febola-eng.php&ei=KSJEVI_mCqPg7QaIooDgBg&usg=AFQjCNEiBmo7OAsASyqJsRY3QzjgQr2NjA&sig2=JvZD-hqLKkrlbH-lA6i-3A
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Hand, Foot and Mouth
0.06%3.50body fluids14.0150soil, R0 = averge across virus typesvirus18212http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050796/http://wwwnc.cdc.gov/eid/article/9/1/02-0112_articlehttp://www.antimicrobialtestlaboratories.com/coxsackievirus.htmhttp://www.oie.int/doc/ged/D8191.PDF
http://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/msds44e-eng.php
http://www.who.int/water_sanitation_health/bathing/recreadischap6.pdf
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Hepatitis B0.75%4.04body fluids0.77virus'extraordinarily small'12,500,000150,0001,80018,6001.456.6216http://www.cdc.gov/vaccines/pubs/surv-manual/chpt04-hepb.pdfhttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/hepatitis-b-eng.phphttp://www.ncbi.nlm.nih.gov/pubmed/21040731http://link.springer.com/article/10.1007%2Fs00477-013-0776-0#page-1http://www.nytimes.com/2014/10/14/us/questions-rise-on-preparations-at-hospitals-to-deal-with-ebola.html?_r=0http://infectionnet.org/notes/hepatitis-viruses/
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HIV (treated)2.10%3.5sexual contact715virus1-6500075,0001,500,0008,4001,090,00025750% infective dose 1 virion (min) to 65,000http://www.aidsmap.com/Wide-variations-between-US-states-in-HIV-mortality-rates/page/2117475/http://www.aidsmap.com/Survival-outside-the-body/page/1321278/http://www.bmj.com/rapid-response/2011/11/01/hiv-survival-outside-bodyhttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/hiv-vih-eng.phphttp://en.wikipedia.org/wiki/Basic_reproduction_number
http://www.academia.edu/1746565/Epidemiologic_Concepts_for_the_Prevention_and_Control_of_Infectious_Diseases
http://www.nytimes.com/2014/10/14/us/questions-rise-on-preparations-at-hospitals-to-deal-with-ebola.html?_r=0
http://www.ncbi.nlm.nih.gov/pubmed/19948896
http://pathmicro.med.sc.edu/lecture/hiv3.htm
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HIV (untreated)80%3.5sexual contact715virus1-650001,500,0008,4001,090,00025750% infective dose 1 virion (min) to 65,000http://www.aidsmap.com/Survival-outside-the-body/page/1321278/http://www.bmj.com/rapid-response/2011/11/01/hiv-survival-outside-bodyhttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/hiv-vih-eng.phphttp://en.wikipedia.org/wiki/Basic_reproduction_numberhttp://www.academia.edu/1746565/Epidemiologic_Concepts_for_the_Prevention_and_Control_of_Infectious_Diseaseshttp://www.ncbi.nlm.nih.gov/pubmed/19948896
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Influenza Pandemic 1918
2.50%3airborne dropletvirus5.6
75,000,000 (1918-19)
650,000 (1918-19)
-1.82https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&ved=0CCgQFjAA&url=http%3A%2F%2Fcis.uchicago.edu%2Foutreach%2Fsummerinstitute%2Fepidemics%2Fpresentations%2FWeber.ppt&ei=b5U3VNP_DoTP7gb6joGwDQ&usg=AFQjCNFw3QCdUNXC11CgV8_D__3LyaGt5w&sig2=dfHcL3cMQqk-P8xOJqUTrghttp://wwwnc.cdc.gov/eid/article/12/1/05-0979_articlehttp://wwwnc.cdc.gov/eid/article/12/11/06-0426_articlehttps://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=6&ved=0CE4QFjAF&url=http%3A%2F%2Fwww.mdpi.com%2F1999-4915%2F2%2F8%2F1530%2Fpdf&ei=PvBEVKO5Hcau7Abyy4GADw&usg=AFQjCNGSB-f7wflPOcjC933IbtZwfvUtPA&sig2=rCX6dQtdVhSGXsBFXF-VIQ
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Lyme Disease0.20%4.4bitesbacterium50000*-10-3.85http://izt.ciens.ucv.ve/ecologia/Archivos/ECO_POB%202008/ECOPO6_2008/Hartemink%20y%20col%202008.pdfhttp://www.cdc.gov/anaplasmosis/stats/http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0101009
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Malaria (P. falciparum)
0.50%80bites0~parasite1 to 10620,00010550,000infectious dose for unspecified malaria strainhttp://www.malariajournal.com/content/11/1/19http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.0050042http://ocw.jhsph.edu/courses/publichealthbiology/PDFs/Lecture2.pdfhttp://www.malariasite.com/malaria/Transmission.htm
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Malaria (P. malariae)0.50%16bites0~parasite1 to 10620,00010550,000infectious dose for unspecified malaria strainhttp://www.malariajournal.com/content/11/1/19http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.0050042http://ocw.jhsph.edu/courses/publichealthbiology/PDFs/Lecture2.pdfhttp://www.malariasite.com/malaria/Transmission.htm
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Measles0.30%15airborne0.1-virus10,000130,000248,00012182http://en.wikipedia.org/wiki/Measleshttp://www.cdc.gov/measles/about/transmission.htmlhttp://en.wikipedia.org/wiki/Basic_reproduction_numberhttp://www.biomedcentral.com/1741-7015/7/16
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MERS45%0.5airborne droplet25virusunknown17002http://en.wikipedia.org/wiki/List_of_human_disease_case_fatality_rateshttp://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20590http://www.sciencedirect.com/science/article/pii/S120197121401491Xhttp://www.ehs.colostate.edu/WOHSP/Illness_Policy_Info_Emergency_Response_Packets/Agent_Fact_Sheets/Middle_East_Respiratory_Syndrome_Virus_Fact_Sheet.pdf
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MRSA20%1.625surfaces742bacterium100,000-11,000-0.25338100,000http://www.medicinenet.com/mrsa_infection/page7.htmhttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/staphylococcus-aureus-eng.phphttp://www.crd.york.ac.uk/crdweb/ShowRecord.asp?ID=22010001059#.VDeZP9R4q5whttps://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=9&ved=0CFsQFjAI&url=http%3A%2F%2Fwww.phac-aspc.gc.ca%2Flab-bio%2Fres%2Fpsds-ftss%2Fstaphylococcus-aureus-eng.php&ei=KSJEVI_mCqPg7QaIooDgBg&usg=AFQjCNG5JOHXYqZwCmKvVZ8zVdxFT69ROg&sig2=47gsLPgoNtv49wVRWGlUqA
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Mumps1%12.5airborne dropletvirus--1-1114http://ocw.jhsph.edu/courses/publichealthbiology/PDFs/Lecture2.pdfhttp://www.health.gov.au/internet/immunise/publishing.nsf/content/handbook10-4-11
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Norovirus0.01%2surfaces1228virus18-1000150,00069060,000http://wwwnc.cdc.gov/eid/article/19/8/13-0465_articlehttp://www.cdc.gov/hicpac/norovirus/tables/evidence-table-q3-ron.htmlhttp://wwwnc.cdc.gov/eid/article/19/8/13-0472-t3http://www.cdc.gov/mmwr/preview/mmwrhtml/rr6003a1.htm
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Pertussis (Whooping Cough)
4%14.5airborne dropletdeath rate in infantsbacterium<10067,0002637,0001217200http://www.who.int/immunization/monitoring_surveillance/burden/vpd/surveillance_type/passive/pertussis_standards/en/http://en.wikipedia.org/wiki/Basic_reproduction_numberhttps://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=23&ved=0CMUBEBYwFg&url=http%3A%2F%2Fwww.phac-aspc.gc.ca%2Flab-bio%2Fres%2Fpsds-ftss%2Fbordetella-pertussis-eng.php&ei=KSJEVI_mCqPg7QaIooDgBg&usg=AFQjCNFEMnwoU5HbhHgLtrfXp7JJxY6zfA&sig2=t9soKF3TSHfUWcMOLbNnRQhttp://www.jove.com/visualize/abstract/24227794/resident-microbiota-affect-bordetella-pertussis-infectious-dose-hosthttp://microbewiki.kenyon.edu/index.php/Haemophilus_pertussis_(Whooping_Cough)#Infectious_dose.2C_incubation.2C_and_colonization
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Pneumonic Plague (untreated)
100%3.2airborne droplet3100bacterium10,000,000,000-0-72https://public.health.oregon.gov/DiseasesConditions/CommunicableDisease/ReportingCommunicableDisease/ReportingGuidelines/Documents/plague.pdfhttp://www.researchgate.net/publication/6993284_Transmission_potential_of_primary_pneumonic_plague_time_inhomogeneous_evaluation_based_on_historical_documents_of_the_transmission_networkhttp://www.cfsph.iastate.edu/Factsheets/pdfs/plague.pdfhttp://microbewiki.kenyon.edu/index.php/Yersinia_pseudotuberculosis_infection
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Polio22%6fecal-oralvirus32001557http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1002512
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Rabies (treated)1%1.6bites0-deaths due to vaccine complicationsvirusunknown35,000115,0001.22http://books.google.co.uk/books?id=TRyXTLXNA2YC&pg=PA662&lpg=PA662&dq=rabies+%22fatality+rate%22+vaccinated&source=bl&ots=sZQ1wRKW68&sig=Cd7arUDNIjuxRgSWLpLfaJHupPI&hl=en&sa=X&ei=zks-VPOGBoKS7AaQ0YCAAw&redir_esc=y#v=onepage&q=rabies%20%22fatality%20rate%22%20vaccinated&f=false
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Rabies (untreated)100%1.6bites0-virusunknown35,000115,0001.22http://en.wikipedia.org/wiki/List_of_human_disease_case_fatality_rateshttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/rab-eng.phphttp://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1000053https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=20&ved=0CK0BEBYwEw&url=http%3A%2F%2Fwww.phac-aspc.gc.ca%2Flab-bio%2Fres%2Fpsds-ftss%2Frab-eng.php&ei=KSJEVI_mCqPg7QaIooDgBg&usg=AFQjCNGZx7rlokxJlDVWP2WN6zhrTBqjfw&sig2=k7X40YGQV2VTtm7e94Pq7w
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Rhinovirus0%6airborne droplet0.11nasal mucous, estimated R0virus0.41000---3http://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/rhinovirus-eng.phphttp://books.google.co.uk/books?id=5uMf4qCmghEC&pg=PA201&lpg=PA201&dq=rhinovirus+%22basic+reproductive+number%22+OR+%22basic+reproductive+rate%22&source=bl&ots=M5hiyWlzzL&sig=NG0Ydv1t-UJ3o1GGGeyLMkP5KHE&hl=en&sa=X&ei=hpo3VLWrJebB7Aa9xIHIBw&redir_esc=y#v=onepage&q=rhinovirus%20%22basic%20reproductive%20number%22%20OR%20%22basic%20reproductive%20rate%22&f=falsehttp://pathmicro.med.sc.edu/virol/rhino.htmhttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/rhinovirus-eng.php
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Rotavirus0%17.6fecal-oral760
mostly causes death in children & infants
virus<100450,000-230,000http://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/rotavirus-eng.phphttp://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0042320#pone-0042320-t003http://wwwnc.cdc.gov/eid/article/20/1/13-0019_articlehttp://www.cdc.gov/vaccines/pubs/surv-manual/chpt13-rotavirus.html
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Rubella0%6airborne dropletvirus10-60-1-57http://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/rub-eng.php
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Salmonella1%0.8food0.690wet swine faeces, one strain can survive for 6 years on rubber & concrete!bacterium100115,000284,100http://jid.oxfordjournals.org/content/198/1/109.longhttp://www.nhs.uk/chq/Pages/how-long-do-bacteria-and-viruses-live-outside-the-body.aspxhttp://www.sciencedirect.com/science/article/pii/S002555641300148Xhttp://www.cdc.gov/biosafety/publications/bmbl5/BMBL5_sect_VIII_a.pdf
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SARS9.60%2.4airborne droplet17respiratory secretionsvirus20 - can't substantiate0001.23.6http://en.wikipedia.org/wiki/Severe_acute_respiratory_syndromehttp://wwwnc.cdc.gov/eid/article/11/8/pdfs/04-0449.pdfhttp://en.wikipedia.org/wiki/Basic_reproduction_number
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Scarlet Fever0.50%2.8body fluidsbacteriumunknown-3-57http://www.emedicinehealth.com/scarlet_fever/page10_em.htmhttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/strep-pyogenes-eng.php
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Seasonal Flu0.10%2.5airborne droplet12virus790375,00026,000-23http://en.wikipedia.org/wiki/List_of_human_disease_case_fatality_rateshttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/influenza-grippe-b-c-eng.phphttp://en.wikipedia.org/wiki/Basic_reproduction_numberhttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/influenza-a-eng.php
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Smallpox15%6airborne dropletvirus100057http://www.absa.org/abj/abj/040903nicas.pdf
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Swine Flu (H1N1)0.20%1.5airborne droplet0.42virus500
360,000 (during 2009 pandemic)
12,500 (during 2009 pandemic
-1.41.6http://www.cidrap.umn.edu/news-perspective/2013/01/study-puts-global-2009-pandemic-h1n1-infection-rate-24http://www.panama-guide.com/article.php/20090517152331424https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=6&ved=0CE4QFjAF&url=http%3A%2F%2Fwww.mdpi.com%2F1999-4915%2F2%2F8%2F1530%2Fpdf&ei=PvBEVKO5Hcau7Abyy4GADw&usg=AFQjCNGSB-f7wflPOcjC933IbtZwfvUtPA&sig2=rCX6dQtdVhSGXsBFXF-VIQ
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Syphilis (untreated)33%0.9sexual contact11-our calcsbacterium5779,0002846,000http://en.wikipedia.org/wiki/Syphilishttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2476079/?page=1http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360276/
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Tuberculosis (untreated)
60%10airborne droplet60120wood, faecesbacterium<10930,000570220,0001.41010http://en.wikipedia.org/wiki/Tuberculosishttp://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/tuber-eng.phphttps://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=13&ved=0CHkQFjAM&url=http%3A%2F%2Fwww.phac-aspc.gc.ca%2Flab-bio%2Fres%2Fpsds-ftss%2Ftuber-eng.php&ei=KSJEVI_mCqPg7QaIooDgBg&usg=AFQjCNFifPMWHqE30pqhPTge6aPlMeTVug&sig2=om5rubwGRsmTwETKmR05oA
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Typhoid20%2.8fecal-oralfatality: 1-4% if treated bacterium100,000200,0000-http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0002642http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484760/http://www.mayoclinic.org/diseases-conditions/typhoid-fever/basics/causes/con-20028553
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484760/
http://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/salmonella-ent-eng.php
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bugs
bugs for vz
outrageous facts
physicians per 1,000
amends