| A | B | C | D | E | F | G | H | |
|---|---|---|---|---|---|---|---|---|
1 | Best guess | 25th percentile | 75th percentile | 25th percentile cost- effectiveness | 75th percentile cost- effectiveness | |||
2 | Grant size | $ 5,200,000 | ||||||
3 | Disability benefits | |||||||
4 | Number of infants with clubfoot treated by MiracleFeet | 9,800 | 8,000 | 11,000 | 7 | 10 | ||
5 | Percentage of those infants who would have been treated without MiracleFeet | 9% | 16% | 2% | 8 | 9 | ||
6 | Probability of condition | 100% | ||||||
7 | Long-term effectiveness of Ponseti treatment | 50% | 25% | 75% | 4 | 12 | ||
8 | Cost per case of clubfoot averted | $1,200 | ||||||
9 | Expected years of clubfoot disability averted per successful treatment | 62 | ||||||
10 | Moral weight for each year of clubfoot averted | 0.5 | ||||||
11 | Moral weight for each lifetime of clubfoot averted | 30 | 15 | 40 | 4 | 11 | ||
12 | Cost-effectiveness from disability benefits only | 7 | ||||||
13 | Primary benefit streams (as % of total) | |||||||
14 | Disability benefits | 80% | ||||||
15 | Increased income in adulthood | 20% | ||||||
16 | Additional upside and downside adjustments | 0.90 | ||||||
17 | Supplemental charity-level adjustments | 94% | ||||||
18 | Supplemental intervention-level adjustments | 106% | ||||||
19 | Downstream costs to government inccurred as a result of funding to NGO (leveraging) | 96% | ||||||
20 | Chance that other funders fund similar programs without us (funging) | 94% | ||||||
21 | Additional benefits and downside adjustments | 1.1 | 0.9 | 1.3 | 7 | 10 | ||
22 | Final cost-effectiveness (after all adjustments) | 8 | ||||||
23 | Cost per infant treated | $530 | ||||||
24 | ||||||||
25 |