Ataxia Spreadsheet- Good

	A	B	C	D	E	F	G	H
1	Ataxia Type	Gene	When the gene was discovered	Genetic Testing	Key Symptoms (Main 3)	Estimated % of Genetic Ataxia Cases	Estimated Global Cases	Avg. Age Of Onset

2	ADCA Type 1 (CECBA)	CAMTA1	2000	Multi-Gene Panel	Ataxia, Mild Intellectual Disability, Behavioral Abnormalities	Rare	Rare	Early childhood
3	ADCA-DN	DNMT1	1994	Multi-Gene Panel	Cerebellar ataxia, Deafness, and Narcolepsy	Rare	Rare	30–40 years
4	AOA1	APTX	1996	Multi-Gene Panel	Ataxia, oculomotor apraxia, neuropathy	Rare	Few hundred–thousand	Mean: 4.3 years; Range: 2–10 years
5	AOA2	SETX	2004	Multi-Gene Panel	Tremor, neuropathy, cerebellar atrophy	Rare	Few hundred–thousand	Between 3 and 30 years
6	ARCA	Multiple	1990	Multi-Gene Panel	Progressive gait, peripheral neuropathy, dysarthria	Rare	Tens of thousands	Typically before 40 years
7	ARSACS	SACS	1978	Multi-Gene Panel	Spasticity, ataxia, retinal changes	Rare	Rare	Mean: ~6 years; Range: 0–40 years
8	Ataxia-Telangiectasia (A-T)	ATM	1957	Standard Gene Panel	Cerebellar ataxia, immune issues, telangiectasias	Rare	Few thousand	Early childhood
9	ATX-FXN2 (newly defined)	FXN2	2023	Multi-Gene Panel	Overlap with FA	Rare	Unknown
10	CANVAS	RFC1	2011	Multi-Gene Panel	Sensory ataxia, bilateral vestibular loss, chronic cough	Rare	Likely thousands	Mean: ~50 years
11	Episodic Ataxia Type 1 (EA1)	KCNA1	1994	Multi-Gene Panel	Brief episodes, muscle twitching	<1%	Rare	Childhood or early adolescence; Average: ~8 years
12	Episodic Ataxia Type 2 (EA2)	CACNA1A	1997	Standard Gene Panel	Long episodes, vertigo	<1%	Rare	Onset varies; often in childhood or adolescence
13	Friedreich's Ataxia (FA)	FXN	1863	Standard Gene Panel	Limb/gait ataxia, cardiomyopathy, scoliosis	40-50%	15,000–20,000	Typical: 10–15 years
14	PNKP Ataxia	PNKP	2016	Multi-Gene Panel	Ataxia, seizures, microcephaly	Rare	Rare	7–14 years
15	POLG-related Ataxia	POLG	2001	Multi-Gene Panel	Ataxia, epilepsy, neuropathy	Rare	Rare	Median: 2 years; Range: 1 month to 36 years
16	SCA1	ATXN1	1993	Standard Gene Panel	Dysarthria, gait imbalance	5-6%	2,000–3,000	30s–40s
17	SCA10	ATXN10	1996	Multi-Gene Panel	Ataxia, seizures	<1%	Few hundred–thousand	10–50 years
18	SCA12	PPP2R2B	1999	Multi-Gene Panel	Tremor, cerebellar ataxia	<1%	Rare	33 years (range: 8–55)
19	SCA13	KCNC3	2000	Multi-Gene Panel	Childhood onset, slowly progressive	<1%	Rare	Childhood or early adolescence
20	SCA14	PRKCG	2003	Multi-Gene Panel	Slow progression, cognitive effects	<1%	Rare	Adulthood (typically 30s–40s)
21	SCA15	ITPR1	2000	Multi-Gene Panel	Pure cerebellar ataxia	<1%	Rare	Adulthood (typically 30s–50s)
22	SCA17	TBP	1999	Multi-Gene Panel	Ataxia, psychiatric symptoms	<1%	Rare	Adulthood (mean: mid-30s)
23	SCA19/22	KCND3	2004	Multi-Gene Panel	Late onset ataxia, cognitive involvement	<1%	Rare	Adulthood (typically 30s–50s)
24	SCA2	ATXN2	1997	Standard Gene Panel	Slow saccades, tremor	6-7%	3,000–4,000	30s–40s (earlier onset with larger repeats)
25	SCA21	TMEM240	1998	Multi-Gene Panel	Ataxia, mild intellectual disability	Rare	Rare	Adulthood (mean: ~30s–40s)
26	SCA23	PDYN	2000	Multi-Gene Panel	Late onset, pure cerebellar symptoms	Rare	Rare	Adulthood (typically 30s–50s)
27	SCA26	Unknown	2000	Not Available	Pure cerebellar ataxia	Rare	Rare	Adulthood (mean onset ~42 years)
28	SCA27	FGF14	2004	Multi-Gene Panel	Episodic ataxia, tremor, cognitive issues	Rare	Rare	Adulthood (mean onset ~40 years)
29	SCA27B	FGF14	2020	Multi-Gene Panel	Episodic or progressive ataxia, intention tremor, vertigo or nystagmus.	Rare, but new	Just Diagnosied	Adulthood (recently described; typically mid-life)
30	SCA28	AFG3L2	2006	Multi-Gene Panel	Slow progressive ataxia, oculomotor signs	1.5%	Few hundred	Adulthood (mean: ~35–45 years)
31	SCA3	ATXN3	1994	Standard Gene Panel	Spasticity, dystonia	20-25%	8,000–10,000	Mean: 34.8 years (range: 12–63 years)
32	SCA31	BEAN1	2000	Multi-Gene Panel	Late-onset cerebellar ataxia	Mostly in Japan	Rare	Adulthood (mean: ~58 years; mostly in Japan)
33	SCA36	NOP56	2000	Multi-Gene Panel	Ataxia with hearing loss	Rare	Rare	Adulthood (mean: 50s; often presents after age 40)
34	SCA38	ELOVL5	2004	Multi-Gene Panel	Slow progression, foot deformities	Rare	Rare	Adulthood (mean: ~40 years)
35	SCA4	ZFHX3	2003	Multi-Gene Panel	Gait ataxia, sensory neuropathy	<1%	Rare	Adulthood (30s–50s)
36	SCA42	CACNA1G	1996	Multi-Gene Panel	Mild cerebellar signs, slow progression	Rare	Rare	Adulthood (mean: ~40 years)
37	SCA5	SPTBN2	1993	Multi-Gene Panel	Slowly progressive ataxia	<1%	Rare	Adulthood (onset can vary; some in early childhood)
38	SCA6	CACNA1A	1997	Standard Gene Panel	Pure cerebellar ataxia	4-5%	1,000–2,000	Typically 40s–60s (late-onset)
39	SCA7	ATXN7	1999	Multi-Gene Panel	Vision loss, ataxia	2-3%	500–1,500	Variable: can range from childhood to 40s (larger repeats = earlier onset)
40	SCA8	ATXN8OS	2018	Multi-Gene Panel	Cerebellar ataxia, variable expressivity	<1%	Rare	Mean: ~38.3 years (range: infancy to 70s)
41	STUB1-related Ataxia (SCA48)	STUB1	2016	Multi-Gene Panel	Cognitive decline, cerebellar ataxia	Rare	Rare	Onset varies; often in adulthood
42	SYNE1 Ataxia	SYNE1	2007	Multi-Gene Panel	Cerebellar ataxia, slow progression	Rare	Rare	Onset varies; often in adulthood
43						Listed % = 96%
44						Pie Chart
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