Malaria Molecules, Click on "OSM Number" to see visualisation
 Share
The version of the browser you are using is no longer supported. Please upgrade to a supported browser.Dismiss

 
View only
 
 
ABCDEFGHIJKLMNOPQRSTUVWXYZAAABACADAEAFAGAHAIAJAKALAMANAOAPAQARASATAUAVAWAXAYAZBABBBCBDBEBFBGBHBIBJBKBLBMBNBOBPBQBRBSBTBUBVBW
1
OSM IDInternal IDPubChem CIDMMV IDSMILESInChIIChI Key
Series
AssaysPfaI EC50 (Inh)Pfal IC50 (GSK)Pfal IC50 (Syngene)Pfal IC50 (Dundee)Pfal IC50 (Avery)Pfal (K1) IC50 (Avery)Pfal IC50 (Ralph)Pfal IC50 (Guy)Pfal (K1) IC50 (Guy)Pfal IC50 (Batra)Pfal (K1) IC50 (Batra)Pfal (3D7) IC50 (Broad)Pfal (Dd2) IC50 (Broad)PfaI EC50 uMol (Mean) QualifierPfaI EC50 uMol (Mean)Single Shot Inhibition %PRR (Rate of Killing)PfATP4 'Test Set'
Ion Regulation (ANU)
DHODHLate Stage Gametocyte (Avery)Pb Liver StageHepG2
Cytotox HEK293 (120)
Cytotox HEK293 (40)Cytotox Vero MTTCytotox THP1hERG pIC50t1/2 HLM (Monash)t1/2 HLM (Inh)t1/2 MLM (Monash)t1/2 RLM (Inh)t1/2 HCH (Monash)t1/2 RCH (Monash)t1/2 plasma Humant1/2 plasma MouseCLint HLM (Monash)
%remain plasma Human
%remain plasma Mouse
CLint HLM (Inh)CLint MLM (Monash)CLint RLM (Inh)CLint HCH (Monash)CLint RCH (Monash)
EH H M'some (Monash)
EH M M'some (Monash)
EH H H'cyte (Monash)
EH R H'cyte (Monash)
LogD 3.0 (Monash)LogD 7.4 (Monash)
Sol 2.0 ug/mL (Monash)
Sol 6.5 ug/mL (Monash)
Sol 6.8 uM (Inh)Sol 7.4 uM (Inh)cPPB % (Monash)CL Rat (Inh)Vss Rat (Inh)T1/2 Rat (Inh)Tmax Rat (Inh)Oral F Rat (Inh)Dofetilide (Inh)Cerep (Inh)Vivo NOD/SCID ED90
Vivo Berghei %activity
Vivo Parasit Cl
Aldehyde Oxidase
CLint,app (µL/min/mg)
2
OSM-S-5
TCMDC123812; CHEMBL549220; PMY10; JRC3; AEW5
2434563MMV019247FC1=CC=C(N2C(C)=CC(C(OCC(N)=O)=O)=C2C)C=C1
InChI=1S/C15H15FN2O3/c1-9-7-13(15(20)21-8-14(17)19)10(2)18(9)12-5-3-11(16)4-6-12/h3-7H,8H2,1-2H3,(H2,17,19)
YSUCFIZUNLQZDX-UHFFFAOYSA-N
1
0.818; 0.177
0.4040.3750.610.5810.6410.5222Moderate-slowANo>5075% at 60 micromolar24, 149.8, 18200<4.559nd114291002550-10050-1006
3
OSM-S-106MNB6-744528665MMV025100NC1=C2C(C=C(C3=CC(S(N)(=O)=O)=CC=C3)S2)=NC=N1
InChI=1S/C12H10N4O2S2/c13-12-11-9(15-6-16-12)5-10(19-11)7-2-1-3-8(4-7)20(14,17)18/h1-6H,(H2,13,15,16)(H2,14,17,18)
MQMXDJVOZKMSNT-UHFFFAOYSA-N
30.0880.130.0360.08466666667102<5.00>25523>375<776<1<0.220.62<0.071.450-1006.3-12.5
4
OSM-S-410MMV1557863FC(F)OC(C=C1)=CC=C1C2=NN=C3C(NC=C(C(NC4=CC=C(Cl)C=C4)=O)N32)=O
InChI=1S/C19H12ClF2N5O3/c20-11-3-5-12(6-4-11)24-17(28)14-9-23-18(29)16-26-25-15(27(14)16)10-1-7-13(8-2-10)30-19(21)22/h1-9,19H,(H,23,29)(H,24,28)
SOVUBMPMKMEPEE-UHFFFAOYSA-N
4>5#DIV/0!
5
OSM-S-411MMV1557864
FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(C(NC4=CC=[N+]([O-])C(C(F)(F)F)=C4)=O)N32
InChI=1S/C19H11F5N6O3/c20-18(21)33-12-3-1-10(2-4-12)16-28-27-15-9-25-8-13(30(15)16)17(31)26-11-5-6-29(32)14(7-11)19(22,23)24/h1-9,18H,(H,26,31)
HAVDPBNWKHGTHN-UHFFFAOYSA-N
42.072.07
6
OSM-S-412DGS 25-4, DGS 43-4MMV1557865FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC(CO)C4=CC=C(O)C=C4)N32
InChI=1S/C21H18F2N4O4/c22-21(23)31-17-7-3-14(4-8-17)20-26-25-18-9-24-10-19(27(18)20)30-12-15(11-28)13-1-5-16(29)6-2-13/h1-10,15,21,28-29H,11-12H2
BCDILCAJSSYWKE-UHFFFAOYSA-N
44.124.12
7
OSM-S-391EGT 176-1MMV1557931IC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCC4=CC(F)=C(F)C=C4)N32InChI=1S/C19H13F2IN4O/c20-15-6-1-12(9-16(15)21)7-8-27-18-11-23-10-17-24-25-19(26(17)18)13-2-4-14(22)5-3-13/h1-6,9-11H,7-8H2
SYOXDOQMLHMQGB-UHFFFAOYSA-N
40.350.35
8
OSM-S-392EGT 190-3MMV1557932FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC(C4=CC(F)=C(F)C=C4)=O)N32InChI=1S/C20H12F4N4O3/c21-14-6-3-12(7-15(14)22)16(29)10-30-18-9-25-8-17-26-27-19(28(17)18)11-1-4-13(5-2-11)31-20(23)24/h1-9,20H,10H2
OPCIMEMUOABUMK-UHFFFAOYSA-N
40.830.83
9
OSM-S-393EGT 191-1MMV1557933FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC(OC)(OC)C4=CC(F)=C(F)C=C4)N32InChI=1S/C22H18F4N4O4/c1-31-22(32-2,14-5-8-16(23)17(24)9-14)12-33-19-11-27-10-18-28-29-20(30(18)19)13-3-6-15(7-4-13)34-21(25)26/h3-11,21H,12H2,1-2H3
HFRRKTROCJVLKP-UHFFFAOYSA-N
40.160.16
10
OSM-S-394EGT 212-1MMV1557934FS(F)(F)(F)(F)C(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCC4=CC=CC=C4)N32InChI=1S/C19H15F5N4OS/c20-30(21,22,23,24)16-8-6-15(7-9-16)19-27-26-17-12-25-13-18(28(17)19)29-11-10-14-4-2-1-3-5-14/h1-9,12-13H,10-11H2
PEMORNCGKKXBCP-UHFFFAOYSA-N
40.480.48
11
OSM-S-395EGT 213-1MMV1557935FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCC4(CC5C6)CC6C[C@@H](C5)C4)N32InChI=1S/C24H26F2N4O2/c25-23(26)32-19-3-1-18(2-4-19)22-29-28-20-13-27-14-21(30(20)22)31-6-5-24-10-15-7-16(11-24)9-17(8-15)12-24/h1-4,13-17,23H,5-12H2/t15-,16?,17?,24?
BSXLJNOXQMXUOB-CRFYJIHUSA-N
42.152.15
12
OSM-S-396EGT 215-1MMV1557936FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OC(C)CC4=CC=CC=C4)N32InChI=1S/C21H18F2N4O2/c1-14(11-15-5-3-2-4-6-15)28-19-13-24-12-18-25-26-20(27(18)19)16-7-9-17(10-8-16)29-21(22)23/h2-10,12-14,21H,11H2,1H3
HJOHTEUEFDSADX-UHFFFAOYSA-N
40.450.45
13
OSM-S-397EGT 220-1MMV1557937FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC45C[C@@H](C[C@@H](C5)C6)C[C@@H]6C4)N32InChI=1S/C23H24F2N4O2/c24-22(25)31-18-3-1-17(2-4-18)21-28-27-19-11-26-12-20(29(19)21)30-13-23-8-14-5-15(9-23)7-16(6-14)10-23/h1-4,11-12,14-16,22H,5-10,13H2/t14-,15+,16-,23?
PIOOGPDPQVQAFQ-QUXYOMGYSA-N
44.84.8
14
OSM-S-398EGT 222-1MMV1557938FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCC4[C@@H]5C=C[C@@H](C5)C4)N32InChI=1S/C21H20F2N4O2/c22-21(23)29-17-5-3-14(4-6-17)20-26-25-18-11-24-12-19(27(18)20)28-8-7-16-10-13-1-2-15(16)9-13/h1-6,11-13,15-16,21H,7-10H2/t13-,15+,16?/m0/s1
CLOKKOVBNPXONV-GVJPCGBOSA-N
40.490.49
15
OSM-S-399EGT 224-1MMV1557939CC1(C)[C@@H]2C[C@H]1C(CCOC3=CN=CC4=NN=C(C5=CC=C(OC(F)F)C=C5)N43)=CC2InChI=1S/C23H24F2N4O2/c1-23(2)16-6-3-14(18(23)11-16)9-10-30-20-13-26-12-19-27-28-21(29(19)20)15-4-7-17(8-5-15)31-22(24)25/h3-5,7-8,12-13,16,18,22H,6,9-11H2,1-2H3/t16-,18-/m0/s1
PQILDBPUDLGKJU-WMZOPIPTSA-N
41.281.28
16
OSM-S-400EGT 225-1MMV1557940FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC(C4=CC=CC=C4)=O)N32InChI=1S/C20H14F2N4O3/c21-20(22)29-15-8-6-14(7-9-15)19-25-24-17-10-23-11-18(26(17)19)28-12-16(27)13-4-2-1-3-5-13/h1-11,20H,12H2
MQSMCJANEPVRGE-UHFFFAOYSA-N
41.371.37
17
OSM-S-401SSP 6a1MMV1557941ClC(C=C1)=CC(Cl)=C1C2=NN=C3C=NC=C(OCC45C[C@@H](C[C@@H](C5)C6)C[C@@H]6C4)N32InChI=1S/C22H22Cl2N4O/c23-16-1-2-17(18(24)6-16)21-27-26-19-10-25-11-20(28(19)21)29-12-22-7-13-3-14(8-22)5-15(4-13)9-22/h1-2,6,10-11,13-15H,3-5,7-9,12H2/t13-,14+,15-,22?
XRHQAPBKYTXPOW-HBJUSLLUSA-N
488
18
OSM-S-402SSP 6a2MMV1557942ClC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC45C[C@@H](C[C@@H](C5)C6)C[C@@H]6C4)N32InChI=1S/C22H23ClN4O/c23-18-3-1-17(2-4-18)21-26-25-19-11-24-12-20(27(19)21)28-13-22-8-14-5-15(9-22)7-16(6-14)10-22/h1-4,11-12,14-16H,5-10,13H2/t14-,15+,16-,22?
MFXXXMMQULKXIX-GGTBJBEQSA-N
42.532.53
19
OSM-S-403SSP 6c1MMV1557943CC1(C)[C@@H]2C[C@H]1C(CCOC3=CN=CC4=NN=C(C5=C(Cl)C=C(Cl)C=C5)N43)=CC2InChI=1S/C22H22Cl2N4O/c1-22(2)14-4-3-13(17(22)9-14)7-8-29-20-12-25-11-19-26-27-21(28(19)20)16-6-5-15(23)10-18(16)24/h3,5-6,10-12,14,17H,4,7-9H2,1-2H3/t14-,17-/m0/s1
OYFPJLPMJIFAIS-YOEHRIQHSA-N
48.248.24
20
OSM-S-404SSP 6c2MMV1557944CC1(C)[C@@H]2C[C@H]1C(CCOC3=CN=CC4=NN=C(C5=CC=C(Cl)C=C5)N43)=CC2InChI=1S/C22H23ClN4O/c1-22(2)16-6-3-14(18(22)11-16)9-10-28-20-13-24-12-19-25-26-21(27(19)20)15-4-7-17(23)8-5-15/h3-5,7-8,12-13,16,18H,6,9-11H2,1-2H3/t16-,18-/m0/s1
BDWPPKIAXRRNII-WMZOPIPTSA-N
41.051.05
21
OSM-S-405SSP 6d1MMV1557945ClC(C=C1)=CC(Cl)=C1C2=NN=C3C=NC=C(OCC4C[C@H]5C=C[C@@H]4C5)N32InChI=1S/C19H16Cl2N4O/c20-14-3-4-15(16(21)7-14)19-24-23-17-8-22-9-18(25(17)19)26-10-13-6-11-1-2-12(13)5-11/h1-4,7-9,11-13H,5-6,10H2/t11-,12+,13?/m0/s1
OLAUIVKJLBCHFE-LAGVYOHYSA-N
49.559.55
22
OSM-S-406SSP 6d2MMV1557946ClC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC4C[C@H]5C=C[C@@H]4C5)N32InChI=1S/C19H17ClN4O/c20-16-5-3-13(4-6-16)19-23-22-17-9-21-10-18(24(17)19)25-11-15-8-12-1-2-14(15)7-12/h1-6,9-10,12,14-15H,7-8,11H2/t12-,14+,15?/m0/s1
OWTVMOKESSEJOP-DJIKBVBFSA-N
40.620.62
23
OSM-S-408CG60-2MMV1557947C12=NN=C(C3=CC=NC=C3)N1C(OCCC4=CC=CC=C4)=CN=C2
InChI=1S/C18H15N5O/c1-2-4-14(5-3-1)8-11-24-17-13-20-12-16-21-22-18(23(16)17)15-6-9-19-10-7-15/h1-7,9-10,12-13H,8,11H2
BSTOZULDVQMNLS-UHFFFAOYSA-N
4>10#DIV/0!
24
OSM-S-407CG59-1MMV1557948O=C(NC1=CC=NC=C1)C2=CN=CC3=NN=C(C4=CC=CC=C4)N32
InChI=1S/C17H12N6O/c24-17(20-13-6-8-18-9-7-13)14-10-19-11-15-21-22-16(23(14)15)12-4-2-1-3-5-12/h1-11H,(H,18,20,24)
HSTAGCWQAIXJQM-UHFFFAOYSA-N
4>10#DIV/0!
25
OSM-S-415EGT 249-1; MK009-1MMV1557949FC(C=C1)=C(F)C=C1CCOC2=CN=CC3=NN=C(C4=CC=CC=C4)N32
InChI=1S/C19H14F2N4O/c20-15-7-6-13(10-16(15)21)8-9-26-18-12-22-11-17-23-24-19(25(17)18)14-4-2-1-3-5-14/h1-7,10-12H,8-9H2
RGEIFMMWUNGFHD-UHFFFAOYSA-N
42.152.15
26
OSM-S-409EGT 237-2MMV1557950FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OC/C(C4=CC=CC=C4)=N/O)N32
InChI=1S/C20H15F2N5O3/c21-20(22)30-15-8-6-14(7-9-15)19-25-24-17-10-23-11-18(27(17)19)29-12-16(26-28)13-4-2-1-3-5-13/h1-11,20,28H,12H2/b26-16-
VJSBQKQNONLQQJ-QQXSKIMKSA-N
4>10#DIV/0!
27
OSM-S-414P2MMV1557951FC(C=C1)=C(F)C=C1[C@H](OC)COC2=CN=CC3=NN=C(C4=CC=C(C#N)C=C4)N32
InChI=1S/C21H15F2N5O2/c1-29-18(15-6-7-16(22)17(23)8-15)12-30-20-11-25-10-19-26-27-21(28(19)20)14-4-2-13(9-24)3-5-14/h2-8,10-11,18H,12H2,1H3
PERKBMZWWUEZNJ-UHFFFAOYSA-N
40.890.89
28
OSM-S-413P1MMV1557952FC(C=C1)=C(F)C=C1[C@@H](OC)COC2=CN=CC3=NN=C(C4=CC=C(C#N)C=C4)N32
InChI=1S/C21H15F2N5O2/c1-29-18(15-6-7-16(22)17(23)8-15)12-30-20-11-25-10-19-26-27-21(28(19)20)14-4-2-13(9-24)3-5-14/h2-8,10-11,18H,12H2,1H3
PERKBMZWWUEZNJ-UHFFFAOYSA-N
4>10#DIV/0!
29
OSM-S-416P1+P2MMV1557953FC(C=C1)=C(F)C=C1C(OC)COC2=CN=CC3=NN=C(C4=CC=C(C#N)C=C4)N32
InChI=1S/C21H15F2N5O2/c1-29-18(15-6-7-16(22)17(23)8-15)12-30-20-11-25-10-19-26-27-21(28(19)20)14-4-2-13(9-24)3-5-14/h2-8,10-11,18H,12H2,1H3
PERKBMZWWUEZNJ-UHFFFAOYSA-N
40.430.43
30
OSM-S-417EGT 243-1MMV1557962C1(N2CCCCC2)=NC=CN3C1=NN=C3OCCC4=CC=CC=C4
InChI=1S/C18H21N5O/c1-3-7-15(8-4-1)9-14-24-18-21-20-17-16(19-10-13-23(17)18)22-11-5-2-6-12-22/h1,3-4,7-8,10,13H,2,5-6,9,11-12,14H2
UGDHWGVLTGKDHK-UHFFFAOYSA-N
4>10#DIV/0!
31
OSM-S-418EGT 257-1MMV1576784FC(OC1=CC=C(C2=NN=C3C=NC=C(N32)OCC[C]4[CH]BBBBBBBBBB4)C=C1)F
InChI=1S/C16H22B10F2N4O2/c27-16(28)34-12-3-1-10(2-4-12)15-31-30-13-8-29-9-14(32(13)15)33-6-5-11-7-17-19-21-23-25-26-24-22-20-18-11/h1-4,7-9,16-26H,5-6H2
AGPVLTOPROUGPQ-UHFFFAOYSA-N
40.050.055.447<285249>86640.91>0.940.234.41.6-3.1<1.6
32
OSM-S-419EGT 236-2MMV1576785FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC(N4CCOCC4)C5=CC=CC=C5)N32
InChI=1S/C24H23F2N5O3/c25-24(26)34-19-8-6-18(7-9-19)23-29-28-21-14-27-15-22(31(21)23)33-16-20(17-4-2-1-3-5-17)30-10-12-32-13-11-30/h1-9,14-15,20,24H,10-13,16H2
NLNZVWQRJHUCOA-UHFFFAOYSA-N
41.581.58
33
OSM-S-421EGT 263-1MMV1576786FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCN4CC5(COC5)C4)N32
InChI=1S/C19H19F2N5O3/c20-18(21)29-14-3-1-13(2-4-14)17-24-23-15-7-22-8-16(26(15)17)28-6-5-25-9-19(10-25)11-27-12-19/h1-4,7-8,18H,5-6,9-12H2
CWOUGAWUCYKRFC-UHFFFAOYSA-N
4>10#DIV/0!
34
OSM-S-420EGT 262-1MMV1576787FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC4=CC=C(CO)C=C4)N32
InChI=1S/C20H16F2N4O3/c21-20(22)29-16-7-5-15(6-8-16)19-25-24-17-9-23-10-18(26(17)19)28-12-14-3-1-13(11-27)2-4-14/h1-10,20,27H,11-12H2
VIQWBWLDUDXSBJ-UHFFFAOYSA-N
4>10#DIV/0!
35
OSM-S-422EGT 265-1MMV1576788FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCC4COC4)N32
InChI=1S/C17H16F2N4O3/c18-17(19)26-13-3-1-12(2-4-13)16-22-21-14-7-20-8-15(23(14)16)25-6-5-11-9-24-10-11/h1-4,7-8,11,17H,5-6,9-10H2
VMXSRABLXQMXLK-UHFFFAOYSA-N
4>10#DIV/0!
36
OSM-S-423EGT 273-1MMV1576789FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC4(OCCO4)C5=CC(F)=C(F)C=C5)N32
InChI=1S/C22H16F4N4O4/c23-16-6-3-14(9-17(16)24)22(32-7-8-33-22)12-31-19-11-27-10-18-28-29-20(30(18)19)13-1-4-15(5-2-13)34-21(25)26/h1-6,9-11,21H,7-8,12H2
UAZNIGDYRZOARG-UHFFFAOYSA-N
40.670.67
37
OSM-S-424EGT 274-1MMV1576790
FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC/C4=C/BBBBB[BH]5[BH]([H]5)BB4)N32.[Cs+]
InChI=1S/C16H22B9F2N4O2.Cs/c26-16(27)33-12-3-1-10(2-4-12)15-30-29-13-8-28-9-14(31(13)15)32-6-5-11-7-17-19-20-21-23-25-24(34-25)22-18-11;/h1-4,7-9,16-25H,5-6H2;/q;+1/b11-7-;
GZUNPULXOLJYSG-AJULUCINSA-N
41.91.9
38
OSM-S-430EGT 181-3MMV1576791FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC(N(CC)CC)C4=CC(F)=C(F)C=C4)N32InChI=1S/C24H23F4N5O2/c1-3-32(4-2)20(16-7-10-18(25)19(26)11-16)14-34-22-13-29-12-21-30-31-23(33(21)22)15-5-8-17(9-6-15)35-24(27)28/h5-13,20,24H,3-4,14H2,1-2H3FFKUJTSUMDVIQH-UHFFFAOYSA-N4>10#DIV/0!
39
OSM-S-431EGT 182-3MMV1576792FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC(N(CC)C)C4=CC(F)=C(F)C=C4)N32InChI=1S/C23H21F4N5O2/c1-3-31(2)19(15-6-9-17(24)18(25)10-15)13-33-21-12-28-11-20-29-30-22(32(20)21)14-4-7-16(8-5-14)34-23(26)27/h4-12,19,23H,3,13H2,1-2H3XPBTWBXREHLVRP-UHFFFAOYSA-N48.858.85
40
OSM-S-494MK014-1MMV1576793FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(C(N)=O)C=C4)N32)=CC=C1F
InChI=1S/C20H15F2N5O2/c21-15-6-1-12(9-16(15)22)7-8-29-18-11-24-10-17-25-26-20(27(17)18)14-4-2-13(3-5-14)19(23)28/h1-6,9-11H,7-8H2,(H2,23,28)
INLVQLIAJLYDGP-UHFFFAOYSA-N
4>10#DIV/0!
41
OSM-S-495MK016-1MMV1576794FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC(C(N)=O)=CC=C4)N32)=CC=C1F
InChI=1S/C20H15F2N5O2/c21-15-5-4-12(8-16(15)22)6-7-29-18-11-24-10-17-25-26-20(27(17)18)14-3-1-2-13(9-14)19(23)28/h1-5,8-11H,6-7H2,(H2,23,28)
SUVZMBHYRLCWQO-UHFFFAOYSA-N
4>10#DIV/0!
42
OSM-S-496MK017-1MMV1576795FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(C(N(C)C)=O)C=C4)N32)=CC=C1F
InChI=1S/C22H19F2N5O2/c1-28(2)22(30)16-6-4-15(5-7-16)21-27-26-19-12-25-13-20(29(19)21)31-10-9-14-3-8-17(23)18(24)11-14/h3-8,11-13H,9-10H2,1-2H3
VILLYIKHHVUPAT-UHFFFAOYSA-N
43.693.69
43
OSM-S-432MK005, EGT 152MMV1576796BrC1=NN=C2C=NC=C(OCCC3=CC(F)=C(F)C=C3)N21InChI=1S/C13H9BrF2N4O/c14-13-19-18-11-6-17-7-12(20(11)13)21-4-3-8-1-2-9(15)10(16)5-8/h1-2,5-7H,3-4H2MNOZFILPXCZGRJ-UHFFFAOYSA-N4>10#DIV/0!
44
OSM-S-503CG74-1MMV1577514FC(C1=NC=C(OCCC2=CC=CC=C2)N3C1=NN=C3C4=CC=NC=C4)(F)F
InChI=1S/C19H14F3N5O/c20-19(21,22)16-18-26-25-17(14-6-9-23-10-7-14)27(18)15(12-24-16)28-11-8-13-4-2-1-3-5-13/h1-7,9-10,12H,8,11H2
CRIOEXIRGOUJPE-UHFFFAOYSA-N
4>10#DIV/0!
45
OSM-S-504CG82-5MMV1577566FC(OC(C=C1)=CC=C1C2=NN=C3C(C(F)(F)F)=NC=C(OCCC4=CC=CC=C4)N32)F
InChI=1S/C21H15F5N4O2/c22-20(23)32-15-8-6-14(7-9-15)18-28-29-19-17(21(24,25)26)27-12-16(30(18)19)31-11-10-13-4-2-1-3-5-13/h1-9,12,20H,10-11H2
JQNJPMCZRDTAFX-UHFFFAOYSA-N
4>10#DIV/0!
46
OSM-S-505CG86-1MMV1577567OC1=NC=C(OCCC2=CC=CC=C2)N3C1=NN=C3C4=CC=C(OC(F)F)C=C4
InChI=1S/C20H16F2N4O3/c21-20(22)29-15-8-6-14(7-9-15)17-24-25-18-19(27)23-12-16(26(17)18)28-11-10-13-4-2-1-3-5-13/h1-9,12,20H,10-11H2,(H,23,27)
AUEFCDYZHUAYCQ-UHFFFAOYSA-N
4>10#DIV/0!
47
OSM-S-510MK027-1MMV1577568
FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(C(N5CCN(C)CC5)=O)C=C4)N32)=CC=C1F
InChI=1S/C25H24F2N6O2/c1-31-9-11-32(12-10-31)25(34)19-5-3-18(4-6-19)24-30-29-22-15-28-16-23(33(22)24)35-13-8-17-2-7-20(26)21(27)14-17/h2-7,14-16H,8-13H2,1H3
KQGRHFCAJKSETG-UHFFFAOYSA-N
4>10#DIV/0!
48
OSM-S-506MK029-1MMV1577569FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(S(N)(=O)=O)C=C4)N32)=CC=C1F
InChI=1S/C19H15F2N5O3S/c20-15-6-1-12(9-16(15)21)7-8-29-18-11-23-10-17-24-25-19(26(17)18)13-2-4-14(5-3-13)30(22,27)28/h1-6,9-11H,7-8H2,(H2,22,27,28)
LAEXWQNXYFZJGR-UHFFFAOYSA-N
4>10#DIV/0!
49
OSM-S-507MK019-1MMV1577570FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(C(N5CCOCC5)=O)C=C4)N32)=CC=C1F
InChI=1S/C24H21F2N5O3/c25-19-6-1-16(13-20(19)26)7-10-34-22-15-27-14-21-28-29-23(31(21)22)17-2-4-18(5-3-17)24(32)30-8-11-33-12-9-30/h1-6,13-15H,7-12H2
UVYBVUBFTPXZED-UHFFFAOYSA-N
4>10#DIV/0!
50
OSM-S-508MK028-1MMV1577571
FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC(C(N5CCN(C)CC5)=O)=CC=C4)N32)=CC=C1F
InChI=1S/C25H24F2N6O2/c1-31-8-10-32(11-9-31)25(34)19-4-2-3-18(14-19)24-30-29-22-15-28-16-23(33(22)24)35-12-7-17-5-6-20(26)21(27)13-17/h2-6,13-16H,7-12H2,1H3
AGXBROZGFUYMOG-UHFFFAOYSA-N
4>10#DIV/0!
51
OSM-S-509MK023-1MMV1577572FC(F)OC(C=C1)=CC=C1C2=NN=C3C(N4CCOCC4)=NC=CN32
InChI=1S/C16H15F2N5O2/c17-16(18)25-12-3-1-11(2-4-12)13-20-21-15-14(19-5-6-23(13)15)22-7-9-24-10-8-22/h1-6,16H,7-10H2
GXUMGQHMGACMED-UHFFFAOYSA-N
4>10#DIV/0!
52
OSM-S-433EGT 286-1MMV1577573FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCC4C5C6C7C4C8CC5C6C8C7)N32InChI=1S/C25H24F2N4O2/c26-25(27)33-12-3-1-11(2-4-12)24-30-29-18-9-28-10-19(31(18)24)32-6-5-13-20-14-7-17-21(13)23-16(20)8-15(14)22(17)23/h1-4,9-10,13-17,20-23,25H,5-8H2XRVKLGJFLBVBHV-UHFFFAOYSA-N41.081.08
53
OSM-S-497EGT 281-2MMV1577574FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCN4CCNCC4)N32
InChI=1S/C18H20F2N6O2/c19-18(20)28-14-3-1-13(2-4-14)17-24-23-15-11-22-12-16(26(15)17)27-10-9-25-7-5-21-6-8-25/h1-4,11-12,18,21H,5-10H2
PLMTYPFHNQBXCS-UHFFFAOYSA-N
4>10#DIV/0!
54
OSM-S-498EGT 282-1MMV1577575FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCN4CCOCC4)N32
InChI=1S/C18H19F2N5O3/c19-18(20)28-14-3-1-13(2-4-14)17-23-22-15-11-21-12-16(25(15)17)27-10-7-24-5-8-26-9-6-24/h1-4,11-12,18H,5-10H2
SBJHRXFPKNPJRB-UHFFFAOYSA-N
4>10#DIV/0!
55
OSM-S-499EGT 283-1MMV1577576FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCN4CCCCC4)N32
InChI=1S/C19H21F2N5O2/c20-19(21)28-15-6-4-14(5-7-15)18-24-23-16-12-22-13-17(26(16)18)27-11-10-25-8-2-1-3-9-25/h4-7,12-13,19H,1-3,8-11H2
VHKQNGVJPUDTLR-UHFFFAOYSA-N
4>10#DIV/0!
56
OSM-S-500EGT 284-2MMV1577577FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCN4CCCC4)N32
InChI=1S/C18H19F2N5O2/c19-18(20)27-14-5-3-13(4-6-14)17-23-22-15-11-21-12-16(25(15)17)26-10-9-24-7-1-2-8-24/h3-6,11-12,18H,1-2,7-10H2
CBYPWHTZBGGIHQ-UHFFFAOYSA-N
4>10#DIV/0!
57
OSM-S-501EGT 290-1MMV1577578FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCN4CCN(C(OC(C)(C)C)=O)CC4)N32
InChI=1S/C23H28F2N6O4/c1-23(2,3)35-22(32)30-10-8-29(9-11-30)12-13-33-19-15-26-14-18-27-28-20(31(18)19)16-4-6-17(7-5-16)34-21(24)25/h4-7,14-15,21H,8-13H2,1-3H3
IQWMJMCFKRFOAK-UHFFFAOYSA-N
4>10#DIV/0!
58
OSM-S-502EGT 292-1 (f4-8)MMV1577579FC(F)OC(C=C1)=CC=C1C2=NN=C3C(N4C(C=CC=C5)=C5C(CCO)=C4)=NC=CN32
InChI=1S/C22H17F2N5O2/c23-22(24)31-16-7-5-14(6-8-16)19-26-27-21-20(25-10-11-28(19)21)29-13-15(9-12-30)17-3-1-2-4-18(17)29/h1-8,10-11,13,22,30H,9,12H2
RYGYOYDNHPXBSD-UHFFFAOYSA-N
4>8#DIV/0!
59
OSM-S-328EGT 292-1 (f11)MMV1577580FC(F)OC(C=C1)=CC=C1C2=NN=C3C(O)=NC=CN32
InChI=1S/C12H8F2N4O2/c13-12(14)20-8-3-1-7(2-4-8)9-16-17-10-11(19)15-5-6-18(9)10/h1-6,12H,(H,15,19)
NRBGBUNTESVJLL-UHFFFAOYSA-N
4>10#DIV/0!
60
OSM-S-442EGT 295-1MMV1577581FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCCC4CC4)N32InChI=1S/C17H16F2N4O2/c18-17(19)25-13-5-3-12(4-6-13)16-22-21-14-9-20-10-15(23(14)16)24-8-7-11-1-2-11/h3-6,9-11,17H,1-2,7-8H2QIHIEDPHHZEXLP-UHFFFAOYSA-N43.033.03
61
OSM-S-511PF-7091172MMV1577922FC(F)OC(C=C1)=CC=C1C(N23)=NN=C2C=NC=C3OCC(C[C@@H]4C5)[C@@H]5[C@H]6[C@@H]4O6
InChI=1S/C20H18F2N4O3/c21-20(22)28-13-3-1-10(2-4-13)19-25-24-15-7-23-8-16(26(15)19)27-9-12-5-11-6-14(12)18-17(11)29-18/h1-4,7-8,11-12,14,17-18,20H,5-6,9H2/t11-,12?,14-,17-,18+/m1/s1
ODZWUXZHRJYWIV-AUENPLLUSA-N
4>9.8#DIV/0!
62
OSM-S-512PF-7091173MMV1577923FC(F)OC(C=C1)=CC=C1C(N23)=NN=C2C=NC=C3OCC4[C@@H]5[C@@H]6[C@@H](O6)[C@@H](C5)C4
InChI=1S/C20H18F2N4O3/c21-20(22)28-13-3-1-10(2-4-13)19-25-24-15-7-23-8-16(26(15)19)27-9-12-5-11-6-14(12)18-17(11)29-18/h1-4,7-8,11-12,14,17-18,20H,5-6,9H2/t11-,12?,14-,17+,18-/m1/s1
ODZWUXZHRJYWIV-FAXSGNTCSA-N
4>11#DIV/0!>
63
OSM-S-513PF-7091175MMV1577924FC(F)OC1=CC=C(C2=NN=C3N2C(OCCC45C6C7C4C8C7(O)C6C85)=CN=C3)C=C1
InChI=1S/C22H18F2N4O3/c23-20(24)31-10-3-1-9(2-4-10)19-27-26-11-7-25-8-12(28(11)19)30-6-5-21-13-16-14(21)18-15(21)17(13)22(16,18)29/h1-4,7-8,13-18,20,29H,5-6H2
LLMZELBAKVZCME-UHFFFAOYSA-N
4>1#DIV/0!
64
OSM-S-514PF-7091176MMV1577925FC(F)OC1=CC=C(C2=NN=C3N2C(OCCC45C6(O)C7C4C8C7C6C85)=CN=C3)C=C1
InChI=1S/C22H18F2N4O3/c23-20(24)31-10-3-1-9(2-4-10)19-27-26-11-7-25-8-12(28(11)19)30-6-5-21-15-13-14-17(15)22(21,29)18(14)16(13)21/h1-4,7-8,13-18,20,29H,5-6H2
HOJTWLDVMYKZDM-UHFFFAOYSA-N
4>3.3#DIV/0!
65
OSM-S-515EGT 199-5MMV1579336FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC(C(O)=O)C4=CC=CC=C4)N32
InChI=1S/C21H16F2N4O4/c22-21(23)31-15-8-6-14(7-9-15)19-26-25-17-10-24-11-18(27(17)19)30-12-16(20(28)29)13-4-2-1-3-5-13/h1-11,16,21H,12H2,(H,28,29)
FICNFVPYGUTYFV-UHFFFAOYSA-N
43.883.88<5.00>255>255224<7<72<0.22<0.130.11.36.3-12.525-50
66
OSM-S-517MK008-20MMV1579337FC1=CC(CCOC2=CN=CC3=NN=C(N4CCOCC4)N32)=CC=C1F
InChI=1S/C17H17F2N5O2/c18-13-2-1-12(9-14(13)19)3-6-26-16-11-20-10-15-21-22-17(24(15)16)23-4-7-25-8-5-23/h1-2,9-11H,3-8H2
BBKXHWRASNHAOR-UHFFFAOYSA-N
4>19#DIV/0!
67
OSM-S-522MK018-1MMV1579338FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=CC(C(N(C)C)=O)=C4)N32)=CC=C1F
InChI=1S/C22H19F2N5O2/c1-28(2)22(30)16-5-3-4-15(11-16)21-27-26-19-12-25-13-20(29(19)21)31-9-8-14-6-7-17(23)18(24)10-14/h3-7,10-13H,8-9H2,1-2H3
PWLRVFJPMJABKE-UHFFFAOYSA-N
4>25#DIV/0!
68
OSM-S-523MK025-3MMV1579339FC(C=C1)=C(F)C=C1CCOC2=CN=CC3=NN=C(OCCC4=CC(F)=C(F)C=C4)N32
InChI=1S/C21H16F4N4O2/c22-15-3-1-13(9-17(15)24)5-7-30-20-12-26-11-19-27-28-21(29(19)20)31-8-6-14-2-4-16(23)18(25)10-14/h1-4,9-12H,5-8H2
PCFGQRSVXZZXPK-UHFFFAOYSA-N
4>25#DIV/0!
69
OSM-S-524MK034-1MMV1579340FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(N5CCOCC5)C=C4)N32)=CC=C1F
InChI=1S/C23H21F2N5O2/c24-19-6-1-16(13-20(19)25)7-10-32-22-15-26-14-21-27-28-23(30(21)22)17-2-4-18(5-3-17)29-8-11-31-12-9-29/h1-6,13-15H,7-12H2
YZCOBAJWPPWSFU-UHFFFAOYSA-N
4>17#DIV/0!
70
OSM-S-525MK035-1, MK035-2MMV1579341FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C5C(NC=C5)=C4)N32)=CC=C1F
InChI=1S/C21H15F2N5O/c22-16-4-1-13(9-17(16)23)6-8-29-20-12-24-11-19-26-27-21(28(19)20)15-3-2-14-5-7-25-18(14)10-15/h1-5,7,9-12,25H,6,8H2
VHFREJHLTSVZGA-UHFFFAOYSA-N
4
0.086, 0.127
#DIV/0!5.128434205417110.890.90.433.43.1-6.33.1-6.3
71
OSM-S-526MK041-1MMV1579342FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(N)C=C4)N32)=CC=C1F
InChI=1S/C19H15F2N5O/c20-15-6-1-12(9-16(15)21)7-8-27-18-11-23-10-17-24-25-19(26(17)18)13-2-4-14(22)5-3-13/h1-6,9-11H,7-8,22H2
PGJZGRJIPPSPJV-UHFFFAOYSA-N
41313
72
OSM-S-527MK042-1MMV1579343FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(N5CCCCC5)C=C4)N32)=CC=C1F
InChI=1S/C24H23F2N5O/c25-20-9-4-17(14-21(20)26)10-13-32-23-16-27-15-22-28-29-24(31(22)23)18-5-7-19(8-6-18)30-11-2-1-3-12-30/h4-9,14-16H,1-3,10-13H2
IBAQRAIPMINXCX-UHFFFAOYSA-N
4>20#DIV/0!
73
OSM-S-528MK043-1MMV1579344FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(N5CCCC5)C=C4)N32)=CC=C1F
InChI=1S/C23H21F2N5O/c24-19-8-3-16(13-20(19)25)9-12-31-22-15-26-14-21-27-28-23(30(21)22)17-4-6-18(7-5-17)29-10-1-2-11-29/h3-8,13-15H,1-2,9-12H2
MKNMPQGWOUWNLB-UHFFFAOYSA-N
4>22#DIV/0!
74
OSM-S-529MK044-1MMV1579345FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(NC(C)=O)C=C4)N32)=CC=C1F
InChI=1S/C21H17F2N5O2/c1-13(29)25-16-5-3-15(4-6-16)21-27-26-19-11-24-12-20(28(19)21)30-9-8-14-2-7-17(22)18(23)10-14/h2-7,10-12H,8-9H2,1H3,(H,25,29)
PLEIRUOVWBUIKA-UHFFFAOYSA-N
4>25#DIV/0!
75
OSM-S-530MK045-1MMV1579346FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=CC(NC(C)=O)=C4)N32)=CC=C1F
InChI=1S/C21H17F2N5O2/c1-13(29)25-16-4-2-3-15(10-16)21-27-26-19-11-24-12-20(28(19)21)30-8-7-14-5-6-17(22)18(23)9-14/h2-6,9-12H,7-8H2,1H3,(H,25,29)
DFKJCMXUKUTORD-UHFFFAOYSA-N
4>25#DIV/0!
76
OSM-S-518MK048-1MMV1579347FC1=CC(CCOC2=CN=CC3=NN=C(N4CCC(F)(F)CC4)N32)=CC=C1F
InChI=1S/C18H17F4N5O/c19-13-2-1-12(9-14(13)20)3-8-28-16-11-23-10-15-24-25-17(27(15)16)26-6-4-18(21,22)5-7-26/h1-2,9-11H,3-8H2
QEKAFCQAHVHCHN-UHFFFAOYSA-N
41.511.51
77
OSM-S-519MK049-1MMV1579348FC1=CC(CCOC2=CN=CC3=NN=C(N4CCC(F)CC4)N32)=CC=C1F
InChI=1S/C18H18F3N5O/c19-13-3-6-25(7-4-13)18-24-23-16-10-22-11-17(26(16)18)27-8-5-12-1-2-14(20)15(21)9-12/h1-2,9-11,13H,3-8H2
XGYZBGPCRAEWAT-UHFFFAOYSA-N
48.468.46
78
OSM-S-520MK050-1MMV1579349FC1=CC(CCOC2=CN=CC3=NN=C(N4CCC(C(F)(F)F)CC4)N32)=CC=C1F
InChI=1S/C19H18F5N5O/c20-14-2-1-12(9-15(14)21)5-8-30-17-11-25-10-16-26-27-18(29(16)17)28-6-3-13(4-7-28)19(22,23)24/h1-2,9-11,13H,3-8H2
VSNCNIYPDHLNGV-UHFFFAOYSA-N
42.752.75
79
OSM-S-521MK052-1MMV1579350FC1=CC(CCOC2=CN=CC3=NN=C(N4CCN(C)CC4)N32)=CC=C1F
InChI=1S/C18H20F2N6O/c1-24-5-7-25(8-6-24)18-23-22-16-11-21-12-17(26(16)18)27-9-4-13-2-3-14(19)15(20)10-13/h2-3,10-12H,4-9H2,1H3
PXDXCQZMCIITIC-UHFFFAOYSA-N
4>25#DIV/0!
80
OSM-S-531MK054-1MMV1579351FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(N(C)C)C=C4)N32)=CC=C1F
InChI=1S/C21H19F2N5O/c1-27(2)16-6-4-15(5-7-16)21-26-25-19-12-24-13-20(28(19)21)29-10-9-14-3-8-17(22)18(23)11-14/h3-8,11-13H,9-10H2,1-2H3
DWKVYGNKXDMKJI-UHFFFAOYSA-N
45.535.53
81
OSM-S-541PfizerMMV1580315FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC(CO)(O)C4=CC=CC=C4)N32
InChI=1S/C21H18F2N4O4/c22-20(23)31-16-8-6-14(7-9-16)19-26-25-17-10-24-11-18(27(17)19)30-13-21(29,12-28)15-4-2-1-3-5-15/h1-11,20,28-29H,12-13H2
LVBNVRWXODMMAV-UHFFFAOYSA-N
4#DIV/0!
82
OSM-S-532DGS 33-1MMV1580421FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC(CO)C4=CC=CC(OCC5=CC=CC=C5)=C4)N32
InChI=1S/C28H24F2N4O4/c29-28(30)38-23-11-9-20(10-12-23)27-33-32-25-14-31-15-26(34(25)27)37-18-22(16-35)21-7-4-8-24(13-21)36-17-19-5-2-1-3-6-19/h1-15,22,28,35H,16-18H2
MNCMMCAPVFCUDR-UHFFFAOYSA-N
40.0590.059
83
OSM-S-533DGS 32-1MMV1580422FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OCC(CO)C4=CC=CC(O)=C4)N32
InChI=1S/C21H18F2N4O4/c22-21(23)31-17-6-4-13(5-7-17)20-26-25-18-9-24-10-19(27(18)20)30-12-15(11-28)14-2-1-3-16(29)8-14/h1-10,15,21,28-29H,11-12H2
OKGRHDYGIKFDNY-UHFFFAOYSA-N
40.3820.382
84
OSM-S-535EGT 306-1MMV1580423FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OC[C@H](NC(OC(C)(C)C)=O)CC4=CC=CC=C4)N32
InChI=1S/C26H27F2N5O4/c1-26(2,3)37-25(34)30-19(13-17-7-5-4-6-8-17)16-35-22-15-29-14-21-31-32-23(33(21)22)18-9-11-20(12-10-18)36-24(27)28/h4-12,14-15,19,24H,13,16H2,1-3H3,(H,30,34)
SDPYEXOSVNFLTG-UHFFFAOYSA-N
48.68.6
85
OSM-S-536EGT 307-1MMV1580424FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OC[C@H](N)CC4=CC=CC=C4)N32
InChI=1S/C21H19F2N5O2/c22-21(23)30-17-8-6-15(7-9-17)20-27-26-18-11-25-12-19(28(18)20)29-13-16(24)10-14-4-2-1-3-5-14/h1-9,11-12,16,21H,10,13,24H2/t16-/m1/s1
FXPPGJNSMWQGRD-MRXNPFEDSA-N
417175.12
86
OSM-S-537EGT 308-1MMV1580425FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OC[C@@H](NC(OC(C)(C)C)=O)CC4=CC=CC=C4)N32
InChI=1S/C26H27F2N5O4/c1-26(2,3)37-25(34)30-19(13-17-7-5-4-6-8-17)16-35-22-15-29-14-21-31-32-23(33(21)22)18-9-11-20(12-10-18)36-24(27)28/h4-12,14-15,19,24H,13,16H2,1-3H3,(H,30,34)
SDPYEXOSVNFLTG-UHFFFAOYSA-N
41010
87
OSM-S-538EGT 311-1MMV1580426FC(F)OC(C=C1)=CC=C1C2=NN=C3C=NC=C(OC[C@@H](N)CC4=CC=CC=C4)N32
InChI=1S/C21H19F2N5O2/c22-21(23)30-17-8-6-15(7-9-17)20-27-26-18-11-25-12-19(28(18)20)29-13-16(24)10-14-4-2-1-3-5-14/h1-9,11-12,16,21H,10,13,24H2/t16-/m0/s1
FXPPGJNSMWQGRD-INIZCTEOSA-N
42.32.3
88
OSM-S-542MK031-2aMMV1580427FC1=CC(CCOC2=CN=CC3=NN=C(N4C=CC=N4)N32)=CC=C1F
InChI=1S/C16H12F2N6O/c17-12-3-2-11(8-13(12)18)4-7-25-15-10-19-9-14-21-22-16(24(14)15)23-6-1-5-20-23/h1-3,5-6,8-10H,4,7H2
ACHYQCFQKMAIMF-UHFFFAOYSA-N
4>25#DIV/0!
89
OSM-S-543MK031-2bMMV1580428FC(C(F)=C1)=CC=C1CCOC2=NC=CN3C2=NN=C3N4N=CC=C4
InChI=1S/C16H12F2N6O/c17-12-3-2-11(10-13(12)18)4-9-25-15-14-21-22-16(23(14)8-6-19-15)24-7-1-5-20-24/h1-3,5-8,10H,4,9H2
ZXJLKQGJXOAUOQ-UHFFFAOYSA-N
4>19#DIV/0!
90
OSM-S-544MK055-1MMV1580429FC(C=C1)=C(F)C=C1CCOC2=CN=CC3=NN=C(OC4=CC=C(Cl)C=C4)N32
InChI=1S/C19H13ClF2N4O2/c20-13-2-4-14(5-3-13)28-19-25-24-17-10-23-11-18(26(17)19)27-8-7-12-1-6-15(21)16(22)9-12/h1-6,9-11H,7-8H2
ZAKLZMUOIOUUEH-UHFFFAOYSA-N
4>25#DIV/0!
91
OSM-S-545MK062-1MMV1580430FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC(N(C)C)=CC=C4)N32)=CC=C1F
InChI=1S/C21H19F2N5O/c1-27(2)16-5-3-4-15(11-16)21-26-25-19-12-24-13-20(28(19)21)29-9-8-14-6-7-17(22)18(23)10-14/h3-7,10-13H,8-9H2,1-2H3
CHKSIGXRRUITRE-UHFFFAOYSA-N
477
92
OSM-S-546MK063-1MMV1580431FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C5C(NN=C5)=C4)N32)=CC=C1F
InChI=1S/C20H14F2N6O/c21-15-4-1-12(7-16(15)22)5-6-29-19-11-23-10-18-26-27-20(28(18)19)13-2-3-14-9-24-25-17(14)8-13/h1-4,7-11H,5-6H2,(H,24,25)
CGVAIQJJRYJQMC-UHFFFAOYSA-N
40.4340.434
93
OSM-S-547MK064-1MMV1580432FC1=CC(CCOC2=CN=CC3=NN=C(C4=C5C(NC=C5)=CC=C4)N23)=CC=C1F
InChI=1S/C21H15F2N5O/c22-16-5-4-13(10-17(16)23)7-9-29-20-12-24-11-19-26-27-21(28(19)20)15-2-1-3-18-14(15)6-8-25-18/h1-6,8,10-12,25H,7,9H2
BAKHABOPVVJMJZ-UHFFFAOYSA-N
44.94.9
94
OSM-S-548MK065-1MMV1580433FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(Cl)C(N)=C4)N32)=CC=C1F
InChI=1S/C19H14ClF2N5O/c20-13-3-2-12(8-16(13)23)19-26-25-17-9-24-10-18(27(17)19)28-6-5-11-1-4-14(21)15(22)7-11/h1-4,7-10H,5-6,23H2
UUAZLIWHOSTWRP-UHFFFAOYSA-N
40.0450.045
95
OSM-S-549MK067-1MMV1580434FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=CC(N)=C4)N32)=CC=C1F
InChI=1S/C19H15F2N5O/c20-15-5-4-12(8-16(15)21)6-7-27-18-11-23-10-17-24-25-19(26(17)18)13-2-1-3-14(22)9-13/h1-5,8-11H,6-7,22H2
CQZOPOXKTPBXOH-UHFFFAOYSA-N
42.82.8
96
OSM-S-550MK068-1MMV1580435FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(CC)C=C4)N23)=CC=C1F
InChI=1S/C21H18F2N4O/c1-2-14-3-6-16(7-4-14)21-26-25-19-12-24-13-20(27(19)21)28-10-9-15-5-8-17(22)18(23)11-15/h3-8,11-13H,2,9-10H2,1H3
GYRZMHSUHLZDJA-UHFFFAOYSA-N
40.1440.144
97
OSM-S-551MK069-1MMV1580436FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C(C(O)=O)C=C4)N32)=CC=C1F
InChI=1S/C20H14F2N4O3/c21-15-6-1-12(9-16(15)22)7-8-29-18-11-23-10-17-24-25-19(26(17)18)13-2-4-14(5-3-13)20(27)28/h1-6,9-11H,7-8H2,(H,27,28)
UMTJNRMURJHRAT-UHFFFAOYSA-N
4>25#DIV/0!
98
OSM-S-552MK070-1, MK070-2MMV1580437FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=CC(C(O)=O)=C4)N32)=CC=C1F
InChI=1S/C20H14F2N4O3/c21-15-5-4-12(8-16(15)22)6-7-29-18-11-23-10-17-24-25-19(26(17)18)13-2-1-3-14(9-13)20(27)28/h1-5,8-11H,6-7H2,(H,27,28)
GYFXXYGBOJTVGJ-UHFFFAOYSA-N
4>25#DIV/0!
99
OSM-S-553MK053-1MMV1580438FC1=CC(CCOC2=CN=CC3=NN=C(C4=CC=C([N+]([O-])=O)C=C4)N32)=CC=C1F
InChI=1S/C19H13F2N5O3/c20-15-6-1-12(9-16(15)21)7-8-29-18-11-22-10-17-23-24-19(25(17)18)13-2-4-14(5-3-13)26(27)28/h1-6,9-11H,7-8H2
ANXKNNLWLQBISN-UHFFFAOYSA-N
40.980.98
100
OSM-S-557MK074-1MMV1580439OCC(COC1=CN=CC2=NN=C(C3=CC=C4C(NC=C4)=C3)N21)C5=CC=CC=C5
InChI=1S/C22H19N5O2/c28-13-18(15-4-2-1-3-5-15)14-29-21-12-23-11-20-25-26-22(27(20)21)17-7-6-16-8-9-24-19(16)10-17/h1-12,18,24,28H,13-14H2
XPFWGOXNOABZNA-UHFFFAOYSA-N
40.0690.069
Loading...
Main menu