BioSci – Mid_Pharma
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Deal Size ($M)% of Deal SizeUpfront Cash ($M)% of UpfrontTotal Dev/RegIND FilingPh I StartPh II StartPh III StartPh III % of TotalFDA FilingFDA ApprovalFDA % of TotalEU FilingMajor EUJapan FilingJapan+
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All Mid AverageN=209$112.9430.6%$14.07245.7%$34.57$2.07$2.90$4.37$6.3918.5%$7.62$16.6648.2%$7.58$13.06$4.66$6.55
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Median$41.5044.5%$3.88476.0%$18.47$1.00$1.00$3.00$3.0016.2%$4.00$8.0043.3%$5.00$6.00$3.00$5.00
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Mid III AverageN=50$139.2027.8%$27.32141.8%$38.75$13.45$31.4881.2%$6.30$19.54$2.94$4.40
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Median$74.6028.2%$10.85193.5%$21.00$10.00$20.0095.2%$4.50$9.00$2.90$3.00
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Mid III AverageN=13$208.1323.2%$39.24123.2%$48.34$16.17$29.2360.5%$13.00$59.67$5.00$4.32
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2008+ Median$110.0036.4%$20.00200.0%$40.00$19.00$25.0062.5%$13.00$19.00$5.00$2.00
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Mid III AverageN=19$150.0036.0%$33.60160.7%$53.99$17.45$52.5497.3%$4.08$12.02$3.13$5.07
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2004-07 Median$100.0030.5%$25.00122.0%$30.50$15.00$25.0082.0%$3.90$10.00$2.90$4.95
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Mid III AverageN=9$55.3325.2%$10.97126.9%$13.92$5.72$7.5454.2%$8.50$7.00$0.30$4.47
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2001-03 Median$19.0052.6%$5.00200.0%$10.00$3.50$5.5055.0%$8.50$7.00$0.30$3.00
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Mid III AverageN=9$100.6917.4%$7.17244.9%$17.56$10.17$16.4393.6%#DIV/0!$5.75#DIV/0!$0.50
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1998-00 Median$55.0027.3%$7.00214.3%$15.00$5.00$15.00100.0%#NUM!$5.75#NUM!$0.50
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Mid II AverageN=36$149.7925.1%$18.28205.6%$37.58$8.6022.9%$6.57$17.9147.7%$8.66$13.16$6.11$8.93
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Median$42.9054.8%$10.00235.0%$23.50$5.0021.3%$5.00$7.0029.8%$5.00$10.00$6.25$9.00
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Mid II AverageN=13$218.8323.5%$31.03165.6%$51.40$12.7824.9%$8.56$23.7546.2%$8.44$15.47$7.40$10.94
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2008+ Median$116.0030.2%$15.00233.3%$35.00$5.0014.3%$7.50$25.0071.4%$7.50$15.00$10.00$11.25
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Mid II AverageN=11$197.8823.2%$20.92219.9%$46.00$9.2720.2%$7.29$24.0052.2%$15.00$17.60$7.00$8.00
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2004-07 Median$100.0025.0%$10.00250.0%$25.00$5.0020.0%$8.00$7.0028.0%$15.00$12.00$7.00$8.00
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Mid II AverageN=6$15.6373.1%$2.47462.3%$11.42$2.3320.4%$2.60$5.8050.8%$2.00$2.00$2.00$3.50
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2001-03 Median$11.7578.7%$1.90486.8%$9.25$2.0021.6%$3.00$4.5048.6%$2.00$2.00$2.00$3.50
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Mid II AverageN=6$46.2239.7%$8.00229.1%$18.33$5.7531.4%$6.17$8.3345.4%$3.50$4.00$4.50$6.00
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1998-00 Median$38.1549.8%$7.00271.4%$19.00$4.5023.7%$7.00$7.0036.8%$3.50$4.00$4.50$5.00
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Mid I AverageN=13$75.6436.9%$6.94402.3%$27.92$6.00$5.1018.3%$5.50$11.0039.4%$3.80$6.91$4.68$6.84
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Median$32.0065.6%$4.25494.1%$21.00$7.00$4.0019.0%$5.00$9.0042.9%$3.40$5.00$3.75$5.00
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Mid Preclin AverageN=45$84.1140.6%$5.14664.2%$34.14$2.70$3.31$4.55$6.3118.5%$5.99$11.5033.7%$9.20$11.90$5.86$6.75
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Median$35.4039.5%$2.40583.3%$14.00$2.00$1.25$2.50$4.0028.6%$2.50$6.0042.9%$8.00$5.50$4.00$5.00
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Mid Preclin AverageN=13$177.5038.8%$8.40819.2%$68.81$4.75$5.22$7.05$8.5112.4%$11.10$22.0632.1%$10.50$19.73$10.75$8.87
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2008+ Median$190.0031.6%$6.60909.1%$60.00$4.00$3.50$5.25$6.5010.8%$11.90$21.6036.0%$10.50$18.00$5.00$10.00
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Mid Preclin AverageN=16$64.8343.6%$4.62611.7%$28.26$0.90$4.08$4.67$7.1825.4%$4.48$7.8327.7%$8.33$6.89$3.50$6.54
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2004-07 Median$20.7040.1%$1.50553.3%$8.30$0.68$1.15$3.00$3.2038.6%$2.00$5.0060.2%$8.00$5.00$3.50$4.50
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Mid Preclin AverageN=8$25.8741.7%$2.65407.5%$10.80$3.00$0.70$1.74$2.3922.1%$1.10$6.0255.7%#DIV/0!$4.00$4.00$3.83
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2001-03 Median$26.7537.4%$1.95512.8%$10.00$3.00$0.85$1.23$1.9019.0%$1.00$5.0050.0%#NUM!$4.00$4.00$5.00
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Mid Preclin AverageN=8$29.1644.4%$2.59499.6%$12.94$2.38$0.88$1.65$2.9222.6%$3.63$5.0438.9%#DIV/0!$0.25$1.75$2.40
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1998-00 Median$28.7541.7%$2.50480.0%$12.00$2.25$0.88$2.00$3.0025.0%$3.63$5.5045.8%#NUM!$0.25$1.75$2.40
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Mid Lead AverageN=22$79.9828.5%$7.96286.6%$22.81$0.73$3.42$3.03$4.8221.1%$5.05$7.7033.8%$6.00$7.23$1.00$4.06
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Median$21.1856.7%$1.25960.0%$12.00$0.75$1.00$2.25$3.2527.1%$2.00$2.5020.8%$5.00$4.50$1.00$2.00
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Mid Disc AverageN=43$109.8732.5%$8.54417.8%$35.68$2.18$2.26$4.21$5.5315.5%$6.13$12.7735.8%$9.48$14.04$3.16$7.20
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Median$35.0540.7%$2.50570.0%$14.25$1.50$1.00$3.00$3.0021.1%$3.00$5.0035.1%$5.00$8.00$2.50$4.00
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Mid Disc AverageN=9$315.6229.2%$21.20434.5%$92.11$3.47$7.50$7.55$13.4614.6%$15.83$38.1341.4%$13.13$24.67$4.53$12.70
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2008+ Median$237.2035.4%$6.501293.1%$84.05$3.80$7.50$6.90$10.0011.9%$10.00$25.0029.7%$16.40$20.25$4.10$11.00
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Mid Disc AverageN=7$135.7236.8%$13.75363.3%$49.95$4.88$1.79$10.00$7.7915.6%$10.65$14.6429.3%$4.00$16.31$2.00$12.00
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2004-07 Median$56.2562.2%$6.50538.5%$35.00$2.00$1.00$10.00$5.0014.3%$7.50$10.0028.6%$4.00$9.63$2.00$12.00
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Mid Disc AverageN=16$44.5136.6%$3.29495.1%$16.29$1.51$0.88$2.21$2.6016.0%$4.64$5.6834.9%$4.00$4.00$2.00$2.50
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2001-03 Median$27.3041.9%$1.001143.0%$11.43$1.50$0.75$2.50$2.0017.5%$3.50$4.0035.0%$4.00$3.00$2.00$2.50
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Mid Disc AverageN=11$20.1442.9%$2.57336.2%$8.64$0.94$0.75$1.31$1.6519.1%$1.53$2.5028.9%#DIV/0!$2.75$2.25$2.63
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1998-00 Median$12.0070.8%$0.501700.0%$8.50$0.50$0.75$1.50$1.7520.6%$1.50$2.0023.5%#NUM!$2.75$2.25$3.00
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