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Multi-Ligand Binding Model: T, DHT, E2, E1, C (with CBG calc)
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Solved by Successive Substitution (20 iterations)
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Spreadsheet Programmed by Norman Mazer, M.D., Ph.D.
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Date:24-Jan-09
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Subj ID:
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Subj Init:YM
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Input Data:
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T_tot (ng/dL)30default 0
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DHT_tot (ng/dL)10default 0
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E2_tot (pg/mL)200default 0
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E1_tot (pg/mL)200default 0
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Cortisol (ug/dL)13default 0
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Alb_tot (g/dL)4.5default 4.3 *
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SHBG_tot (nmol/L)50default 0
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CBG (mg/dL)4default 0
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Output:
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cFT (pg/mL)4.06
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cFDHT (pg/mL)0.58
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cFE2 (pg/mL)3.68
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cFE1(pg/mL)6.90
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cFC (ng/mL)4.95
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cBT (ng/dL)9.94
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cBDHT (ng/dL)2.48
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cBE2 (pg/mL)112.67
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cBE1 (pg/mL)168.95
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cFT (%)1.35%
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cFDHT (%)0.58%
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cE2 (%)1.84%
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Vermeulen Model (JCEM 1999;84:3666-3672):
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cFT (pg/mL)4.07
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* If Alb is left empty, the default value will be 4.3 g/dL
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