Conditional power assessment

	A	B	F
1	Conditional Power Assessment for Binomial Event
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3		Study Planning Parameters
4		False Postive Rate (Alpha) =	5.00%
5		False Negative Rate (Beta) =	20.00%
6		1 sided/2 sided test =	2
7		% Randomized to Arm with Higher event rate =	50.00%
8		Higher Event Arm (ARM A) Rate =	60.00%
9		Lower Event Arm (ARM B) Rate =	45.00%
10		Sample Size in Higher Event Rate Group =	171
11		Sample Size in Lower Event Rate Group =	171
12		Expected value of Final Test Statistic under alternate hypothesis =	2.802
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14		Interim Results
15		Interim Sample in ARM A =	60
16		Number of Events in ARM A =	37
17		Interim Sample in ARM B =	62
18		Number of Events in ARM B =	31
19		Interim Estimated Test Statistic =	1.307
20		B-value at Interim =	0.781
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22		Frequentist Conditional Power
23		Information Fraction at Interim =	0.358
24		Projected Expected value of Final Test Statistic given B-value at Interim on assuming null hypothesis effect =	0.781
25		Conditional Power Under Null Effect =	7.07%
26		Projected Expected value of Final Test Statistic given B-vallue at Interim on assuming current trend continues =	2.185
27		Conditional Power Under Current Trend =	61.06%
28		Projected Expected value of Final Test Statistic given B-vallue at Interim on assuming future alternate hypothesis effects =	2.581
29		Conditional Power Under Alternate =	78.08%
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31		Bayesian Predictive Power
32		Weight on Prior Hypothesized Opinion =	20.00%
33		Predictive Power =	63.21%
34		Predictive Power under a weight of 100*(1-information fraction) =	72.85%
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