Excel statistics LMR-relapse study 25 - statistics.xlsx

	A	B	C	D	E	F	G	H	I	J	K	L	M	N	O	P	Q	R	S	T	U	V	W	X	Y	Z	AA	AB	AC	AD	AE	AF	AG	AH	AI	AJ	AK
1	Patient ID	Gender	Breed	Age at diagnosis (years)	Monocyte count at initiation of chemotherapy (T0)	RR	Lymphocyte count at initiation of chemotherapt (T0)	RR	LMR (T0)	Immunophenotype	Prednisolone	Monocyte count after first cycle chemo (T1)	RR	Lymphocyte count after first cycle chemo (T1)	RR	LMR ratio T1	Monocyte count after 2nd cycle chemo (T2)	RR	Lymphocyte count after 2nd cycle chemo (T2)	RR	LMR ratio (T2)	Start remission (days)	Time to relapse (DFI) (days)	Total time remission (days)	Monocyte count on relapse (T3)	RR	Lymphocyte count at relapse (T3)	RR	LMR ratio (T3)	Chemotherapy after relapse	Overall survival (days)	OS for censored data (days)	OS (all patients)	Time from relapse to survival time (OSr)	Time from relapse to last contact (OSr censored data)	OSr (all patients)	Reasons of death
2	1-12303	FN	Border Collie	11	0,58	0.0-1.3	0,49	1.0-4.8	0,8448275862	flow cytometry B cell	yes	0,61	0.0-1.3	1,01	1.0-4.8	1,655737705	1,32	0.0-1.3	1,26	1.0-4.8	0,9545454545	21	141	120	0,48	0.0-1.3	0,63	1.0-4.8	1,3125	LOMUSTINE	300		300	159		159	euthanasia, disease progression
3	1-18052	MN	Cross breed medium	2	1,5	0.0-1.3	7,82	1.0-4.8	5,213333333	flow cytometry B cell	yes	1,47	0.0-1.3	4,62	1.0-4.8	3,142857143	0,13	0.0-1.3	3,82	1.0-4.8	29,38461538	14	181	167	1,3	0.0-1.3	3,9	1.0 -4.8	3	LOMUSTINE	191		191	10		10	euthanasia, chemo side effects
4	1-66 74	MN	Boxer	5	0,83	0.0-1.3	0,33	1.0-4.8	0,3975903614	flow cytometry B cell	no	0,69	0.0-1.3	0,55	1.0-4.8	0,7971014493	0,76	0.0-1.3	0,62	1.0-4.8	0,8157894737	7	337	330	0,23	0.0-1.3	1,03	1.0-4.8	4,47826087	CEOP	1995		1995	1658		1658	euthanasia, disease progression
5	1-10646	MN	Labrador Retriever	10	1,14	0.0-1.3	9,00	1.0-4.8	7,894736842	immunocytochemistry B cell	yes	0,77	0.0-1.3	1,78	1.0-4.8	2,311688312	0,32	0.0-1.3	1,82	1.0-4.8	5,6875	7	221	214	0,49	0.13-1.15	1,13	1.06-4.95	2,306122449	CEOP	300		300	79		79	euthanasia, disease progression
6	1-18016	FN	West Highland White Terrier	14	0,3	0.0-1.3	2,40	1.0-4.8	8	immunohistochemistry B cell	yes	1,27	0.0-1.3	2,54	1.0-4.8	2	1,05	0.0-1.3	3,19	1.0-4.8	3,038095238	21	267	246	0,32	0.0-1.3	1,91	1.0-4.8	5,96875	CEOP	635		635	368		368	euthanasia, disease progression
7	1-10949	MN	Hungarian Vizsla	12	0,36	0.0-1.3	0,74	1.0-4.8	2,055555556	PARR clonal B cell	yes	0,09	0.0-1.3	2,12	1.0-4.8	23,55555556	0,42	0.0-1.3	0,49	1.0-4.9	1,166666667	7	144	137	0,3	0.0-1.3	0,47	1.0-4.8	1,566666667	LOMUSTINE	lost on followup	235	235		91	91
8	1-76 69	MN	Staffordshire BullTerrier	8	1,49	0.0-1.3	3,26	1.0-4.8	2,187919463	PARR clonal B cell	yes	0,04	0.0-1.3	3,17	1.0-4.8	79,25	0,09	0.0-1.3	2,81	1.0-4.10	31,22222222	21	107	86	2,16	0.0-1.3	2,18	1.0-4.8	1,009259259	LOMUSTINE	155		155	48		48	euthanasia, chemo side effects
9	1-11654	MN	Border Collie	8	0,91	0.0-1.3	1,77	1.0-4.8	1,945054945	PARR clonal B cell	yes	1	0.3-2.0	1	1.0-4.8	1	1,08	0,3-2,00	1,19	1.0-4.11	1,101851852	14	228	214	0,47	0.0-1.3	0,74	1.0-4.8	1,574468085	LOMUSTINE	760		760	532		532	euthanasia, disease progression
10	1-18519	FN	French Bulldog	6	0,39	0.0-1.3	0,50	1.0-4.8	1,282051282	immunocytochemistry B cell	yes	0,83	0.0-1.3	2,06	1.0-4.8	2,481927711	0,51	0.0-1.3	1	1.0-4.12	1,960784314	28	148	120	0,51	0.16-1.12	0,88	1.05-5.10	1,725490196	LOMUSTINE	lost on followup	176	176		28	28
11	1-20421	MN	Jack Russel Terrier	12	0,17	0.0-1.3	5,73	1.0-4.8	33,70588235	immunocytochemistry B cell	no	1,15	0.0-1.3	1,62	1.0-4.8	1,408695652	1,96	0.0-1.3	2,92	1.0-4.13	1,489795918	21	139	118	1,6	0.0-1.3	1,83	1.0-4.8	1,14375	DMAC	450		450	311		311	euthanasia, disease progression
12	1-19577	FN	Labrador retriever	7	0,43	0.0-1.3	1,57	1.0-4.8	3,651162791	PARR clonal B cell	yes	0,13	0.0-1.3	1,68	1.0-4.8	12,92307692	0,56	0.0-1.3	1,97	1.0-4.14	3,517857143	28	333	305	0,5	0.0-1.3	2,38	1.0-4.8	4,76	CEOP	lost on followup	458	458		125	125
13	1-22329	FN	Yorkshire Terrier	13	0,09	0.0-1.3	1,46	1.0-4.8	16,22222222	immunohistochemistry B cell	no	1,14	0.0-1.3	2,13	1.0-4.8	1,868421053	1,48	0.0-1.3	1,85	1.0-4.15	1,25	21	299	278	0,76	0.0-1.3	1,7	1.0-4.8	2,236842105	CEOP	lost on followup	420	420		121	121
14	1-22773	MN	Cockapoo	4	0,32	0.0-1.3	5,92	1.0-4.8	18,5	immunocytochemistry B cell	no	0,46	0.0-1.3	4,43	1.0-4.8	9,630434783	0,55	0.0-1.3	2,86	1.0-4.16	5,2	28	224	196	0,25	0.0-1.3	3,8	1.0-4.8	15,2	CEOP	lost on followup	395	395		171	171
15	1-25182	FN	Collie	8	0,84	0.0-1.3	1,45	1.0-4.8	1,726190476	immunocytochemistry B cell	no	0,72	0.0-1.3	1,45	1.0-4.8	2,013888889	0,68	0.0-1.3	1,45	1.0-4.17	2,132352941	21	184	163	0,21	0.0-1.3	1,32	1.0-4.8	6,285714286	DMAC	315		315	131		131	euthanasia, disease progression
16	1-25734	FN	Jack Russel Terrier	9	1,84	0.0-1.3	4,46	1.0-4.8	2,423913043	immunocytochemistry B cell	no	1,29	0.0-1.3	3,43	1.0-4.8	2,658914729	0,4	0.0-1.3	2,1	1.0-4.18	5,25	28	244	216	0,5	0.0-1.3	1,8	1.0-4.8	3,6	CEOP		790	790		546	546
17	1-26607	FN	old tyme bulldog	6	1,1	0.0-1.3	1,67	1.0-4.8	1,518181818	immunocytochemistry B cell	yes	0,84	0.0-1.3	2,65	1.0-4.8	3,154761905	0,95	0.0-1.3	2,69	1.0-4.19	2,831578947	28	103	75	0,59	0.0-1.3	1,89	1.0-4.8	3,203389831	EPIRRUBICIN SINGLE AGENT	lost on followup	116	116		13	13
18	1-26820	MN	Beagle	7	0,55	0.0-1.3	2,80	1.0-4.8	5,090909091	immunohistochemistry B cell	no	0,18	0.0-1.3	2,87	1.0-4.8	15,94444444	0,39	0.0-1.3	2,52	1.0-4.20	6,461538462	7	342	335	0,46	0.0-1.3	1,336	1.0-4.8	2,904347826	CEOP	lost on followup	815	815		473	473
19	1-22091	MN	German H pointer	6	0,2	0.0-1.3	0,36	1.0-4.8	1,8	PARR B cell	no	0,27	0.0-1.3	0,74	1.0-4.8	2,740740741	0,47	0.0-1.3	0,83	1.0-4.21	1,765957447	49	244	195	0,2	0.0-1.3	1,2	1.0-4.8	6	CEOP	852		852	608		608	euthanasia, disease progression
20	1-27369	MN	Australian Labradoodle	10	2,58	0.0-1.3	1,07	1.0-4.8	0,4147286822	immunocytochemistry B cell	no	1,22	0.0-1.3	2,16	1.0-4.8	1,770491803	0,72	0.0-1.3	1,96	1.0-4.22	2,722222222	21	370	349	1,04	0.0-1.3	1,51	1.0-4.8	1,451923077	CEOP	640		640	270		270	thyroid carcinoma
21	1-29171	FN	irish terrier	13	0,43	0.0-1.3	0,54	1.0-4.8	1,255813953	PARR clonal B cell	no	1,03	0.0-1.3	1,5	1.0-4.8	1,45631068	0,2	0.0-1.3	1	1.0-4.23	5	35	132	97	0,04	0.0-1.3	0,53	1.0-4.8	13,25	EPIRRUBICIN SINGLE AGENT	183		183	51		51	euthanasia, chemo side effects
22	1-30221	FN	medium cross	7	0,22	0.0-1.3	0,66	1.0-4.8	3	immunocytochemistry B cell	no	0,62	0.0-1.3	1,51	1.0-4.8	2,435483871	0,3	0,14-0,71	0,86	1.0-4.24	2,866666667	28	184	156	1,9	0,1-0,8	1,2	0,4-4,5	0,6315789474	CEOP		184	184		0	0
23	1-29056	MN	german shepherdxcollie	12	0,66	0.0-1.3	2,41	1.0-4.8	3,651515152	immunocytochemistry B cell	no	0,85	0.0-1.3	2,05	1.0-4.8	2,411764706	0,84	0.0-1.3	0,84	1.0-4.25	1	28	218	190	0,61	0.0-1.3	1,1	1.0-4.8	1,803278689	CEOP	lost on followup	335	335		117	117
24	44645	MN	Springer Spaniel	10	8,39	0.16-1.12	9,34	1.05-5.1	1,113230036	flow cytometry B cell	yes	1,76	0.16-1.12	0,81	1.05-5.1	0,4602272727	1,16	0.16-1.12	1,87	1.0-4.26	1,612068966	61	187	126	0,98	0.16-1.12	1,52	1.05-5.1	1,551020408	CEOP	Lost on follow up	752	752		565	565
25	50986	FN	Border Collie	8	1,12	0.16-1.12	1,15	1.05-5.1	1,026785714	flow cytometry B cell	yes	1,13	0.16-1.12	1,52	1.05-5.1	1,345132743	0,69	0.16-1.12	1,7	1.0-4.27	2,463768116	24	290	266	0,41	0.16-1.12	1,2	1.05-5.1	2,926829268	CEOP	Currently alive	812	812		522	522
26	45801	MN	Labradoodle	10	0,72	0.2-1.4	0,72	1.0-4.8	1	flow cytometry B cell	yes	0,58	0.16-1.12	0,9	1.05-5.1	1,551724138	0,91	0.16-1.12	1,07	1.0-4.28	1,175824176	38	551	513	0,35	0.16-1.12	1,17	1.05-5.1	3,342857143	CEOP	Lost on follow up	960	960		409	409
27	55129	FN	French Bulldog	3	1,25	0.16-1.12	1,63	1.05-5.1	1,304	flow cytometry B cell	yes	0,48	0.16-1.12	1,35	1.05-5.1	2,8125	0,62	0.16-1.12	2,09	1.0-4.29	3,370967742	22	309	287	0,53	0.16-1.12	1,01	1.05-5.1	1,905660377	CEOP	Currently alive - ongoing 2nd CEOP	446	446		137	137
28	56247	MN	Border Collie	11	8,51	0.16-1.12	1,94	1.05-5.1	0,2279670975	flow cytometry B cell	yes	0,51	0.16-1.12	1,12	1.05-5.1	2,196078431	0,73	0.16-1.12	1,24	1.0-4.30	1,698630137	15	283	268	22,57	0.16-1.12	7,79	1.05-5.1	0,3451484271	CEOP	Currently alive - ongoing 2nd CEOP	368	368		85	85
29	50605	MN	Tibetan Terrier	3	3,57	0.16-1.12	3,32	1.05-5.1	0,9299719888	immunocytochemistry B cell	yes	0,62	0.16-1.12	2,12	1.05-5.1	3,419354839	1,17	0.16-1.12	3,46	1.0-4.31	2,957264957	43	290	247	1,36	0.16-1.12	2,08	1.05-5.1	1,529411765	CEOP	740		740	450		450	cardiac arrest, either progression of lymphoma or aspiration pneumonia
30	53462	MN	Maltese x Shih Tzu	7	1,27	0.16-1.12	4,81	1.05-5.1	3,787401575	flow cytometry B cell	yes	0,74	0.16-1.12	1,96	1.05-5.1	2,648648649	0,71	0.16-1.12	1,64	1.0-4.32	2,309859155	46	285	239	0,44	0.16-1.12	1,59	1.05-5.1	3,613636364	CEOP	Currently alive - ongoing CEOP	589	589		304	304
31	33989	FN	Cairn Terrier	9	1,71	0.16-1.12	2,26	1.05-5.1	1,321637427	flow cytometry B cell	yes	1,33	0.16-1.12	2,4	1.05-5.1	1,804511278	1,57	0.16-1.12	3,47	1.0-4.33	2,210191083	36	296	260	1,38	0.16-1.12	1,67	1.05-5.1	1,210144928	CEOP	Lost on follow up	595	595		299	299
32	29339	ME	Labrador Retriever	7	0,63	0.0-1.6	2,09	0.8-4.7	3,317460317	PARR clonal B cell	yes	0,84	0.16-1.12	0,77	1.05-5.1	0,9166666667	0,82	0.16-1.12	1,21	1.0-4.34	1,475609756	21	452	431	0,87	0.16-1.12	1,58	1.05-5.1	1,816091954	CEOP	760		760	308		308	euthanasia, either for side effects chemo - diarrea, or
33	40137	MN	Bull Terrier	10	3,6	0.16-1.12	2,49	1.05-5.1	0,6916666667	flow cytometry B cell	yes	2,16	0.16-1.12	2,8	1.05-5.1	1,296296296	2,06	0.16-1.12	2,92	1.0-4.35	1,417475728	9	333	324	6,92	0.16-1.12	4,36	1.05-5.1	0,6300578035	CEOP	Lost on follow up	703	703		370	370
34	40995	MN	Crossbreed	6	1,21	0.16-1.12	1,28	1.05-5.1	1,05785124	immunohistochemistry B cell	yes	1,47	0.16-1.12	1,55	1.05-5.1	1,054421769	1,39	0.16-1.12	1,37	1.0-4.36	0,9856115108	23	316	293	1,05	0.16-1.12	1,24	1.05-5.1	1,180952381	CEOP	Lost on follow up	518	518		202	202
35	41923	MN	Crossbreed	4	0,6	0.16-1.12	1,62	1.05-5.1	2,7	flow cytometry B cell	yes	0,57	0.16-1.12	1,38	1.05-5.1	2,421052632	0,51	0.16-1.12	1,65	1.0-4.37	3,235294118	29	652	623	0,29	0.16-1.12	0,86	1.05-5.1	2,965517241	LOMUSTINE	870		870	218		218	euthanasia, disease progression
36	44646	MN	Cavapoo	11	15,45	0.16-1.12	4,23	1.05-5.1	0,2737864078	immunocytochemistry B cell	yes	1,58	0.16-1.12	2,95	1.05-5.1	1,867088608	0,74	0.16-1.12	3,21	1.0-4.38	4,337837838	35	241	206	0,82	0.16-1.12	1,01	1.05-5.1	1,231707317	CEOP	403		403	162		162	euthanasia, disease progression
37	44965	FN	Shar-pei	5	35,88	0.16-1.12	21,76	1.05-5.1	0,6064659978	immunocytochemistry B cell	yes	0,68	0.16-1.12	1,73	1.05-5.1	2,544117647	0,45	0.16-1.12	2,16	1.0-4.39	4,8	50	200	150	0,24	0.16-1.12	1,29	1.05-5.1	5,375	LOMUSTINE	417		417	217		217	euthanasia, disease progression
38	45720	FN	Staffordshire Bull Terrier	5	0,51	0.16-1.12	0,95	1.05-5.1	1,862745098	flow cytometry B cell	yes	0,37	0.16-1.12	1,1	1.05-5.1	2,972972973	0,53	0.16-1.12	1,29	1.0-4.40	2,433962264	22	239	217	0,33	0.16-1.12	1	1.05-5.1	3,03030303	LOMUSTINE	368		368	129		129	euthanasia, disease progression
39	46774	MN	Border Collie	10	1,1	0.0-1.6	1,44	0.8-4.7	1,309090909	flow cytometry B cell	yes	1,03	0.16-1.12	1,1	1.05-5.1	1,067961165	1,32	0.16-1.12	1,35	1.0-4.41	1,022727273	43	223	180	0,7	0.16-1.12	0,76	1.05-5.1	1,085714286	LOMUSTINE	272		272	49		49	euthanasia, disease progression
40	46846	FN	Border Collie	10	1,02	0.0-1.6	0,68	0.8-4.7	0,6666666667	immunocytochemistry B cell	yes	0,84	0.16-1.12	0,91	1.05-5.1	1,083333333	0,97	0.16-1.12	0,89	1.0-4.42	0,9175257732	36	248	212	0,48	0.16-1.12	0,76	1.05-5.1	1,583333333	CEOP	Lost on follow up	763	763		515	515
41	46811	MN	Jack Russel Terrier	13	0,27	0.0-1.6	0,72	0.8-4.7	2,666666667	flow cytometry B cell	yes	1,04	0.16-1.12	1,62	1.05-5.1	1,557692308	0,86	0.16-1.12	1,54	1.0-4.43	1,790697674	36	170	134	0,38	0.16-1.12	0,83	1.05-5.1	2,184210526	CHLORAMBUCIL SINGLE AGENT	352		352	182		182	euthanasia, disease progression
42	47334	MN	Crossbreed	8	2,16	0.16-1.12	1,09	1.05-5.1	0,5046296296	flow cytometry B cell	no	0,47	0.16-1.12	1,15	1.05-5.1	2,446808511	0,59	0.16-1.12	1,17	1.0-4.44	1,983050847	60	226	166	0,41	0.2-1.4	0,74	1.0-4.8	1,804878049	LOMUSTINE	325		325	99		99	euthanasia, disease progression
43	48657	ME	Border Collie	3	0,89	0.16-1.12	1,31	1.05-5.1	1,471910112	flow cytometry B cell	yes	0,7	0.16-1.12	1,22	1.05-5.1	1,742857143	0,85	0.16-1.12	1,56	1.0-4.45	1,835294118	22	218	196	1,53	0.16-1.12	1,57	1.05-5.1	1,026143791	LOMUSTINE	Lost on follow up	261	261		43	43
44	48405	MN	Tibetan Terrier	9	0,92	0.16-1.12	1,33	1.05-5.1	1,445652174	immunocytochemistry B cell	yes	1	0.16-1.12	1,57	1.05-5.1	1,57	0,69	0.16-1.12	1,48	1.0-4.46	2,144927536	50	155	105	0,44	0.16-1.12	1,61	1.05-5.1	3,659090909	PREDNISOLONE	Lost on follow up	168	168		13	13
45	55661	FN	Labrador Retriever	9	0,65	0.16-1.12	1,79	1.05-5.1	2,753846154	immunocytochemistry B cell	yes	0,43	0.16-1.12	1,88	1.05-5.1	4,372093023	0,75	0.16-1.12	2,33	1.0-4.47	3,106666667	36	156	120	0,29	0.16-1.12	2,05	1.05-5.1	7,068965517	LOMUSTINE	Lost on follow up	234	234		78	78
46	40747	MN	Labrador Retriever	11	0,41	0.2-1.4	4,40	1.0-4.8	10,73170732	flow cytometry B cell	yes	0,54	0.16-1.12	1,47	1.05-5.1	2,722222222	1,42	0.16-1.12	1,45	1.0-4.48	1,021126761	71	229	158	1,59	0.16-1.12	2,79	1.05-5.1	1,754716981	PREDNISOLONE	Lost on follow up	232	232		3	3
47	44280	MN	Australian Kelpie	5	1,2	0.16-1.12	1,25	1.05-5.1	1,041666667	flow cytometry B cell	yes	1,17	0.16-1.12	1,25	1.05-5.1	1,068376068	0,69	0.16-1.12	0,79	1.0-4.49	1,144927536	36	343	307	6,57	0.16-1.12	1,81	1.05-5.1	0,2754946728	CEOP	Lost on follow up	602	602		259	259
48	41444	FN	Jack Russel Terrier	10	0,57	0.2-1.4	0,43	1.0-4.8	0,7543859649	flow cytometry B cell	yes	0,99	0.16-1.12	3,68	1.05-5.1	3,717171717	1,06	0.16-1.12	2,47	1.0-4.50	2,330188679	64	164	100	1,12	0.16-1.12	3,99	1.05-5.1	3,5625	LOMUSTINE	531		531	367		367	euthanasia, disease progression
49	49501	ME	Golden Retriever	6	1,63	0.16-1.12	2,28	1.05-5.1	1,398773006	flow cytometry B cell	yes	0,5	0.16-1.12	1,37	1.05-5.1	2,74	0,57	0.16-1.12	2,13	1.0-4.51	3,736842105	63	106	43	0,54	0.16-1.12	1,51	1.05-5.1	2,796296296	LOMUSTINE	223		223	117		117	euthanasia, neuro signs, likely disease progression
50	42716	FN	Cocker Spaniel	11	1	0.16-1.12	0,76	1.05-5.1	0,76	immunocytochemistry B cell	yes	0,8	0.16-1.12	0,86	1.05-5.1	1,075	0,96	0.16-1.12	1,3	1.0-4.52	1,354166667	22	358	336	1,41	0.0-1.6	1,1	0.8-4.7	0,780141844	CEOP	413		413	55		55	euthanasia, disease progression
51	1-31446	FN	bernese mountain	6	0,91	0,14-0,71	2,35	0,99-3,83	2,582417582	immunocytochemistry B cell	no	0,81	0,14-0,71	3,67	0,99-3,83	4,530864198	0,88	0.14-0.71	3,5	1.0-4.53	3,977272727	28	201	173	0,35	0.14-0.71	1,48	0.99-3.83	4,228571429	CEOP	currently alive - on CEOP	370	370		169	169
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100