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Objective:Create a functioning microdrive system for Thomas-style electrodes that ferrets tolerate and produces recordings in an awake ferretMicrodrive parts tracker:
https://docs.google.com/spreadsheets/d/1g5M78LfF-OHI-2ouoXBg5QDyzfyszV80JRu4H8eE_kE/edit#gid=0
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Key results:1. Alex and Gianna learn to build the current prototypeSwadlow notes
https://drive.google.com/drive/u/1/folders/1PnQJUnsNmhrRYxAWm-WLktBulVLCYl_F
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2. The prototype is implanted in a ferret that has a headpost and the ferret is recorded
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3. The design is revised at least one time after lessons learned in the first animal
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What is necessary to accomplish these goals?
When?Who?ProgressNotes
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Alex and Gianna need to learn to pull and grind the Thomas-style electrodes
Week of Sep 26, Oct 3
Alex, Gianna, LisandroAlex and Gianna trained (need practice)Have gone thourgh the pulling process and grinding process together and on their own.
Waiting for more fibers to come in, could use more practice.
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Alex and Gianna to be trained and put on the ferret protocolASAPAlex, Gianna, Avi
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Alex and Gianna need to receive 3-d printing training and practice printing the designWeek of Oct 3Alex, Gianna, LisandroGianna, Rico and Alex trainined on 3D printer. Need to practice printing
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Alex and Gianna need to learn to assemble the prototype and connect the EIB boardWeek of Oct 10Alex, Gianna, LisandroAlex and Gianna have learned the steps; need to go through all of them on their ownNeed more practice shaping screws. Need to practice all the other assembly steps as well.
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redesign exit of microdriveHave current metal based Jadhav design, will base new design on that
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first cast and attempt at new shuttle/drive for discussionby Dec 8
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Rico builds new EIB board
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We need to implant a prototype on a ferret
Week of Oct 17 or later
Lisandro, Rico, Alex, and GiannaHaving difficulty connecting prototype to EIB. A few more electrodes broke in the processs (2-3 electrodes left out of 8). Considering making a new drive and using gold pins for this implant. Can brainstorm some otherways of connecting to EIB while building new drive.
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We need to evaluate the prototype in a recording setting
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Re-design (if necessary) the microdrives to better achieve our goals in the ferret
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Discussed alternatives:
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Focus on carbon fiber microdrives
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Focus on the Thomas Electrode microdrives (learning how to make them and troubleshoot them)
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Learning how to make the Thomas electrodes
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Carbon fiber tip preparation
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