National EML information re BPG

	A	B	C	D	E	F	G	H
1	Global Mapping of Benzathine Penicillin G \| RhEACH for RHD Action \| Confidential
2	Country	National Medicines List/ Formulary / Standard Treatment Guidelines	Benzathine benzylpenicillin (details)			Comments - including year of guidelines, children's EML, any other notation in EML	Any details about BPG in country - including source of product, reported problems and details of correspondent
3			0.6 million IU	1.2 million IU	2.4 million IU

4	WHO - Model List of Medicines	http://www.who.int/selection_medicines/committees/expert/20/EML_2015_FINAL_amended_AUG2015.pdf?ua=1	Not mentioned	Powder for injection: 900 mg benzylpenicillin (= 1.2 million IU) in 5‐ mL vial	1.44 g benzylpenicillin (= 2.4 million IU) in 5‐ mL vial.	19th List Amended Aug 2015
5	Afghanistan	http://www.who.int/selection_medicines/country_lists/afg/en/		Penicillin Benzyl Benzathine 1.2MU per vial, powder for injection ampoule-vial	Penicillin Benzyl Benzathine 2.4MU per vial,powder for injection ampoule-vial	2007
6	Albania			Benzathine Benzylpenicilline 1.2 million IUhttp://apps.who.int/medicinedocs/documents/s19549sq/s19549sq.pdf 2011		2011
7	Algeria	http://www.who.int/selection_medicines/country_lists/dza/en/ http://www.who.int/selection_medicines/country_lists/dza_2006.pdf?ua=1	BENZATHINE BENZYL PENICILLINE powder for injection	BENZATHINE BENZYL PENICILLINEPowder for injection		2006
8	Andorra
9	Angola	http://www.who.int/selection_medicines/country_lists/ago/en/			Penicilina Benzatinica vial injection	2008
10	Antigua and Barbuda					Does not have EML. Informal EML exists which is a mixture of the OECS/PPS formulary, found in the MBS Ref: https://issuu.com/abtworker/docs/ab_healthsystemprivatesectorassess_fin/85 (page 59)
11	Argentina	http://www.who.int/selection_medicines/country_lists/arg/en/		Benzathine benzylpenicillin		2005
12	Armenia	http://www.who.int/selection_medicines/country_lists/arm/en/
13	Australia	http://www.rhdaustralia.org.au/sites/default/files/resources/guideline_0_0.pdf	450mg (0.6 million U) <20kg single dose of BPG, im treatment for streptococcal infection	900mg (1.2 million U) >20kg single dose of BPG, im treatment for streptococcal infection		2012	Secondary prophylaxis in pregnancy: 900 mg (1,200,000 U) ≥20 kg 450 mg (600,000 U) < 20 kg Deep im injection 4 weekly, or 3 weekly for selected groups* ARF Treatment: single injection of intramuscular BPG (1,200,000 U or 600,000 U, if less than 20 kg) or a 10-day course of oral penicillin V (250 mg twice daily in children, 500 mg twice daily in adolescents and adults).
14	Austria
15	Azerbaijan
16	Bahamas
17	Bahrain	http://apps.who.int/medicinedocs/documents/s19536en/s19536en.pdf?ua=1		Note: 900 mg of Benzathine penicillin = 720 mg of Benzylpenicillin (1.2 million units) approximately. � Penadur Injection 1,200,000 IU.		Drug formulary 2009
18	Bangladesh	http://www.who.int/selection_medicines/country_lists/bgd_eml_2008.pdf?ua=1		Benzathine benzylpenicillin (Powder for injection)		List of essential drugs 2008
19	Barbados	http://apps.who.int/medicinedocs/documents/s18839en/s18839en.pdf		PENICILLIN G BENZATHINE Indications: Streptococcal infections, neisseria meningitidis, clostridium tetani, corynebacterium diphtheriae, treponema pallidum, listeria monocytogenes. Caution/Side Effects: History of allergy, hypersensitivity. Urticaria, joint pains, fever, angioneurotic odema. Anaphylactic shock, hemolytic anemia, exfoliative dermatitis. Dose: 300,000-1.2 million units/day divided every 3-4 hours. Preparations: 2.4mu Injection Penicillin G Benzathine (PDN\PHA); 1.301 per Vial Unicil L-A (UNP\COL); 1.6400 per Vial		Barbados National Drug Formulary (BNDF). A Guide to Rational Prescribing. Thirtieth Edition, 2011-2012
20	Belarus
21	Belgium
22	Belize	http://www.who.int/selection_medicines/country_lists/blz_formulary_2009_11.pdf?ua=1		Benzylpenicillin powder for injection, 600 mg (= 1 million IU), 3 g (= 5 million IU) (sodium or potassium salt) in vial		Belize Drug Formulary and Therapeutics Manual, Ninth Edition, 2009 - 2011
23	Benin
24	Bhutan	http://apps.who.int/medicinedocs/documents/s19471en/s19471en.pdf?ua=1		Benzathine Benzylpenicillin 24 lakh unit inj		National Essential Drug List (2012)
25	Bolivia	http://apps.who.int/medicinedocs/documents/s18843es/s18843es.pdf?ua=1		Bencilpenicilina benzatínica 1.200.000 UI Inyectable J01CE08 Bencilpenicilina benzatínica 2.400.000 UI Inyectable J01CE08 Bencilpenicilina procaínica 400.000 UI Inyectable J01CE09		Listado Nacional de Medicamentos Esenciales LINAME 2011-2013 - Bolivia
26	Bosnia and Herzegovina
27	Botswana	http://apps.who.int/medicinedocs/documents/s19479en/s19479en.pdf?ua=1		Benzathine penicillin 2.4MU pwd injection Benzyl penicillin (Penicillin G) 0.6g (1MU) injection Benzyl penicillin (Penicillin G) 3g (5MU) injection		Botswana Essential Drug List (BEDL), 2nd edition, 2012
28	Brazil	http://www.who.int/selection_medicines/country_lists/Brazil_rename2010.pdf?ua=1		benzilpenicilina benzatina pó para suspensão injetável 600.000 UI e 1.200.000 UI		Relação Nacional de Medicamentos Essenciais 2010
29	Brunei Darussalam
30	Bulgaria	http://www.mh.government.bg/bg/ministerstvo/komisii/savet-po-tseni-i-reimbursirane-na-lekarstvenite-produkti/				2009 (Document in Bulgarian)
31	Burkina Faso	http://www.remed.org/html/politique_pharmaceutique_burki.html		Benzathine Benzylpénicilline Poudre Injectable 1,2 et 2,4 MUI		Liste Nationale des Médicaments Essentiels sous Dénomination Commune Internationale (2007)
32	Burundi	http://www.who.int/selection_medicines/country_lists/Burundi_LNME_2012.pdf?ua=1		Benzathine benzylpeniclliine, flacon, 2,4M U (page 73)		Liste de médicaments essentiels (2012)
33	Cabo Verde
34	Cambodia	http://www.who.int/selection_medicines/country_lists/khm_essentialdrugs_2003.pdf?ua=1		NO RECORDS OF BPG IN EML		Essential Drugs (2003)
35	Cameroon	http://www.who.int/selection_medicines/country_lists/cmr/en/		Benzathine benzl peniclline Injection 1,2 MUI Benzyl Penicilline Injection 1MUI		Liste nationale des médicaments essentiels (2009)
36	Canada
37	Central African Republic	http://www.who.int/selection_medicines/country_lists/caf_eml_2009.pdf?ua=1		BENZATHINE BENZYL PENICILLINE sol inj		Liste nationale des médicaments essentiels en République centrafricaine (2009).		BENZATHINE PENICILLINE (Extencilline® 1,2 millions), en une injection. Full details re indication for RF p.81
38	Chad
39	Chile
40	China	http://apps.who.int/medicinedocs/documents/s18851en/s18851en.pdf		benzathine benzylpenicillin - Not on the National EML, however on the provincial EMLs for the following provinces (JS,FJ,HUB,GD)		Comparative Analyses of China National &Twentytwo selected Provincial Essential Medicine Lists to the WHO 2011 Model List	Further details to follow
41	Colombia	http://apps.who.int/medicinedocs/documents/s18382es/s18382es.pdf?ua=1		NOT IN EML		Listado de Medicamentos Vitales no Disponibles. Actualizado a febrero de 2011 - Colombia
42	Comoros
43	Congo
44	Costa Rica
45	Côte d'Ivoire
46	Croatia	http://www.who.int/selection_medicines/country_lists/hrv_2010.pdf?ua=1		benzatinbenzil-penicilin		Date not found
47	Cuba
48	Cyprus
49	Czech Republic
50	Democratic People's Republic of Korea (North Korea)	http://www.who.int/selection_medicines/country_lists/prk_eml.pdf?ua=1		benzathine benzylpenicillin 2.4 million IU		powder for injection, 1.44 g benzylpenicillin (= 2.4 million IU) in 5-ml vial. No date found
51	Democratic Republic of the Congo
52	Denmark
53	Djibouti	http://www.who.int/selection_medicines/country_lists/dji_Liste_2007.pdf?ua=1		benzathine benzylpenicillin 2.4 million IU		Injection 2007
54	Dominica
55	Dominican Republic	http://apps.who.int/medicinedocs/documents/s18241es/s18241es.pdf?ua=1		benzathine benzylpenicillin 2.4 million IU & Benzathine benzylpenicillin 1.4 million IU		benzathine benzylpenicillin 2.4 million IU (Use Level: Primary Care). Benzathine benzylpenicillin 1.4 million IU (Use Level: Specialized care). 2005
56	Ecuador	http://www.who.int/selection_medicines/country_lists/ecu_cuadro_general.pdf?ua=1		benzathine benzylpenicillin 2.4 million IU & Benzathine benzylpenicillin 1.4 million IU		Use: Parenteral 2009
57	Egypt	http://www.who.int/selection_medicines/country_lists/EGY_EML_2006.pdf?ua=1		benzathine benzylpenicillin 1.2 million IU		Injection. For use by all medical professionals. 2006
58	El Salvador	http://www.who.int/selection_medicines/country_lists/SLV_Lista_2010.pdf?ua=1		benzathine benzylpenicillin 1.2 million IU		Powder for suspension for injection I.M. Bottle vial with or without thinner. 2009
59	Equatorial Guinea
60	Eritrea	http://www.who.int/selection_medicines/country_lists/eri_eml_2010.pdf?ua=1		benzathine benzylpenicillin 2.4 million IU & Benzathine benzylpenicillin 1.4 million IU		powder for injection, 1.44g in 5ml vial (2.4 million IU) 720mg in 5ml vial (1.2million IU). 2010
61	Estonia
62	Ethiopia	http://www.who.int/selection_medicines/country_lists/Ethiopia_2010.pdf?ua=1		benzathine benzylpenicillin 2.4 million IU & Benzathine benzylpenicillin 1.4 million IU		Injection, 0.6, 1.2, 2.4, MIU in via. 2010
63	Fiji	http://www.who.int/selection_medicines/country_lists/fji_formulary_2006.pdf?ua=1			benzathine benzylpenicillin 2.4 million IU	Divisional + Specialist + Sub divisional hospitals + Health Centres. 2006
64	Finland	http://www.who.int/selection_medicines/country_lists/fji_pharmacological_list.pdf?ua=1		benzathine benzylpenicillin 2.4 million IU		Injection. Date not found.
65	France
66	Gabon	http://www.remed.org/html/politique_pharmaceutique_gabon.html		benzathine benzylpenicillin 2.4 million IU
67	Gambia
68	Georgia	http://apps.who.int/medicinedocs/documents/s19025en/s19025en.pdf?ua=1		benzathine benzylpenicillin 2.4 million IU		-powder for injection: 1.44 g benzylpenicillin (= 2.4 million IU)in 5-ml vial. 2007
69	Germany
70	Ghana	http://www.who.int/selection_medicines/country_lists/gha2004.pdf?ua=1		benzathine benzylpenicillin 1.2 million IU		Level of Care: Health Centre without Doctor. Injection, 1.2 MU. 2007
71	Greece
72	Grenada
73	Guatemala
74	Guinea	http://www.who.int/selection_medicines/country_lists/GuineeConakry_STG_2013.pdf?ua=1		benzathine benzylpenicillin 2.4 million IU		Injection in IM in a single dose and cotrimoxazole 480 mg, 2CP x 2/day for 7 days if allergy to penicillin, give only Erythromycin 500 mg due to 2CP x 2 /day for 7 days. 2013
75	Guinea-Bissau
76	Guyana	http://www.who.int/selection_medicines/country_lists/GUYANA_EDL_2009_10.pdf?ua=1		benzathine benzylpenicillin 1.2 million IU		2010
77	Haiti	http://www.who.int/selection_medicines/country_lists/Haiti_LNME_2012.pdf?ua=1		benzathine benzylpenicillin 2.4 million IU & Benzathine benzylpenicillin 1.4 million IU		2012
78	Honduras	http://apps.who.int/medicinedocs/documents/s18372es/s18372es.pdf?ua=1		benzathine benzylpenicillin 1.2 million IU		2011
79	Hungary
80	Iceland
81	India	http://www.who.int/selection_medicines/country_lists/ind/en/		Benzathine benzylpenicillin 1.4 million IU Powder for injection: 900 mg benzylpenicillin (=1.2 million IU) in 5 ml vial 2011	benzathine benzylpenicillin 2.4 million IU Powder for injection: 1.44 g benzylpenicillin (=2.4 million IU) in 5 ml vial. 2011	Longacillin (Max retail price): - Benzathine Benzylpenicillin powder for injection (Manufacturer - HAL) Packing: 0.6 (7.69 INR), 1.2 (12.04 INR) & 2.4 (18.29 INR) million IU Pencom - Benzathine Benzylpenicillin powder for injection (Manufacturer - Alembic) Packing (Max retail price): 0.6 (7.32 INR) & 1.2 (10.76 INR) million IU Pencom-La- Benzathine Benzylpenicillin powder for injection (Manufacturer - Alembic) Packing (Max retail price): : 1.2 (12.58 INR) & 2.4 million IU (16.24 INR) Pencom-La12- Benzathine Penicillin G powder for injection (Manufacturer - Wyeth) Packing (Max retail price): : 1.2 million IU (12.13 INR). Indications: Prophylactic in rheumatic fever. Pencom-La24- Benzathine Penicillin G powder for injection (Manufacturer - Wyeth) Packing (Max retail price): 2.4 million IU (18.3 INR). Indications: Syphilis. Pencom-La6- Benzathine Penicillin G powder for injection (Manufacturer - Wyeth) Packing (Max retail price): 0.6 million IU (8.24 INR). Indications: Streptococcal infections, sore throat, pyoderma. URTI: ADULTS:(All dose in units) Single inj of 12 L. OLDER CHILDREN: Single inj of 9 L. INFANTS & CHILDREN BELOW 27KGS: 3-6 L. Syphilis (primary, secondary & latent): 24 L (1dose). Late (tertiary and neurosyphilis): 24 L at 7 day intervals for 3 doses. CHILDREN BELOW 2YRS: 50,000units/kg/body wt. 2-12YRS: Adjust based on adult dosage shedule. Prophylaxis (rhematic fever & glomerulonephritis): After acute attack, a doses of 12 L once a month or 6 L every 2 weeks (by slow i.m).	Adult: IM Syphilis Early: 1.8 g as a single dose, usually as 2 inj in separate sites. Late: 1.8 g/wk for 3 consecutive wk. Treponemal infections 900 mg as a single dose. Streptococcal pharyngitis; Primary prevention of rheumatic fever 900 mg as a single dose. Prevent recurrence of acute rheumatic fever 900 mg 3-4 wkly. https://www.mimsonline.com/Myanmar/drug/search?q=Benzathine%20benzylpenicillin&AllFlag=ALL
82	Indonesia	http://www.who.int/selection_medicines/country_lists/idn_eml_2008.pdf?ua=1		benzathine benzylpenicillin 2.4 million IU & Benzathine benzylpenicillin 1.4 million IU		i.m. injection 1.2 millions IU/ml, box 25 vials @ 4 ml i.m. injection 2.4 millions IU/ml, box 25 vials @ 10 ml. 2008
83	Iran	http://www.who.int/selection_medicines/country_lists/irn_EDL_2009.pdf?ua=1		Penicillin G Benzathine 600,000 U		Parenteral. 2009
84	Iraq	http://apps.who.int/medicinedocs/documents/s17416e/s17416e.pdf?ua=1		benzathine benzylpenicillin 2.4 million IU & Benzathine benzylpenicillin 1.4 million IU		2010
85	Ireland
86	Israel
87	Italy
88	Jamaica	http://www.who.int/selection_medicines/country_lists/Jamaica_2008.PDF?ua=1			Benzathine Penicillin Inj. 2,400,000 Units	Indicated for "use for STDs" and in the "treatment of infections"	List of Vital Essential and Necessary Drugs and Medical Sundries for Public Health Institutions (2008)
89	Japan
90	Jordan	http://www.who.int/selection_medicines/country_lists/jor/en/	BENZATHINE PENICILLIN 600,000 IU INJ (unrestricted) in Jordan National Drug Formulary 2011	BENZATHINE PENICILLIN 1,200,000 IU INJ (unrestricted) in Jordan National Drug Formulary 2011		VIAL INJ BENZATHINE PENICILLIN VIAL 1,200,000 IU/VIAL (in Jordan EDL 2009)	BENZATHINE PENICILLIN VIAL 600,000 IU/VIAL (BENZADAR®) BENZATHINE PENICILLIN VIAL 1,200,000 IU/VIAL (BENZADAR®),( RETARPEN®) *in JRDL 2006
91	Kazakhstan
92	Kenya	http://apps.who.int/medicinedocs/documents/s18694en/s18694en.pdf			1.44g (2.4MU) in 5ml vial, powder form injection 2010	Level of use = 4 (out of 1-6) Theraputic Priority = Vital Procurement Priority = Core List: Routine items which should always be stocked and available.
93	Kiribati	http://www.who.int/selection_medicines/country_lists/kir_EDL_2009.pdf?ua=1			2.4MU, vial 2009	Medicinal drugs available at dispensary level, to be utilised by registered nursing officer. RHD and RF common in Kiribati. If the rheumatic fever did not involve the heart: Benzathine penicillin 1.2 megaunits every 4 weeks for 5 years or up to 18years of age. OR• Penicillin V 250 mg orally 12 hourly for the same duration (more difficult for patientcompliance) If the heart was involved the above prophylactic regimen is recommended until at least 40 years of age. Some sources recommend prophylaxis for life but there is no clear evidence base for this recommendation. 2007	Also recommended in 2013 Kirbati antibiotic guidelines http://www.wpro.who.int/southpacific/programmes/health_sector/pharmaceuticals/KiribatiAntibioticGuidelines2013.pdf
94	Kuwait
95	Kyrgyzstan	http://www.who.int/selection_medicines/country_lists/Kyrg_2009.pdf?ua=1		Benzathini Benzypenicillin powder for injeciton 1.44g (2.4 ME)	Benzathini Benzypenicillin powder for injeciton 1.44g (2.4 ME)
96	Lao People's Democratic Republic (Laos)						http://fdd.gov.la/download/contents_documents/1411701061Laos%20summary%20report%20drug%20price_capability_component_English%20version.pdf
97	Latvia
98	Lebanon	http://www.who.int/hac/crises/lbn/sitreps/Lebanon_essential_medicine.pdf			Benzathine Benzylpenicillin 2.4 M IU for injection		Essential Medicines list 14th edition, March 2005: Used as antibacterial
99	Lesotho	http://www.who.int/selection_medicines/country_lists/lso_2005_STGs_EML.pdf?ua=1	For Secondary Prevention (prophylaxis until age 21) <30 kg: Benzathine Penicillin 600 000 units IM monthly 2005	For Secondary Prevention (prophylaxis until age 21) >30 kg: Benzathine Penicillin 1.2 million units IM monthly 2005		In cases of penicillin sensitivity: Ertythromycin 500mg 2 times daily. Early Syphilis: Benzathine penicillin G L.A. 2.4 IM 2005
100	Liberia