EHC treatment- by-cohort data set.xlsx

	A	B	C	D	E	F	G	H	I	J	K	L	M	N	O	P	Q	R	S	T	U	V	W	X	Y	Z	AA	AB	AC	AD	AE	AF	AG	AH	AI	AJ	AK	AL	AM	AN	AO	AP	AQ	AR	AS	AT	AU	AV	AW	AX	AY	AZ	BA	BB	BC	BD
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2	* This table is last updated on 5 June, 2025. Please note that the information will be periodically reviewed and updated according to the latest changes in the treatment ladscape. The information for this table was provided by the EHC NMOs and the industry. The EHC also wishes to thank the EHC MAG members for their input. * Treatment-by-cohort table is for educational purposes only, does not endorse or promote any specific pharmaceutical organisation, drug or other medical intervention. It is developed, created, and delivered by the EHC independently from the industry. If you find any inaccuracies, please report them at education@ehc.eu.							In this table, EHC covers only the markets of its 49 members. EU countries are marked in green for convenience, they include: Austria, Belgium, Bulgaria, Croatia, Republic of Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia, Spain and Sweden.								treatment options marked in yellow were reported by the industry or indicated by EMA as licensed in the relevant EU countries but are not included in the treatment option lists provided by the EHC NMOs.
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7	Bleeding Disorder	Type of Product	Recombinant	Plasma- derived	SHL/EHL/UHL	Molecule	Brand name	License	Albania	Armenia	Austria	Azerbaijan	Belarus	Belgium	Bosnia and Herzegovina	Bulgaria	Croatia	Republic of Cyprus	Czech Republic	Denmark	Estonia	Finland	France	Georgia	Germany	Greece	Hungary	Iceland	Ireland	Israel	Italy	Kyrgyz Republic	Latvia	Lithuania	Luxembourg	Malta	North Macedonia	Moldova	Montenegro	the Netherlands	Norway	Poland	Portugal	Romania	Russia	Serbia	Slovakia	Slovenia	Spain	Sweden	Switzerland	Tajikistan	Turkey	Ukraine	UK	Uzbekistan
8	von Willebrand Disease (VWD)	VWF concentrate	x			vonicog alfa	Veyvondi/Vonvendi																		Veyvondi 650, 1300								Veyvondi 650, 1300
9				x		VWF	Wilfactin							Wilfactin 1000											Willfact 1000						Willfact
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11		VWF/FVIII concentrate		x		VWF/FVIII	Voncento	Licences in all EU countries			Voncento					Voncento	Voncento	Voncento	Voncento	Voncento	Voncento	Voncento	Voncento		Voncento 500/1200, 1000/2400	Voncento	Voncento		Voncento		Voncento		Voncento 250/600, 500/1200, 1000/2400	Voncento	Voncento	Voncento				Voncento		Voncento	Voncento	Voncento			Voncento	Voncento	Voncento	Voncento					Voncento
12		VWF/FVIII concentrate		x		VWF/FVIII	Haemate-P/Humate-P	Licences in all EU countries			Haemate-P		Haemate-P	Haemate 500/1200, 1000/2400		Haemate-P	Haemate-P 500/1200	Haemate-P	Haemate-P	Haemate-P	Haemate-P	Haemate-P			Haemate 250/600, 500/1200, 1000/2400	Haemate-P	Haemate-P				Haemate-P			Haemate-P	Haemate-P					Haemate-P	Haemate-P	Haemate-P	Haemate-P	Haemate-P			Haemate-P	Haemate-P	Haemate-P	Haemate-P
13				x		VWF/FVIII	Fanhdi/Alphanate																								Fanhdi and Alphanate
14				x		VWF/FVIII	Wilate						Wilate	Wilate 500/500, 1000/1000			Wilate 500/500								Wilate 500/500, 1000/1000						Wilate		Wilate 500/500, 1000/1000
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16				x		VWF/FVIII	Immunate/Immunate Stim Plus						Immunate				Immunate								Immunate Stim Plus - 500 I.E., 1000 I.E. : Nach Auflösen mit 5 ml (500 I.E. Packungsgröße) oder 10 ml (1000 I.E. Packungsgröße) sterilisiertem Wasser für Injektionszwecke enthält das Produkt 100 I.E./ml (500 I.E. und 1000 I.E. Packungsgröße) an Blutgerinnungsfaktor VIII vom Menschen und 60 I.E./ml (500 I.E. und 1000 I.E. Packungsgröße) an von-Willebrand-Faktor vom Menschen.								Immunate 500SV/375SV Immunate 1000SV/750SV
17		Desmopressin				Desmopressin	Octostim/Emosint/Minirin/Stimate							Desmopressine Ferring Cp 0,2mg Desmopressine Teva Cp 0,2mg Minirin amp 10ml i.v. 4 µg/ml Minirin spray nas 10 µg/dose Nocturna lyophilisat sub.ling. 25 µg 50µg			Minirin spray nas 5 ml (0,1 mg/mL) Minirin melt 120 mcg														Emosint and Minirin		Octostim 15mcg/ml
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19	Haemophilia A without inhibitors	FVIII concentrate	x		SHL	octocog alfa	Advate							Advate 250, 500, 1000, 1500, 2000, 3000			Advate 500, 1000								Advate 250, 500, 1000, 1500, 2000, 3000						Advate		Advate 250, 500, 1000
20			x		EHL	rurioctocog alfa pegol	Adynovi / Adynovate							Adynovi 500, 1000, 2000			Adynovi 500, 1000								Adynovi 250, 500, 1000, 2000						Adynovi		Adynovi 500, 1000, 2000
21			x		SHL	lonoctocog alfa	Afstyla	Licences in all EU countries			x			Afstyla 500, 1000, 2000		x	Afstyla 250, 500, 1000	x	x	x	x	x	x		Afstyla 250, 500, 1000, 1500, 2000, 3000	x	x		x		Afstyla		Afstyla 250, 500, 1000, 1500, 2000, 2500, 3000	x	x	x				x		x	x	x			x	x	x	x					x
22			x		EHL	efmoroctocog alfa	Elocta/Eloctate	All EU, UK, Switzerland, Russia, Turkey, Israel, Bosnia and Herzegovina, North Macedonia, Serbia			x			Elocta 250, 500, 750, 1000, 1500, 2000, 3000	x	x	Elocta 250, 500, 750, 1000, 1500, 2000, 3000	x	x	x	x	x	x		Elocta 250, 500, 750, 1000, 1500, 2000, 4000	x	x		x	x	Elocta		Elocta 250, 500, 750, 1000, 1500, 2000, 3000, 4000, 5000, 6000	x	x	x	x			x		x	x	x	x	x	x	x	x	x	x		x		x
23			x		EHL	turoctocog alfa pegol	Esperoct							Esperoct 500, 1000, 1500, 2000, 3000			Esperoct 500, 1000, 3000								Esperoct 500, 1000, 1500, 2000, 3000						Esperoct		Esperoct 500, 1000
24			x		EHL	damoctocog alfa pegol	Jivi	Licenced in all EU countries, B&H, Iceland, Norway, Switzerland, Turkey, UK			Jivi 500, 1000, 2000, 3000			Jivi 500, 1000, 2000, 3000	Jivi 2000, 3000	Jivi 500, 1000	Jivi 500, 1000, 2000, 3000	x	Jivi 500, 1000, 2000, 3000	Jivi 500, 1000, 2000, 3000	Jivi 500, 1000, 2000, 3000	Jivi 500, 1000, 2000, 3000	x		Jivi 500, 1000, 2000, 3000	Jivi 500, 1000, 2000	x	Jivi 500, 1000, 2000, 3000	x		Jivi 500, 1000, 2000, 3000		Jivi 250,1000, 2000, 3000	Jivi 500, 1000, 2000, 3000	Jivi 500, 1000, 2000, 3000	x				Jivi 500, 1000, 2000	Jivi 500, 1000, 2000, 3000	x	Jivi 1000, 2000	x			x	Jivi 500, 1000, 2000, 3000	Jivi 500, 1000, 2000, 3000	Jivi 500, 1000, 2000, 3000	Jivi 1000, 2000, 3000		x		x
25			x		SHL	octocog alfa	Kogenate FS												x														Kogenate 250, 500, 1000, 2000, 3000
26			x		SHL	octocog alfa	Kogenate Bayer/Helixate NexGen/Iblias
27			x		SHL	octocog alfa	Kovaltry	Licenced in all EU countries, UK, Switzerland, Norway, Israel, Iceland			Kovaltry 250, 500, 1000, 2000, 3000			Kovaltry 500, 1000, 2000, 3000		Kovaltry 500, 1000	x	Kovaltry 1000, 2000	Kovaltry 1000, 2000	Kovaltry 250, 500, 1000, 2000, 3000	x	Kovaltry 1000, 2000, 3000	Kovaltry 250, 500, 1000, 2000, 3000		Kovaltry 250, 500, 1000, 2000, 3000	Kovaltry 250, 1000, 2000, 3000	x	x	x	Kovaltry 1000, 2000	Kovaltry 250, 500, 1000, 2000, 3000		Kovaltry 250, 500, 1000, 2000, 3000	Kovaltry 500, 1000	Kovaltry 500, 1000, 2000, 3000	x				x	Kovaltry 250, 500, 1000, 2000, 3000	x	Kovaltry 500, 1000	Kovaltry 500, 100			x	x	Kovaltry 250, 500, 1000, 2000, 3000	Kovaltry 250, 500, 1000, 2000, 3000	Kovaltry 500, 1000, 2000				x
28			x		SHL	turoctocog alfa	Novoeight	Licenced in all EU countries			x			NovoEight 250, 500, 1000, 1500, 2000, 3000		x	NovoEight 250, 1000, 1500, 2000, 3000	x	x	x	x	x	x		NovoEight 250, 500, 1000, 1500, 3000	x	x		x		NovoEight		NovoEight 500, 1000	x	x	x				x		x	x	x			x	x	x	x
29			x		SHL	simoctocog alfa	Nuwiq/Vihuma						Nuwiq	Nuwiq 250, 500, 1000, 2000			Nuwiq 250, 500, 100, 2000								Nuwiq 250, 500, 1000, 2000, 3000, 4000 Vihuma 250, 500, 1000, 2000, 3000, 4000						Nuwiq		Nuwiq 250, 500, 1000, 2000 Vihuma 250, 500, 1000, 2000, 2500, 3000, 4000
30			x		SHL	moroctocog alfa	Refacto AF	Licenced in Albania, Austria, Belgium, Bosnia-Hersegovina, Bulgaria, Croatia, Cyprus, Czeck Republik, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Israel, Italy, Latvia, Lithuania, Luxembourg, North Macedonia, Malta, the Netherlands, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Turkey, Ukraine, United Kingdom and Uzbekistan	x		x			Refacto AF 250, 500, 1000, 2000, 3000	x	x	Refacto AF 250, 500, 1000, 2000	x	x	x	x	x	x		Refacto AF 250, 500, 1000, 2000, 3000	x	x	x	x	x	Refacto AF		Refacto AF 250, 500, 1000, 2000, 3000	x	x	x	x			x	x	x	x	x		x	x	x	x	x			x	x	x	x
31			x		SHL	octocog alfa	Recombinate																		Recombinate 1000
32				x			Octanate/Octanate kons/Octanate LV						Octanate	Octanate 250, 500, 1000			Octanate 500, 1000								Octanate 250, 500, 1000						Octanate		Octanate 500 SV, 1000 SV
33				x			Aafact
34				x			Amofil
35				x			Emoclot/Klott/Emowil						Emoclot				Emoclot 500, 1000														x
36				x			Beriate	DE, AT, IT, PT, ES, BG, HR, CZ, HU, PL, RO, SK, SI, EE, LV, LT, MT,			Beriate		Beriate			Beriate	Beriate		Beriate		Beriate				Beriate 250 IU, 500 IU, 1000 IU, 2000 IU		Beriate				Beriate		Beriate	Beriate		Beriate						Beriate	Beriate	Beriate			Beriate	Beriate	Beriate
37				x			Immunate/Immunate SD						Immunate				Immunate 500/375																Immunate 500SV/375SV Immunate 1000SV/750SV
38				x			Alphanate/Fanhdi																		Fanhdi 250 I.E., 500 I.E., 1000 I.E., 1500 I.E., 300 I.E. vWF, 600 I.E. vWF, 1200 I.E. vWF, 1800 I.E. vWF						Alphanate®/Fanhdi
39				x			Talate																								Talate
40				x			8Y
41				x			Factane
42				x			Haemoctin/Haemoctin Sdh																		Haemoctin 250, 500, 1000						Haemoctin
43				x			Humaclot/Humafactor-8
44				x			Koate DVI
45				x			Voncento							Haemate 500/1200, 1000/2400																	Haemate-P
46				x			Haemate-P/Humate-P/Haemate						Haemate-P
47				x			Wilate/Wilnativ						Wilate	Wilate 500/500, 1000/1000																	Wilate
48				x			Optivate/Optiwate																		Optivate 250 IU, 500 IU, 1000 IU, 430 IU vWF , 860 IU vWF , 1760 IU vWF
49				x			Octafil/Octafil LV
50				x			Faktor VIII SDH INTERSERO																		Faktor VIII 250,500, 1000
51			x		UHL	efanesoctocog alfa	Altuvoct	Licenced in all EU countries + UK, Israel, Switzerland			Altuvoct			Altuvoct		Altuvoct	Altuvoct	Altuvoct	Altuvoct	Altuvoct	Altuvoct	Altuvoct	Altuvoct		Altuvoct 250, 500, 1000, 2000, 3000, 4000	Altuvoct	Altuvoct		Altuvoct	Altuvoct	Altuvoct		Altuvoct	Altuvoct	Altuvoct	Altuvoct				Altuvoct		Altuvoct	Altuvoct	Altuvoct			Altuvoct	Altuvoct	Altuvoct	Altuvoct	Altuvoct				Altuvoct
52		FVIII mimetic/ Bispecific antibody				emicizumab	Hemlibra	Licenced in all EU countries (for severe), Georgia, Israel, Albania, Turkey, Serbia, Russia, Moldova, Belarus, Bosnia and Herzegovina, Azerbaijan, Kosovo, Kyrgyzstan	x (for severe)		x	x (for severe)	x (for children)	Hemlibra 30mg/ml Hemlibra 60mg/0,4ml Hemlibra 105mg/0,7ml Hemlibra 150mg/ml	x (for severe)	x	Hemlibra 30mg/ml Hemlibra 60mg/0,4ml Hemlibra 105mg/0,7ml Hemlibra 150mg/ml	x	x	x	x	x	x	x (for severe)	Hemlibra 30mg/ml Hemlibra 60mg/0,4ml Hemlibra 105mg/0,7ml Hemlibra 150mg/ml	x	x		x	x (for severe, moderate and mild)	x	x (for severe and moderate)	Hemlibra 30mg/ml Hemlibra 60mg/0,4ml Hemlibra 105mg/0,7ml Hemlibra 150mg/ml	x	x	x		x (severe and moderate)		x		x	x	x	x (severe and moderate)	x (for severe)	x	x	x	x			x (for severe)
53		anti-tissue factor pathway inhibitor (anti-TFPI)				marstacimab	HYMPAVZI	Licenced in all EU countries + Iceland and Norway. Ofiicially commercialised in Germany.			HYMPAVZI			HYMPAVZI		HYMPAVZI	HYMPAVZI	HYMPAVZI	HYMPAVZI	HYMPAVZI	HYMPAVZI	HYMPAVZI	HYMPAVZI		HYMPAVZI	HYMPAVZI	HYMPAVZI	HYMPAVZI	HYMPAVZI		HYMPAVZI		HYMPAVZI	HYMPAVZI	HYMPAVZI	HYMPAVZI				HYMPAVZI	HYMPAVZI	HYMPAVZI	HYMPAVZI	HYMPAVZI			HYMPAVZI	HYMPAVZI	HYMPAVZI	HYMPAVZI
54		Gene Therapy				valoctogene roxaparvovec	Roctavian Valoctocogene roxaparvovec BMN-270	Italy, Germany																	Roctavian						Roctavian		Roctavian 2 x 10¹³ vg/mL
55		Desmopressin					Octostim/Emosint/Minirin																								Emosint and Minirin
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57	Haemophilia A with Inhibitors	Bypassing agent	x			eptacog beta	Cevenfacta												x						Cevenfacta 1 mg, 2 mg, 5 mg						Cevenfacta		Cevenfacta 1mg, 2mg, 5mg
58			x			eptacog alfa	NovoSeven / NovoSeven RT/Coagil-VII						NovoSeven/ Coagil-VII	NovoSeven 1mg, 2mg, 5 mg indispo -> 2026			NovoSeven 1mg, 2mg, 5 mg								NovoSeven 1mg, 2mg, 5 mg, 8 mg						NovoSeven		NovoSeven 1mg (50KSV), 2mg (100KSV)
59				x		activated prothrombin complex concentrate (APPC)	FEIBA						FEIBA	FEIBA 1000			FEIBA 500								FEIBA 500, 1000						FEIBA		FEIBA 500V, 1000V
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61		FVIII mimetic/ Bispecific antibody				emicizumab	Hemlibra	Licenced in all EU countries, Norway, Iceland, Georgia, Moldova, Ukraine, Russia, Albania, Israel, North Macedonia, Bosnia and Herzegovina, Serbia, Montenegro, Turkey,Azerbaijan, Belarus, Kyrgyzstan	x		x	x	x (for children)	Hemlibra 30mg/ml Hemlibra 60mg/0,4ml Hemlibra 105mg/0,7ml Hemlibra 150mg/ml	x	x	Hemlibra 30mg/ml Hemlibra 60mg/0,4ml Hemlibra 105mg/0,7ml Hemlibra 150mg/ml	x	x	x	x	x	x	x	Hemlibra 30mg/ml Hemlibra 60mg/0,4ml Hemlibra 105mg/0,7ml Hemlibra 150mg/ml	x	x	x	x	x	Hemlibra	x	Hemlibra 30mg/ml Hemlibra 60mg/0,4ml Hemlibra 105mg/0,7ml Hemlibra 150mg/ml	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x			Hemlibra 30mg/ml Hemlibra 150mg/ml	x
62		anti-tissue factor pathway inhibitor (anti-TFPI)				concizumab	Alhemo	Licenced in all EU countries																	Alhemo
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64	Acquired Haemophlia A (AHA)*	Bypassing agents		x		activated prothrombin complex concentrate (APPC)	FEIBA
65			x			rFVIIa (eptacog alfa)	NovoSeven
66		Porcine FVIII Concentrate	x		SHL	rpFVIII (susoctocog alfa)	Obizur (in adults)																		Obizur 500						Obizur
67		Human FVIII Concentrates (only in cases of low inhibitor titer <5 BU and if bypassing agents are not available)		x		FVIII concentrate	Octanate/Octanate kons/Octanate LV						Octanate	Octanate 250, 500, 1000			Octanate 500, 1000								Octanate 250, 500, 1000						Octanate		Octanate 500 SV, 1000 SV
68				x			Aafact
69				x			Amofil
70				x			Emoclot/Klott/Emowil						Emoclot				Emoclot 500, 1000														x
71				x			Beriate	DE, AT, IT, PT, ES, BG, HR, CZ, HU, PL, RO, SK, SI, EE, LV, LT, MT,			Beriate		Beriate			Beriate	Beriate		Beriate		Beriate				Beriate 250 IU, 500 IU, 1000 IU, 2000 IU		Beriate				Beriate		Beriate	Beriate		Beriate						Beriate	Beriate	Beriate			Beriate	Beriate	Beriate
72				x			Immunate/Immunate SD						Immunate				Immunate 500/375																Immunate 500SV/375SV Immunate 1000SV/750SV
73				x			Alphanate/Fanhdi																		Fanhdi 250 I.E., 500 I.E., 1000 I.E., 1500 I.E., 300 I.E. vWF, 600 I.E. vWF, 1200 I.E. vWF, 1800 I.E. vWF						Alphanate®/Fanhdi
74				x			Talate																								Talate
75				x			8Y
76				x			Factane							Factane 1000, 2000
77				x			Haemoctin/Haemoctin Sdh																		Haemoctin 250, 500, 1000						Haemoctin
78				x			Humaclot/Humafactor-8
79				x			Koate DVI
80				x			Voncento							Haemate 500/1200, 1000/2400																	Haemate-P
81				x			Haemate-P/Humate-P/Haemate						Haemate-P
82				x			Wilate/Wilnativ						Wilate	Wilate 500/500, 1000/1000																	Wilate
83				x			Optivate/Optiwate																		Optivate 250 IU, 500 IU, 1000 IU, 430 IU vWF , 860 IU vWF , 1760 IU vWF
84				x			Octafil/Octafil LV
85				x			Faktor VIII SDH INTERSERO																		Faktor VIII 250,500, 1000
86			x		SHL	octocog alfa	Advate							Advate 250, 500, 1000, 1500, 2000, 3000			Advate 500, 1000								Advate 250, 500, 1000, 1500, 2000, 3000						Advate		Advate 250, 500, 1000
87			x		EHL	rurioctocog alfa pegol	Adynovi / Adynovate							Adynovi 500, 1000, 2000			Adynovi 500, 1000								Adynovi 250, 500, 1000, 2000						Adynovi		Adynovi 500, 1000, 2000
88			x		SHL	lonoctocog alfa	Afstyla	Licences in all EU countries			x			Afstyla 500, 1000, 2000		x	Afstyla 250, 500, 1000	x	x	x	x	x	x		Afstyla 250, 500, 1000, 1500, 2000, 3000	x	x		x		Afstyla		Afstyla 250, 500, 1000, 1500, 2000, 2500, 3000	x	x	x				x		x	x	x			x	x	x	x					x
89			x		EHL	efmoroctocog alfa	Elocta/Eloctate	All EU, UK, Switzerland, Russia, Turkey, Israel, Bosnia and Herzegovina, North Macedonia, Serbia			x			Elocta 250, 500, 750, 1000, 1500, 2000, 3000	x	x	Elocta 250, 500, 750, 1000, 1500, 2000, 3000	x	x	x	x	x	x		Elocta 250, 500, 750, 1000, 1500, 2000, 4000	x	x		x	x	Elocta		Elocta 250, 500, 750, 1000, 1500, 2000, 3000, 4000, 5000, 6000	x	x	x	x			x		x	x	x	x	x	x	x	x	x	x		x		x
90			x		EHL	turoctocog alfa pegol	Esperoct							Esperoct 500, 1000, 1500, 2000, 3000			Esperoct 500, 1000, 3000								Esperoct 500, 1000, 1500, 2000, 3000						Esperoct		Esperoct 500, 1000
91			x		EHL	damoctocog alfa pegol	Jivi	Licenced in all EU countries			x			Jivi 1000, 2000, 3000		x	Jivi 500, 1000, 2000, 3000	x	x	x	x	x	x		Jivi 250, 500, 1000, 2000, 3000	x	x		x		Jivi		Jivi 250, 500, 1000, 2000, 3000	x	x	x				x		x	x	x			x	x	x	x
92			x		SHL	octocog alfa	Kogenate FS												x														Kogenate 250, 500, 1000, 2000, 3000
93			x		SHL	octocog alfa	Kogenate Bayer/Helixate NexGen/Iblias
94			x		SHL	octocog alfa	Kovaltry	Licenced in all EU countries			x			Kovaltry 500, 1000, 2000, 3000		x	x	x	x	x	x	x	x		Kovaltry 250, 500, 1000, 3000	x	x		x		Kovaltry		Kovaltry 250, 500, 1000, 2000, 3000	x	x	x				x		x	x	x			x	x	x	x
95			x		SHL	turoctocog alfa	Novoeight	Licenced in all EU countries			x			NovoEight 250, 500, 1000, 1500, 2000, 3000		x	NovoEight 250, 1000, 1500, 2000, 3000	x	x	x	x	x	x		NovoEight 250, 500, 1000, 1500, 3000	x	x		x		NovoEight		NovoEight 500, 1000	x	x	x				x		x	x	x			x	x	x	x
96			x		SHL	simoctocog alfa	Nuwiq/Vihuma						Nuwiq	Nuwiq 250, 500, 1000, 2000			Nuwiq 250, 500, 100, 2000								Nuwiq 250, 500, 1000, 2000, 3000, 4000 Vihuma 250, 500, 1000, 2000, 3000, 4000						Nuwiq		Nuwiq 250, 500, 1000, 2000 Vihuma 250, 500, 1000, 2000, 2500, 3000, 4000
97			x		SHL	moroctocog alfa	Refacto AF	Licenced in Albania, Austria, Belgium, Bosnia-Hersegovina, Bulgaria, Croatia, Cyprus, Czeck Republik, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Israel, Italy, Latvia, Lithuania, Luxembourg, North Macedonia, Malta, the Netherlands, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Turkey, Ukraine, United Kingdom and Uzbekistan	x		x			Refacto AF 250, 500, 1000, 2000, 3000	x	x	Refacto AF 250, 500, 1000, 2000	x	x	x	x	x	x		Refacto AF 250, 500, 1000, 2000, 3000	x	x	x	x	x	Refacto AF		Refacto AF 250, 500, 1000, 2000, 3000	x	x	x	x			x	x	x	x	x		x	x	x	x	x			x	x	x	x
98			x		SHL	octocog alfa	Recombinate																		Recombinate 1000
99		Desmopressin (only in cases of low inhibitor titer <5 BU and if bypassing agents are not available)				desmopressin	Octostim/Emosint/Minirin																								Emosint and Minirin
100		FVIII mimetic/ Bispecific antibody				emicizumab	Hemlibra	Licenced in all EU countries, Norway, Iceland, Georgia, Moldova, Ukraine, Russia, Albania, Israel, North Macedonia, Bosnia and Herzegovina, Serbia, Montenegro, Turkey,Azerbaijan, Belarus, Kyrgyzstan	x		x	x	x (for children)	Hemlibra 30mg/ml Hemlibra 60mg/0,4ml Hemlibra 105mg/0,7ml Hemlibra 150mg/ml	x	x	Hemlibra 30mg/ml Hemlibra 60mg/0,4ml Hemlibra 105mg/0,7ml Hemlibra 150mg/ml	x	x	x	x	x	x	x	Hemlibra 30mg/ml Hemlibra 60mg/0,4ml Hemlibra 105mg/0,7ml Hemlibra 150mg/ml	x	x	x	x	x	Hemlibra	x	Hemlibra 30mg/ml Hemlibra 60mg/0,4ml Hemlibra 105mg/0,7ml Hemlibra 150mg/ml	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x			Hemlibra 30mg/ml Hemlibra 150mg/ml	x