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Variable NameRelevant ValuesTypeShort Description
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record_idNumericPatient's ID number.
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redcap_repeat_instrumentStringVariable indicating whether the row refers to the patient's general information or a specific biopsy fragment (each patient will have a general row plus one row for each biopsy fragment).
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redcap_repeat_instanceNumericVariable linked to the previous one: indicates the biopsy fragments with a progressive number based on their insertion order.
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comune_residenzaStringMunicipality of residence at the time of diagnosis.
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eta_diagnosiNumericAge at the time of diagnosis.
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SDI_cat_regPossible values: 1, 2, 3, 4, 5.CategoricalSocial Deprivation Index (categorical) updated with 2011 ISTAT Date (https://www.istat.it/it/archivio/104317) at the regional level.
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SDI_cont_regNumericSocial Deprivation Index (continuous) updated with 2011 ISTAT Date (https://www.istat.it/it/archivio/104317) at the regional level.
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SDI_cat_ITPossible values: 1, 2, 3, 4, 5.CategoricalSocial Deprivation Index (categorical) updated with 2011 ISTAT Date (https://www.istat.it/it/archivio/104317) at national level.
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SDI_cont_ITNumericSocial Deprivation Index (continuous) updated with 2011 ISTAT Date (https://www.istat.it/it/archivio/104317) at national level.
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SDI_cat_reg_3Possible values: 1, 2, 3.CategoricalSocial Deprivation Index (categorical) updated with 2011 ISTAT Date (https://www.istat.it/it/archivio/104317).
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hospital_distanceNumericDistance from Study Hospital (in meters).
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im_prPossible values: NaN, 0, 1.NumericMyocardial infacrtion.
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chf_prPossible values: NaN, 0, 1.NumericCongestive heart failure.
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pvd_praPossible values: NaN, 0, 1.NumericPeripheral vascular disease.
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cvd_prPossible values: NaN, 0, 1.NumericCerebrovascular disease.
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dems_prPossible values: NaN, 0, 1.NumericDementia.
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cpd_prPossible values: NaN, 0, 1.NumericChronic pulmonary disease.
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reum_prPossible values: NaN, 0, 1.NumericRheumatologic disease.
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ulcer_prPossible values: NaN, 0, 1.NumericPeptic ulcer disease.
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mliver_prPossible values: NaN, 0, 1.NumericLiver disease (mild).
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diab_prPossible values: NaN, 0, 1.NumericDiabetes (mild to moderate).
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diabcc_prPossible values: NaN, 0, 2.NumericDiabetes (with chronic complications).
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emip_prPossible values: NaN, 0, 2.NumericHemiplegia or paraplegia.
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renal_prPossible values: NaN, 0, 2.NumericRenal disease.
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tum_prPossible values: NaN, 0, 2.NumericAny malignancy, (including lymphoma and leukaemia).
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sevliv_prPossible values: NaN, 0, 3.NumericLiver disease (moderate to severe).
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mettum_prPossible values: NaN, 0, 6.NumericMetastatic solid tumour.
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aids_prPossible values: NaN, 0, 6.NumericHIV/AIDS.
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punt_rNumericSum of comorbidities.
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punt_crPossible values: NaN, 0, 1, 2, 3.NumericCharlson-Romano index.
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data_refertoDate format: yyyy-mm-ddDateDate of biopsy report.
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ward_recodedPossible values: 1, 2.CategoricalNumber of the pathology division that evaluated the biopsy fragment.
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extra_prostatica___10 = No,
1 = Yes.
CategoricalExtra-prostatic perineural extension.
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extra_prostatica___20 = No,
1 = Yes.
CategoricalExtra-prostatic periganglionic extension.
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extra_prostatica___30 = No,
1 = Yes.
CategoricalExtra-prostatic extension into adipose tissue.
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extra_prostatica___40 = No,
1 = Yes.
CategoricalExtra-prostatic extension into seminal vesicles.
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extra_prostatica___50 = No,
1 = Yes.
CategoricalExtra-prostatic muscular extension.
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extra_prostatica___60 = No,
1 = Yes.
CategoricalExtra-prostatic vascular extension.
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extra_prostatica___70 = No,
1 = Yes.
CategoricalExtra-prostatic lymphatic extension.
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extra_prostatica___80 = No,
1 = Yes.
CategoricalExtra-prostatic periurethral duct extension.
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metastasi_diagnosi0 = No,
1 = Yes.
CategoricalMetastasis at the time of diagnosis.
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diagnosi_referto_istoStringVariable where the complete diagnosis from the report is recorded.
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lettera_identificativaStringIdentifying letter of the biopsy fragment considered in that row.
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diagnosi___10 = No,
1 = Yes.
CategoricalAdenocarcinoma
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diagnosi___20 = No,
1 = Yes.
CategoricalNegative
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diagnosi___30 = No,
1 = Yes.
CategoricalHigh-grade prostatic intraepithelial neoplasia (HGPIN).
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diagnosi___40 = No,
1 = Yes.
CategoricalAtypical small acinar proliferation (ASAP).
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diagnosi___50 = No,
1 = Yes.
CategoricalInflammation.
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diagnosi___60 = No,
1 = Yes.
CategoricalProstatic intraepithelial neoplasia (PIN).
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diagnosi___70 = No,
1 = Yes.
CategoricalAtrophy.
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diagnosi___80 = No,
1 = Yes.
CategoricalTransitional metaplasia.
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diagnosi___90 = No,
1 = Yes.
CategoricalDiagnosi: metaplasia pavimentosa.
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diagnosi___100 = No,
1 = Yes.
CategoricalSquamous metaplasia
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diagnosi___110 = No,
1 = Yes.
CategoricalBasal cell hyperplasia.
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diagnosi___120 = No,
1 = Yes.
CategoricalNeuroendocrine differentiation.
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diagnosi___130 = No,
1 = Yes.
CategoricalMucinous or muciparous features.
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diagnosi___140 = No,
1 = Yes.
CategoricalNecrosis.
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diagnosi___150 = No,
1 = Yes.
CategoricalAcinar type.
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diagnosi___160 = No,
1 = Yes.
CategoricalFoamy gland variant.
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diagnosi___170 = No,
1 = Yes.
CategoricalOther.
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altro_diagnosiStringFree-text field filled in case diagnosis_17 = 1.
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n_cellule_tumoraliNumericPercentage of tumor cells in the biopsy fragment.
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imputed_coresNumericNumber of cores extracted at biopsy, after the imputation of the missing Date.
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biopsie_neg_precedentiNumericNumber of previous negative biopsies.
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prima_biopsia_negativaDate format: yyyy-mm-ddDateDate of the first previous negative biopsy.
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esplorazione_rettale0 = No,
1 = Yes.
CategoricalDigital rectal examination.
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esito_er0 = No,
1 = Yes.
CategoricalDigital rectal examination outcome.
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ecografia_transrettale0 = No,
1 = Yes.
CategoricalTransrectal ultrasound examination (TRUS).
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esito_ecografia_trus0 = No,
1 = Yes.
CategoricalTransrectal ultrasound examination (TRUS) outcome.
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tc_pet0 = No,
1 = Yes.
CategoricalCT or PET scan examination.
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risonanza_magnetica0 = No,
1 = Yes.
CategoricalMagnetic Resonance Imaging (MRI) examination.
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esito_rm0 = No,
1 = Yes.
CategoricalMRI examination outcome.
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sbot0 = No,
1 = Yes.
CategoricalTotal Body Bone Scan (SOBT) examination.
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ecografia_transperineale0 = No,
1 = Yes.
CategoricalTransperineal ultrasound examination.
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psaNumericPSA level.
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psa_aumentato0 = No,
1 = Yes.
CategoricalPSA increase.
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gleason_primarioNumericPrimary Gleason score.
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gleason_secondarioNumericSecondary Gleason score.
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gleason_totaleStringGleason score.
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ctStringcT value of the cTNM.
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cnStringcN value of the cTNM.
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cmStringcM value of the cTNM.
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cTStringcT value of the cTNM, imputed using the information on PSA and the descriptions available in the pathology reports.
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cT_principalePossible values: 1, 2, 3.CategoricalcT (witout subcategories) value of the cTNM, imputed using the information on PSA and the descriptions available in the pathology reports.
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cT_secondarioPossible values: 1.3, 2, 2.1, 2.2, 2.3, 3.CategoricalcT (with subcategories) value of the cTNM, imputed using the information on PSA and the descriptions available in the pathology reports.
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ISUPInternational Society of Urological Pathology (ISUP) grade group, evaluated using the Gleason score reported in the clinical records.
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ctnmStringComplete cTNM value.
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biopsia0 = No,
1 = Yes.
CategoricalPost-diagnosis biopsies.
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Date_biopsiaDate format: yyyy-mm-ddDateDate of the first post-diagnosis biopsy.
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esito_biopsiaStringBiopsy outcome.
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turp0 = No,
1 = Yes.
CategoricalTransurethral resection of the prostate (TURP) after diagnosis.
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Date_turpDate format: yyyy-mm-ddDateDate of TURP after diagnosis.
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esito_turpStringTURP outcome.
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prostatectomia0 = No,
1 = Yes.
Categoricalprostatectomy.
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Date_prostatectomiaDate format: yyyy-mm-ddDateDate of prostatectomy.
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time_delta_BioProsNumericalTime difference (in days) between biopsy and prostatectomy dates.
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primario_BioPros0 = No,
1 = Yes.
CategoricalIndicates whether prostatectomy treatment occurred within the first six months.
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p_gleason_score_primarioNumericPrimary Gleason score after prostatectomy.
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p_gleason_score_secondarioNumericSecondary Gleason score after prostatectomy.