ABCDEFGHIJKLMNOPQRSTUVWXYZ
1
Cosmetic Products Regulation, Annex II - Prohibited Substances
2
Note: Group entries are split in different rows.
3
4
Substance Identification
5
Substance NameName
Product type, body parts
Maximum Threshold
Restriction(s)
Notes
6
(+/-)-2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propyl-1,1,2,2-Tetrafluoroethylether
(+/-)-2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propyl-1,1,2,2-Tetrafluoroethylether
All cosmetic products
0 %
7
(+/-)-Tetrahydrofurfuryl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate;Quizalofop-p-tefuryl (ISO)
Quizalofop-p-tefuryl (ISO)
All cosmetic products
0 %
8
(+/-)-Tetrahydrofurfuryl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate;Quizalofop-p-tefuryl (ISO)
(+/-)-Tetrahydrofurfuryl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate
All cosmetic products
0 %
9
(1,3,4,5,6,7-Hexahydro-1,3-dioxo-2H-isoindol-2-yl)methyl (1R-trans)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate
(1,3,4,5,6,7-Hexahydro-1,3-dioxo-2H-isoindol-2-yl)methyl (1R-trans)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate
All cosmetic products
0 %
10
(1R,4S,5R,8S)-1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene
(1R,4S,5R,8S)-1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene
All cosmetic products
0 %
11
(1R,4S,5R,8S)-1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8, 8a-octahydro-1,4:5,8-dimethano-naphthalene
(1R,4S,5R,8S)-1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8, 8a-octahydro-1,4:5,8-dimethano-naphthalene
All cosmetic products
0 %
12
(1RS,2SR,5RS)-2-(4-Chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl) cyclopentanol;Ipconazole, (1R,2S,5R)-rel-
Ipconazole, (1R,2S,5R)-rel-(1RS,2SR,5RS)-2-(4-Chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl) cyclopentanol
All cosmetic products
0 %
Applies from 1 March 2022
13
(1RS,2SR,5SR)-2-(4-Chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl) cyclopentanol;Ipconazole, (1R,2S,5S)-rel
(1RS,2SR,5SR)-2-(4-Chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl) cyclopentanolIpconazole, (1R,2S,5S)-rel
All cosmetic products
0 %
Applies from 1 March 2022
14
(2-Acetoxyethyl)trimethylammonium hydroxide(2-Acetoxyethyl)trimethylammonium hydroxide
All cosmetic products
0 %
15
(2-Chloroethyl)(3-hydroxypropyl)ammonium chloride
(2-Chloroethyl)(3-hydroxypropyl)ammonium chloride
All cosmetic products
0 %
16
(2-Ethylhexanoato-O)(isodecanoato-O)nickel(2-Ethylhexanoato-O)(isodecanoato-O)nickel
All cosmetic products
0 %
17
(2-Ethylhexanoato-O)(isononanoato-O)nickel(2-Ethylhexanoato-O)(isononanoato-O)nickel
All cosmetic products
0 %
18
(2-Ethylhexanoato-O)(neodecanoato-O)nickel(2-Ethylhexanoato-O)(neodecanoato-O)nickel
All cosmetic products
0 %
19
(2-Isopropylpent4-enoyl)urea(2-Isopropylpent4-enoyl)urea
All cosmetic products
0 %
20
(29H,31H-Phthalocyaninato(2-)-N29,N30,N31,N32)copper
(29H,31H-Phthalocyaninato(2-)-N29,N30,N31,N32)copper
Hair dye products
0 %
21
(2RS,3RS)-3-(2-Chlorophenyl)-2-(4-fluorophenyl)-[1H-(1,2,4-triazol-1-yl)methyl]oxirane
(2RS,3RS)-3-(2-Chlorophenyl)-2-(4-fluorophenyl)-[1H-(1,2,4-triazol-1-yl)methyl]oxirane
All cosmetic products
0 %
22
(3-Chloro-2-hydroxypropyl) trimethylammonium chloride
(3-Chloro-2-hydroxypropyl) trimethylammonium chloride
All cosmetic products
0 %
23
(3-Chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone
(3-Chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone
All cosmetic products
0 %
24
(3S,5aR,9bS)-3,3a,4,5,5a,9b-hexahydro-3,5a,9-trimethylnaphto [1,2-b] furan-2,8-dione
(3S,5aR,9bS)-3,3a,4,5,5a,9b-hexahydro-3,5a,9-trimethylnaphto [1,2-b] furan-2,8-dione
All cosmetic products
0 %
25
(4-Ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane
(4-Ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane
All cosmetic products
0 %
26
(4-Hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride
(4-Hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride
All cosmetic products
0 %
27
(4-Phenylbutyl)phosphinic acid(4-Phenylbutyl)phosphinic acid
All cosmetic products
0 %
28
(5-Chloro-2-methoxy-4-methyl-3-pyridyl)(4,5,6-trimethoxy-o-tolyl)methanone
(5-Chloro-2-methoxy-4-methyl-3-pyridyl)(4,5,6-trimethoxy-o-tolyl)methanone
All cosmetic products
0 %
Applies from 17 December 2022
29
(6-(4-Hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazine-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate
(6-(4-Hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazine-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate
All cosmetic products
0 %
30
(6R-trans)-1-((7-Ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide
(6R-trans)-1-((7-Ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide
All cosmetic products
0 %
31
(8-[(4-Amino-2-nitrophenyl)azo]-7-hydroxy-2-naphthyl) trimethylammonium
(8-[(4-Amino-2-nitrophenyl)azo]-7-hydroxy-2-naphthyl) trimethylammonium
Hair dye products
0 %
When used in hair dye products.Not permitted except for Basic Red 118 as impurity in Basic Brown 17
32
(8-[(4-Amino-2-nitrophenyl)azo]-7-hydroxy-2-naphthyl) trimethylammonium chloride
(8-[(4-Amino-2-nitrophenyl)azo]-7-hydroxy-2-naphthyl) trimethylammonium chloride
Hair dye products
0 %
When used in hair dye products.Not permitted except for Basic Red 118 as impurity in Basic Brown 17
33
(E)-2'-[2-(4-cyanophenyl)-1-(α,α,α-trifluoro-m-tolyl)ethylidene]-[4-(trifluoromethoxy)phenyl] carbanilohydrazide
(E)-2'-[2-(4-cyanophenyl)-1-(α,α,α-trifluoro-m-tolyl)ethylidene]-[4-(trifluoromethoxy)phenyl] carbanilohydrazide
All cosmetic products
0 %
Applies from 1 October 2021
34
(E)-3-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
(E)-3-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
All cosmetic products
0 %
35
(Epoxyethyl)benzene(Epoxyethyl)benzene
All cosmetic products
0 %
36
(EZ)-2'-[2-(4-Cyanophenyl)-1-(α,α,α-trifluoro-m-tolyl)ethylidene]-[4-(trifluoromethoxy)phenyl]carbanilohydrazide [E-isomer ≥ 90 %, Z-isomer ≤ 10 % relative content];Metaflumizone (ISO)
Metaflumizone (ISO)(EZ)-2'-[2-(4-Cyanophenyl)-1-(α,α,α-trifluoro-m-tolyl)ethylidene]-[4-(trifluoromethoxy)phenyl]carbanilohydrazide [E-isomer ≥ 90 %, Z-isomer ≤ 10 % relative content]
All cosmetic products
0 %
Applies from 1 October 2021
37
(Isodecanoato-O)(isononanoato-O)nickel(Isodecanoato-O)(isononanoato-O)nickel
All cosmetic products
0 %
38
(Isodecanoato-O)(isooctanoato-O)nickel(Isodecanoato-O)(isooctanoato-O)nickel
All cosmetic products
0 %
39
(Isononanoato-O)(isooctanoato-O)nickel(Isononanoato-O)(isooctanoato-O)nickel
All cosmetic products
0 %
40
(Isononanoato-O)(neodecanoato-O)nickel(Isononanoato-O)(neodecanoato-O)nickel
All cosmetic products
0 %
41
(Isooctanoato-O)(neodecanoato-O)nickel(Isooctanoato-O)(neodecanoato-O)nickel
All cosmetic products
0 %
42
(Methyl-ONN-azoxy)methyl acetate(Methyl-ONN-azoxy)methyl acetate
All cosmetic products
0 %
43
(Methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'-dipyridinium dichloride dihydrochloride
(Methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'-dipyridinium dichloride dihydrochloride
All cosmetic products
0 %
44
(R) 5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol
(R) 5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol
All cosmetic products
0 %
45
(R)-1-(2-Piperidyl)acetone(R)-1-(2-Piperidyl)acetone
All cosmetic products
0 %
46
(R)-5-Bromo-3-(1-methyl-2-pyrrolidinylmethyl)-1H-indole
(R)-5-Bromo-3-(1-methyl-2-pyrrolidinylmethyl)-1H-indole
All cosmetic products
0 %
47
(R)-α-Phenylethylammonium (-)-(1R,2S)-(1,2-epoxypropyl)phosphonate monohydrate
(R)-α-Phenylethylammonium (-)-(1R,2S)-(1,2-epoxypropyl)phosphonate monohydrate
All cosmetic products
0 %
48
(R,S)-2-Amino-3,3-dimethylbutane amide(R,S)-2-Amino-3,3-dimethylbutane amide
All cosmetic products
0 %
49
(RS)-1-{1-Ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate
(RS)-1-{1-Ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate
All cosmetic products
0 %
Applies from 17 December 2022
50
(S)-2,3-Dihydro-1H-indole-carboxylic acid(S)-2,3-Dihydro-1H-indole-carboxylic acid
All cosmetic products
0 %
51
(Z)-2-Methoxymino-2-[2-(tritylamino)thiazol-4-yl]acetic acid
(Z)-2-Methoxymino-2-[2-(tritylamino)thiazol-4-yl]acetic acid
All cosmetic products
0 %
52
(µ-((7,7'-Iminobis(4-hydroxy-3-((2-hydroxy-5-(N-methylsulphamoyl) phenyl)azo)naphthalene-2-sulphonato))(6-)))dicuprate(2-)
(µ-((7,7'-Iminobis(4-hydroxy-3-((2-hydroxy-5-(N-methylsulphamoyl) phenyl)azo)naphthalene-2-sulphonato))(6-)))dicuprate(2-)
Hair dye products
0 %
53
(µ-((7,7'-Iminobis(4-hydroxy-3-((2-hydroxy-5-(N-methylsulphamoyl) phenyl)azo)naphthalene-2-sulphonato))(6-)))dicuprate(2-), disodium salt
(µ-((7,7'-Iminobis(4-hydroxy-3-((2-hydroxy-5-(N-methylsulphamoyl) phenyl)azo)naphthalene-2-sulphonato))(6-)))dicuprate(2-), disodium salt
Hair dye products
0 %
54
1,1,2-Trichloroethane1,1,2-Trichloroethane
All cosmetic products
0 %
55
1,1,3,3,5-Pentamethyl-4,6-dinitroindane1,1,3,3,5-Pentamethyl-4,6-dinitroindane
All cosmetic products
0 %
56
1,1-Bis(dimethylaminomethyl)propyl benzoate1,1-Bis(dimethylaminomethyl)propyl benzoate
All cosmetic products
0 %
57
1,2,3,4,5,6-Hexachlorocyclohexane1,2,3,4,5,6-Hexachlorocyclohexane
All cosmetic products
0 %
58
1,2,3-Trichloropropane1,2,3-Trichloropropane
All cosmetic products
0 %
59
1,2,4-Benzenetriacetate1,2,4-Benzenetriacetate
Hair dye products
0 %
60
1,2,4-Triazole1,2,4-Triazole
All cosmetic products
0 %
61
1,2,4-Trihydroxybenzene1,2,4-Trihydroxybenzene
Hair and eyelash dye products
0 %
From 3 September 2021 hair and eyelash dye products containing those substances shall not be placed on the Union market. From 3 June 2022 hair and eyelash dye products containing those substances shall not be made available on the Union market
62
1,2,5,6,9,10-Hexabromocyclododecane1,2,5,6,9,10-Hexabromocyclododecane
All cosmetic products
0 %
63
1,2-Benzenedicarboxylic acid, di-C6-8-branched alkylesters, C7-rich
1,2-Benzenedicarboxylic acid, di-C6-8-branched alkylesters, C7-rich
All cosmetic products
0 %
64
1,2-Benzenedicarboxylic acid, di-C7-11, branched and linear alkyl esters
1,2-Benzenedicarboxylic acid, di-C7-11, branched and linear alkyl esters
All cosmetic products
0 %
65
1,2-Benzenedicarboxylic acid, dihexyl ester, branched and linear
1,2-Benzenedicarboxylic acid, dihexyl ester, branched and linear
All cosmetic products
0 %
66
1,2-Benzenedicarboxylic acid, dipentylester, branched and linear
1,2-Benzenedicarboxylic acid, dipentylester, branched and linear
All cosmetic products
0 %
67
1,2-Benzodiazepine1,2-Benzodiazepine
All cosmetic products
0 %
68
1,2-bis(2-Methoxyethoxy)ethane1,2-bis(2-Methoxyethoxy)ethane
All cosmetic products
0 %
69
1,2-Dibromo-3-chloropropane1,2-Dibromo-3-chloropropane
All cosmetic products
0 %
70
1,2-Dibromoethane1,2-Dibromoethane
All cosmetic products
0 %
71
1,2-Dichloroethane1,2-Dichloroethane
All cosmetic products
0 %
72
1,2-Dichloropropane1,2-Dichloropropane
All cosmetic products
0 %
73
1,2-Diethoxyethane1,2-Diethoxyethane
All cosmetic products
0 %
74
1,2-Dihydroxyanthraquinone1,2-Dihydroxyanthraquinone
Hair dye products
0 %
75
1,2-Epoxy-3-phenoxypropane1,2-Epoxy-3-phenoxypropane
All cosmetic products
0 %
76
1,2-Epoxy-4-epoxyethylcyclohexane1,2-Epoxy-4-epoxyethylcyclohexane
All cosmetic products
0 %
77
1,2-Epoxybutane1,2-Epoxybutane
All cosmetic products
0 %
78
1,3,5-Trihydroxybenzene1,3,5-Trihydroxybenzene
Hair dye products
0 %
79
1,3,5-Tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione
1,3,5-Tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione
All cosmetic products
0 %
80
1,3,5-tris-[(2S and 2R)-2,3-Epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione
1,3,5-tris-[(2S and 2R)-2,3-Epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione
All cosmetic products
0 %
81
1,3-Benzenediamine, 4-methyl-6-(2-phenyldiazenyl)-, hydrochloride (1:1)
1,3-Benzenediamine, 4-methyl-6-(2-phenyldiazenyl)-, hydrochloride (1:1)
Hair dye products
0 %
82
1,3-Benzenediamine, 4-methyl-6-(phenylazo)-1,3-Benzenediamine, 4-methyl-6-(phenylazo)-
Hair dye products
0 %
83
1,3-bis(Vinylsulfonylacetamido)propane1,3-bis(Vinylsulfonylacetamido)propane
All cosmetic products
0 %
84
1,3-Dichloropropan-2-ol1,3-Dichloropropan-2-ol
All cosmetic products
0 %
85
1,3-diisopropylbenzeneHydroabietyl alcohol
Fragrance ingredient
0 %
86
1,3-Dimethylpentylamine1,3-Dimethylpentylamine
All cosmetic products
0 %
87
1,3-Diphenylguanidine1,3-Diphenylguanidine
All cosmetic products
0 %
88
1,3-Isobenzofurandione, reaction products with methylqui-noline and quinoline
1,3-Isobenzofurandione, reaction products with methylqui-noline and quinoline
Hair dye products
0 %
89
1,3-Propanesultone1,3-Propanesultone
All cosmetic products
0 %
90
1,4,5,8-Tetraaminoanthraquinone1,4,5,8-Tetraaminoanthraquinone
All cosmetic products
0 %
91
1,4-bis(p-Tolylamino)anthraquinone1,4-bis(p-Tolylamino)anthraquinone
Hair dye products
0 %
92
1,4-Diamino-2-methoxy-9,10-anthracenedione1,4-Diamino-2-methoxy-9,10-anthracenedione
Hair dye products
0 %
93
1,4-Dichlorobenzene1,4-Dichlorobenzene
All cosmetic products
0 %
94
1,4-Dichlorobut-2-ene1,4-Dichlorobut-2-ene
All cosmetic products
0 %
95
1,4-Dihydroxy-5,8-bis[(2-hydroxyethyl)amino]anthraquinone
1,4-Dihydroxy-5,8-bis[(2-hydroxyethyl)amino]anthraquinone
Hair dye products
0 %
96
1,4-Dihydroxybenzene1,4-Dihydroxybenzene
All cosmetic products
0 %
Not permitted except for entry 14 in Annex III
97
1,7-Naphthalenediol1,7-Naphthalenediol
Hair dye products
0 %
98
1-((3-Aminopropyl)amino)anthraquinone, monohydrochloride
1-((3-Aminopropyl)amino)anthraquinone, monohydrochloride
All cosmetic products
0 %
99
1-((4-Phenylazo)phenylazo)-2-naphthol1-((4-Phenylazo)phenylazo)-2-naphthol
Hair dye products
0 %
100
1-(1-Naphthylmethyl)quinolinium chloride1-(1-Naphthylmethyl)quinolinium chloride
All cosmetic products
0 %