Phase 2 Status review
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Date of review22-Apr-2018Last review11/13/17
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AreaProject elementProgrammatic responsibilityLeaderTeamMilestone (with link to Trello card)Planned dateHealthCommentsUpdated
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1 Information TechnologyProject database, Website and TrelloMargoBethJose-Miguel, Albeb, Gizelle B.isolate and voucher locations updated3/30/18Y voucher locations to be done by Gizelle B., update US strains from JMR, UP, physical locations need audit
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1 Information TechnologyMeta/genomics metabolite miningEricMarvinLin/Dan/Ayipathway-based prioritization3/30/18Gcollaborate with Amaro
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2 Collection and microbiologyspecimen archivingGaryGizelleMalem/JessacompletedGLabeling? Touch base with Giz B, check on San Carlos samples
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2 Collection and microbiologyBacterial isolationMargoJose-Miguel/MarvinMarvin/Jose MIguelFeb collection isolations4/10/18Gx
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2 Collection and microbiologyBacterial characterizationMargoMarvinJose-Migueladd new seqs to shared folder and link to database, existing collection2/28/2018Gadd 16S sequences to the database
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2 Collection and microbiologyStrain ArchivingGiselleJose MiguelMarvinnew strains archived including database4/17/2018G
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2 Collection and microbiologyField collectionsGiselleMarvinJose MiguelPlan next (last?) collection trip5/31/18G
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3 AssaysConstellation PharmacologyTotoRussJoshuaset up cell culture facility12/1/17G
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3 AssaysDRG assaysGiselleJortanZildjiancomplete current extracts1/15/18Greview hits with Russ and Toto
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3 AssaysAntimicrobial AssaysGiselleJose MiguelNoel/Albeb/Arthur/Mariellecomplete assay of shipworm isolates2/15/18Ggastropod isolates further alongx
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3 AssaysCytotoxicity AssaysGiselleJortan/AlbebMyrashipworm symbiont extracts complete2/15/18Gphase 2 gastropods donex
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3 AssaysSecondary AssaysEricEricRuss/Joshuaevaluate Joshua's hit?Yalso antimicrobial secondary screening
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3 AssaysHIV AssaysLouJortanJortan/MyraScreen Phase 2 extracts1/10/18Gneed Jortan's input
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4 ChemistryChemical LibraryGiselleBaileyNoel, Lilibeth/BethdoneGneed Noel's input
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4 ChemistryGrow-out and extractionGiselleNoelMJ, Jose Miguel, Marvin/othersimprove growth protocol for shipworm isolates??Yget seawater and optimize
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4 ChemistryEarly dereplication and prioritizationGiselleBailey/LinNoel, Lilibeth/Eric/Joshuapurchase MarineLit subscription12/1/2018GSubscription for MarinLit?
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4 ChemistryScale-up and identificationGiselleLilibeth/LinNoel ,Joshua/MarvinOKGGriseorhodins on hold due to IP
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4 ChemistryMedicinal chemistryEric/AaronLinbioassay of synthetic nobilamides4/30/18G
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4 ChemistrybiosynthesisEricJoshuaJose Miguel, Baileyin frame deletion of butuanimide genes5/15/18
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5 Basic Research: BiodiversityBiodiversityGaryGaryGizelle B.submit Batanes ms4/30/2018Gtwo ms.
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5 Basic Research: BiodiversityBiodiversityGaryReubenWood-dwelling Kuphus3/30/18Gbiol bull
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5 Basic Research: BiodiversityBiodiversityDanReubenshipworm phylogeny paper submit5/15/18
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6 Basic Research: Symbiosischemical charactisation of symbiosesEric/MargoBaileyBailey/ReubenMetabolomics/MALDI on B.son holdYx
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6 Basic Research: SymbiosisShipworm symbiontsMargo/DanMarvin/HiroakiMarvin/HiroakiKp strain species description submit11/30/17G
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6 Basic Research: SymbiosisGastropod symbiontsEric/MargoJoshuaGtry to cultivate
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7 Administration: GeneralIndustrial collaborationsMargoDavid HadleyExplore Eisai collaborationon holdY
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7 Administration: GeneralLegalMargoDavid Hadley
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8 Administration: PhilippinesAgreements and permitsGiselleJessarenewal of GP?GExport Permit/usfws importation
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