| A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | AA | ||
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1 | Malaria Consortium | Malaria Consortium | ||||||||||||||||||||||||||
2 | Burkina Faso | Chad | DRC | DRC | DRC | DRC | Mozambique | Nigeria | Nigeria | Nigeria | Nigeria | Nigeria | Nigeria | Nigeria | Nigeria | Nigeria | Togo | Uganda | ||||||||||
3 | Main calculations | unit | type | Overall | Haut-Katanga | Haut-Lomami | Lualaba | Tanganyika | Nampula | Bauchi | Borno | FCT (Abuja) | Kebbi | Kogi | Nasarawa | Oyo | Plateau | Sokoto | Karamoja | |||||||||
4 | Final cost-effectiveness estimate (pulled from below for visibility) | xbenchmark | feed | - | 18.0 | 8.0 | 7.9 | 9.2 | 9.1 | 12.6 | 11.5 | 21.2 | 18.0 | 16.1 | 29.4 | 21.0 | 22.3 | 24.3 | 16.0 | 29.8 | 10.6 | 10.4 | ||||||
5 | Costs | |||||||||||||||||||||||||||
6 | ||||||||||||||||||||||||||||
7 | GiveWell costs | |||||||||||||||||||||||||||
8 | Grant size | $ | input | $1,000,000 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
9 | ||||||||||||||||||||||||||||
10 | Cost breakdown | |||||||||||||||||||||||||||
11 | Percentage of total costs covered by the grantee | % | input | - | 89% | 89% | 89% | 89% | 89% | 89% | 89% | 86% | 86% | 86% | 86% | 86% | 86% | 86% | 86% | 86% | 87% | 89% | ||||||
12 | Percentage of total costs covered by other philanthropic actors | % | input | - | 1% | 0% | 0% | 0% | 0% | 0% | 0% | 4% | 4% | 4% | 4% | 4% | 4% | 4% | 4% | 4% | 2% | 0% | ||||||
13 | Percentage of total costs covered by domestic governments | % | input | - | 10% | 11% | 11% | 11% | 11% | 11% | 11% | 10% | 10% | 10% | 10% | 10% | 10% | 10% | 10% | 10% | 10% | 11% | ||||||
14 | ||||||||||||||||||||||||||||
15 | Total costs | |||||||||||||||||||||||||||
16 | Total spending by all contributors | $ | calc | - | $1,127,124 | $1,118,119 | $1,118,119 | $1,118,119 | $1,118,119 | $1,118,119 | $1,118,119 | $1,162,185 | $1,162,185 | $1,162,185 | $1,162,185 | $1,162,185 | $1,162,185 | $1,162,185 | $1,162,185 | $1,162,185 | $1,144,056 | $1,118,119 | ||||||
17 | ||||||||||||||||||||||||||||
18 | Total spending attributable to different actors | |||||||||||||||||||||||||||
19 | Total spending contributed by grantee | $ | calc | - | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | ||||||
20 | Total spending contributed by other philanthropic actors | $ | calc | - | $9,161 | $0 | $0 | $0 | $0 | $0 | $0 | $44,631 | $44,631 | $44,631 | $44,631 | $44,631 | $44,631 | $44,631 | $44,631 | $44,631 | $27,990 | $0 | ||||||
21 | Total spending contributed by domestic governments | $ | calc | - | $117,963 | $118,119 | $118,119 | $118,119 | $118,119 | $118,119 | $118,119 | $117,553 | $117,553 | $117,553 | $117,553 | $117,553 | $117,553 | $117,553 | $117,553 | $117,553 | $116,067 | $118,119 | ||||||
22 | ||||||||||||||||||||||||||||
23 | Upstream / downstream spending | |||||||||||||||||||||||||||
24 | Total spending causally upstream of donations to grantee | $ | calc | - | $1,009,161 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,000,000 | $1,044,631 | $1,044,631 | $1,044,631 | $1,044,631 | $1,044,631 | $1,044,631 | $1,044,631 | $1,044,631 | $1,044,631 | $1,027,990 | $1,000,000 | ||||||
25 | Total spending causally downstream of donations to grantee | $ | calc | - | $117,963 | $118,119 | $118,119 | $118,119 | $118,119 | $118,119 | $118,119 | $117,553 | $117,553 | $117,553 | $117,553 | $117,553 | $117,553 | $117,553 | $117,553 | $117,553 | $116,067 | $118,119 | ||||||
26 | ||||||||||||||||||||||||||||
27 | Cost per child covered | |||||||||||||||||||||||||||
28 | Cost per seasonal malaria chemoprevention (SMC) cycle administered | $ | input | - | $1.48 | $1.81 | $1.81 | $1.81 | $1.81 | $1.81 | $1.81 | $1.40 | $1.40 | $1.40 | $1.40 | $1.40 | $1.40 | $1.40 | $1.40 | $1.40 | $1.50 | $1.81 | ||||||
29 | Number of SMC cycles per year | # | input | - | 4.3 | 4.0 | 4.0 | 4.0 | 4.0 | 4.0 | 4.0 | 4.0 | 4.0 | 5.0 | 4.0 | 5.0 | 5.0 | 5.0 | 5.0 | 4.0 | 4.0 | 5.0 | ||||||
30 | Total cost per child treated with all cycles of SMC in a year | $ | calc | - | $6.35 | $7.24 | $7.24 | $7.24 | $7.24 | $7.24 | $7.24 | $5.61 | $5.61 | $7.01 | $5.61 | $7.01 | $7.01 | $7.01 | $7.01 | $5.61 | $5.98 | $9.05 | ||||||
31 | Upstream costs per child treated with all cycles of SMC in a year | $ | calc | - | $5.69 | $6.48 | $6.48 | $6.48 | $6.48 | $6.48 | $6.48 | $5.04 | $5.04 | $6.30 | $5.04 | $6.30 | $6.30 | $6.30 | $6.30 | $5.04 | $5.37 | $8.09 | ||||||
32 | ||||||||||||||||||||||||||||
33 | Outputs | |||||||||||||||||||||||||||
34 | ||||||||||||||||||||||||||||
35 | Total children covered | |||||||||||||||||||||||||||
36 | Total people under age 5 receiving a year of SMC | # | calc | - | 175,783 | 154,429 | 154,429 | 154,429 | 154,429 | 154,429 | 154,429 | 198,305 | 198,305 | 158,644 | 198,305 | 158,644 | 158,644 | 158,644 | 158,644 | 198,305 | 186,096 | 123,544 | ||||||
37 | ||||||||||||||||||||||||||||
38 | Outcomes | |||||||||||||||||||||||||||
39 | ||||||||||||||||||||||||||||
40 | Mortality reduction among people under age 5 (treated population) | |||||||||||||||||||||||||||
41 | Reduction in malaria incidence for children under age 5 targeted for SMC found in GiveWell's adjusted version of the Meremikwu et al. 2012 meta-analysis | % | input | 75% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
42 | Estimated proportion of children targeted for SMC in trials that received SMC | % | input | 90% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
43 | Implied reduction in malaria incidence among children under age 5 receiving SMC | % | calc | 84% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
44 | Internal validity adjustment | % | input | -5% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
45 | External validity adjustment | % | input | 0% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
46 | Adjustment for lower effectiveness outside the Sahel region of Africa | % | input | - | 0% | 0% | -20% | -20% | -20% | -20% | -20% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | -20% | ||||||
47 | Expected reduction in malaria incidence among children under age 5 receiving SMC | % | calc | - | 79% | 79% | 64% | 64% | 64% | 64% | 64% | 79% | 79% | 79% | 79% | 79% | 79% | 79% | 79% | 79% | 79% | 64% | ||||||
48 | Ratio of the reduction in malaria mortality to the reduction in malaria incidence | % | input | 100% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
49 | Expected reduction in malaria mortality among children under age 5 receiving SMC | % | calc | - | 79% | 79% | 64% | 64% | 64% | 64% | 64% | 79% | 79% | 79% | 79% | 79% | 79% | 79% | 79% | 79% | 79% | 64% | ||||||
50 | Annual malaria mortality rate among 3-59-month-olds | % | supp | - | 0.38% | 0.13% | 0.18% | 0.22% | 0.22% | 0.33% | 0.28% | 0.24% | 0.16% | 0.17% | 0.31% | 0.21% | 0.27% | 0.22% | 0.19% | 0.34% | 0.16% | 0.31% | ||||||
51 | Indirect malaria deaths per direct malaria death | # | input | 0.75 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
52 | Total malaria-attributable mortality rate (including direct and indirect malaria deaths) | % | calc | - | 0.67% | 0.22% | 0.32% | 0.38% | 0.38% | 0.57% | 0.49% | 0.43% | 0.29% | 0.30% | 0.55% | 0.37% | 0.48% | 0.39% | 0.33% | 0.60% | 0.28% | 0.54% | ||||||
53 | Expected number of annual malaria-attributable mortalities among the target population in the absence of SMC | # | calc | - | 1,183 | 347 | 497 | 589 | 585 | 879 | 750 | 845 | 570 | 483 | 1,086 | 587 | 754 | 619 | 523 | 1,192 | 521 | 668 | ||||||
54 | Proportion of annual malaria mortality that occurs during the SMC season | % | input | - | 70% | 70% | 52% | 52% | 52% | 52% | 52% | 70% | 70% | 70% | 70% | 70% | 70% | 70% | 70% | 70% | 70% | 62% | ||||||
55 | Expected number of malaria-attributable mortalities among the target population during the SMC season in the absence of SMC | # | calc | - | 828 | 243 | 256 | 303 | 301 | 453 | 386 | 591 | 399 | 338 | 760 | 411 | 528 | 433 | 366 | 834 | 365 | 414 | ||||||
56 | Total deaths averted among people under age 5 | # | calc | - | 657 | 193 | 163 | 194 | 192 | 289 | 247 | 469 | 317 | 268 | 604 | 326 | 419 | 344 | 291 | 662 | 289 | 264 | ||||||
57 | ||||||||||||||||||||||||||||
58 | Mortality reduction among people over age 5 (untreated population) | |||||||||||||||||||||||||||
59 | Reduction in malaria incidence among the SMC-eligible population found in Cisse et al. 2016 | % | input | 60% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
60 | Reduction in malaria incidence among the population too old to be eligible for SMC found in Cisse et al. 2016 | % | input | 26% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
61 | Implied proportion of the protective effect of SMC received by the population too old to be eligible for SMC | % | calc | 43% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
62 | Adjustment for differences in program coverage and transmission intensity in the populations studied by the Cisse et al. 2016 trial and the populations targeted by grantee programs | % | input | -69% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
63 | Expected proportion of the protective effect of SMC received by the population too old to be eligible for SMC | % | calc | 13% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
64 | Expected reduction in malaria incidence among people over age 5 | % | calc | - | 11% | 11% | 9% | 9% | 9% | 9% | 9% | 11% | 11% | 11% | 11% | 11% | 11% | 11% | 11% | 11% | 11% | 9% | ||||||
65 | Ratio of the reduction in malaria mortality to the reduction in malaria incidence | % | feed | 100% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
66 | Expected reduction in malaria mortality among people over age 5 | % | calc | - | 11% | 11% | 9% | 9% | 9% | 9% | 9% | 11% | 11% | 11% | 11% | 11% | 11% | 11% | 11% | 11% | 11% | 9% | ||||||
67 | Malaria mortalities among people over age 5 per malaria mortality among 3-59-month-olds | # | supp | - | 0.7 | 0.7 | 0.3 | 0.3 | 0.3 | 0.3 | 1.5 | 0.3 | 0.9 | 1.5 | 0.5 | 2.4 | 1.1 | 3.3 | 1.3 | 0.3 | 2.1 | 0.3 | ||||||
68 | Expected number of malaria-attributable mortalities among the target population during the SMC season in the absence of SMC | # | calc | - | 555 | 159 | 89 | 105 | 104 | 157 | 577 | 164 | 351 | 516 | 376 | 973 | 563 | 1,416 | 477 | 237 | 765 | 143 | ||||||
69 | Total deaths averted among people age 5 and older | # | calc | - | 59 | 17 | 8 | 9 | 9 | 13 | 49 | 17 | 37 | 55 | 40 | 103 | 60 | 150 | 51 | 25 | 81 | 12 | ||||||
70 | ||||||||||||||||||||||||||||
71 | Malaria incidence reduction among people under age 15 | |||||||||||||||||||||||||||
72 | Adjusted malaria incidence among people age 1 to 4 | % | supp | - | 60% | 37% | 31% | 37% | 35% | 35% | 36% | 45% | 47% | 53% | 82% | 72% | 85% | 124% | 60% | 66% | 79% | 35% | ||||||
73 | Adjusted malaria incidence among people age 5 to 14 | % | supp | - | 25% | 16% | 31% | 37% | 35% | 35% | 36% | 19% | 20% | 20% | 32% | 28% | 32% | 46% | 24% | 27% | 31% | 35% | ||||||
74 | Expected reduction in malaria incidence among people age 1 to 4 | ppt | calc | - | 33% | 21% | 10% | 12% | 12% | 12% | 12% | 25% | 26% | 29% | 45% | 40% | 47% | 69% | 34% | 37% | 44% | 14% | ||||||
75 | Expected reduction in malaria incidence among people age 5 to 14 | ppt | calc | - | 2% | 1% | 1% | 2% | 2% | 2% | 2% | 1% | 1% | 2% | 2% | 2% | 2% | 3% | 2% | 2% | 2% | 2% | ||||||
76 | National population age 1 to 4 | # | input | - | 3,159,820 | 2,593,740 | 10,821,149 | 10,821,149 | 10,821,149 | 10,821,149 | 4,037,237 | 26,401,071 | 26,401,071 | 26,401,071 | 26,401,071 | 26,401,071 | 26,401,071 | 26,401,071 | 26,401,071 | 26,401,071 | 887,125 | 5,581,405 | ||||||
77 | National population age 5 to 14 | # | input | - | 6,348,446 | 4,977,421 | 24,065,680 | 24,065,680 | 24,065,680 | 24,065,680 | 8,658,113 | 60,226,437 | 60,226,437 | 60,226,437 | 60,226,437 | 60,226,437 | 60,226,437 | 60,226,437 | 60,226,437 | 60,226,437 | 2,032,781 | 11,987,722 | ||||||
78 | Number of 5-14-year-olds exposed to spillover effects per person targeted to receive SMC | # | calc | - | 2.0 | 1.9 | 2.2 | 2.2 | 2.2 | 2.2 | 2.1 | 2.3 | 2.3 | 2.3 | 2.3 | 2.3 | 2.3 | 2.3 | 2.3 | 2.3 | 2.3 | 2.1 | ||||||
79 | Total 5-14-year-olds exposed to spillover effects from SMC | # | calc | - | 353,169 | 296,352 | 343,443 | 343,443 | 343,443 | 343,443 | 331,184 | 452,376 | 452,376 | 361,901 | 452,376 | 361,901 | 361,901 | 361,901 | 361,901 | 452,376 | 426,425 | 265,346 | ||||||
80 | Malaria cases averted among people under age 5 | # | calc | - | 58,657 | 32,109 | 15,605 | 19,015 | 17,957 | 17,824 | 18,446 | 49,886 | 51,503 | 46,623 | 89,876 | 63,791 | 75,191 | 109,095 | 53,301 | 72,828 | 81,790 | 16,883 | ||||||
81 | Malaria cases averted among people age 5 to 14 | # | calc | - | 6,482 | 3,574 | 4,643 | 5,658 | 5,343 | 5,303 | 5,292 | 6,259 | 6,639 | 5,447 | 10,796 | 7,619 | 8,568 | 12,442 | 6,432 | 9,162 | 9,777 | 4,851 | ||||||
82 | ||||||||||||||||||||||||||||
83 | Long-term income increases for people under age 15 | |||||||||||||||||||||||||||
84 | Increase in annual income per malaria case averted among people under age 15 | % | input | 0.6% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
85 | Adjusted increase in ln(income) per malaria case averted among people under age 15 | ln($) | calc | 0.006 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
86 | Average number of years between receiving SMC and the beginning of long-term benefits | # | input | 12.5 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
87 | Discount rate for future benefits | % | input | 4.0% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
88 | Discounted increase in ln(income) per malaria case averted among people under age 15 | ln($) | calc | 0.004 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
89 | Expected number of years the long-term benefits of receiving SMC will last | # | input | 40 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
90 | Present value of individual lifetime benefits per malaria case averted among people under age 15 | ln($) | calc | 0.08 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
91 | Multiplier for resource sharing within households | # | input | 2 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
92 | Present value of total lifetime benefits per malaria case averted among people under age 15 | ln($) | calc | 0.16 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||
93 | Present value of increase in units of annual ln(income) among people under age 5 | ln($) | calc | - | 9,515 | 5,209 | 2,531 | 3,085 | 2,913 | 2,891 | 2,992 | 8,093 | 8,355 | 7,563 | 14,580 | 10,348 | 12,198 | 17,697 | 8,646 | 11,814 | 13,268 | 2,739 | ||||||
94 | Present value of increase in units of annual ln(income) among people age 5 to 14 | ln($) | calc | - | 1,052 | 580 | 753 | 918 | 867 | 860 | 859 | 1,015 | 1,077 | 884 | 1,751 | 1,236 | 1,390 | 2,018 | 1,043 | 1,486 | 1,586 | 787 | ||||||
95 | Total present value of units of increase in units of annual ln(income) among people under age 15 | ln($) | calc | - | 10,567 | 5,788 | 3,285 | 4,002 | 3,780 | 3,752 | 3,851 | 9,108 | 9,432 | 8,447 | 16,331 | 11,584 | 13,588 | 19,716 | 9,690 | 13,300 | 14,854 | 3,526 | ||||||
96 | ||||||||||||||||||||||||||||
97 | Value of outcomes | |||||||||||||||||||||||||||
98 | ||||||||||||||||||||||||||||
99 | Units of value from mortality reduction among people under age 5 | |||||||||||||||||||||||||||
100 | Value assigned to averting a malaria-attributable death of a person under age 5 | UoV | input | 116 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||