Age of donor at the time of sample collection. Specify the age unit (week, month, year) in age_unit.

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Age unit (week, month, year) for the age_value.

day; week; month; year

day; week; month; year

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genderidentity_selfreported

Donor self-reported gender identity.

Female Gender; Male Gender; Non-Binary Gender; Other Gender; Agender; Gender Fluid; Gender Identifier X; Genderqueer; Transgender; Two-spirit

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Body mass index of the donor at the time of collection.

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Height of donor in cm at the time of collection.

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Weight of donor in kilograms at the time of collection.

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ethnicity_selfreported_freetext

Donor self-reported ethnicity (or ethnicities) in free-text; can include tribe, dialect group, etc. If race information is submitted under this field, please ensure that the question(s) and response options posed to donors are included in the next metadata category (“ethnicity_question_text”). Separate multiple entries with a comma.

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ethnicity_question_text

Question and response options posed to donors for collecting metadata on donor self-reported ethnicity and / or tribe and / or dialect group and / or race etc.

“What is your ethnicity?”; “Are you Hispanic/Latino?”; Example from All of Us “Which categories describe you? Select all that apply. Note You may select more than one group. American Indian or Alaska Native (for example, Aztec, Blackfeet Tribe, Mayan, Navajo Nation, Native Village of Barrow (Utqiagvik) Inupiat Traditional Government, Nome Eskimo Community, etc.)* Asian (for example, Asian Indian, Chinese, Filipino, Japanese, Korean, Vietnamese, etc.)* Black, African American, or African (for example, African American, Ethiopian, Haitian, Jamaican, Nigerian, Somali, etc.)* Hispanic, Latino, or Spanish (for example, Columbian, Cuban, Dominican, Mexican or Mexican American, Puerto Rican, Salvadoran, etc.)* Middle Eastern or North African (for example, Algerian, Egyptian, Iranian, Lebanese, Moroccan, Syrian, etc.)* Native Hawaiian or other Pacific Islander (for example, Chamorro, Fijian, Marshallese, Native Hawaiian, Tongan, etc.)* White (for example, English, European, French, German, Irish, Italian, Polish, etc.)* None of these fully describe me (optional free text answer) Prefer not to answer” not collected, not available

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If the donor smokes/smoked or not.

active; former; never

active; former; never

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diet_meat_consumption

Dietary patterns of donor – meat (chicken, seafood, fish, pork, lamb, beef, etc.) consumption versus meat-free diet – at time of sample collection. Fill yes if donor consumes meat or no if donor does not consumes meat.

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language_donor_primary_language

Primary language(s), spoken by donor. Can include dialects (for example, Hokkien).

Mandarin Chinese; Hokkien; Bahasa Melayu; Tamil; Hausa; Yoruba; Swahili

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Current residence location country state

geography_currentresidence_location_country_state

Country and state of donor’s current residence at time of sample collection.

Singapore; United Kingdom; Massachusetts USA; New South Wales Australia; Bauchi State; Nigeria

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geography_currentresidence_location_granular

Nearest city, town, or village to location of donor’s current residence at time of sample collection.

Singapore; Cambridge; Boston; Kingston

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geography_collectionsite_latitude_longitude

Latitude and longitude GPS coordinates of collection site in decimal degrees. Please specify latitude followed by longitude separated with a comma.

1.3,103.8; not_sharable

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geography_currentresidence_duration

Duration of residence, in years, rounded up to the nearest whole number, at time of sample collection.

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geography_currentresidence_urbanrural

Urban, suburban, or rural descriptor of current residence.

urban; suburban; rural

urban; suburban; rural

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Place of birth location - country state

geography_placeofbirth_location_country_state

Country and state of place of birth.

Singapore; United Kingdom; Massachusetts USA; New South Wales Australia; Bauchi State; Nigeria

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geography_placeofbirth_location_granular

Nearest city, town, or village to location of place of birth.

Singapore; Cambridge; Boston; Kingston

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geography_placeofbirth_duration

Duration of residence, in years, rounded up to the nearest whole number.

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geography_placeofbirth_urbanrural

Urban, suburban, or rural descriptor of place of birth.

urban; suburban; rural

urban; suburban; rural

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ethnicity_parents_selfreported_freetext

Donor’s parents’ self-reported ethnicity (or ethnicities) in free-text; can include tribe, dialect group, etc. Separate multiple entries with a comma.

Singaporean Chinese; Singaporean Malay; Singaporean Indian; Haitian; Nigerian Hausa; Ghana Hausa; Benin Kanuri; Nigerian Kanuri; Igbo; Luo; Herero; Garifuna; Kalinago

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language_mother_father_tongue

Ancestral language(s), spoken by parents (“mother tongue” and / or “father tongue”) and / or grandparents. Can include dialects (for example, Hokkien).

Mandarin Chinese; Hokkien; Bahasa Melayu; Tamil; Hausa; Yoruba; Swahili

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Age at menarche, rounded to nearest whole number.

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reproductive_menopause

Menopausal status of donor at time of sample collection.

pre-menopausal; peri-menopausal; post-menopausal; post-menopausal (induced); not applicable

pre-menopausal; peri-menopausal; post-menopausal; post-menopausal (induced); not applicable

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reproductive_number_children

Number of children (full-term pregnancies) the donor has given birth to at time of sample collection.

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reproductive_number_pregnancies

Number of pregnancies the donor has had at time of sample collection.

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sample_collection_time_point

Time point when the sample was collected, indicated as YYYY/MM/DD. If this information is not sharable, please indiciate "not_shareable".

2022/10/29; not_shareable

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years_since_smoking_cessation

If smoking status is "former", specify the number of years since smoking cessation, if available.

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smoking_pack_years

Estimated number of packs (20 cigarettes) smoked per day multiplied by the number of years subject was smoking.

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comorbidities_ontology_term_id

Indicate all comorbidities/ secondary diagnoses of the donor (primary diagnosis was asked in disease_ontology_term_id field of tier 1 metadata). This must be a MONDO term. Separate multiple entries with a comma.

MONDO ontology term

MONDO:0005300; MONDO:0005240

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medication_within_last_month_pre_sample

Please indicate the last known therapy, as drug categories from the NCIT ontology, administered to the patient within the last month prior to sample collection. If this information is not shareable due to data privacy restrictions, please indiciate "not_shareable".

NCIT ontology term

NCIT:C389; NCIT:C71534; NCIT:C78113; not_shareable

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protocol_tissue_dissociation

The dissociation process that was used for the dissociation.

Collagenase D + DNAse; Dispase + collagenase; Cold protease 1h; Collagenase + Elastase + DNAse; Cold protease overnight; Collagenase A + DNAse; Mechanical dissociation (chilled) + detergent-based nuclei isolation; Mechanical dissociation (frozen) + citric-acid based nuclei isolation; other

Cold protease 1h; Collagenase + Elastase + DNAse; Mechanical dissociation (chilled) + detergent-based nuclei isolation

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Tissue dissociation protocol free text

protocol_tissue_dissociation_free_text

A free text option to describe dissociation process if not listed in available options.

Collagenase IV and I at 37°C for 8h

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bloodtest_creatinine

Serum creatinine level of donor at the time of sample collection.

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bloodtest_creatinine_unit

Serum creatinine unit.

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urine_albumin_creatinine_ratio

Spot urine albumin to creatinine ratio (uACR) of donor at the time of sample collection.

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urine_albumin_creatinine_ratio_unit

Unit of urine albumin to creatinine ratio.

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urine_protein_creatinine_ratio

Spot urine protein to creatinine ratio (uPCR) of donor at the time of sample collection.

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urine_protein_creatinine_ratio_unit

Unit of urine protein to creatinine ratio.

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glomerulal_filtration_rate

Glomerulal filtration rate of donor at the time of sample collection in mL/min/1.73 m2.

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urinetest_albuminuria_presence

Albumin presence in the urine (even microalbuminuria).

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bloodtest_anca_ab_presence

Anti-neutrophil cytoplasmic (ANCA) antibodies presence in the serum at the time of sample collection.

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bloodtest_ana_ab_presence

Antinuclear (ANA) antibodies presence in the serum at the time of sample collection.

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bloodtest_gbm_ab_presence

Anti-Glomerular Basement Membrane (anti-GBM) antibodies presence in the serum at the time of sample collection.

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immunocomplex_deposition

Immunocomplex deposition on electron microscopy.

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histo_iga_presence

IgA presence in kidney histopathology.

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histo_iga_distribution

IgA deposition patern on kidney histopathology.

glomeruli; subendothelial; subepithelial; mesangial; unknown

glomeruli; subendothelial; subepithelial; mesangial; unknown

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histo_igg_presence

IgG presence in kidney histopathology.

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histo_igg_distribution

IgG deposition patern on kidney histopathology.

glomeruli; subendothelial; subepithelial; mesangial; unknown

glomeruli; subendothelial; subepithelial; mesangial; unknown

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histo_igm_presence

IgM presence in kidney histopathology.

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histo_igm_distribution

IgM deposition patern on kidney histopathology.

glomeruli; subendothelial; subepithelial; mesangial; unknown

glomeruli; subendothelial; subepithelial; mesangial; unknown

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histo_c3_presence

C3 presence in kidney histopathology.

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histo_c3_distribution

C3 deposition patern on kidney histopathology.

glomeruli; subendothelial; subepithelial; mesangial; unknown

glomeruli; subendothelial; subepithelial; mesangial; unknown

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histo_c1q_presence

C1q presence in kidney histopathology.

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histo_c1q_distribution

C1q deposition patern on kidney histopathology.

glomeruli; subendothelial; subepithelial; mesangial; unknown

glomeruli; subendothelial; subepithelial; mesangial; unknown

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histo_glomerulosclerosis_percent

Sclerotic glomeruli percentage on histopathology.

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bloodtest_sodium

Serum sodium at the time of sample collection. Please fill in units value as well.

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bloodtest_sodium_unit

Serum sodium unit.

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bloodtest_bicarbonate

Serum bicarbonate (HCO3-) at the time of sample collection. Please fill in units value as well.

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bloodtest_bicarbonate_unit

Serum bicarbonate (HCO3-) unit

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bloodtest_potassium

Serum potassium in the last blood test of the donor before collection. Please fill in units value as well.

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bloodtest_potassium_unit

Serum potassium unit.

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