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1 | Suggested action (by annotation review requester) | COMMENT (FIXED /OK) - by Contributor | Git handle of respondent | assigned_by | bioentity | bioentity_label | reference | qualifier | annotation_class | annotation_class_label | evidence_type | evidence_with | bioentity_isoform | panther_family | date | annotation_extension_class | taxon | ||||||||||
2 | EXTENSION | Changed | RLovering | ARUK-UCL | RGD:621681 | P2ry12 | PMID:17299767|RGD:13673751 | GO:0051897 | positive regulation of protein kinase B signaling | IMP | PANTHER:PTHR24233 | 20211119 | CL:0000129|GO:0071318|GO:0021808|GO:0035585 | NCBITaxon:10116 | |||||||||||||
3 | Changed | RLovering | ARUK-UCL | RGD:621681 | P2ry12 | PMID:17299767|RGD:13673751 | GO:0021808 | cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration | IMP | PANTHER:PTHR24233 | 20180523 | CL:0000129 | NCBITaxon:10116 | ||||||||||||||
4 | EXTENSION | Changed | RLovering | ARUK-UCL | RGD:621681 | P2ry12 | PMID:18183622|RGD:13673786 | GO:0007200 | phospholipase C-activating G protein-coupled receptor signaling pathway | IMP | PANTHER:PTHR24233 | 20180523 | GO:0071415|CL:0000129|GO:0021808|GO:0043491 | NCBITaxon:10116 | |||||||||||||
5 | EXTENSION | Changed | RLovering | ARUK-UCL | RGD:621681 | P2ry12 | PMID:18183622|RGD:13673786 | GO:0050921 | positive regulation of chemotaxis | IMP | PANTHER:PTHR24233 | 20180523 | GO:0071415|CL:0000129|GO:0021808|GO:0043552 | NCBITaxon:10116 | |||||||||||||
6 | EXTENSION | Changed | RLovering | ARUK-UCL | RGD:621681 | P2ry12 | PMID:18183622|RGD:13673786 | GO:1904141 | positive regulation of microglial cell migration | IMP | PANTHER:PTHR24233 | 20180523 | GO:0071415|CL:0000129|GO:0021808|GO:0050921|GO:0043552 | NCBITaxon:10116 | |||||||||||||
7 | Changed | RLovering | ARUK-UCL | RGD:621681 | P2ry12 | PMID:18183622|RGD:13673786 | GO:0021808 | cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration | IMP | PANTHER:PTHR24233 | 20180523 | GO:0071415|CL:0000129 | NCBITaxon:10116 | ||||||||||||||
8 | Changed | RLovering | ARUK-UCL | MGI:MGI:104574 | Ptprj | PMID:18249142|MGI:MGI:3774343 | GO:1905451 | positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis | IGI | UniProtKB:P06800 | PANTHER:PTHR19134 | 20180725 | CL:0002476|CL:0002476 | NCBITaxon:10090 | |||||||||||||
9 | Changed | RLovering | ARUK-UCL | MGI:MGI:97810 | Ptprc | PMID:18249142|MGI:MGI:3774343 | GO:1905451 | positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis | IGI | UniProtKB:Q64455 | PANTHER:PTHR19134 | 20180725 | CL:0002476|CL:0002476 | NCBITaxon:10090 | |||||||||||||
10 | Changed | RLovering | ARUK-UCL | RGD:2308 | Cd47 | PMID:21401967|RGD:13792533 | GO:1905450 | negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis | IMP | PANTHER:PTHR10613 | 20180726 | CL:0000129|CL:0000129|CL:0000235|CL:0000235 | NCBITaxon:10116 | ||||||||||||||
11 | Changed | RLovering | ARUK-UCL | UniProtKB:P31994 | FCGR2B | PMID:2142460 | GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | IDA | PANTHER:PTHR11481 | 20170614 | NCBITaxon:9606 | |||||||||||||||
12 | EXTENSION | Changed | RLovering | ARUK-UCL | MGI:MGI:88227 | C3 | PMID:22632727|MGI:MGI:6189359 | GO:0060100 | positive regulation of phagocytosis, engulfment | IMP | PANTHER:PTHR11412 | 20180627 | CL:0000129|CL:0000129|GO:1905114|EMAPA:35290|UBERON:0009953 | NCBITaxon:10090 | |||||||||||||
13 | EXTENSION | Changed | RLovering | ARUK-UCL | MGI:MGI:96607 | Itgam | PMID:22632727|MGI:MGI:6189359 | GO:0006911 | phagocytosis, engulfment | IMP | PANTHER:PTHR23220 | 20181108 | CL:0000129|GO:1905114|EMAPA:35290|UBERON:0009953 | NCBITaxon:10090 | |||||||||||||
14 | Changed | RLovering | ARUK-UCL | MGI:MGI:88227 | C3 | PMID:22632727|MGI:MGI:6189359 | GO:1905114 | cell surface receptor signaling pathway involved in cell-cell signaling | IMP | PANTHER:PTHR11412 | 20210428 | CL:0000129|EMAPA:35290|UBERON:0009953 | NCBITaxon:10090 | ||||||||||||||
15 | Changed | RLovering | ARUK-UCL | MGI:MGI:96607 | Itgam | PMID:22632727|MGI:MGI:6189359 | GO:1905114 | cell surface receptor signaling pathway involved in cell-cell signaling | IMP | PANTHER:PTHR23220 | 20210428 | CL:0000129|EMAPA:35290|UBERON:0009953 | NCBITaxon:10090 | ||||||||||||||
16 | Changed | RLovering | ARUK-UCL | RNAcentral:URS0000134ADC_9606 | URS0000134ADC_9606 | PMID:24023731 | GO:1905241 | positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation | IMP | 20210702 | GO:0072497|CL:0002540 | NCBITaxon:9606 | |||||||||||||||
17 | Changed | RLovering | ARUK-UCL | UniProtKB:P35222 | CTNNB1 | PMID:24023731 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation | IMP | PANTHER:PTHR45976 | 20210702 | CL:0002540|GO:0072497 | NCBITaxon:9606 | ||||||||||||||
18 | Changed | RLovering | ARUK-UCL | UniProtKB:P49841 | GSK3B | PMID:24023731 | GO:1905240 | negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation | IMP | PANTHER:PTHR24057 | 20210702 | CL:0002540|GO:2000740 | NCBITaxon:9606 | ||||||||||||||
19 | Changed | RLovering | BHF-UCL | MGI:MGI:88276 | Ctnnb1 | PMID:12464179|MGI:MGI:2446944 | GO:0061324 | canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation | IMP | PANTHER:PTHR45976 | 20111012 | NCBITaxon:10090 | |||||||||||||||
20 | Changed | RLovering | BHF-UCL | MGI:MGI:97363 | Notch1 | PMID:14701881|MGI:MGI:3027664 | GO:0061314 | Notch signaling involved in heart development | IMP | PANTHER:PTHR45836 | 20120727 | NCBITaxon:10090 | |||||||||||||||
21 | Changed | RLovering | BHF-UCL | ZFIN:ZDB-GENE-030131-8788 | ncln | PMID:15257293|ZFIN:ZDB-PUB-040719-9 | GO:1900176 | negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | IMP | PANTHER:PTHR31826 | 20120517 | NCBITaxon:7955 | |||||||||||||||
22 | Changed | RLovering | BHF-UCL | ZFIN:ZDB-GENE-040826-3 | nomo | PMID:15257293|ZFIN:ZDB-PUB-040719-9 | GO:1900176 | negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | IMP | PANTHER:PTHR23303 | 20160121 | NCBITaxon:7955 | |||||||||||||||
23 | Changed | RLovering | BHF-UCL | MGI:MGI:1859388 | Dll4 | PMID:15466159|MGI:MGI:3056036 | GO:0061314 | Notch signaling involved in heart development | IMP | PANTHER:PTHR24044 | 20120730 | NCBITaxon:10090 | |||||||||||||||
24 | Changed | RLovering | BHF-UCL | MGI:MGI:1306784 | Cited2 | PMID:15475956|MGI:MGI:3054669 | GO:1900164 | nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | IMP | PANTHER:PTHR17045 | 20120517 | NCBITaxon:10090 | |||||||||||||||
25 | Changed | RLovering | BHF-UCL | UniProtKB:P46531 | NOTCH1 | PMID:16025100 | GO:0061314 | Notch signaling involved in heart development | IMP | PANTHER:PTHR45836 | 20120806 | NCBITaxon:9606 | |||||||||||||||
26 | Changed | RLovering | BHF-UCL | UniProtKB:P35222 | CTNNB1 | PMID:17072303 | GO:0044334 | canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition | IMP | PANTHER:PTHR45976 | 20100930 | NCBITaxon:9606 | |||||||||||||||
27 | Changed | RLovering | BHF-UCL | UniProtKB:Q9NQB0 | TCF7L2 | PMID:17072303 | GO:0044334 | canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition | IMP | PANTHER:PTHR10373 | 20100930 | NCBITaxon:9606 | |||||||||||||||
28 | Changed | RLovering | BHF-UCL | UniProtKB:Q15796 | SMAD2 | PMID:17239842 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | IMP | PANTHER:PTHR13703 | 20120322 | NCBITaxon:9606 | |||||||||||||||
29 | Changed | RLovering | BHF-UCL | Xenbase:XB-GENE-865412 | dand5.S | PMID:17239842 | GO:1900146 | negative regulation of nodal signaling pathway involved in determination of left/right asymmetry | IMP | 20120322 | NCBITaxon:8355 | ||||||||||||||||
30 | Changed | RLovering | BHF-UCL | Xenbase:XB-GENE-865693 | gdf3.S | PMID:17239842 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | IMP | 20120322 | NCBITaxon:8355 | ||||||||||||||||
31 | EXTENSION | Changed | RLovering | BHF-UCL | UniProtKB:P23634 | ATP2B4 | PMID:17242280 | GO:0036487 | nitric-oxide synthase inhibitor activity | IDA | PANTHER:PTHR24093 | 20180223 | GO:0098736|GO:0086023 | NCBITaxon:9606 | |||||||||||||
32 | EXTENSION | Changed | RLovering | BHF-UCL | UniProtKB:P23634 | ATP2B4 | PMID:17242280 | GO:0051001 | negative regulation of nitric-oxide synthase activity | IDA | PANTHER:PTHR24093 | 20180223 | GO:0086023|GO:0098736 | NCBITaxon:9606 | |||||||||||||
33 | Changed | RLovering | BHF-UCL | UniProtKB:P23634 | ATP2B4 | PMID:17242280 | GO:0140199 | negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process | IDA | PANTHER:PTHR24093 | 20180223 | NCBITaxon:9606 | |||||||||||||||
34 | Changed | RLovering | BHF-UCL | MGI:MGI:97360 | Nos1 | PMID:17242280|MGI:MGI:3771112 | GO:0140196 | positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process | IMP | PANTHER:PTHR19384 | 20180223 | NCBITaxon:10090 | |||||||||||||||
35 | Changed | RLovering | BHF-UCL | MGI:MGI:1341800 | Hey1 | PMID:17259303|MGI:MGI:3703467 | GO:0061314 | Notch signaling involved in heart development | IMP | PANTHER:PTHR10985 | 20220823 | NCBITaxon:10090 | |||||||||||||||
36 | Changed | RLovering | BHF-UCL | MGI:MGI:107543 | Sox17 | PMID:17360443|MGI:MGI:3703823 | GO:0003308 | negative regulation of Wnt signaling pathway involved in heart development | IMP | PANTHER:PTHR10270 | 20110713 | NCBITaxon:10090 | |||||||||||||||
37 | Changed | rlovering | BHF-UCL | UniProtKB:Q9PWB0 | CER1 | PMID:17507406 | GO:1900176 | negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | IDA | PANTHER:PTHR15273 | 20120322 | NCBITaxon:9031 | |||||||||||||||
38 | Changed | RLovering | BHF-UCL | MGI:MGI:97359 | Nodal | PMID:17507406|MGI:MGI:5315339 | GO:1900164 | nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | IMP | PANTHER:PTHR11848 | 20120322 | NCBITaxon:10090 | |||||||||||||||
39 | Changed | RLovering | BHF-UCL | MGI:MGI:1923615 | Tbx18 | PMID:17584735|MGI:MGI:3722519 | GO:0060829 | negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation | IDA | PANTHER:PTHR11267 | 20110704 | NCBITaxon:10090 | |||||||||||||||
40 | Changed | RLovering | BHF-UCL | UniProtKB:P46531 | NOTCH1 | PMID:17662764 | GO:0061314 | Notch signaling involved in heart development | IMP | PANTHER:PTHR45836 | 20120730 | NCBITaxon:9606 | |||||||||||||||
41 | Changed | RLovering | BHF-UCL | UniProtKB:P12643 | BMP2 | PMID:18545679 | GO:0003308 | negative regulation of Wnt signaling pathway involved in heart development | IDA | PANTHER:PTHR11848 | 20120220 | NCBITaxon:9606 | |||||||||||||||
42 | Changed | RLovering | BHF-UCL | MGI:MGI:107785 | Mesp1 | PMID:18593560|MGI:MGI:4441249 | GO:0035481 | positive regulation of Notch signaling pathway involved in heart induction | IDA | PANTHER:PTHR20937 | 20100505 | NCBITaxon:10090 | |||||||||||||||
43 | Changed | RLovering | BHF-UCL | ZFIN:ZDB-GENE-040812-2 | caprin2 | PMID:18762581|ZFIN:ZDB-PUB-080908-2 | GO:2000055 | positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification | IMP | PANTHER:PTHR22922 | 20110203 | NCBITaxon:7955 | |||||||||||||||
44 | Changed | RLovering | BHF-UCL | ZFIN:ZDB-GENE-980526-332 | wnt8a | PMID:18762581|ZFIN:ZDB-PUB-080908-2 | GO:0044332 | Wnt signaling pathway involved in dorsal/ventral axis specification | IMP | PANTHER:PTHR12027 | 20110203 | NCBITaxon:7955 | |||||||||||||||
45 | Changed | RLovering | BHF-UCL | UniProtKB:O14641 | DVL2 | PMID:18787224 | GO:0044340 | canonical Wnt signaling pathway involved in regulation of cell proliferation | IDA | PANTHER:PTHR10878 | 20100930 | NCBITaxon:9606 | |||||||||||||||
46 | Changed | RLovering | BHF-UCL | Xenbase:XB-GENE-865575 | wnt6.S | PMID:18804460 | GO:0003306 | Wnt signaling pathway involved in heart development | IMP | 20100708 | NCBITaxon:8355 | ||||||||||||||||
47 | Changed | RLovering | BHF-UCL | UniProtKB:Q5T4F7 | SFRP5 | PMID:18981481 | GO:2000057 | negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis | IMP | PANTHER:PTHR11309 | 20110822 | NCBITaxon:9606 | |||||||||||||||
48 | Changed | RLovering | BHF-UCL | Xenbase:XB-GENE-866281 | wnt8a.L | PMID:18997112 | GO:0044335 | canonical Wnt signaling pathway involved in neural crest cell differentiation | IMP | 20100930 | NCBITaxon:8355 | ||||||||||||||||
49 | Changed | RLovering | BHF-UCL | MGI:MGI:103580 | Hand2 | PMID:19008477|MGI:MGI:4413411 | GO:2000764 | positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis | IMP | PANTHER:PTHR23349 | 20120119 | NCBITaxon:10090 | |||||||||||||||
50 | Changed | RLovering | BHF-UCL | RNAcentral:URS00001DC04F_9606 | URS00001DC04F_9606 | PMID:19131648 | GO:0086094 | positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction | IDA | 20160304 | CL:0000746 | NCBITaxon:9606 | |||||||||||||||
51 | Changed | RLovering | BHF-UCL | MGI:MGI:1095416 | Jag1 | PMID:19509466|MGI:MGI:4359139 | GO:0061314 | Notch signaling involved in heart development | IMP | PANTHER:PTHR24044 | 20120813 | NCBITaxon:10090 | |||||||||||||||
52 | Changed | RLovering | BHF-UCL | MGI:MGI:97363 | Notch1 | PMID:20007915|MGI:MGI:4947514 | GO:0061314 | Notch signaling involved in heart development | IMP | PANTHER:PTHR45836 | 20120730 | NCBITaxon:10090 | |||||||||||||||
53 | Changed | RLovering | BHF-UCL | UniProtKB:P56703 | WNT3 | PMID:20039315 | GO:0044338 | canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation | IMP | PANTHER:PTHR12027 | 20100930 | NCBITaxon:9606 | |||||||||||||||
54 | Changed | RLovering | BHF-UCL | UniProtKB:P56703 | WNT3 | PMID:20039315 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation | IMP | PANTHER:PTHR12027 | 20100930 | NCBITaxon:9606 | |||||||||||||||
55 | Changed | RLovering | BHF-UCL | UniProtKB:Q9UP38 | FZD1 | PMID:20039315 | GO:0044338 | canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation | IMP | PANTHER:PTHR11309 | 20100930 | NCBITaxon:9606 | |||||||||||||||
56 | Changed | RLovering | BHF-UCL | UniProtKB:Q9UP38 | FZD1 | PMID:20039315 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation | IMP | PANTHER:PTHR11309 | 20100930 | NCBITaxon:9606 | |||||||||||||||
57 | Changed | RLovering | BHF-UCL | Xenbase:XB-GENE-865412 | dand5.S | PMID:20381352 | GO:1900146 | negative regulation of nodal signaling pathway involved in determination of left/right asymmetry | IMP | 20120322 | NCBITaxon:8355 | ||||||||||||||||
58 | Changed | RLovering | BHF-UCL | Xenbase:XB-GENE-865681 | nodal1.L | PMID:20381352 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | IMP | 20120322 | NCBITaxon:8355 | ||||||||||||||||
59 | Changed | RLovering | BHF-UCL | UniProtKB:P78504 | JAG1 | PMID:20437614 | GO:0061314 | Notch signaling involved in heart development | IMP | PANTHER:PTHR24044 | 20120730 | NCBITaxon:9606 | |||||||||||||||
60 | Changed | RLovering | BHF-UCL | UniProtKB:O94907 | DKK1 | PMID:20559569 | GO:1901296 | negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | IDA | PANTHER:PTHR12113 | 20120821 | NCBITaxon:9606 | |||||||||||||||
61 | Changed | RLovering | BHF-UCL | UniProtKB:P56704 | WNT3A | PMID:20559569 | GO:0061317 | canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | IDA | PANTHER:PTHR12027 | 20120821 | NCBITaxon:9606 | |||||||||||||||
62 | Changed | RLovering | BHF-UCL | UniProtKB:Q9H1J5 | WNT8A | PMID:20559569 | GO:0061317 | canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | IEP | PANTHER:PTHR12027 | 20120821 | NCBITaxon:9606 | |||||||||||||||
63 | Changed | RLovering | BHF-UCL | MGI:MGI:97363 | Notch1 | PMID:20890042|MGI:MGI:4837019 | GO:0061314 | Notch signaling involved in heart development | IGI | UniProtKB:Q02085 | PANTHER:PTHR45836 | 20120727 | NCBITaxon:10090 | ||||||||||||||
64 | Changed | RLovering | BHF-UCL | MGI:MGI:98330 | Snai1 | PMID:20890042|MGI:MGI:4837019 | GO:0061314 | Notch signaling involved in heart development | IGI | UniProtKB:Q01705 | PANTHER:PTHR24388 | 20120727 | NCBITaxon:10090 | ||||||||||||||
65 | Changed | RLovering | BHF-UCL | MGI:MGI:1932386 | Ift122 | PMID:21209331|MGI:MGI:4888042 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning | IMP | PANTHER:PTHR12764 | 20140317 | NCBITaxon:10090 | |||||||||||||||
66 | Changed | RLovering | BHF-UCL | MGI:MGI:1098271 | Rgs2 | PMID:21291891|MGI:MGI:5009116 | GO:0140194 | negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process | IMP | PANTHER:PTHR10845 | 20180224 | NCBITaxon:10090 | |||||||||||||||
67 | Changed | RLovering | BHF-UCL | UniProtKB:Q06330 | RBPJ | PMID:21311046 | GO:0061314 | Notch signaling involved in heart development | IMP | PANTHER:PTHR10665 | 20220315 | NCBITaxon:9606 | |||||||||||||||
68 | Changed | RLovering | BHF-UCL | MGI:MGI:109497 | Gata5 | PMID:21633169|MGI:MGI:5286818 | GO:0035481 | positive regulation of Notch signaling pathway involved in heart induction | IMP | PANTHER:PTHR10071 | 20180511 | NCBITaxon:10090 | |||||||||||||||
69 | Changed | RLovering | BHF-UCL | MGI:MGI:106206 | Nrp1 | PMID:21658587|MGI:MGI:5141569 | GO:1902378 | VEGF-activated neuropilin signaling pathway involved in axon guidance | IMP | PANTHER:PTHR46806 | 20140512 | CL:0000740 | NCBITaxon:10090 | ||||||||||||||
70 | Changed | RLovering | BHF-UCL | MGI:MGI:99557 | Pde4b | PMID:21670503|MGI:MGI:5286798 | GO:0140199 | negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process | IMP | PANTHER:PTHR11347 | 20180517 | GO:0086004 | NCBITaxon:10090 | ||||||||||||||
71 | Changed | RLovering | BHF-UCL | MGI:MGI:109244 | Sema4d | PMID:22019888|MGI:MGI:5297297 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis | IMP | PANTHER:PTHR11036 | 20120822 | NCBITaxon:10090 | |||||||||||||||
72 | Changed | RLovering | BHF-UCL | MGI:MGI:2154238 | Plxnb1 | PMID:22019888|MGI:MGI:5297297 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis | IMP | PANTHER:PTHR22625 | 20120822 | NCBITaxon:10090 | |||||||||||||||
73 | EXTENSION ontology review required | RLovering | BHF-UCL | MGI:MGI:102541 | Tbx5 | PMID:22728936|MGI:MGI:5449667 | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IDA | PANTHER:PTHR11267 | 20210511 | UniProtKB:Q9JJV9|UBERON:0004146|GO:0086019|UniProtKB:Q01231|UBERON:0004146|GO:1903598 | NCBITaxon:10090 | ||||||||||||||
74 | EXTENSION ontology review required | RLovering | BHF-UCL | MGI:MGI:102541 | Tbx5 | PMID:22728936|MGI:MGI:5449667 | GO:0045944 | positive regulation of transcription by RNA polymerase II | IDA | PANTHER:PTHR11267 | 20210511 | UniProtKB:Q9JJV9|UBERON:0004146|GO:0086019|UniProtKB:Q9JJV9|GO:0060371|UniProtKB:Q01231|UBERON:0004146|GO:1903598 | NCBITaxon:10090 | ||||||||||||||
75 | ontology review required | RLovering | BHF-UCL | MGI:MGI:102541 | Tbx5 | PMID:22728936|MGI:MGI:5449667 | GO:0086019 | cell-cell signaling involved in cardiac conduction | IGI | UniProtKB:Q9JJV9 | PANTHER:PTHR11267 | 20210205 | UBERON:0004146 | NCBITaxon:10090 | |||||||||||||
76 | Changed | RLovering | BHF-UCL | MGI:MGI:106206 | Nrp1 | PMID:22790009|MGI:MGI:5437554 | GO:1902285 | semaphorin-plexin signaling pathway involved in neuron projection guidance | IMP | PANTHER:PTHR46806 | 20130723 | NCBITaxon:10090 | |||||||||||||||
77 | Changed | RLovering | BHF-UCL | MGI:MGI:107558 | Sema3a | PMID:22790009|MGI:MGI:5437554 | GO:1902285 | semaphorin-plexin signaling pathway involved in neuron projection guidance | IMP | PANTHER:PTHR11036 | 20130723 | NCBITaxon:10090 | |||||||||||||||
78 | Changed | RLovering | BHF-UCL | MGI:MGI:1096347 | Sema3f | PMID:22790009|MGI:MGI:5437554 | GO:1902285 | semaphorin-plexin signaling pathway involved in neuron projection guidance | IMP | PANTHER:PTHR11036 | 20130723 | NCBITaxon:10090 | |||||||||||||||
79 | Changed | RLovering | BHF-UCL | MGI:MGI:1100492 | Nrp2 | PMID:22790009|MGI:MGI:5437554 | GO:1902285 | semaphorin-plexin signaling pathway involved in neuron projection guidance | IMP | PANTHER:PTHR46806 | 20130723 | NCBITaxon:10090 | |||||||||||||||
80 | ontology revision required | Rlovering | BHF-UCL | UniProtKB:Q99959 | PKP2 | PMID:22889254 | GO:0086019 | cell-cell signaling involved in cardiac conduction | IMP | PANTHER:PTHR10372 | 20120928 | NCBITaxon:9606 | |||||||||||||||
81 | Changed | RLovering | BHF-UCL | RNAcentral:URS00004C9052_9606 | URS00004C9052_9606 | PMID:23069713 | GO:1905283 | negative regulation of epidermal growth factor receptor signaling pathway involved in heart process | IDA | 20160929 | GO:0035051|CL:0000134 | NCBITaxon:9606 | |||||||||||||||
82 | Changed | RLovering | BHF-UCL | MGI:MGI:102709 | Cav1 | PMID:25017399|MGI:MGI:5607357 | GO:0086098 | angiotensin-activated signaling pathway involved in heart process | IGI | UniProtKB:P09470 | PANTHER:PTHR10844 | 20141107 | NCBITaxon:10090 | ||||||||||||||
83 | Changed | RLovering | BHF-UCL | MGI:MGI:98397 | Src | PMID:25017399|MGI:MGI:5607357 | GO:0086098 | angiotensin-activated signaling pathway involved in heart process | IGI | UniProtKB:P09470|UniProtKB:P49817 | PANTHER:PTHR24418 | 20141107 | NCBITaxon:10090 | ||||||||||||||
84 | ontology revision required | Rlovering | BHF-UCL | ZFIN:ZDB-GENE-080227-9 | rnf207b | PMID:25281747|ZFIN:ZDB-PUB-141005-1 | GO:0086019 | cell-cell signaling involved in cardiac conduction | IMP | PANTHER:PTHR22635 | 20150227 | NCBITaxon:7955 | |||||||||||||||
85 | Changed | RLovering | BHF-UCL | MGI:MGI:1274781 | Robo1 | PMID:25691540|MGI:MGI:5913048 | GO:0035481 | positive regulation of Notch signaling pathway involved in heart induction | IDA | PANTHER:PTHR12231 | 20180514 | EMAPA:16346 | NCBITaxon:10090 | ||||||||||||||
86 | Changed | RLovering | BHF-UCL | MGI:MGI:1890110 | Robo2 | PMID:25691540|MGI:MGI:5913048 | GO:0035481 | positive regulation of Notch signaling pathway involved in heart induction | IDA | PANTHER:PTHR12231 | 20180514 | EMAPA:16346 | NCBITaxon:10090 | ||||||||||||||
87 | Changed | RLovering | BHF-UCL | UniProtKB:Q13253 | NOG | PMID:8582276 | GO:0060825 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation | IMP | PANTHER:PTHR10494 | 20110118 | NCBITaxon:9606 | |||||||||||||||
88 | Changed | RLovering | BHF-UCL | UniProtKB:Q13253 | NOG | PMID:8582276 | GO:2000313 | regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation | IMP | PANTHER:PTHR10494 | 20110707 | NCBITaxon:9606 | |||||||||||||||
89 | Changed | RLovering | BHF-UCL | Xenbase:XB-GENE-487006 | fgf2.L | PMID:8582276 | GO:0060825 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation | IDA | 20110118 | NCBITaxon:8355 | ||||||||||||||||
90 | Changed | dsiegele | CACAO | MGI:MGI:108075 | Smo | PMID:21209331|MGI:MGI:4888042 | GO:0021910 | smoothened signaling pathway involved in ventral spinal cord patterning | IMP | PANTHER:PTHR11309 | 20111116 | NCBITaxon:10090 | |||||||||||||||
91 | Only 1 copy of this annotation in Protein2GO | Changed | dsiegele | CACAO | AGI_LocusCode:AT3G09770 | LOG2 | PMID:23696092|TAIR:Publication:501755020 | GO:1901527 | abscisic acid-activated signaling pathway involved in stomatal movement | IMP | TAIR:locus:2075069 | 20160611 | NCBITaxon:3702 | ||||||||||||||
92 | Changed | dsiegele | CACAO | AGI_LocusCode:AT3G09770 | LOG2 | PMID:23696092|TAIR:Publication:501755020 | GO:1901527 | abscisic acid-activated signaling pathway involved in stomatal movement | IMP | TAIR:locus:2075069 | 20210331 | NCBITaxon:3702 | |||||||||||||||
93 | Changed | jlewsmith | CGD | CGD:CAL0000199031 | SST2 | PMID:16400182|CGD_REF:CAL0115369 | GO:0000754 | adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion | IMP | PANTHER:PTHR10845 | 20140625 | NCBITaxon:237561 | |||||||||||||||
94 | Changed | hattrill | FlyBase | FB:FBgn0284084 | wg | PMID:11076769|FB:FBrf0131347 | GO:0061316 | canonical Wnt signaling pathway involved in heart development | IMP | PANTHER:PTHR12027 | 20180112 | NCBITaxon:7227 | |||||||||||||||
95 | Changed | hattrill | FlyBase | FB:FBgn0004514 | Oct-TyrR | PMID:12535676|FB:FBrf0155846 | GO:0010578 | regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway | IDA | PANTHER:PTHR24248 | 20130425 | NCBITaxon:7227 | |||||||||||||||
96 | Changed | hattrill | FlyBase | FB:FBgn0010333 | Rac1 | PMID:16061696|FB:FBrf0200340 | GO:0002433 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis | IDA | PANTHER:PTHR24072 | 20071204 | NCBITaxon:7227 | |||||||||||||||
97 | Changed | hattrill | FlyBase | FB:FBgn0014011 | Rac2 | PMID:16061696|FB:FBrf0200340 | GO:0002433 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis | IDA | PANTHER:PTHR24072 | 20071204 | NCBITaxon:7227 | |||||||||||||||
98 | Changed | hattrill | FlyBase | FB:FBgn0015924 | crq | PMID:16061696|FB:FBrf0200340 | GO:0002433 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis | IDA | PANTHER:PTHR11923 | 20071204 | NCBITaxon:7227 | |||||||||||||||
99 | Changed | hattrill | FlyBase | FB:FBgn0034540 | Lrt | PMID:19793885|FB:FBrf0209122 | GO:2001283 | Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell | IGI | FB:FBgn0005631 | 20120126 | NCBITaxon:7227 | |||||||||||||||
100 | Changed | hattrill | FlyBase | UniProtKB:Q8T6S7 | plexA | PMID:20826677 | GO:2000305 | semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance | IGI | FB:FBgn0011259 | 20110324 | NCBITaxon:7240 |