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ADAPTIVE/IQ
ADAPTIVE/IQ (https://adaptive-iq.com/)
Dr. Molly created custom supplement packs based on this formula at ADAPTIVE/IQ that ready for shipping.
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Now you don't have to order off amazon.com as there are significant shipping delays.
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These packs contain everything you need to optimize your healthspan and immunity.
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SUPPLEMENTTYPE
WHERE TO BUY
DOSE/DAY (DIVIDED)
MECHANISMCITATIONS
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Option 1: Quercetin 500mg (DON'T TAKE IF ON BLOOD THINNERS)
Nutraceutical
https://amzn.to/33QNyZU
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Coronavirus, which can cause respiratory syndrome, to date has affected over seventeen thousand individuals, especially in China. Coronavirus is interspecies and can also be transmitted from man to man, with an incubation ranging from 1 to 14 days. Human coronavirus infections can induce not only mild to severe respiratory diseases, but also inflammation, high fever, cough, acute respiratory tract infection and dysfunction of internal organs that may lead to death. Coronavirus infection (regardless of the various types of corona virus) is primarily attacked by immune cells including mast cells (MCs), which are located in the submucosa of the respiratory tract and in the nasal cavity and represent a barrier of protection against microorganisms. The virus activates MCs which release early inflammatory chemical compounds including histamine and protease; while late activation provokes the generation of pro-inflammatory IL-1 family members including IL-1 and IL-33. Here, we propose for the first time that inflammation by coronavirus may be inhibited by anti-inflammatory cytokines belonging to the IL-1 family members.; He says it's possible that they will have results on quercetin's ability to treat COVID-19 within 60 days of a clinical trial starting... "It is not expensive. It's a natural product. It's found in nature and purified from plants. Compared to what is available now, and that is being tried in China right now, it doesn't compare in terms of price," Mbikay said. Quercetin also acts as a senolytic. HEALTHSPAN: Quercetin is a flavonol found in minute quantities in foods like broccoli, apples, berries, grapes, tea, and wine. It stimulates immunity, and acts as a zinc ionophore meaning it helps zinc pass the cell wall where it can help inhibit viral replication. It helps protect the body against inflammation and helps reduce the release of histamine in allergic conditions. It helps boost immunity during periods of intensive physical training or high stress. We have formulated it alongside omega 3 fish oils and green tea extract because research shows this combination helps reduce muscle damage and inflammation after intense exercise. Quercetin lowers the production of inflammatory chemicals (cytokines such as interleukin IL-4) and inhibits enzymes (eg lipoxygenase) involved in triggering inflammation.2
https://www.preprints.org/manuscript/202003.0226/v1; https://examine.com/topics/coronavirus/#summary3-0; Smith, Micholas; Smith, Jeremy C. (2020): Repurposing Therapeutics for COVID-19: Supercomputer-Based Docking to the SARS-CoV-2 Viral Spike Protein and Viral Spike Protein-Human ACE2 Interface. ChemRxiv. Preprint. https://doi.org/10.26434/chemrxiv.11871402.v3 https://s3-eu-west-1.amazonaws.com/itempdf74155353254prod/11871402/Repurposing_Therapeutics_for_COVID-19__Supercomputer-Based_Docking_to_the_SARS-CoV-2_Viral_Spike_Protein_and_Viral_Spike_v4.pdf; https://pubs.acs.org/doi/10.1021/jf5014633; https://www.rightnowmn.org/combating_covid_19_with_zinc_and_quercetin; https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109180; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812309/
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Option 2: Quercetin with Nettle (choose this if you have allergies)
Herbs
https://amzn.to/
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https://www.biolifesas.org/biolife/2020/02/04/mast-cells-contribute-to-coronavirus-induced-inflammation-new-anti-inflammatory-strategy/; https://www.cbc.ca/radio/thecurrent/the-current-for-feb-28-2020-1.5479561/as-coronavirus-spread-speeds-up-montreal-researchers-will-trial-an-anti-viral-treatment-for-covid-19-in-china-1.5480134; https://www.evms.edu/media/evms_public/departments/internal_medicine/Marik-Covid-Protocol-Summary.pdf; NEUROPLASTICITY https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745323/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005410/ STRESS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600673/; Mlcek J, et al. Quercetin and Its Anti-Allergic Immune Response. Molecules. 2016;21(5):623.; https://www.ncbi.nlm.nih.gov/pubmed/28326454
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Turmeric Standardized Extract 500 mg
Herbs
https://amzn.to/3dw1P2N
2Curcumin, a key component of turmeric, has anti-inflammatory actions and antiviral effects against a variety of similar viruses.: Also protects the liver from pro-inflammatory lifestyles during quarantines https://europepmc.org/article/pmc/pmc4637698
https://www.preprints.org/manuscript/202003.0226/v1; https://pubmed.ncbi.nlm.nih.gov/17663539/; https://pubmed.ncbi.nlm.nih.gov/16216010/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278270/ NEUROPLASTICITY: https://pubmed.ncbi.nlm.nih.gov/29667473/; https://pubmed.ncbi.nlm.nih.gov/30268781/;
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Option 1: Green Tea Standardized Extract 300mg
Herbs
https://amzn.to/2JoLPBP
2 - 3EGCG (epigallocatechin-3-gallate) is a specific flavanol derivative, flavan-3-ol. Green tea contains the most EGCG. Molecular docking shows EGCG can interact well with DNMTs, ACE-2, and helicase.[9].
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882434/; https://www.preprints.org/manuscript/202003.0226/v1; COVID https://examine.com/topics/coronavirus/#summary3-0; https://pubmed.ncbi.nlm.nih.gov/30675873/; https://pubmed.ncbi.nlm.nih.gov/30675873/ https://www.rightnowmn.org/combating_covid_19_with_zinc_and_quercetin NEUROPLASTICITY https://www.ncbi.nlm.nih.gov/pubmed/31746040; https://www.ncbi.nlm.nih.gov/pubmed/26917271; https://www.ncbi.nlm.nih.gov/pubmed/31349535; https://pubs.acs.org/doi/10.1021/jf5014633
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Option 2: Green Tea Brewed 3 cups a day
Herbs
https://breakawaymatcha.com/
1 cups a day
I personally recommend matcha because it's way more delicious than regular green tea plus you can drink less of it for the same amount of EECG as regular green tea. "Matcha contains about three times more antioxidants than high-quality regular green tea. As such, 2 cups (474 ml) of matcha may provide equal amounts of plant compounds as 6 cups "
https://www.healthline.com/nutrition/matcha-green-tea
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Vitamin D-3 (Cholecalciferol) 2000 IU (preferably with K1 & K2)
Vitamins
https://amzn.to/2UqAOpL
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Vitamin D can help prevent upper respiratory infections.[46][47][48][49] People’s spending a lot of time indoors in the winter is tied to seasonal flu through higher viral transmission in closed areas and a lack of sun (in addition to allowing your skin to synthesize vitamin D, solar UV rays can inactivate viruses).[50][51] But the impact of supplemental vitamin D on the novel coronavirus is unknown. Do not take high amounts just because you’ve heard that “vitamin D is good for the immune system”!
https://examine.com/topics/coronavirus/#summary3-0; https://www.healthline.com/nutrition/immune-boosting-supplements#1.-Vitamin-D; https://pubmed.ncbi.nlm.nih.gov/30675873/; Vitamin D₃ Metabolites Enhance the NLRP3-dependent Secretion of IL-1β From Human THP-1 Monocytic Cells. J Cell Biochem. 2015;116(5):711. https://www.ncbi.nlm.nih.gov/pubmed/25639477; https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23762029/; https://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.24985; https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/31866999/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842685/; https://thorax.bmj.com/content/70/7/617
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Option 1: Vitamin C Liposomal 1000 mg
Vitamins
https://amzn.to/2JmQ4xD
1 packet When sepsis happens, the cytokine surge caused by sepsis is activated, and neutrophils in the lungs accumulate in the lungs, destroying alveolar capillaries. Early clinical studies have shown that vitamin C can effectively prevent this process. In addition, vitamin C can help to eliminate alveolar fluid by preventing the activation and accumulation of neutrophils, and reducing alveolar epithelial water channel damage. At the same time, vitamin C can prevent the formation of neutrophil extracellular traps, which is a biological event of vascular injury caused by neutrophil activation.
https://clinicaltrials.gov/ct2/show/NCT04264533; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180524/; https://pubmed.ncbi.nlm.nih.gov/28224112/; https://www.ncbi.nlm.nih.gov/pubmed/28326454
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Option 2: Vitamin C 1000 mg
Vitamins
https://amzn.to/2X1IJvJ
2Dr. Anthony Fauci, director of NIAID, NIH openly recognizes the importance of Vit C in the fight against virus. Vitamin C has antioxidant activity and may reduce oxidative stress and inflammation (57,62), https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105280/
https://youtu.be/xkyO1DTqoWQ
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Zinc 30mgMinerals
https://amzn.to/2wC2i2S
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Coronaviruses appear to be susceptible to the viral inhibitory actions of zinc. Zinc may prevent coronavirus entry into cells and appears to reduce coronavirus virulence. ; Insurance of good zinc status, particularly in the very young and the elderly, would likewise seem to be prudent, as zinc supports the effective function and proliferation of various immune cells.23,35 This effect might be pertinent to the significant 27% reduction in total mortality observed in elderly subjects who received high-dose zinc in the AREDS1 multicenter trial.36 Numerous studies reveal that zinc supplements may protect against respiratory tract infections like the common cold (12Trusted Source, 13Trusted Source).
https://pubmed.ncbi.nlm.nih.gov/19710611/; https://pubmed.ncbi.nlm.nih.gov/19710611/; https://www.sciencedirect.com/science/article/pii/S0033062020300372?via%3Dihub
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NAC 600 mg (N-Acetyl Cysteine)
Antioxidants
https://amzn.to/2UGTqRy
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The authors draw attention to several randomized clinical studies in humans that have found that over the counter supplements such as n-acetylcysteine (NAC), which is used to treat acetaminophen poisoning and is also used as a mucus thinner to help reduce bronchitis exacerbations, and elderberry extracts, have evidence for shortening the duration of influenza by about two to four days and reducing the severity of the infection. The authors also note several nutraceuticals such as spirulina, beta-glucan, glucosamine, and NAC have either been found to reduce the severity of infection or to cut the rate of death in half in animals infected with influenza. Furthermore, one clinical study in humans testing spirulina noted significant reductions in viral load in those infected with HIV.; Mucolytic; symptomatic relief; oral N-acetylcysteine ameliorated the intestinal effects of porcine epidemic diarrhea coronavirus in piglets
https://www.sciencedirect.com/science/article/pii/S0033062020300372?via%3Dihub; https://pubmed.ncbi.nlm.nih.gov/19710611/; https://www.elsevier.com/about/press-releases/research-and-journals/recent-research-points-the-way-toward-a-practical-nutraceutical-strategy-for-coping-with-rna-virus-infections-including-influenza-and-coronavirus https://www.cebm.net/covid-19/registered-trials-and-analysis/ https://www.biospace.com/article/releases/new-covid-19-hope-clinical-trial-recommendations-introduced-today-may-reduce-or-eliminate-mechanical-ventilation-for-coronavirus-patients/ https://www.ncbi.nlm.nih.gov/pubmed/32087337 https://www.sciencedirect.com/science/article/pii/S0033062020300372?via%3Dihub
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Option 1: Organic Mushroom Complex 1.9 g
Mushroom
https://amzn.to/2Uoy2Bq
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With respect to practical efforts to prevent and control RNA virus infections, nutraceutical preparations intended to provide protection in this respect might reasonably also include... beta-glucan — which can amplify dendritic cell activation via dectin-1 and CR3 receptors; this agent has clinically documented immunostimulant effects, and has been shown to protect mice challenged with influenza virus.33,34 (Polysaccharide cell wall preparations from certain mushrooms and sea weeds have comparable activity).;
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684115/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788765/; https://pubmed.ncbi.nlm.nih.gov/28595034/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618583/;
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Option 2: Malama Mushrooms 1 scoop
Mushroooms
https://www.malamamushrooms.com/
1 - 2 servings The authors also note several nutraceuticals such as spirulina, beta-glucan, glucosamine, and NAC have either been found to reduce the severity of infection or to cut the rate of death in half in animals infected with influenza.
https://www.sciencedirect.com/science/article/pii/S0033062020300372; https://www.elsevier.com/about/press-releases/research-and-journals/recent-research-points-the-way-toward-a-practical-nutraceutical-strategy-for-coping-with-rna-virus-infections-including-influenza-and-coronavirus;
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Selenium 100 mcgMinerals
https://amzn.to/39p9kFu
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Since selenium is an essential cofactor for certain peroxidases, and selenium deficiency has been endemic in certain regions of China and other parts of the world, insuring adequacy of selenium nutrition might also be appropriate in this context.21 Not surprisingly, influenza is more pathogenic in selenium-deficient mice, and selenium deficiency also increases the rate at which viruses can mutate, promoting the evolution of strains that are more pathogenic and capable of evading immune surveillance.22
https://www.sciencedirect.com/science/article/pii/S0033062020300372; https://www.mdpi.com/2072-6643/11/9/2101/htm; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288282/; https://pubmed.ncbi.nlm.nih.gov/30593352/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165773
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Chlorophyll (contains copper and balances the zinc supplementation)
Specialty
https://amzn.to/2UJUzYj
1 dropperZinc supplementation is known to cause copper deficiency.
https://www.deannaminich.com/copper-to-zinc-achieving-the-right-balance/
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Magnesium glycinate 120 mg
Minerals
https://amzn.to/2URhCkc
1 - 4x daily
Along with being a potential contributing factor for anxiety and depression, magnesium deficiency can also have a lot of other effects on the body, including increasing the risk of heart disease, migraines, and high blood pressure... magnesium also controls the hypothalamic-pituitary-adrenocortical (HPA) axis, which is the hub of the body’s stress response system. Studies have found that feelings of fear and panic can be significantly reduced with greater magnesium intake
https://www.ncbi.nlm.nih.gov/pubmed/28445426 ; https://www.ncbi.nlm.nih.gov/pubmed/26166051; https://www.ncbi.nlm.nih.gov/pubmed/30562392
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Omega 3's (EPA DHA) 2 - 4 g
Specialty
https://www.npure-3.com/shop?funk=inst_val_sprak&Sprak_Suffix=EN&Valuta_ID=USD&funk2=startsida
1 - 2 x daily
I use this for brain protection during times of high stress. "The exposure to n-3 fatty acids enhances adult hippocampal neurogenesis associated with cognitive and behavioral processes, promotes synaptic plasticity by increasing long-term potentiation and modulates synaptic protein expression to stimulate the dendritic arborization and new spines formation. On this basis we review the effect of n-3 fatty acids on adult hippocampal neurogenesis and neuroplasticity."
https://onlinelibrary.wiley.com/doi/full/10.1002/jpen.1672;%20; https://onlinelibrary.wiley.com/doi/abs/10.1111/jhn.12493; https://www.ncbi.nlm.nih.gov/pubmed/23746276; https://www.sciencedirect.com/science/article/abs/pii/S0166223613001987; https://www.ncbi.nlm.nih.gov/pubmed/31480215; https://diabetes.diabetesjournals.org/content/diabetes/65/3/673.full.pdf#neuroscience
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Resveratrol 1000 mgSpecialty
https://amzn.to/3bKHPre
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Middle East Respiratory Syndrome coronavirus (MERS-CoV) is an emerging viral pathogen that causes severe morbidity and mortality. Up to date, there is no approved or licensed vaccine or antiviral medicines can be used to treat MERS-CoV-infected patients. Here, we analyzed the antiviral activities of resveratrol, a natural compound found in grape seeds and skin and in red wine, against MERS-CoV infection... Resveratrol significantly inhibited MERS-CoV infection and prolonged cellular survival after virus infection. We also found that the expression of nucleocapsid (N) protein essential for MERS-CoV replication was decreased after resveratrol treatment. Furthermore, resveratrol down-regulated the apoptosis induced by MERS-CoV in vitro. By consecutive administration of resveratrol, we were able to reduce the concentration of resveratrol while achieving inhibitory effectiveness against MERS-CoV.
https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-017-2253-8; NEUROPLASTICITY https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690610/
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B Complex (track intakes with Cronometer & replace if deficient)
Vitamins
https://amzn.to/2VaaJdU
1B vitamins, including B12 and B6, are important for healthy immune response. Yet, many adults are deficient in them, which may negatively affect immune health
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358464/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358464/;
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MEDICAL
This fomula does not constitute medical advice. Dr. Molly Maloof does not claim these supplements prevent, treat, or cure Covid-19 infections. Much of the science on Covid-19 is very new and very early.
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DISCLAIMER
Dr. Molly providing this information does not mean she is making recommendations. These recommendations are for research purposes only. Please consult with your physician, naturopath or other health care provider before embarking on any supplement regimen.
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"the US Food and Drug Administration (FDA) and Federal Trade Commission (FTC) are closely watching for misleading product claims around COVID-19 prevention or treatment and even a general "immunity"
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claim on a product could be considered an implied claim about COVID-19 given the current environment." https://www.nutraingredients.com/Article/2020/03/24/Coronavirus-immunity-claim-warning-for-Omega-3-industry
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PROTEIN & PHYTONUTRIENT ELIXIR (for when the power goes out and you need nutrients or don't have access to fresh meat, fruits and veggies)
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Kion Aminos1 ScoopAmino Acid
https://amzn.to/2QRVWDc
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Peak Performance Unsweetened superfood powder
Phytonutrients
https://amzn.to/2Jkk2T7
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Option 1: Gundry Reds
Phytonutrients
https://amzn.to/3aq9ttC
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Option 2: Superfood Vital Reds
Phytonutrients
https://amzn.to/2UovWSa
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Montmorillinite Clay 1/8 teaspoon (for detoxification)
Mineral
https://amzn.to/3bzgEQ7
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Magnesium Ascorbate 1/4 teaspoon (relaxes muscles; adds vitamin c)
Mineral/Vitamin
https://amzn.to/2R9W2qb
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L Glutamine powder 1/2 teaspoon (primary fuel for immune cells)
Amino Acid
https://amzn.to/2wOEDfB
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NMN Powder 1/2 teaspoon (energy)
Nutraceutical
https://amzn.to/2wBKK71
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Instructions: Add all of these to a large water bottle. Great for exercise recovery as well!
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I AM SICK FORMULA
AMPMRESEARCH
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Vitamin D-3 2,000 IU / day (Cholecalciferol)
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https://amzn.to/2UqAOpL
Verway M, et al. Vitamin D Induces interleukin-1β Expression: Paracrine Macrophage Epithelial Signaling Controls M. Tuberculosis Infection. PLoS Pathog. 2013;9(6):e1003407. 37 Tulk SE, et al. Vitamin D₃ Metabolites Enhance the NLRP3-dependent Secretion of IL-1β From Human THP-1 Monocytic Cells. J Cell Biochem. 2015;116(5):711.; https://examine.com/topics/coronavirus/#summary3-0; https://www.healthline.com/nutrition/immune-boosting-supplements#1.-Vitamin-D; https://pubmed.ncbi.nlm.nih.gov/30675873/.
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Vitamin C 2,000 mg / day
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https://amzn.to/2X1IJvJ
https://youtu.be/xkyO1DTqoWQ; https://clinicaltrials.gov/ct2/show/NCT04264533
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Melatonin 3 mg / night
1
https://amzn.to/2xkzpse
Melatonin is potent inhibitor of the NLRP3 inflammasome! If the inflammasome is over-activated, a cytokine storm results. Melatonin adjuvant use in COVID-19: anti-inflammation, anti-oxidation, immune response regulation has been repeatedly demonstrated in respiratory disorder models induced by infections and associated complications. Melatonin has a high safety profile. https://www.sciencedirect.com/science/article/pii/S0024320520303313 Melatonin: Melatonin has been shown to inhibit NFkB activation and NLRP3 inflammasome activation.20 In fact, the age-related decline in melatonin production is one proposed mechanism to explain why children do not appear to have severe symptoms and older adults do. Melatonin also reduces oxidative lung injury and inflammatory cell recruitment during viral infections.21 Typical dosing of melatonin varies widely from 0.3mg to 20mg (the latter used in the oncological setting). file:///Users/mollymaloof/Downloads/Integrative%20Considerations%20during%20the%20COVID%203.18.20.pdf
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Garlic 500 mg / day1
https://amzn.to/2UQ4TiM
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465033/;%20https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417560/; 38 Arreola R, et al. Immunodulation and Anti-Inflammatory Effects of Garlic Compounds. J Immunol Res. 2015;2015:401630.
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Citicholine 1000 mg / day
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https://amzn.to/2yCIrRz
The inhibition of cPLA2α activity, which produces lysophospholipids (LPLs) by cleaving at the sn-2 position of phospholipids, had profound effects on viral RNA and protein accumulation in human coronavirus 229E-infected Huh-7 cells.; https://jvi.asm.org/content/92/4/e01463-17; https://www.ncbi.nlm.nih.gov/pubmed/19401146
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Zinc 50 - 75 mg / day
1
https://amzn.to/3ccfc6T
https://www.evms.edu/media/evms_public/departments/internal_medicine/Marik-Covid-Protocol-Summary.pdf; https://pubs.acs.org/doi/10.1021/jf5014633
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Quercetin 500 mg BID (twice a day) DON'T TAKE IF ON BLOOD THINNERS
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https://amzn.to/33QNyZU
https://www.evms.edu/media/evms_public/departments/internal_medicine/Marik-Covid-Protocol-Summary.pdf; https://pubs.acs.org/doi/10.1021/jf5014633
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NAC 600 mg BID (twice a day)
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https://amzn.to/2UGTqRy
https://www.sciencedirect.com/science/article/pii/S0033062020300372?via%3Dihub; https://pubmed.ncbi.nlm.nih.gov/19710611/; https://www.elsevier.com/about/press-releases/research-and-journals/recent-research-points-the-way-toward-a-practical-nutraceutical-strategy-for-coping-with-rna-virus-infections-including-influenza-and-coronavirus https://www.cebm.net/covid-19/registered-trials-and-analysis/ https://www.biospace.com/article/releases/new-covid-19-hope-clinical-trial-recommendations-introduced-today-may-reduce-or-eliminate-mechanical-ventilation-for-coronavirus-patients/ https://www.ncbi.nlm.nih.gov/pubmed/32087337 https://www.sciencedirect.com/science/article/pii/S0033062020300372?via%3Dihub
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COVID 19 &
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361828/
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SARS
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619128/
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