ABCDEFGHIJKLMNOPQRSTUVWXYZ
1
Supplementary Information for
2
3
Ancient autozygous segments subject to positive selection suggest adaptive immune responses in West African cattle
4
 Félix Goyache1, Iván Fernández, Amadou Traoré, Lucía Pérez-Pardal, Nuria A. Menéndez-Arias and Isabel Álvarez
5
1To whom correspondence and requests should be addressed (e-mail: fgoyache@serida.org)
6
7
This .xlsx file includes:
8
Supplementary Table S1 Description of sampling
9
Supplementary Table S2 Description of the individuals typed.
10
Supplementary Figure S1 Plot showing cross-validation errors (CV) for each K tested using the program Admixture v1.23
11
Supplementary Table S3 List of chromosome segments under putative selection in taurine cattle
12
Supplementary Table S4 List of chromosome segments under putative selection in sanga cattle
13
Supplementary Table S5 List of chromosome segments under putative selection in zebu cattle
14
Supplementary Table S6 List of chromosome segments including unique HBD segments in taurine cattle
15
Supplementary Table S7 List of chromosome segments including unique HBD segments in sanga cattle
16
Supplementary Table S8 List of chromosome segments including unique HBD segments in zebu cattle
17
Supplementary Table S9 List of candidate genomic regions identified in West African taurine cattle
18
Supplementary Table S10 List of candidate genomic regions identified in West African sanga cattle
19
Supplementary Table S11 List of candidate genomic regions identified in West African zebu cattle
20
Supplementary Table S12 List of 1,001 candidate genes located on the taurine cattle candidate genomic regions identified .
21
Supplementary Table S13 List of 309 candidate genes located on the sanga cattle candidate genomic regions identified .
22
Supplementary Table S14 List of 66 candidate genes located on the zebu cattle candidate genomic regions identified .
23
Supplementary Table S15 Functional terms enriched clusters identified following DAVID analysis on the candidate genomic regions defined in West African taurine cattle .
24
Supplementary Table S16 Functional terms enriched clusters identified following DAVID analysis on the candidate genomic regions defined in West African sanga cattle .
25
Supplementary Table S17 Functional terms enriched clusters identified following DAVID analysis on the candidate genomic regions defined in West African zebu cattle .
26
Supplementary Table S18 Summary of the 123 candidate genes belonging to the six statistically significant Functional Clusters identified in taurine, sanga and zebu cattle.
27
Supplementary Table S19 Summary of the 35 candidate genes belonging to three non significant Annotation Clusters identified in taurine FCt52 and FCt66) and sanga cattle (FCs18).
28
Supplementary Figure S2 Circular map summarizing the relationships between candidate genes belonging to taurine 52 and 66 and sanga 18 Annotation Clusters overlapping with QTL for trypanotolerance–related traits.
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100