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MSIH Clinical Immunology | Class 2022 | Prof. EC Lewis
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ScheduleClass topicGoals
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UNIT 1
The immune system as a network of pathways and players
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1Sunday198201810:15-13:00IntroductionThe student will be fluent in the anatomy of immune system compartments, as well as innate versus adaptive arms and associated immunocytes; display solid knowledge of major cytokines and chemokines.
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2Sunday268201810:15-11:00 -break- 11:15-12:00 -break- 12:15-13:00Lymphoid system Anatomy and major cell types | Inflammation, innate and adaptive immunity IL-1, IL-2, IL-6, IL-8, TNFa, MCP-1 | MHC class I and II
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UNIT 2
Innate and adaptive immune cell crosstalk
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3Monday39201813:15-14:00 -break- 14:15-15:00 -break- 15:15-16:00Ag presentation MHC I+II : T lymphocytes IFNg, CD28:B7, CD40:CD40L The student will display an understanding of the inter-cellular communication between T and B lymphocytes, innate immunocytes and non-immune cells.
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4Sunday16920188:15-8:35Quiz units 1+2
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-break- 8:45-9:30Cont. B+T lymphocyte interaction | IL-4, germinal center, isotype switching, somatic hypermutation
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UNIT 3
Up close: T lymphocytes
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5179201813:15-16:00Cytotoxic T cells and NK cells; graft immunologyThe student will display an understanding of T cell maturation, immune tolerance and its relation to graft immunology.
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Immune tolerance
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UNIT 4
Up close: The humoral arm of the immune system
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6Sunday1410201810:15-13:00Antibodies, complement systemThe student will display an understanding of the structural and physiological attributes of humoral immunity under physiological conditions.
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Antigens and antibodies
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7Sunday211020188:15-9:30Hypersensitivity and Allergy
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Sunday281020188:15-9:30Quiz units (1+2)+3+4 | Review so far | Article discussion
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UNIT 5
Major Immune system challenges
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8Sunday41120188:15-11:00Host defense I Bacteria, fungiThe student will be able to differentiate between appropriate/inappropriate; wanted/unwanted immune responses in the context autoimmunity, immunodeficiency and transplantation immunology, with relevance to therapeutic clinical decisions; cope with immune-related pathologies that extend beyond the syllabus.
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9Sunday1111201810:15-13:00...viruses, parasites
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Autoimmunity and immunodeficiency
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10Sunday1811201810:15-13:00Immune disorders
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Immunometabolism
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Sunday251120188:15-9:30 (102 Deichman)Mega-Quiz units (1+2+3+4)+5 | Clinical USMLE-style cases | Review lesson
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?122018?Q&A class
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Exam6122018
13:00-16:00 room 206
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Remake?12019
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