GiveWell, Analysis of baseline mortality for Imdad et al. 2017 trials for VAS CEA (public)

	A	B	C	D	E	F	G	H	I	J	K	L	M	N	O	P	Q	R	S	T	U
1		Study name:	Overall	Agarwal 1995	Barreto 1994	Benn 1997	Chowdhury 2002	Daulaire 1992	DEVTA trial 2013	Dibley 1996	Donnen 1998	Fisker 2014	Herrera 1992	Pant 1996	Rahmathullah 1990	Ross 1993 HEALTH	Ross 1993 SURVIVAL	Sommer 1986	Venkatarao 1996	Vijayaraghavan 1990	West 1991
2		Location:		India	Bahia	Guinea-Bissau	India	Nepal	India	Central Java	Democratic Republic of the Congo	Guinea-Bissau	Sudan	Nepal	India	Ghana	Ghana	Aceh	India	India	Nepal

3		Date conducted:	-	1990.5	1990.5	1994	1998	1989	2001.5	1990.5	1992	2009	1989	1991	1986	1990.5	1990	1983	1992	1988	1989.5
4		Weight in Imdad et a. 2017 analysis 1.1, random-effects model	-	4.00%	0.50%	1.40%	0.90%	8.90%	13.60%	0.20%	2.00%	7.90%	9.80%	6.20%	6.30%	2.10%	11.50%	8.70%	1.10%	4.30%	10.50%
5		Year (for this analysis):	-	1990	1990	1994	1998	1990	2001	1990	1992	2009	1990	1991	1990	1990	1990	1990	1992	1990	1990
6	Global Burden of Disease (GBD) 2019 data, All causes
7	All causes	Number of under-5 deaths (per year)	-	2,841,976	31,594	9,554	2,841,976	109,450	2,841,976	40,954	300,498	9,554	144,096	109,450	2,841,976	73,040	73,040	7,925	2,841,976	2,841,976	109,450
8	All causes	Number of "Early neonatal" (0-6 days) deaths (per year)	-	887,054	7,423	1,923	887,054	31,548	887,054	12,292	51,704	1,923	34,572	31,548	887,054	18,198	18,198	2,083	887,054	887,054	31,548
9	All causes	Number of "Late neonatal" (7-27 days) deaths (per year)	-	361,559	2,126	734	361,559	14,897	361,559	4,920	17,905	734	14,754	14,897	361,559	5,434	5,434	924	361,559	361,559	14,897
10	All causes	Number of "Post neonatal" (28-364 days) deaths (per year)	-	712,842	18,081	2,378	712,842	30,549	712,842	13,650	107,516	2,378	42,342	30,549	712,842	17,847	17,847	2,803	712,842	712,842	30,549
11	All causes	Mortality rate in each month of life for 1-5 month olds compared to 6-11 month olds	-	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0
12	All causes	Number of annual deaths in post-neonatal period in each monthly age bracket	-	64,804	1,644	216	64,804	2,777	64,804	1,241	9,774	216	3,849	2,777	64,804	1,622	1,622	255	64,804	64,804	2,777
13	All causes	Number of deaths in 1-5 month olds (per year)	-	324,019	8,219	1,081	324,019	13,886	324,019	6,205	48,871	1,081	19,246	13,886	324,019	8,112	8,112	1,274	324,019	324,019	13,886
14	All causes	Number of remaining deaths in 6-59 months olds (per year)	-	1,269,343	13,826	5,816	1,269,343	49,120	1,269,343	17,537	182,019	5,816	75,524	49,120	1,269,343	41,295	41,295	3,644	1,269,343	1,269,343	49,120
15	Global Burden of Disease (GBD) 2019 data, Measles
16	Measles	Number of under-5 deaths (per year)	-	135,688	2	1,570	135,688	8,325	135,688	2,817	18,218	1,570	21,699	8,325	135,688	4,995	4,995	316	135,688	135,688	8,325
17	Measles	Number of "Early neonatal" (0-6 days) deaths (per year)	-	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
18	Measles	Number of "Late neonatal" (7-27 days) deaths (per year)	-	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
19	Measles	Number of "Post neonatal" (28-364 days) deaths (per year)	-	33,006	1	432	33,006	2,544	33,006	785	6,045	432	6,963	2,544	33,006	1,338	1,338	83	33,006	33,006	2,544
20	Measles	Mortality rate in each month of life for 1-5 month olds compared to 6-11 month olds	-	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0
21	Measles	Number of annual deaths in post-neonatal period in each monthly age bracket	-	3,001	0	39	3,001	231	3,001	71	550	39	633	231	3,001	122	122	8	3,001	3,001	231
22	Measles	Number of deaths in 1-5 month olds (per year)	-	15,003	1	197	15,003	1,156	15,003	357	2,748	197	3,165	1,156	15,003	608	608	38	15,003	15,003	1,156
23	Measles	Number of remaining deaths in 6-59 months olds (per year)	-	120,685	1	1,373	120,685	7,168	120,685	2,460	15,471	1,373	18,534	7,168	120,685	4,387	4,387	278	120,685	120,685	7,168
24	Global Burden of Disease (GBD) 2019 data, Diarrheal diseases
25	Diarrheal diseases	Number of under-5 deaths (per year)	-	370,585	6,889	1,363	370,585	14,334	370,585	6,196	26,473	1,363	22,290	14,334	370,585	21,934	21,934	1,058	370,585	370,585	14,334
26	Diarrheal diseases	Number of "Early neonatal" (0-6 days) deaths (per year)	-	26,864	45	35	26,864	780	26,864	192	700	35	2,188	780	26,864	3,391	3,391	25	26,864	26,864	780
27	Diarrheal diseases	Number of "Late neonatal" (7-27 days) deaths (per year)	-	37,787	230	82	37,787	1,187	37,787	667	1,498	82	2,712	1,187	37,787	1,574	1,574	100	37,787	37,787	1,187
28	Diarrheal diseases	Number of "Post neonatal" (28-364 days) deaths (per year)	-	156,371	5,916	545	156,371	6,764	156,371	3,663	15,081	545	10,456	6,764	156,371	6,803	6,803	628	156,371	156,371	6,764
29	Diarrheal diseases	Mortality rate in each month of life for 1-5 month olds compared to 6-11 month olds	-	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0
30	Diarrheal diseases	Number of annual deaths in post-neonatal period in each monthly age bracket	-	14,216	538	50	14,216	615	14,216	333	1,371	50	951	615	14,216	618	618	57	14,216	14,216	615
31	Diarrheal diseases	Number of deaths in 1-5 month olds (per year)	-	71,078	2,689	248	71,078	3,074	71,078	1,665	6,855	248	4,753	3,074	71,078	3,092	3,092	285	71,078	71,078	3,074
32	Diarrheal diseases	Number of remaining deaths in 6-59 months olds (per year)	-	234,857	3,925	998	234,857	9,292	234,857	3,671	17,420	998	12,637	9,292	234,857	13,878	13,878	648	234,857	234,857	9,292
33	Global Burden of Disease (GBD) 2019 data, Communicable, maternal, neonatal, and nutritional diseases
34	Communicable, maternal, neonatal, and nutritional diseases	Number of under-5 deaths (per year)	-	2,558,388	24,458	8,534	2,558,388	99,627	2,558,388	33,618	264,938	8,534	110,404	99,627	2,558,388	67,454	67,454	6,109	2,558,388	2,558,388	99,627
35	Communicable, maternal, neonatal, and nutritional diseases	Number of "Early neonatal" (0-6 days) deaths (per year)	-	829,476	6,422	1,807	829,476	29,621	829,476	10,684	47,381	1,807	28,741	29,621	829,476	17,301	17,301	1,804	829,476	829,476	29,621
36	Communicable, maternal, neonatal, and nutritional diseases	Number of "Late neonatal" (7-27 days) deaths (per year)	-	334,467	1,766	671	334,467	13,984	334,467	4,034	16,155	671	11,871	13,984	334,467	5,102	5,102	716	334,467	334,467	13,984
37	Communicable, maternal, neonatal, and nutritional diseases	Number of "Post neonatal" (28-364 days) deaths (per year)	-	642,445	13,978	2,135	642,445	27,882	642,445	11,235	96,375	2,135	32,868	27,882	642,445	16,453	16,453	2,150	642,445	642,445	27,882
38	Communicable, maternal, neonatal, and nutritional diseases	Mortality rate in each month of life for 1-5 month olds compared to 6-11 month olds	-	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0
39	Communicable, maternal, neonatal, and nutritional diseases	Number of annual deaths in post-neonatal period in each monthly age bracket	-	58,404	1,271	194	58,404	2,535	58,404	1,021	8,761	194	2,988	2,535	58,404	1,496	1,496	195	58,404	58,404	2,535
40	Communicable, maternal, neonatal, and nutritional diseases	Number of deaths in 1-5 month olds (per year)	-	292,020	6,354	970	292,020	12,674	292,020	5,107	43,807	970	14,940	12,674	292,020	7,479	7,479	977	292,020	292,020	12,674
41	Communicable, maternal, neonatal, and nutritional diseases	Number of remaining deaths in 6-59 months olds (per year)	-	1,102,425	9,917	5,085	1,102,425	43,347	1,102,425	13,793	157,595	5,085	54,851	43,347	1,102,425	37,572	37,572	2,611	1,102,425	1,102,425	43,347
42	Global Burden of Disease (GBD) 2019 data, Maternal and neonatal disorders
43	Maternal and neonatal disorders	Number of under-5 deaths (per year)	-	852,761	9,413	1,888	852,761	25,212	852,761	12,011	43,364	1,888	37,727	25,212	852,761	14,951	14,951	2,094	852,761	852,761	25,212
44	Maternal and neonatal disorders	Number of "Early neonatal" (0-6 days) deaths (per year)	-	677,242	6,237	1,486	677,242	20,413	677,242	9,473	36,674	1,486	24,922	20,413	677,242	12,603	12,603	1,629	677,242	677,242	20,413
45	Maternal and neonatal disorders	Number of "Late neonatal" (7-27 days) deaths (per year)	-	152,075	1,298	335	152,075	4,222	152,075	1,980	4,663	335	7,574	4,222	152,075	1,920	1,920	368	152,075	152,075	4,222
46	Maternal and neonatal disorders	Number of "Post neonatal" (28-364 days) deaths (per year)	-	21,037	1,855	55	21,037	518	21,037	521	1,826	55	4,438	518	21,037	371	371	91	21,037	21,037	518
47	Maternal and neonatal disorders	Mortality rate in each month of life for 1-5 month olds compared to 6-11 month olds	-	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0
48	Maternal and neonatal disorders	Number of annual deaths in post-neonatal period in each monthly age bracket	-	1,912	169	5	1,912	47	1,912	47	166	5	403	47	1,912	34	34	8	1,912	1,912	47
49	Maternal and neonatal disorders	Number of deaths in 1-5 month olds (per year)	-	9,562	843	25	9,562	236	9,562	237	830	25	2,017	236	9,562	169	169	41	9,562	9,562	236
50	Maternal and neonatal disorders	Number of remaining deaths in 6-59 months olds (per year)	-	13,881	1,035	42	13,881	341	13,881	321	1,197	42	3,213	341	13,881	259	259	55	13,881	13,881	341
51	Global Burden of Disease (GBD) 2019 data, Nutritional deficiencies
52	Nutritional deficiencies	Number of under-5 deaths (per year)	-	190,524	2,124	429	190,524	6,529	190,524	674	12,168	429	3,319	6,529	190,524	3,162	3,162	264	190,524	190,524	6,529
53	Nutritional deficiencies	Number of "Early neonatal" (0-6 days) deaths (per year)	-	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
54	Nutritional deficiencies	Number of "Late neonatal" (7-27 days) deaths (per year)	-	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
55	Nutritional deficiencies	Number of "Post neonatal" (28-364 days) deaths (per year)	-	98,637	1,790	119	98,637	3,407	98,637	400	6,416	119	1,585	3,407	98,637	993	993	133	98,637	98,637	3,407
56	Nutritional deficiencies	Mortality rate in each month of life for 1-5 month olds compared to 6-11 month olds	-	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0
57	Nutritional deficiencies	Number of annual deaths in post-neonatal period in each monthly age bracket	-	8,967	163	11	8,967	310	8,967	36	583	11	144	310	8,967	90	90	12	8,967	8,967	310
58	Nutritional deficiencies	Number of deaths in 1-5 month olds (per year)	-	44,835	813	54	44,835	1,549	44,835	182	2,916	54	720	1,549	44,835	451	451	60	44,835	44,835	1,549
59	Nutritional deficiencies	Number of remaining deaths in 6-59 months olds (per year)	-	145,689	1,310	375	145,689	4,981	145,689	492	9,252	375	2,599	4,981	145,689	2,711	2,711	203	145,689	145,689	4,981
60	Global Burden of Disease (GBD) 2019 data, Other infectious diseases
61		Number of under-5 deaths (per year)	-	1,008,829	6,030	3,284	1,008,829	45,227	1,008,829	11,921	164,714	3,284	25,369	45,227	1,008,829	22,411	22,411	2,378	1,008,829	1,008,829	45,227
62		Number of "Early neonatal" (0-6 days) deaths (per year)	-	125,369	140	287	125,369	8,429	125,369	1,019	10,007	287	1,631	8,429	125,369	1,307	1,307	151	125,369	125,369	8,429
63		Number of "Late neonatal" (7-27 days) deaths (per year)	-	144,605	237	254	144,605	8,575	144,605	1,387	9,993	254	1,585	8,575	144,605	1,609	1,609	248	144,605	144,605	8,575
64		Number of "Post neonatal" (28-364 days) deaths (per year)	-	333,393	4,417	984	333,393	14,648	333,393	5,866	67,007	984	9,426	14,648	333,393	6,949	6,949	1,215	333,393	333,393	14,648
65		Mortality rate in each month of life for 1-5 month olds compared to 6-11 month olds	-	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0
66		Number of annual deaths in post-neonatal period in each monthly age bracket	-	30,308	402	89	30,308	1,332	30,308	533	6,092	89	857	1,332	30,308	632	632	110	30,308	30,308	1,332
67		Number of deaths in 1-5 month olds (per year)	-	151,542	2,008	447	151,542	6,658	151,542	2,666	30,458	447	4,285	6,658	151,542	3,159	3,159	552	151,542	151,542	6,658
68		Number of remaining deaths in 6-59 months olds (per year)	-	587,312	3,645	2,296	587,312	21,565	587,312	6,848	114,256	2,296	17,868	21,565	587,312	16,337	16,337	1,427	587,312	587,312	21,565
69	Final parameters for the CEA
70		Proportion of mortalities among 6-59-month-olds attributed to measles or diarrheal disease	34%	28%	28%	41%	28%	34%	28%	35%	18%	41%	41%	34%	28%	44%	44%	25%	28%	28%	34%
71		Proportion of mortalities among 6-59-month-olds attributed to other infectious diseases	41%	46%	26%	39%	46%	44%	46%	39%	63%	39%	24%	44%	46%	40%	40%	39%	46%	46%	44%
72		Proportion of mortalities among 6-59-month-olds attributed to any infectious disease (including measles or diarrheal disease)	75%
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