Organic Chemistry.xlsx

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3			Chemistry: Organic Chemistry (6 Units)
4			Subject (Paper Code) : 88637
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6	Sr No	Question	Answer1	Answer2	Answer3	Answer4	Correct Option	Topic
7	1	Two stereochemically identical faces of a molecule are called __________ faces.	homotopic	heterotopic	atopic	non-topic	Answer1	Unit1
8	2	A reaction which predominantly gives only one diastereomer of all possible diastereomers of the product is called _______ reaction.	enantioselective	diastereoselective	enantiospecific	diastereospecific	Answer2	Unit1
9	3	If a particular enantiomer of reactant gives a specific enantiomer of the product then it is ________.	enantioselectivity	diastereoselectivity	enantiospecificity	diastereospecificity	Answer3	Unit1
10	4	Treatment of an alcohol with thionyl chloride is an example of Substitution Nucleophilic _____ reaction.	Unimolecular	Bimolecular	internal	Unimolecular and Bimolecular	Answer3	Unit1
11	5	Addition of bromine to 2-butene is ______ reaction.	only stereoselective	only stereospecific	stereoselective as well as stereospecific	neither stereoselective nor stereospecific	Answer3	Unit1
12	6	Oxirane is a __ membered heterocyclic ring compound containing an oxygen atom.	3	4	5	6	Answer1	Unit1
13	7	All stereospcific reactions are ________.	always stereoselective	never stereoselective	rarely stereoselective	non- stereoselective	Answer1	Unit1
14	8	Formation of one enantiomer in majority is expressed as ______.	de	ee	ae	be	Answer2	Unit1
15	9	Oxirane on acid hydrolysis give _____.	aldehyde	ketone	germinal diol	vicinal diol	Answer4	Unit1
16	10	The reaction of an alkene with organic peroxy acid gives _______.	peroxide	aldehyde	ketone	epoxide	Answer4	Unit1
17	11	Bromination of alkene follows a ____ addition mechanism.	cis	trans	neither cis nor trans	cis as well as trans	Answer2	Unit1
18	12	Hydroxylation of alkene using potassium permangnate is ______ addition reaction.	syn	anti	syn as well as anti	neither syn nor anti	Answer1	Unit1
19	13	Osmium tetraoxide oxidation of alkene takes place through formation of _____ .	free radical	cyclic permangnate ester	cyclic osmate ester	carbanion	Answer3	Unit1
20	14	The ________ ligands are those atoms or groups which on replacement with another group give a pair of diastereomers.	enantiotopic	homotopic	diastereotopic	mesotopic	Answer3	Unit1
21	15	Dehydrohalogenation of an alkyl halide, forming an alkene is an eaxample of ______ reaction.	substitution	addition	rearrangement	elimination	Answer4	Unit1
22	16	_____ reactions go throgh formation of intimate ion pair.	SN1	SN1 and SN2	SNi	SN1 and SNi	Answer3	Unit1
23	17	Substitution Nucleophilic internal reactions result in ______ of configuration in product.	retention	inversion	racemisation	retention as well as inversion	Answer1	Unit1
24	18	Epoxidation of alkene is a _____ Addition.	syn	anti	syn and anti	neither syn nor anti	Answer1	Unit1
25	19	Reaction of an alkene with peroxy acid followed by hydrolysis gives ________.	aldehyde	ketone	germinal diol	vicinal diol	Answer4	Unit1
26	20	In ________ reactions, the stereochemistry of the product depends on the stereochemistry of the reactants.	stereoselective	stereospecific	enantioselective	diastereoselective	Answer2	Unit1
27	21	Treatment of an alcohol with thionyl chloride forms an ________.	aldehyde	alkyl chloride	acid	acid chloride	Answer2	Unit1
28	22	Treatment of an alcohol with thionyl chloride forms an intermediate ________.	chlorosulphide	chlorosulphate	chlorosulphite	sulphate	Answer3	Unit1
29	23	The two faces of acetone are ________ faces.	enantiotopic	diastereotopic	neither homotopic nor heterotopic	homotopic	Answer4	Unit1
30	24	Oxidation of 2-butene using osmium tetraoxide is ______ reaction.	only stereoselective	only stereospecific	stereoselective as well as stereospecific	neither stereoselective nor stereospecific	Answer3	Unit1
31	25	Reaction of 2-butene with peroxy acid is ________ reaction.	only stereoselective	only stereospecific	stereoselective as well as stereospecific	neither stereoselective nor stereospecific	Answer3	Unit1
32	26	The Substitution Nucleophilic internal reactions follow _______ order kinetics.	zero	first	second	third	Answer3	Unit1
33	27	Elimination bimolecular reactions require _____ geometry of the leaving groups.	synperiplanar	antiperiplanar	synclinal	anticlinal	Answer2	Unit1
34	28	Bromination of trans-2-butene gives ___-2,3-dibromobutane.	only (+)	only(-)	meso	(+) and (-)	Answer3	Unit1
35	29	Two hydrogen atoms on second carbon atom of ethanol are __________ in nature	homotopic	heterotopic	non equivalent	homotopic as well as heterotopic	Answer1	Unit1
36	30	________ contains diastereotopic faces.	Acetone	Ethanol	D-glucose	Ethyl chloride	Answer3	Unit1
37	31	Reduction of Pyruvic acid in presence of lactic acid dehydrogenase is an example _____ reaction.	enantioselective	diastereoselective	enantiospecific	diastereospecific	Answer1	Unit1
38	32	Boiling 1-bromo-1,2-diphenylpropane with alcoholic KOH gives ________.	1,1-diphenyl propane	1,1-diphenyl propene	1,2-diphenyl propane	1,2-diphenyl propene	Answer4	Unit1
39	33	Bromination of alkene is an example of ____ addition reaction.	electrophilic	nucleophilic	electrocyclic	nucleocyclic	Answer1	Unit1
40	34	On heating with alcoholic KOH, Erythro-1-bromo-1,2-diphenyl propane gives ______-1,2-diphenyl propene.	cis	trans	cis as well as trans	neither cis nor trans	Answer1	Unit1
41	35	Two faces in 2-butanone are ______________ in nature.	homotopic	heterotopic	neither homotopic nor heterotopic	homotopic as well as heterotopic	Answer2	Unit1
42	36	__________ contains enantiotopic ligands.	Methane	Ethane	Propane	Butane	Answer4	Unit1
43	37	(-)2-bromooctane is treated with dilute NaOH, only (+) 2-octanol is obtained. This is an example of_________ reaction.	enantioselective	diastereoselective	enantiospecific	diastereospecific	Answer3	Unit1
44	38	Reduction of a non-terminal alkyne in presence of hydrogen / Pd to form cis alkene is a_____ reaction.	stereoselective	stereospecific	tereoselective as well as stereospecific	neither stereoselective nor stereospecific	Answer1	Unit1
45	39	Two Hydrogen atoms on first carbon in 2-chloro propene are examples of_________ ligands.	enantiotopic	diastereotopic	homotopic	stereochemically equivalent	Answer2	Unit1
46	40	When two hydrogens in a molecule are replaced by Z one at a time , gives a pair of enantiomers. These hydrogens are called _______ ligands.	enantiotopic	diastereotopic	homotopic	stereochemically equivalent	Answer1	Unit1
47	41	Maleic acid on action of Osmium tetraoxide gives _____ tartaric acid.	meso	(+)	(-)	(+) and (-)	Answer1	Unit1
48	42	A tripeptide contains ______ peptide bonds.	1	2	3	4	Answer2	Unit1
49	43	A polypeptide contains _____ bond also known as peptide bond.	ester	amide	anhydride	ether	Answer2	Unit1
50	44	______ is an example of neutral α- amino acid.	Aspartic acid	Lysine	Glutamic acid	Glycine	Answer4	Unit1
51	45	______ is an example of acidic α- amino acid.	Alanine	Lysine	Glutamic acid	Glycine	Answer3	Unit1
52	46	______ is an example of basic α- amino acid.	Glutamic acid	Glycine	Lysine	Aspartic acid	Answer3	Unit1
53	47	Amino acid containing two amino groups and one carboxylic acid group is called ______ amino acid.	acidic	basic	neutral	acidic as well as basic	Answer2	Unit1
54	48	The pH at which the amino acid does not migrate under the influence of electric field is called _____.	neutralisation point	isoelectric point	saturation point	end point	Answer2	Unit1
55	49	A peptide is a compound formed from two or more ____ linked through peptide linkage.	carboxylic acids	amines	α-amino acids	nitro acids	Answer3	Unit1
56	50	A polypeptide can be synthesised using _______ synthesis.	Strecker	Gabriel’s	Strecker as well as Gabriel’s	Merrifield’s solid phase	Answer4	Unit1
57	51	In Merrifield’s solid phase synthesis _____ is used as solid support.	amino acid	DCC	resin	BOC	Answer3	Unit1
58	52	A zwitter ion contains _______ charge.	only positive	only negative	both positive and negative	neither positive nor negative	Answer3	Unit1
59	53	Alanine contains ____ chiral carbon atom/s.	zero	1	2	3	Answer2	Unit1
60	54	In secondary structure of proteins, the polypeptide chains are held together by _________ bonding between amino group of one chain and carbonyl group of other chain.	covalent	ionic	hydrogen	covalent and ionic	Answer3	Unit1
61	55	Gabriel's phthalimide synthesis of alanine is carried out by reaction between potassium phthalimide and ____.	ethyl α-bromoformate	ethyl α-bromoacetate	ethyl α-bromopropionate	ethyl α-bromobutanoate	Answer3	Unit1
62	56	Tertiary structure of myoglobin shows that it contains _____ helical segments.	zero	one	two	three	Answer4	Unit1
63	57	In Strecker synthesis, aldehyde is reacted with ___.	Ammonia and HCN	HCl and HCN	Ammonia and HCl	ketone and HCN	Answer1	Unit1
64	58	The pI of glycine is ____.	1.24	2.77	5.97	8.23	Answer3	Unit1
65	59	____ is a protecting group for amines.	BOC	Trifluoroacetic acid	DCC	HF	Answer1	Unit1
66	60	______ is used for methionine synthesis by Strecker method.	Acrolein	Acetaldehyde	Acetone	Benzoin	Answer1	Unit1
67	61	Bacitracin is an example of protein which is used as _______.	antibiotic	hormone	steroid	terpenoid	Answer1	Unit1
68	62	In Merrifield solid phase synthesis, _____ is used for deprotecting amino group.	HCl	piperidine	pyridine	Trifluoroacetic acid	Answer4	Unit1
69	63		(a)	(b)	(c)	(d)	Answer 1
70	64	Which of the following reactions involve migration to an electron deficient carbon?	Pinacol-pinacolone	Beckmann	Favorskii	Michael	Answer 1
71	65	Which of the following reactions involve migration to an electron deficient nitrogen?	Beckmann	Favorskii	Pinacol-pinacolone	Michael	Answer 1
72	66	Which of the following rearrangements involve a carbanion?	Pinacol-pinacolone	Beckmann	Favorskii	Michael	Answer 3
73	67	Statement A: Wittig reaction is an organometallic reaction.	Statement A is True and Statement B is False	Statement A is False and Statement B is True	Both statements are True	Both statements are False	Answer 1
74		Statement B: The product of Wittig’s reaction is a substituted alkane.
75	68	Beckmann rearrangement is a …………….. reaction, in which the group that is …………. to the –OH of oxime migrates	stereospecific; anti	stereospecific; syn	stereoselective; anti	stereoselective; syn	Answer 1
76	69	Rearrangement of α-haloketones having ………., in the presence of a basic catalyst to give an acid or acid derivative is called ………. reaction.	α- hydrogen; Pinacol-pinacolone	β- hydrogen; Pinacol-pinacolone	α- hydrogen ; Favorskii	β- hydrogen ; Favorskii	Answer 3
77	70	Acid catalysed rearrangement of a ketoxime to an N-substituted amide is ………...	Favorski rearrangement	Beckmann rearrangement	Pinacol-pinacolone rearrangement	Wittig reaction	Answer 2
78	71		(a)	(b)	(c)	(d)	Answer 1
79	72	Favorskii rearrangement takes place in α-haloketones and proceeds via the formation of a …………. intermediate .	cyclopropane	cyclopropanone	carbocation	carbanion	Answer 2
80	73	Pick the incorrect statement with respect to Pinacol-pinacolone rearrangement:	Pinacols are vicinal diols	It involves rearrangement of carbocation	It requires a basic catalyst	The group that migrates is most nucleophilic	Answer 3
81	74		(a)	(b)	(c)	(d)	Answer 1
82	75	Michael’s reaction is an addition reaction of …………… to ………….	active methylene compound; alkene	carboxylic acid; α,β-unsaturated ketone	carboxylic acid; alkene	active methylene compound; α,β-unsaturated aldehyde	Answer 4
83	76		(a)	(b)	(c)	(d)	Answer 2
84	77	Which of the following reactions involve the formation of an enolate ion as intermediate?	Beckman reaction	Wittig reaction	Pinacol-pinacolone rearrangement	Michael’s addition	Answer 4
85	78	In Wittig reaction a ………. adds to a carbonyl compound to form ……….. as intermediate .	ylide; carbanion	organophosporous compound; carbocation	ylide; betaine	alkene; betaine	Answer 3
86	79		(a)	(b)	(c)	(d)	Answer 3
87	80		(a)	(b)	(c)	(d)	Answer 2
88	81	Wittig reaction involves ………….of ylide to carbonyl compounds	nucleophilic addition	nucleophilic substitution	electrophilic substitution	electrophilic addition	Answer 1
89	82		(a)	(b)	(c)	(d)	Answer 3
90	83	Which of the following reactions proceeds with formation of enolate ion?	Pinacol-pinacolone	Favorskii	Beckmann	Wittig	Answer 2
91	84	…………. is an epimer of D-glucose.	L-glucose	D- mannose	D-fructose	L-mannose	Answer 2
92	85		α-D-glucofuranose	β-D-glucofuranose	β-D-glucopyranose	α-D-glucopyranose	Answer 4
93	86	D-Glucose on treatment with ………….. gives D-Gluconic acid	conc. HNO3	HIO4	NaBH4	Br2-H2O	Answer 4
94	87	Anomer of β-D- glucopyranose is ………… .	α-L- glucopyranose	α-D- glucopyranose	α-D- glucofuranose	α-L- glucofuranose	Answer 2
95	88	D-Galactose is ………….. epimer of D-glucose	C-2	C-3	C-4	C-5	Answer 3
96	89	Chair conformation of………….. is the stablest monosaccharide.	α-D-glucofuranose	β-D-glucofuranose	β-D-glucopyranose	α-D-glucopyranose	Answer 3
97	90	Statement A: Reducing sugars give a black precipitate/silver mirror with Tollen’s reagent. Statement B: Reducing sugars are α- hydroxy aldehydes or ketones	Statement A is True and Statement B is False	Statement A is False and Statement B is True	Both statements are True	Both statements are false	Answer 3
98	91	Arabinose is a ……………	aldopentose	ketopentose	aldohexose	ketohexose	Answer 1
99	92	Monosaccharides exist preferentially in the ………… form.	open chain	acetal/ketal	hemiacetal/hemiketal	linear	Answer 3
100	93	Mutarotation occurs in …………. solvents.	aprotic	amphiprotic	protic	polar	Answer 2