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Cosmetic, architectual and playstyle tips are not part of this list.

A collection of stuff that's easy to miss even with a lot of hours. Not targeted at beginners.
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CategoryNoTips, Tricks & FactsNotes
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Must knows1The search bar can be used as a calculator
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2When equipped, the hover pack always consumes 100 MW, even while inactive
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3Press 'e' to quick switch between buildables of the same type
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4Select blueprint mode while building to snap to other blueprints. Dismantle whole blueprints with blueprint mode. (Change mode with "r")
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5Pipes and hypertubes have different placement modes (Change mode with "r")
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6Some buildables like foundations have "zoop" and "vertical" build modes (Change mode with "r")
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7Slide jumping is faster than regular sprinting
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8Feathering the jetpack boost can get you farther and higher
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Advice9Get rid of poison pillars by exploding them
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10Use Satisfactory Tools to plan builds and resources
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11Use Satisfactory calculator to find nodes and collectibles
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12Use Satisfactory calculator to recover bugged out crates
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13If not handled carefully, recycled fluids may back up and clock your production line if fed back into the production line inputs. V.I.P. Junctions can fix this easily, follow the plumbing guide for more info (Guide correction: with recent patches you CAN actually throughput 600 m^3/min). Alternatively, the mergeless approach will spare you from any headaches
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14While placing pumps, they might snap to a blue hologram ring on the pipe representing the max headlift of the previous pump. This can cause flow issues, rather place the pumps slightly below the blue ring.
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15Copy and paste settings of signs/buildings without opening the menu, just hover over them
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16Trainstations stop outputting resources when a train docks. Use an intermediate (fluid) storage to keep the resource supply going.
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17You usually don't need screws or stators in your inventory
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Nice to know18While choosing a recipe in the M.A.M., click escape to cancel and retry [Bug]
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19You can calculate production target rates in production buildings and codex recipies
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20The angle of the jump pad can be adjusted while building
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21Save and load preset colors in the customizer
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22Right click customizer swatches to select them as standards for certain buildables
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23Ground vehicles can be fueled with all kinds of fuel types: Batteries, packaged oil and even plutonium fuel rods
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24Trains always take the shortest path, you can't make a train use another track if its path is occupied
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25You can tame lizards doggos, it'll bring you cool stuff - (Video)
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26Get huge amounts of items from A to B by mass dismantling containers with the last item selected being at your preferred destination. A crate with all items will spawn there.
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27You can ride and pet the Giant Flying Manta
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28Conveyor lifts can reach higher if they snap to a floor hole
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29Save games and blueprints are located at C:\Users\%username%\AppData\Local\FactoryGame\Saved\SaveGames
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30You can climb vine ladders
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31You can snap power poles to existing power lines
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32Enemies react to noises. You can sneak up to them if you are quiet
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33Cut only one plant with the chainsaw by having a full inventory [Pre 1.0]
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34Clapping can turn your lightings on/off
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35Conveyor lifts have a "reversed" build mode to change input and output sides when placing them freely (Change mode with "r")
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36Metal and painted beams have freefrorm and diagonal build modes (Change mode with "r")
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37Using freeform beams allows for dangerous but fast terrain climbing in the early-midgame
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38Options > Gameplay > "Automatic Clearance Seperation" always puts buildables out of the clearance of existing buildings. It makes aligning buildings easy without holding "ctrl"
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39The M.A.M. research will continue even after dismantling the building, and can be accessed from any other M.A.M. placed
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40In audio settings, expand "Factory Volume" to change the volume of a specific production building type
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41Trains slow down if the reservation block (before the path signal) is not long enough(new)
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42To add notes quickly, open the build menu ("q"), then hover and click over the shadow to the right(new)
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43Sinking the "Employee of the Planet" Cup unlocks the Golden Factory Card in the Awesome Shop
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44Sinking a coupon unlocks the Cybertruck in the Awesome Shop
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Keybinds45Tap spacebar to autocraft in the crafting bench
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46Select a buildable by pressing middle mouse button on an existing building
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47Select a blueprint by going into the "blueprint" delete mode and pressing middle mouse button on the object
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48"h" to lock a hologram and nudge it with the arrow keys
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49Hold "ctrl" while nudging to nudge in smaller increments
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50Hold "ctrl" to build foundations on the world grid (1m foundations won't align vertically!)
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51Hold 'ctrl' while placing buildings to align with other buildings
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52Replace walls and splitters by holding "ctrl" + left click
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53Hold "ctrl" to place signs down flat on foundation floors or ceilings
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54To rotate foundations at the smallest possible angle (5°), hold "ctrl" while building it on top of another foundation(new)
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55Hold right click on a stack to split with specified amounts
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56Hold shift for single stack transfers, and "ctrl" for an all stack transfer
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57Bind a key for "dismantle filter", it allows you to mass dismantle and colour only specified buildables
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58In the menu of factory buildings, you can transfer the first item of the "relevant items" section from your inventory into the building by pressing "1", the second with "2" and so on. Works with power shards and input materials. Same thing applies when equipping equipment from the inventory(new)
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59You have ten hotbars, navigate them with "alt" + mouse wheel
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60Ping and get distance of location with "alt" + left click
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61Add a stamp by pressing "alt" + right click
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