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2025-26 Week by Week Plan. Flipped learning using Learn-Biology.com
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Questions? Email mr.w@learn-biology.com
Sign up for a free-trial account
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Designed for use with our interactive College-Board Approved AP Biology Curriculum
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Notes about sequencing
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Week #Week BeginsVacations/ notes /milestonesTopics to teachHomework: Interactive tutorials on Learn-Biology.comLabs/activitiesSelected Practice FRQsFRQ Scoring Guide
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1Mon, 8/11/25
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W: 8/13: First day of schoolCourse overview
Key Themes of Biology		AP Bio Course Introduction (themes and concepts)
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Introducing Natural selectionMaking of the Fittest video and HHMI lab (rock pocket mouse)
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Peppered Moth Evolution Simulation (optional)
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2Mon, 8/18/25If needed, have students work through Basic ChemistryM/T: Finish Course Intro/ Natural selection (quiz or test)
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W: 1.1: Properties of WaterTopic 1.1: The Chemistry of Water and Hydrogen BondingProperties of water lab (qualitative)
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Plant brocolli seeds for whole plant transpiration (in November)Introduction to standard deviation/standard errorProperties of water lab (with stats)
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Antibiotic case study from National center for Case Study Teaching...Properties of water
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quiz: properties of water and standard deviation
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3Mon, 8/25/251.2 - 1.6: Biochemistry Introduction (carbon, functional groups, carbohydrates, lipids)Topic 1.2: Carbon and Functional Groups
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Topic 1.3: Monomers and Polymers
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Topics 1.4 - 1.6 Overview: The Four Biomolecule Familiesmolecular model building lab
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4Mon, 9/1/259/2: Labor Day
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Topic 1.4: Carbohydrates
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Topic 1.5: Lipids
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Starch Amylase Lab/Demo
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Topic 1.7: Proteins POGIL: Biochemistry Basics
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Carbon and Two Molecules
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5Mon, 9/8/251.2 - 1.6: Biochemistry (carbs, lipids, proteins, intro to nucleic acids) (finish)Topic 1.6: Nucleic Acids OverviewPOGIL: Protein StructureProtein Structure (includes SG)
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Unit 1 Cumulative Flashcards and QuizzesMacromolecule Party
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W/Th: Finish Biochemistry/Unit 1 (review);
F: Test on Unit 1
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6Mon, 9/15/25Go over U1 Test; Start CellsTopic 2.2: Surface Area and Volume
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W: 2.1: Cell size Lab (agar cubes)Topic 2.1, Parts 1-3: Cell Structure and FunctionCell Size lab
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2.1 - 2.2: Cell Parts, S & F
viewing cells lab
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7Mon, 9/22/252.10 - 2.11: Compartmentalization (endomembrane system), Origins of EukaryotesTopic 2.9: Cell Compartmentatilization and the Endomembrane SystemIf time: cell size lab, part 2 (students design their own experiment)
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Topic 2.10: Origins of Cellular CompartmentalizationOrganelles in Different Cell TypesOrganelles in different cell types with scoring guides
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8Mon, 9/29/25
2.4 - 2.9: Membrane structure, Transport, Osmosis		Topic 2.3: Cell Membrane StructureMembrane Structure, Membrane Function POGILSCell Evolution/PlasmodiumCell Evolution/Plasmodium SG
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Topics 2.4-2.6, 2.8: Membrane TransportGummy Bear Osmosis lab
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Topic 2.7: Osmosis and Water PotentialDiffusion and osmosis labsOsmosis (lab assistant)Osmosis (lab assistant) SG
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Unit 2 Cumulative Flashcards and Quizzes
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Unit 2 Progress Checks on CB websiteProtein Secretion Protein Secretion SG
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Test on Unit 2 (Cells and Membranes)
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9Mon, 10/6/25BUSD Staff development Day
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3.1-3.3: EnzymesTopics 3.1 to 3.2: EnzymesLiver Enzymes Lab (or Demo)
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Potato Catalase enzyme labEnzymes (1988: SG on 2nd page)
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POGIL: Enzymes and cell regulationEnzyme Lab (2015); SG on 2nd page
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3.4, 3.6: Cellular Energy and RespirationTopics 3.3, 3.5, Part 1: Cellular Energy and Cell Respiration
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10Mon, 10/13/25Topics 3.3, 3.5, Part 2: Glycolysis
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Topics 3.3, 3.5 Part 3: The Link Reaction and the Krebs CycleRespiration with respirometersColumn GColumn H
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Topics 3.3, 3.5, Part 4: The Electron Transport Chain and ChemiosmosisPeter Mitchell (SG on 2nd page)
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Respiration in SealsRespiration in Seals SG
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11Mon, 10/20/25Anaerobic RespirationTopics 3.3, 3.5, Part 5: Anaerobic Respiration and FermentationFermentation demonstrations (yeast and yogurt)Respiration in Yeast (SG on 2nd page)
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Cellular Respiration Diagrams for Mastery
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Cellular Respiration ConsolidationEnzymes, Cell Respiration Review SheetPOGILs on cell respiration
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Cellular Respiration Quiz
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3.5: PhotosynthesisTopic 3.4, Part 1, Introduction to Photosynthesis
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11Mon, 10/27/25Topic 3.4, Part 2: Chloroplasts and the Two Phases of Photosynthesisphotosynthesis with spinach disks
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Finish Photosynthesis (calvin cycle)Topic 3.4, Part 3, Light, Pigments and PhotosynthesisPhotosyntheis POGILS
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Topic 3.4, Part 4: Photosynthesis, the Light ReactionsPhotosynthesis Diagrams for MasteryThree Photosynthesis FRQs (Seedling growth, DPIP, absorption spectra)Three Photosynthesis FRQ Scoring Guides
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Fri, 11/1/24BUSD Secondary Break
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12Mon, 11/3/25Topic 3.4, Part 5, The Calvin Cycle
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PSN review and quizUnit 3 Review: cumulative Flashcards and quizzes
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Photosynthesis Review Sheet
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If plants are ready, transpiration labTranspiration Tutorialtranspiration lab
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Unit 3 Test
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4.6: Cell cycle, MitosisTopic 4.5: Mitosis and the Cell CycleViewing Mitosis lab
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13Mon, 11/10/2511/11: veteran's dayStart 4.1 - 4.4: Cell Communication/ Signal Transduction Topic 4.1: Introduction to Cell CommunicationPOGILS: Cell Communication, signal transduction
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Topics 4.2 – 4.3, Part 1: Introduction to Signal TransductionCell Communication (with scoring guide and response)
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Topics 4.2 – 4.3, Part 2: Reception
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Topics 4.2 – 4.3, Part 3: Signal Transduction
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Topics 4.2 – 4.3 Part 4: Signaling Hormones and Gene RegulationGymnema Tea Lab
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Mon, 11/17/254.7, part 1: Cell cycle Regulation (cyclins, kinases, etc) Topic 4.6: Cell Cycle Regulation Cell Cycle Regulation POGIL
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Topic 4.7, part 2: Cancer and ApoptosisTopic 4.6, part 2: Cancer and ApoptosisHHMI Biointeractive: The Eukaryotic Cell Cycle and CancerCell Division, EGF, and CancerCell Division, EGF, Cancer SG
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4.5: feedback/homeostasis (blood sugar, thermoregulation, osmoregulation)Topic 4.5, Part 1: Homeostasis and Regulation (with thermoregulation as an illustrative example)
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4.5, Part 2: Feedback Loops4.5, Part 2: Feedback LoopsFeedback Mechanisms POGILThermoregulation (SG on p2)
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4.5, Part 3: Blood Glucose regulation4.5, Part 3, Blood Glucose RegulationBlood sugar regulation, Feedback POGIL
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14Mon, 11/24/25THANKSGIVING
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15Mon, 12/1/254.5, Part 4, Understanding Diabetes4.5, Part 4, Understanding DiabetesBlood glucose metabolism (with SG)
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Test/quiz: Feedback/Homeostasis
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Unit 4 ReviewUnit 4 Flashcards, QuizzesAlcohol and Urine Production (with SG)
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Unit 4 TEST
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16Mon, 12/8/25IMPORTANT: we recommend teaching unit 6 before unit 5
6.1-6.2: DNA structure, replication		Topics 6.1 and 6.2, Part 1: DNA Structure (Review and Extension)Discovery of DNA inductive learning activity
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Topics 6.1 and 6.2, Part 2: DNA ReplicationPulse chase primer/Meselson-Stahl experiment (HHMI)Hershey Chase Experiment, with SCORING GUIDE
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6.3 - 6.4: Transcription/Translation		Topic 6.3. Transcription
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Topic 6.4, Part 1: The Genetic CodePOGILS: transcription, translationDNA Replication (Meselson-Stahl and Okazakis), with scoring guides
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Topic 6.4, Part 2: Translation/Protein Synthesis
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17Mon, 12/15/25(this is finals week at BHS, special scheduleFinish Transcription/TranslationTopic 6.4, Part 3 (optional extension): Protein Targeting to the Rough E.R.Transcription and Translation Worksheet
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Note: I typically skipped giving a semester final and used the time for teaching more contentStart Topic 6.7, Viruses, MutationTopic 6.7, Part 1: Virus Structure and Viral Life Cycles (Lytic, Lysogenic, and Retroviral)Read this note about why I teach viruses (and why you should, too)
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Mon, 12/22/25WINTER RECESSRecommended time save: assign Origin of LIfe over spring break
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Mon, 12/29/25WINTER RECESS