Cost-effectiveness estimate based on GiveWell method
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Disease
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Group of diseases
Disease
2012 annual global spend, 2007 dollars
2012 annual global spend, 2012 dollars
Total DALY burden
Expected reduction of disease burden attributable to research
DALYs averted by research
Time delay to benefits
Discount rate
Population growth rate
Net benefit discount rate
Total spend
Discount applied to total benefits
Total benefitsCost per DALY
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HIVHIV1,064,000,0001189871200919070000.545953500500.030.01130.9818446602315335583300.4000728931607507753.251.90642945
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MalariaMalaria542500000606677750551110000.527555500500.030.01130.9818446602160779655960.400072893136428519944.13565426
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TBTB502100000561498430436500000.521825000500.030.01130.9818446602148806387570.4000728931288527679.451.57438894
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Diarrhoeal disease
Diarrhoeal diseases
106390000118975937997280000.549864000500.030.01130.981844660231530594650.4000728931659204774.54.783125952
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HelminthsTotal844000009438452052660000.52633000500.030.01130.981844660225013461680.400072893134808402.2871.86041313
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Hookworm7600000849908032460000.51623000500.030.01130.9818446602225239702.40.400072893121456147.710.49767673
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Ascariasis1900000212477013550000.5677500500.030.01130.981844660256309925.590.40007289318956586.616.286984991
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Trichuriasis8000008946406660000.5333000500.030.01130.981844660223709442.350.40007289314402277.9945.385721298
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Parasitic and vector diseases
Lymphatic filariasis
134000001498522028390000.51419500500.030.01130.9818446602397133159.40.400072893118765866.7121.16252692
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Schistosomiasis
262000002929946040260000.52013000500.030.01130.9818446602776484237.10.400072893126611968.7829.17800797
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Onchocerciasis11400000127486205980000.5299000500.030.01130.9818446602337859553.50.40007289313952796.15785.47355849
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Dengue9360000010467288014450000.5722500500.030.01130.981844660227740047550.40007289319551489.042290.4264187
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Leishmaniasis387300004331175933740000.51687000500.030.01130.981844660211478333780.400072893122302231.1651.46719939
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Chagas disease
31690000354389275280000.5264000500.030.01130.9818446602939190285.20.40007289313490094.266269.1016957
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Trypanosomiasis
368000004115344012640000.5632000500.030.01130.981844660210906343480.40007289318355074.152130.5355678
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MeningitisMeningititis99200000110935360301820000.515091000500.030.01130.981844660229399708520.4000728931199503835.514.73641268
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Salmonella
Non-typhoidal Salmonella enterica (NTS)
81000009058230#VALUE!0.5#VALUE!500.030.01130.9818446602240058103.80.4000728931#VALUE!#VALUE!
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Typhoid and paratyphoid fever
3620000040482460#VALUE!0.5#VALUE!500.030.01130.981844660210728522660.4000728931#VALUE!#VALUE!
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Multiple salmonella infections
84000009393720#VALUE!0.5#VALUE!500.030.01130.9818446602248949144.70.4000728931#VALUE!#VALUE!
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LeprosyLeprosy13100000146497302570000.5128500500.030.01130.9818446602388242118.50.40007289311698776.944228.5421402
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Rheumatic Fever
Rheumatic Fever
9000001006470119540000.55977000500.030.01130.981844660226673122.650.400072893179016262.980.3375649726
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TrachomaTrachoma870000097292102990000.5149500500.030.01130.9818446602257840185.60.40007289311976398.079130.4596419
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Buruli UlcerBuruli Ulcer61000006821630#VALUE!0.5#VALUE!500.030.01130.9818446602180784497.90.4000728931#VALUE!#VALUE!
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Total2,742,210,000.0030666134433576950000.5178847500500.030.01130.9818446602812703373950.4000728931236437361434.37288291
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Source
http://www.policycures.org/downloads/04_GF_report13_web_Findings%E2%80%93Funding%20by%20Disease.pdf
Calculation
http://www.who.int/healthinfo/global_burden_disease/estimates/en/index2.html
AssumptionCalculationAssumptionAssumption
http://www.worldometers.info/world-population/#growthrate
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