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Patient (Demand)Treatment
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ConditionsDiseasesIncidence RateUndiagnosed PopulationPatient Demo (skews young, ethnicity, etc.)Current Spend Levels
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CardiovascularHypertension116 million US adults.About 11 million adultsThe percentage of hypertension is greater in men (50%) and non-Hispanic black adults (56%).High; Between $131 and $198 billion annually.
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Coronary Heart DiseaseAbout 18.2 million Americans aged 20 and above have Coronary Heart Disease. High Undiagnosed Population; The disease is usually not diagnosed until after a heart attack or cardiac arrest. CAD is most common in older adults and Hispanic Americans. High; $80 billion annually
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Heart Failure6.2 milllion American adults have Heart Failure.N/AHeart Failure is prevalent among females, older adults, and Black Americans.High; Heart Failure costs the US $30.7 billion in 2012. The average annual cost of medical care per patient is $24,383.
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HyperlipidemiaAbout 94 million Americans aged 20 or older and 7% of children and adolescents.High Undiagnosed Population; Many Americans are unaware of their high cholesterol levels. Hyperlipidemia is most prevalent among Non-Hispanic White Females (14.8%) and Hispanic Males (13.1%).N/A
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Atrial FibrillationAn estimated 2.7 million to 6.1 million Americans have Atrial Fibrillation.Low Undiagnosed Population; 698,900 Americans.Prevalence is higher among older male adults as the possibility of occurence increases with age. About 70% of people diagnosed with the condition are between ages 65 and 85.N/A
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StrokeAnnually, more than 795,000 Americans have a stroke..N/AStrokes are more common among blacks than whites. The possibility of occurence also increases with age. High; $45.5 billion annually, including direct and indirect costs.
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Ischemic Heart Disease It is also referred to as Coronary Heart Disease or Coronary Artery Disease (CAD). About 18.2 million Americans aged 20 and above have Coronary Heart Disease. High Undiagnosed Population; The disease is usually not diagnosed until after a heart attack or cardiac arrest. It is most common in older adults and Hispanic Americans. High; $80 billion annually
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High CholesterolIt is also known as Hyperlipidemia. It affects about 94 million Americans aged 20 or older and 7% of children and adolescents.High Undiagnosed Population; Many Americans are unaware of their high cholesterol levels. Hyperlipidemia is most prevalent among Non-Hispanic White Females (14.8%) and Hispanic Males (13.1%).N/A
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High blood pressureAlso known as hypertension, it affects 116 million US adults.About 11 million adultsThe percentage of hypertension is greater in men (50%) and non-Hispanic black adults (56%).High; Between $131 and $198 billion annually.
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ChronicCHFAlmost 5 million Americans are living with CHF.N/AIt is most common among older adults with its probability of occurence increasing with age.N/A
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Obesity42% of the population is considered obeseLow undiagnosed population; Physically visibleSlight Skew; Non-Hispanic Black adults (49.6%) had the highest age-adjusted prevalence of obesity, followed by Hispanic adultsHigh; $173B annually (due to complications, etc.); Est ~1.9K incremental pp
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Chronic Liver Disease1.8% (4.5 million) of people in the US live with Chronic Liver Diasease.High Undiagnosed Population; Patients are often unaware of their status as symptoms do not manifest until after many years. Prevelent among adults aged 45 to 54.N/A
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Chronic Kidney DiseaseAn estimated 15% (37 million) of US adults have Chronic Kidney Disease. High Undiagnosed Population; 9 in 10 patients remain undiagnosed and are ignorant of their condition.It is prevalent in adults aged 65 and above. Medicare costs for patients with CKD in 2018 was $81.8 billion.
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Dental / OralGingivitisAlthougjh its prevalence is difficult to determine, it is believed that 50% of American adults have had Gingivitis on 3-4 teeth and that 9-17% of children within ages 3-14 have Gingivitis. N/AGingivitis is common among males, people who smoke, and people who live in poverty.N/A
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ThrushN/A. There is no national surveillance for this infection in the US. N/AThe risk of Thrush, also known as oral candidiasis, is higher among babies and people with underlying conditions such as diabetes, cancer, and HIV/AIDS.N/A
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DevelopmentalCerebral palsyCerebral Palsy affects 764,000 adults and children in the US. N/ABlack male children are more likely than others to have cerebral palsy.The US spends $10.2 billion annually in providing relief, care, and support to patients.
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Hearing loss13% (30 million) of Americans aged 12 years or older have hearing loss in both ears.N/ANon-Hispanic white males are more likely to experience hearing loss. Among adults, people aged 60-69 have an increased chance of hearing loss. N/A
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Digestive & GastrointestinalReflux / GERD20% of the US populationN/AIts prevalence is not dependent on age or ethnicity. N/A
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Celiac DiseaseAn estimated 2 million Americans have celiac disease. High Undiagnosed Population; many victims of the disease are yet to be diagnosed.The risk of celiac disease is greater among White Americans, females, and people with chromosomal disorders.N/A
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IBS / IBD1.3% of US adults (3 million)High Undiagnosed Population; a large number of cases remain undiagnosed and untreated.Prevalence is high among White Americans. Approximately $14 billion.
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Ulcerative Colitis1 million people in the US.N/AThe disease affects people of all ages. However, people within ages 15-30 and 50-70 are more likely to be affected.N/A
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Lactose Intolerance30 million American adults aged 20 and above.N/ALactose intolerance is most common among Africans, Asians, Hispanics, and American Indians.N/A
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Ear, Nose and ThroatEar Infection5 out of 6 children in the US experience ear infection by the time they turn 3 years old.It is unclear how many undiagnosed cases of ear infectios exist in the US. However, research has shown that ear infections are misdiagnosed up to 50% of the time using the otoscope.White children are more likely to have frequent ear infections than cjhildren from other races. N/A
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Hearing loss13% (30 million) of Americans aged 12 years or older have hearing loss in both ears.N/ANon-Hispanic white males are more likely to experience hearing loss. Among adults, people aged 60-69 have an increased chance of hearing loss. N/A
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Sinusitis1 in 7 adults in the US and over 30 (11.6% of the population) million individuals diagnosed annually.N/AN/AN/A
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Sleep Apnea22 million Americans experience Sleep Apnea.High Undiagnosed Population; 80% of the cases of moderate and severe obstructive sleep apnea are undiagnosed.The condition is more "prevalent in men than in women and increases with age and obesity."N/A
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EndocrineHypothyroidism
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Hyperthyroidism
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Low Testosterone
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Osteoporosis
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Polycystic Ovary Syndrome (PCOS)
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EyeCataracts
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Macular degeneration
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Glaucoma
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NeurologicalMigraines
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Multiple Sclerosis
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Quadriplegia
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Spina Bifida
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Transient Ischemic Attack (TIA)
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OncologyBreast Cancer
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Lung Cancer
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Bronchus Cancer
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Lymphoma
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Sarcomas
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RheumatologyOsteoarthritis
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Fibromyalgia
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Lupus
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Urinary Tract and RenalOveractive Bladder
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