Supplement 4 .xls

	A	B	C	D	E	F
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2	Upstream Regulator	Expr p-value	Molecule Type	p-value of overlap	Target Molecules in Dataset	Mechanistic Network
3	MRTFA		transcription regulator	0.00207	FIBIN,GAS2,ID1,MAP2
4	AREG		growth factor	0.00324	CENPF,DESI2,ELF3,RRM2,TXNRD1
5	NOTCH3		transcription regulator	0.00377	CFLAR,HES5,ID1
6	POU5F1		transcription regulator	0.00406	APAF1,BFAR,BIRC6,CASP14,NCAM1,RIPK2,TP73
7	HNF1A		transcription regulator	0.00493	CREBL2,ELF3,HNMT,NR5A2,UQCRC2,UROD
8	CBL		transcription regulator	0.00511	CFLAR,RUNX2
9	miR-17-5p (and other miRNAs w/seed AAAGUGC)		mature microRNA	0.00707	RUNX2,TP73
10	ZEB1		transcription regulator	0.0118	PTPRZ1,TP73
11	SENP8		peptidase	0.019	TP73
12	Laminin (complex)		complex	0.019	RUNX2
13	DHODH		enzyme	0.019	CFLAR
14	ERAP1		peptidase	0.019	HLA-G
15	HSP90AA1		enzyme	0.019	CFLAR
16	BMPR1B		kinase	0.019	ID1
17	CASP2		peptidase	0.019	NCAM1
18	RCHY1		enzyme	0.019	TP73
19	CASP9		peptidase	0.019	NCAM1
20	SDC1		enzyme	0.019	CFLAR
21	AP2B1		transporter	0.019	PTGDS
22	MRTFB		transcription regulator	0.0228	FIBIN,GAS2,ID1,MAP2
23	JUNB		transcription regulator	0.032	CFLAR,ITGB4
24	NFAT (complex)		complex	0.0376	CFLAR
25	Ppp2c		group	0.0376	ID1
26	SOX5		transcription regulator	0.0376	SPAG6
27	PURA		transcription regulator	0.0376	AR
28	CBR3-AS1		other	0.0376	ERBB2
29	NEUROD1		transcription regulator	0.0376	NCAM1
30	mir-26		microRNA	0.0376	FGF9
31	LPAR1		G-protein coupled receptor	0.0376	SPHK1
32	CDKN2D		transcription regulator	0.0376	GATA1
33	YBX3		transcription regulator	0.0376	ERBB2
34	LIF		cytokine	0.0376	HLA-G
35	CASP8AP2		transcription regulator	0.0376	CFLAR
36	BAG1		other	0.0376	TP73
37	HSP90AB1		enzyme	0.0376	CFLAR
38	TP53COR1		other	0.0496	APAF1,CFLAR
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