| A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | |
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1 | Deal Date | R&D | Client | Upfront Cash ($M) | Deal Size ($M) | Deal Subject | Deal Types | Exclusivity | Stage | Has Tags | Document Source | Disease | Indication | Technology | Sub-Technology | Territory | Sub-Territory | |||||||||
2 | 6/2015 | University of California, UC Davis | Sage Therapeutics | $0.110 | $2.800 | Allopregnanolone (neurosteroid) for use in seizures and traumatic brain injury | License | Exclusive | Preclinical | Yes | SEC Redacted | Central Nervous System | Other Central Nervous System, Spinal Cord Injury | Worldwide | ||||||||||||
3 | 6/2015 | University of Jerusalem, Yissum Research Development | Immune Pharmaceuticals | $0.030 | $4.930 | Topical nano-formulation of AmiKet for pain | License, Research | Exclusive | Formulation | Yes | SEC Full | Central Nervous System | Pain | Drug Delivery, Synthetics | Small Molecule, Topical | Worldwide | ||||||||||
4 | 6/2015 | University of South Florida | Cellular Biomedicine | $2.500 | $29.300 | CD40LGVAX vaccine and related technologies for lung cancer | License | Exclusive | Phase I | Press Release | Cancer | Lung | Vaccines | Worldwide | ||||||||||||
5 | 1/2015 | San Raffaele Telethon Institute For Gene Therapy | Biogen | $5.000 | Lentiviral gene transfer technology to develop gene therapies for hemophilia | License, Option, Research | Discovery | Press Release | Hematologic | Hemophilia | Oligonucleotides | Gene Therapy | Worldwide | |||||||||||||
6 | 12/2014 | Scripps Research Institute | Corvus | $0.110 | $2.700 | Mouse CD73 antibody for treatment of cancer | License | Non-exclusive | Lead Molecule | Yes | SEC Redacted | Cancer | Broad Focus Cancer | Monoclonals | Worldwide | |||||||||||
7 | 12/2014 | Tufts University | Tracon Pharmaceuticals | $0.150 | $7.950 | TRC205 ( humanized anti-endoglin antibody) in cardiac fibrosis | License, Option, Research | Exclusive | Preclinical | SEC Redacted | Cardiovascular | Other Cardiovascular | Monoclonals | Humanized Abs | Worldwide | |||||||||||
8 | 11/2014 | Baylor | Bellicum Pharmaceuticals | $0.025 | $0.300 | Methods for Inducing Selective Apoptosis | License | Exclusive | Discovery | Yes | SEC Redacted | Cancer | Broad Focus Cancer | Cell Therapy - Stem Cells/Factors | Worldwide | |||||||||||
9 | 6/2014 | Dartmouth College | Celyad, Celdara Medical | $0.030 | $1.630 | Anti-B7-H6 Immunotherapies | Development, License | Exclusive | Yes | SEC Full | Cancer | Worldwide | ||||||||||||||
10 | 6/2014 | University of Illinois | Cortex Pharmaceuticals | $0.475 | $2.400 | IP related to use of cannabinoids for sleep related breathing disorders | License | Exclusive | Lead Molecule | Yes | SEC Full | Central Nervous System | Sleep Disorders | Synthetics | Small Molecule | Worldwide | ||||||||||
11 | 3/2014 | University of Miami | Heat Biologics | $0.015 | $0.020 | Recombinant gp120 protein vaccination for protection from SIV/HIV | Development, License | Exclusive | Preclinical | Yes | SEC Redacted | Infectious-Viral | Human Immunodeficiency Virus/HIV, Other Infectious-Viral | Vaccines | Worldwide | |||||||||||
12 | 11/2013 | Memorial Sloan Kettering | Juno Therapeutics | $6.900 | $150.000 | JCAR015 (CD19 CAR-T) for immunotherapy of solid tumors & CRO services | Equity, License, Research, Services | Exclusive | Phase I | Yes | SEC Redacted | Cancer | Cell Therapy - Stem Cells/Factors | Worldwide | ||||||||||||
13 | 10/2013 | Ohio State University, Nationwide Childrens Hospital | AveXis | $0.100 | $0.230 | AVXS-101 (human SMN gene) for spinal muscular atrophy (SMA) Type 1 | Equity, License, Research | Exclusive | Preclinical | SEC Redacted | Other/Miscellaneous | Genetic Disorders | Oligonucleotides | Gene Therapy | Worldwide | |||||||||||
14 | 5/2013 | Stanford | Fate Therapeutics | $0.040 | Wnt proteins for stem cell modulation | Equity, License | Exclusive | Discovery | Yes | SEC Redacted | Hematologic, Transplantation | Broad Focus Hematologic, Broad Focus Transplantation | Cell Therapy - Stem Cells/Factors | Worldwide | ||||||||||||
15 | 3/2013 | University of Colorado | Syndax Pharmaceuticals | $0.200 | license and option for novel therapeutics | Development, License, Option | Exclusive | Phase I | Yes | SEC Redacted | Worldwide | |||||||||||||||
16 | 1/2013 | Yale | Bind Therapeutics | $0.025 | Targeted and high density drug-loaded polymeric materials for treatment of cancer | License | Exclusive | Discovery | Yes | SEC Redacted | Cancer | Broad Focus Cancer | Synthetics | Small Molecule | Worldwide | |||||||||||
17 | 9/2012 | Baylor Research Institute | Ultragenyx Pharmaceutical | $0.250 | Tripheptanoin (UX007) for long-chain fatty acid oxidation disorders | Development, License, Option | Exclusive | Phase II | Yes | SEC Redacted | Endocrinological & Metabolic | Other Endocrinological & Metabolic | Synthetics | Small Molecule | Worldwide | |||||||||||
18 | 7/2012 | Dartmouth College | ChromaDex | $0.085 | $0.090 | IP covering pharmaceutical use of nicotinamide riboside | Development, License | Exclusive | Yes | FOIA | Other/Miscellaneous | Nutritionals/Vitamins | Natural Product | Worldwide | ||||||||||||
19 | 6/2012 | Scripps Research Institute | Cempra | $0.585 | $1.690 | Solithromycin macrolides for antibiotic resistance ex-ASEAN | License | Exclusive | Lead Molecule | Yes | SEC Redacted | Infectious-Bacterial | Broad Focus Infectious-Bacterial | Synthetics | Combinatorial | Africa, Asia, Europe, Middle East, NAFTA, South America | All African Countries, All European Countries, All Middle East Countries, All NAFTA Countries, All South American Countries, Australia, China, India, Japan, New Zealand, Other Asian | |||||||||
20 | 5/2012 | Mass General Hospital | ProQR Therapeutics | $0.010 | $0.010 | novel therapeutics for treatment of cystic fibrosis | Development, License | Exclusive | Preclinical | Yes | SEC Redacted | Respiratory | Cystic Fibrosis | Worldwide | ||||||||||||
21 | 4/2012 | University of California, UC San Francisco | PhotoMedex | $0.030 | $0.030 | treatment of psoriasis and other inflammatory skin disease | Development, License | Exclusive | Yes | SEC Full | Dermatologic | Other Dermatologic, Psoriasis | Worldwide | |||||||||||||
22 | 3/2012 | Yale | Medistem | $0.045 | $1.150 | Endometrial derived stem cells to treat diabetes | Development, License | Exclusive | Preclinical | Yes | SEC Full | Endocrinological & Metabolic | Diabetes | Cell Therapy - Stem Cells/Factors | Worldwide | |||||||||||
23 | 1/2012 | NIH | KineMed | $0.290 | $18.040 | 5a peptide for cardio vascular diseases | License | Exclusive | Preclinical | Yes | SEC Full | Cardiovascular | Angina, Atherosclerosis/Coronary Artery Disease, Congestive Heart Failure, Myocardial Infarction, Other Cardiovascular, Peripheral Arterial Disease | Peptides | Worldwide | |||||||||||
24 | 12/2011 | Texas A&M | Oragenics | $0.005 | $0.710 | Site directed mutagenesis of Mutacin 1140 | Development, License | Exclusive | Preclinical | Yes | SEC Full | Peptides | Worldwide | |||||||||||||
25 | 8/2011 | NIH | uniQure | $0.155 | $0.160 | AAV5 based therapeutics for brain and liver diseases | Development, License | Exclusive | Preclinical | Yes | SEC Redacted | Other/Miscellaneous | Oligonucleotides | Gene Therapy | Worldwide | |||||||||||
26 | 8/2011 | Stanford | ImmuMetrix | $0.040 | $0.040 | non-invasive diagnosis of graft rejection in organ transplant | Equity, License, Research | Exclusive | Diagnostic, Device | Yes | SEC Redacted | Transplantation | Organ/Tissue Transplants | Diagnostics | Worldwide | |||||||||||
27 | 7/2011 | University of Michigan | Heat Biologics | $0.060 | $0.810 | blander cancer cell lines | Development, License | Exclusive | Preclinical | Yes | SEC Full | Cancer | Bladder | Worldwide | ||||||||||||
28 | 4/2011 | University of California, UC San Diego, Dana-Farber | Adamis Pharmaceuticals | $0.060 | $1.920 | telomerase reverse transcription antigen for immunization in cancer | Development, License | Exclusive | Phase I | Yes | SEC Full | Cancer | Broad Focus Cancer | Vaccines | NAFTA | US | ||||||||||
29 | 4/2011 | University of Cincinnati | ARCA Biopharma | $0.030 | $0.030 | Patents covering genetic polymorphisms of adrenergic cardiac receptors for companion diagnostic | License | Diagnostic | Yes | SEC Redacted | Cardiovascular | Congestive Heart Failure | Diagnostics | Worldwide | ||||||||||||
30 | 4/2011 | Yissum Research Development | Immune Pharmaceuticals | $0.030 | $15.480 | Antibody nanoparticle conjugates for the targeted delivery_x000D_ of active agents conjugated to antibodie | Development, License, Research | Exclusive | Preclinical | Yes | SEC Full | Drug Delivery, Monoclonals | Human Abs | Worldwide | ||||||||||||
31 | 3/2011 | Cornell University | Strongbridge Biopharma | $0.439 | $3.010 | Commensal bacteria as signal mediators | Development, License | Exclusive | Preclinical | Yes | SEC Full | Worldwide | ||||||||||||||
32 | 3/2011 | New York University | Regulus Therapeutics | $0.025 | novel therapeutics for microRNA 33, metabolic disorders, and atherosclerosis | License | Exclusive | Yes | SEC Redacted | Cardiovascular, Endocrinological & Metabolic | Atherosclerosis/Coronary Artery Disease | Worldwide | ||||||||||||||
33 | 2/2011 | University of Miami | Heat Biologics | $0.010 | $0.010 | Vaccine for treatment of nonsmall cell lung cancer | License | Exclusive | Yes | SEC Redacted | Cancer | Lung | Vaccines | Worldwide | ||||||||||||
34 | 2/2011 | University of Michigan | Medgenics | $0.075 | $3.230 | gene therapy products | License | Exclusive | Preclinical | Yes | SEC Full | Oligonucleotides | Gene Therapy | Worldwide | ||||||||||||
35 | 12/2010 | Weizmann Institute | Prolor Biotech | $0.025 | $0.030 | Long·acting Cytokine pharmaceuticals | Development, License | Exclusive | Yes | FOIA | Worldwide | |||||||||||||||
36 | 10/2010 | San Raffaele Telethon Institute For Gene Therapy | GlaxoSmithKline | $14.000 | Ex vivo gene therapy for adenosine deaminase severe combined immunodeficiency syndrome | Development, License, Option | Exclusive | Phase I | Press Release | Other/Miscellaneous | Genetic Disorders | Oligonucleotides | Gene Therapy | |||||||||||||
37 | 10/2010 | St. Louis University | Ultragenyx Pharmaceutical | $0.010 | $0.110 | Enzyme replacement therapy program to treat mucopolysaccharidosis type 7 | License | Exclusive | Preclinical | Yes | SEC Redacted | Endocrinological & Metabolic | Lysosomal Storage Disorders | Worldwide | ||||||||||||
38 | 8/2010 | Salk Institute | Acceleron | $0.350 | $3.000 | Activin (ACTRII soluble receptors) to treat muscle wasting | License, Research | Exclusive | Lead Molecule | Yes | SEC Full | Endocrinological & Metabolic | Other Endocrinological & Metabolic | Recombinant DNA | Worldwide | |||||||||||
39 | 6/2010 | Baylor | Bellicum Pharmaceuticals | $0.030 | $0.030 | Methods f generating immune response by_x000D_ inducing CD40 and pattern recognition receptors | Development, License | Exclusive | Preclinical | Yes | SEC Redacted | Autoimmune/Inflammatory | Broad Focus Autoimmune/Inflammatory | Diagnostics, Peptides | Worldwide | |||||||||||
40 | 6/2010 | Scripps Research Institute | Poniard Pharmaceuticals, Allozyne | $0.070 | $2.000 | Click chemistry for bioconjugation | Equity, License | Exclusive | Discovery | Yes | SEC Redacted | Unlimited | Synthetics | Combinatorial | Worldwide | |||||||||||
41 | 4/2010 | Dartmouth College | Celyad, Celdara Medical | $0.020 | $1.520 | Chimeric NKG2D receptor-based T cell therapies | License | Exclusive | Preclinical | Yes | SEC Full | Cancer | Worldwide | |||||||||||||
42 | 1/2010 | Scripps Research Institute | Sorrento Therapeutics | $0.010 | $1.760 | antibodies and vaccines for infectious disease | Development, Equity, License | Exclusive | Discovery | Yes | FOIA | Infectious-Bacterial | Monoclonals, Vaccines | Humanized Abs | ||||||||||||
43 | 11/2009 | City of Hope | Juno Therapeutics, Zeta Acquisition | $0.025 | CAR constructs for genetically engineered white blood cells | License | Exclusive | Lead Molecule | Yes | SEC Redacted | Unlimited | Cell Therapy - Stem Cells/Factors | Worldwide | |||||||||||||
44 | 10/2009 | Dana-Farber | Transgenomic | $0.220 | $0.390 | Methods of mutation detection | Development, License | Non-exclusive | Diagnostic | Yes | SEC Full | Diagnostics | DNA Probes | Worldwide | ||||||||||||
45 | 10/2009 | Xoma | Kaketsuken | $8.000 | $8.200 | XOMA020 antibody phage display library | License | Semi-exclusive | Discovery | Yes | FOIA | Unlimited | Monoclonals | Worldwide | ||||||||||||
46 | 6/2009 | Mayo Foundation, Mayo Clinic | Exact Sciences | $0.080 | $1.330 | Non-invasive DNA screening diagnostic tests for colorectal cancer | Development, License | Exclusive | Diagnostic | Yes | SEC Redacted | Cancer | Colorectal | Diagnostics | Worldwide | |||||||||||
47 | 5/2009 | University of Minnesota | Celladon | $0.240 | $0.240 | Small molecule compounds that modulate SERCA activity for cardio diseases | License | Exclusive | Lead Molecule | Yes | SEC Redacted | Cardiovascular | Broad Focus Cardiovascular | Screening | Worldwide | |||||||||||
48 | 4/2009 | Bristol-Myers Squibb, University of Massachusetts, Medarex, MassBiologics | Merck | $60.000 | $225.000 | CDA-1 and CDB-1 mAb combination for Clostridium difficile infection | Development, License | Exclusive | Phase II | Press Release | Infectious-Bacterial | Other Infectious-Bacterial | Monoclonals | Human Abs | Worldwide | |||||||||||
49 | 4/2009 | NIH | MRI Interventions | $0.038 | $0.190 | Devices and systems for MRI-guided medical procedures | Development, License | Non-exclusive | Yes | SEC Redacted | Device, Diagnostics | Asia, Europe, Middle East, NAFTA | All European Countries, Australia, Canada, China, Israel, Japan, US | |||||||||||||
50 | 3/2009 | Indiana University | Cellular Dynamics International | $0.100 | $4.100 | Myocardial grafts | Development, License | Exclusive | Preclinical | Yes | FOIA | Cardiovascular | Myocardial Infarction | Cell Therapy - Stem Cells/Factors | Worldwide | |||||||||||
51 | 2/2009 | Johns Hopkins | Bind Therapeutics | $0.030 | $1.000 | Nanoparticles targeting PSMA for prostate cancer treatment | License | Exclusive | Lead Molecule | Yes | SEC Redacted | Cancer | Prostate | Synthetics | Small Molecule | Worldwide | ||||||||||
52 | 12/2008 | Ottawa Hospital Research Institute | Fate Therapeutics, Verio Therapeutics | $0.060 | Wnt7a and analogs for treatment of muscle degeneration | Equity, License | Exclusive | Lead Molecule | Yes | SEC Redacted | Endocrinological & Metabolic, Hematologic, Other/Miscellaneous | Broad Focus Hematologic, Genetic Disorders, Lysosomal Storage Disorders | Cell Therapy - Stem Cells/Factors | Worldwide | ||||||||||||
53 | 12/2008 | University of Tennessee Research Foundation | ProThera Biologics, Elan | $0.080 | $0.080 | Novel therapeutics for treatment and prophylaxis of Amyloidosis | License | Exclusive | Yes | SEC Full | Other/Miscellaneous | Worldwide | ||||||||||||||
54 | 11/2008 | University of Western Australia | Sarepta Therapeutics | $0.038 | $0.110 | Treatment of Duchenne MD using exon skipping oligonucleotide technology | Assignment, License | Exclusive | Lead Molecule | Yes | SEC Full | Other/Miscellaneous | Genetic Disorders | Oligonucleotides | ||||||||||||
55 | 7/2008 | St. Jude Children's Research Hospital | uniQure, Amsterdam Molecular Therapeutics | $0.010 | $0.010 | gene therapy for Hemophilia B | Development, License | Exclusive | Yes | SEC Redacted | Hematologic | Hemophilia | Oligonucleotides | Gene Therapy | Worldwide | |||||||||||
56 | 7/2008 | UC San Diego | Synthetic Biologics, Epitope | $0.137 | $11.490 | Novel immunotherapies for treatment of Rheumatoid Arthritis | License | Exclusive | Preclinical | Yes | SEC Full | Autoimmune/Inflammatory | Rheumatoid Arthritis | Peptides, Vaccines | Worldwide | |||||||||||
57 | 7/2008 | University of Miami | Heat Biologics | $0.150 | $0.400 | ImPACT technology as cancer vaccine | Equity, License | Exclusive | Lead Molecule | Yes | SEC Redacted | Cancer | Broad Focus Cancer | Cell Therapy - Stem Cells/Factors, Transgenics | Worldwide | |||||||||||
58 | 6/2008 | Johns Hopkins | MRI Interventions | $0.075 | $0.080 | Catheter-based MRI probes | License | Exclusive | Device | Yes | SEC Redacted | Device | Worldwide | |||||||||||||
59 | 6/2008 | Mayo Foundation | Nile Therapeutics | $0.285 | $49.790 | Natriuretic polypeptides | Development, Equity, License | Exclusive | Phase I | Yes | FOIA | Cardiovascular, Renal | Peptides | Worldwide | ||||||||||||
60 | 5/2008 | Johns Hopkins, Duke University | Duska Therapeutics | $0.680 | $2.330 | Reactive Oxygen Generating enzyme and inhibitor with Nitric Oxide Bioactivity | Development, Equity, License | Exclusive | Lead Molecule | Yes | FOIA | Worldwide | ||||||||||||||
61 | 5/2008 | Virginia Commonwealth University | Oxygen Biotherapeutics | $0.070 | $1.550 | Gas based wound and tissue therapeutics | Development, Equity, License | Exclusive | Preclinical | Yes | SEC Full | Dermatologic | Wound Healing | Worldwide | ||||||||||||
62 | 5/2008 | Yale | Kolltan Pharmaceuticals | $0.050 | $0.350 | monoclonal antibodies targeting receptor tyrosine kinases for therapeutics | License, Research | Exclusive | Yes | SEC Redacted | Monoclonals | Humanized Abs | Worldwide | |||||||||||||
63 | 2/2008 | Buck Institute | Neurobiological Technologies | $0.175 | $1.380 | Netrin-1 protein | Development, License, Research | Exclusive | Preclinical | Yes | FOIA | Worldwide | ||||||||||||||
64 | 2/2008 | Salk Institute | uniQure | $0.065 | $0.070 | DNA promoter to enhance gene therapy for lipoprotein lipase deficiency | License | Non-exclusive | Discovery | Yes | SEC Redacted | Other/Miscellaneous | Genetic Disorders | Oligonucleotides | Gene Therapy | Worldwide | ||||||||||
65 | 1/2008 | Rockefeller University | Rosetta Genomics | $0.040 | $0.040 | microRNAs for research purposes | License | Non-exclusive | Reagent | Yes | SEC Redacted | Oligonucleotides | RNAi | Worldwide | ||||||||||||
66 | 1/2008 | Wisconsin Alumni Research Foundation | Biotime | $0.250 | $0.250 | human embryonic stem cells | License, Option | Exclusive | Yes | SEC Full | Cell Therapy - Stem Cells/Factors | Worldwide | ||||||||||||||
67 | 1/2008 | Yeda | Histogenics, ProChon | $0.002 | $0.020 | Expression of heterologous proteins | Development, License | Exclusive | Discovery | Yes | SEC Redacted | Unlimited | Recombinant DNA | Worldwide | ||||||||||||
68 | 12/2007 | MIT, Versitech | Arch Therapeutics | $0.095 | $1.000 | Novel peptides to control surgical adhesions | License | Exclusive | Lead Molecule | Yes | SEC Full | Dermatologic | Wound Healing | Peptides | Worldwide | |||||||||||
69 | 11/2007 | Buck Institute | Neurobiological Technologies | $0.175 | $34.810 | Fibroblast growth factor-2 for treatment of ischemia and Huntington's Disease | Development, License, Research | Exclusive | Preclinical | Yes | FOIA | Cardiovascular, Central Nervous System | Other Cardiovascular, Other Central Nervous System | Worldwide | ||||||||||||
70 | 11/2007 | Burnham Institute | Biotime | $0.040 | $0.040 | Novel homing peptides for cell coatings capable of directing cells to specific organs | License | Exclusive | Yes | SEC Full | Cancer, Dermatologic | Solid Tumors, Wound Healing | Peptides | Worldwide | ||||||||||||
71 | 11/2007 | University College London | Fortress Biotech, Coronado Biosciences | $0.100 | $22.080 | Tumor restricted natural killer cells for therapeutic use | Development, License | Exclusive | Preclinical | Yes | FOIA | Cancer | Solid Tumors | Worldwide | ||||||||||||
72 | 10/2007 | University of California, UC San Diego | Raptor Pharmaceuticals, Encode Pharmaceuticals | $0.070 | $6.350 | enterically coated cysteamine for cystinosis, Huntington's, Batten's, schizophrenia | Development, License | Exclusive | Phase II | Yes | FOIA | Central Nervous System, Endocrinological & Metabolic, Psychiatric | Lysosomal Storage Disorders, Other Central Nervous System, Schizophrenia | Drug Delivery | Controlled Release, Oral | Worldwide | ||||||||||
73 | 9/2007 | University of Georgia | Bristol-Myers Squibb, Inhibitex | $0.750 | $32.550 | HIV integrase & HCV polymerase Inhibitors | Equity, License, Research | Exclusive | Preclinical | Yes | FOIA | Infectious-Viral | Broad Focus Infectious-Viral, Hepatitis C, Human Immunodeficiency Virus/HIV | Synthetics | Small Molecule | Worldwide | ||||||||||
74 | 6/2007 | Mayo Foundation | Celyad | $12.769 | $17.140 | Stem cell based therapy for non-ischemic cardiomyopathic heart failure | Equity, License, Research | Exclusive | Yes | SEC Full | Cardiovascular | Other Cardiovascular | Cell Therapy - Stem Cells/Factors | Worldwide | ||||||||||||
75 | 5/2007 | Baylor | Inovio Pharmaceuticals, VGX Animal Health | $0.025 | $0.950 | novel therapeutics | Development, License | Exclusive | Preclinical | Yes | SEC Redacted | Worldwide | ||||||||||||||
76 | 5/2007 | NIH | uniQure | $0.027 | $0.030 | AMT-010 for Lipoprotein Lipase Deficiency Type I and V deficiency | Development, License, Research | Non-exclusive | Preclinical | Yes | SEC Redacted | Endocrinological & Metabolic | Other Endocrinological & Metabolic | Oligonucleotides | Gene Therapy | Asia, Europe, NAFTA | All European Countries, Australia, Canada, US | |||||||||
77 | 5/2007 | University of Alberta | Cortex Pharmaceuticals | $0.035 | $0.310 | Method of inhibiting respiratory depression using AMPAKINEs | Development, License | Exclusive | Phase I | Yes | FOIA | Respiratory | Other Respiratory | Worldwide | ||||||||||||
78 | 4/2007 | Scripps Research Institute | Repligen | $0.325 | $4.880 | novel therapeutics for Friedreich's ataxia | Development, Equity, License | Exclusive | Phase II | Yes | FOIA | Central Nervous System | Other Central Nervous System | Worldwide | ||||||||||||
79 | 4/2007 | University of Pennsylvania | Inovio Pharmaceuticals, VGX Animal Health | $1.300 | $3.800 | HIV, HPV, HCV vaccines | Development, License | Exclusive | Phase I | Yes | SEC Redacted | Infectious-Viral | Hepatitis C, Human Immunodeficiency Virus/HIV, Influenza, Other Infectious-Viral | Vaccines | Worldwide | |||||||||||
80 | 2/2007 | University of Washington | GenMark Diagnostics | $0.060 | $0.060 | Methods and compositions for predicting drug responses | License | Non-exclusive | Yes | FOIA | Worldwide | |||||||||||||||
81 | 2/2007 | Washington University | Prolor Biotech | $0.115 | $0.200 | Carboxy terminal peptide-extended proteins and N-terminal CTP extended pharmaceutical peptides | Development, Equity, License | Exclusive | Phase I | Yes | SEC Full | Peptides | Worldwide | |||||||||||||
82 | 1/2007 | Baylor | Medgenics | $0.045 | $0.150 | Helper-Dependent Adenoviral Vectors for gene therapy | Development, License | Non-exclusive | Discovery | Yes | SEC Full | Oligonucleotides | Gene Therapy | Worldwide | ||||||||||||
83 | 1/2007 | University of Massachusetts | RXi Pharmaceuticals | $0.083 | $3.820 | RNA Interference Agents for Therapeutic Use | Development, Equity, License | Exclusive | Phase I | Yes | FOIA | Central Nervous System, Endocrinological & Metabolic | Amyotrophic Lateral Sclerosis, Diabetes, Obesity | Oligonucleotides | RNAi | Worldwide | ||||||||||
84 | 1/2007 | University of Massachusetts | RXi Pharmaceuticals | $0.035 | $3.700 | Gene silencing with siRNA containing mismatches to targets | Development, License | Exclusive | Phase I | Yes | FOIA | Central Nervous System | Amyotrophic Lateral Sclerosis | Oligonucleotides | RNAi | Worldwide | ||||||||||
85 | 1/2007 | University of Massachusetts | RXi Pharmaceuticals | $0.030 | $0.340 | Microwave assisted method of synthesis of new cationic reagents for efficient drug delivery | Development, Equity, License | Non-exclusive | Yes | FOIA | Drug Delivery | Worldwide | ||||||||||||||
86 | 1/2007 | University of Massachusetts | RXi Pharmaceuticals | $0.145 | $4.470 | Therapeutic silencing of genes involved in cholesterol biosynthesis by chemically modified siRNA | Development, Equity, License | Exclusive | Phase I | Yes | FOIA | Endocrinological & Metabolic | Broad Focus Endocrinological & Metabolic | Oligonucleotides | RNAi | Worldwide | ||||||||||
87 | 1/2007 | University of South Florida | MIMEDX | $0.225 | $0.430 | novel therapeutics in the field of polymerized collagen fibers for ligament repair | Development, Equity, License | Exclusive | Yes | SEC Full | Other/Miscellaneous | Collagen matrix | Worldwide | |||||||||||||
88 | 1/2007 | Wisconsin Alumni Research Foundation | Adamis Pharmaceuticals, Colby Pharmaceuticals | $0.025 | $0.650 | Chroman-derived anti-androgens for treatment of androgen mediated disorders | Development, Equity, License | Exclusive | Phase I | Yes | SEC Full | Cancer | Prostate | Worldwide | ||||||||||||
89 | 12/2006 | Johns Hopkins | MRI Interventions | $0.035 | $0.040 | MRI safety technologies | License, Sublicense | Exclusive | Device | Yes | SEC Redacted | Device | Worldwide | |||||||||||||
90 | 12/2006 | MIT | Cerulean | $0.040 | Nanoparticles containing selected polymers | Equity, License | Exclusive | Lead Molecule | Yes | SEC Redacted | Synthetics | Polymers | Worldwide | |||||||||||||
91 | 12/2006 | University of Washington | Achaogen | $0.100 | $3.350 | ACHN-975 ( LpxC inhibitor) antibacterial compounds | Equity, License | Exclusive | Lead Molecule | Yes | SEC Redacted | Infectious-Bacterial | Broad Focus Infectious-Bacterial | Worldwide | ||||||||||||
92 | 9/2006 | Duke University | Celldex | $0.675 | $2.790 | vaccines and antibodies for glioblastoma multiforme and brain cancers | Equity, License, Research | Exclusive | Yes | FOIA | Cancer | Brain | Monoclonals, Vaccines | Humanized Abs | Worldwide | |||||||||||
93 | 9/2006 | Johns Hopkins | Rosetta Genomics | $0.125 | $0.400 | Novel miRNAs | Development, License | Exclusive | Lead Molecule | Yes | FOIA | Oligonucleotides | RNAi | Worldwide | ||||||||||||
94 | 8/2006 | Johns Hopkins | Rosetta Genomics | $0.125 | $0.130 | Human miRNAs and Their Evaluation with a Dicer KO | License | Non-exclusive | Yes | SEC Redacted | Worldwide | |||||||||||||||
95 | 8/2006 | University of Illinois | Opko Health | $0.250 | $2.250 | Novel therapuetics for treatment of ophthalmic diseases | Development, License | Exclusive | Preclinical | Yes | SEC Full | Ophthalmic | Broad Focus Ophthalmic | Worldwide | ||||||||||||
96 | 6/2006 | Max Planck Institute | Rosetta Genomics | $0.302 | $0.300 | Small expressed RNA molecules | License | Semi-exclusive | Yes | FOIA | Oligonucleotides | Worldwide | ||||||||||||||
97 | 6/2006 | University of Pennsylvania | NuPathe | $0.170 | $2.820 | LAD(TM) long acting delivery technology for neurologic and psychiatric disorders | License | Exclusive | Phase I | Yes | FOIA | Central Nervous System, Psychiatric | Broad Focus Central Nervous System, Broad Focus Psychiatric, Parkinson's Disease, Schizophrenia | Drug Delivery | Sustained Release | Worldwide | ||||||||||
98 | 5/2006 | Children's Hospital Boston | Alseres Pharmaceuticals | $0.010 | $0.790 | Use of inosine and other molecules for treatment of Central and Peripheral Nervous System diseases | Development, License, Option, Research | Exclusive | Preclinical | Yes | FOIA | Central Nervous System | Broad Focus Central Nervous System, Other Central Nervous System, Spinal Cord Injury, Stroke | Worldwide | ||||||||||||
99 | 5/2006 | Rockefeller University | Rosetta Genomics | $0.100 | $0.100 | Micro RNA sequences for analyte specific reagents | License | Semi-exclusive | Diagnostic, Reagent | Yes | FOIA | Diagnostics, Oligonucleotides | DNA Probes, RNAi | Worldwide | ||||||||||||
100 | 5/2006 | University of Massachusetts | RXi Pharmaceuticals, CytRx | $0.100 | $2.250 | siRNA for treatment of diabetes, obesity, ALS, and human cytomegalovirus (HCMV) | Development, Equity, License | Semi-exclusive | Preclinical | Yes | FOIA | Central Nervous System, Endocrinological & Metabolic, Infectious-Viral | Amyotrophic Lateral Sclerosis, Cytomegalovirus/CMV, Diabetes | Oligonucleotides | RNAi | Worldwide |