Insecticide resistance adjustment [March 2023] (public)

	A	B	C	D	E	F	G	H	I	J	K	L
1	Insecticide resistance adjustment including PBO and other Dual AI nets	Uganda	Togo	Nigeria	Chad	Democratic Republic of the Congo	Guinea	Cameroon	Madagascar	Malawi	South Sudan	Zambia
2	Synergist bioassay results (IR Mapper data), 2015-2019
3	Number of synergist bioassays conducted (with matching bioassays with pyrethroid insecticide only)	43	4	203	8	32	4	22	38	9	0	6
4	Average mosquito mortality in bioassays with pyrethroid insecticide + PBO	95%	93%	93%	55%	96%	90%	69%	99%	83%	96%	100%
5	Average mosquito mortality in same bioassays with pyrethroid insecticide only	51%	11%	69%	43%	56%	60%	25%	82%	20%	53%	31%
6	Initial proportion of resistance that remains when using PBO (tested areas)	9%	8%	24%	80%	9%	26%	40%	3%	21%	9%	0%
7
8	External validity adjustments for country representativeness
9	Number of test sites with confirmed pyrethroid insecticide resistance (IR Mapper data, 2015-2019)	75	19	243	25	124	26	91	23	80	0	58
10	Number of test sites without confirmed pyrethroid insecticide resistance (IR Mapper data, 2015-2019)	1	0	146	0	30	8	7	168	9	0	12
11	Proportion of test sites with confirmed pyrethroid insecticide resistance (IR Mapper data, 2015-2019)	99%	100%	62%	100%	81%	76%	93%	12%	90%	90%	83%
12	Proportion of sites detected to have relevant resistance mechanism (WHO Malaria Threat Map data, 2010-2017)	83%	79%	79%	71%	100%	79%	90%	100%	100%	92%	100%
13	Estimated proportion of country where PBO nets are more effective than standard LLINs	82%	79%	49%	71%	81%	61%	84%	12%	90%	81%	83%
14
15	Estimated adjustment incorporating adjustment for PBO and other Dual AI nets
16	Reduction in effectiveness due to insecticide resistance for standard LLINs	45%	61%	22%	62%	40%	27%	49%	8%	45%	37%	31%
17	Reduction in effectiveness due to insecticide resistance in areas where PBO nets are effective	4%	5%	5%	50%	4%	7%	20%	0%	10%	3%	0%
18	Reduction in effectiveness due to insecticide resistance with chlorfenapyr nets	0%	0%	0%	0%	0%	0%	0%	0%	0%	0%	0%
19	Reduction in effectiveness due to insecticide resistance with other Dual AI nets	45%	61%	22%	62%	40%	27%	49%	8%	45%	37%	31%
20	Proportion of PBO nets purchased	100%	50%	100%	30%	50%	30%	60%	20%	80%	19%	80%
21	Proportion of chlorfenapyr nets purchased	0%	0%	0%	0%	45%	0%	0%	0%	0%	0%	0%
22	Proportion of other Dual AI nets purchased	0%	0%	0%	0%	5%	0%	0%	0%	0%	0%	0%
23	Proportion of standard LLINs purchased	0%	50%	0%	70%	0%	70%	40%	80%	20%	81%	20%
24	Proportion of PBO nets distributed to areas where PBO nets are effective	82%	50%	49%	30%	50%	30%	60%	12%	80%	19%	80%
25
26	Final reduction in effectiveness due to insecticide resistance including PBO an other Dual AI nets (entire country)	11%	33%	14%	59%	4%	21%	32%	7%	17%	31%	6%
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100