| A | B | C | D | E | F | G | H | I | J | |
|---|---|---|---|---|---|---|---|---|---|---|
1 | Date of review | 22-Apr-2018 | Last review | 11/13/17 | ||||||
2 | Area | Project element | Programmatic responsibility | Leader | Team | Milestone (with link to Trello card) | Planned date | Health | Comments | Updated |
3 | 1 Information Technology | Project database, Website and Trello | Margo | Beth | Jose-Miguel, Albeb, Gizelle B. | isolate and voucher locations updated | 3/30/18 | Y | voucher locations to be done by Gizelle B., update US strains from JMR, UP, physical locations need audit | |
4 | 1 Information Technology | Meta/genomics metabolite mining | Eric | Marvin | Lin/Dan/Ayi | pathway-based prioritization | 3/30/18 | G | collaborate with Amaro | |
5 | 2 Collection and microbiology | specimen archiving | Gary | Gizelle | Malem/Jessa | completed | G | Labeling? Touch base with Giz B, check on San Carlos samples | ||
6 | 2 Collection and microbiology | Bacterial isolation | Margo | Jose-Miguel/Marvin | Marvin/Jose MIguel | Feb collection isolations | 4/10/18 | G | x | |
7 | 2 Collection and microbiology | Bacterial characterization | Margo | Marvin | Jose-Miguel | add new seqs to shared folder and link to database, existing collection | 2/28/2018 | G | add 16S sequences to the database | |
8 | 2 Collection and microbiology | Strain Archiving | Giselle | Jose Miguel | Marvin | new strains archived including database | 4/17/2018 | G | ||
9 | 2 Collection and microbiology | Field collections | Giselle | Marvin | Jose Miguel | Plan next (last?) collection trip | 5/31/18 | G | ||
10 | 3 Assays | Constellation Pharmacology | Toto | Russ | Joshua | set up cell culture facility | 12/1/17 | G | ||
11 | 3 Assays | DRG assays | Giselle | Jortan | Zildjian | complete current extracts | 1/15/18 | G | review hits with Russ and Toto | |
12 | 3 Assays | Antimicrobial Assays | Giselle | Jose Miguel | Noel/Albeb/Arthur/Marielle | complete assay of shipworm isolates | 2/15/18 | G | gastropod isolates further along | x |
13 | 3 Assays | Cytotoxicity Assays | Giselle | Jortan/Albeb | Myra | shipworm symbiont extracts complete | 2/15/18 | G | phase 2 gastropods done | x |
14 | 3 Assays | Secondary Assays | Eric | Eric | Russ/Joshua | evaluate Joshua's hit | ? | Y | also antimicrobial secondary screening | |
15 | 3 Assays | HIV Assays | Lou | Jortan | Jortan/Myra | Screen Phase 2 extracts | 1/10/18 | G | need Jortan's input | |
16 | 4 Chemistry | Chemical Library | Giselle | Bailey | Noel, Lilibeth/Beth | done | G | need Noel's input | ||
17 | 4 Chemistry | Grow-out and extraction | Giselle | Noel | MJ, Jose Miguel, Marvin/others | improve growth protocol for shipworm isolates | ?? | Y | get seawater and optimize | |
18 | 4 Chemistry | Early dereplication and prioritization | Giselle | Bailey/Lin | Noel, Lilibeth/Eric/Joshua | purchase MarineLit subscription | 12/1/2018 | G | Subscription for MarinLit? | |
19 | 4 Chemistry | Scale-up and identification | Giselle | Lilibeth/Lin | Noel ,Joshua/Marvin | OK | G | Griseorhodins on hold due to IP | ||
20 | 4 Chemistry | Medicinal chemistry | Eric/Aaron | Lin | bioassay of synthetic nobilamides | 4/30/18 | G | |||
21 | 4 Chemistry | biosynthesis | Eric | Joshua | Jose Miguel, Bailey | in frame deletion of butuanimide genes | 5/15/18 | |||
22 | 5 Basic Research: Biodiversity | Biodiversity | Gary | Gary | Gizelle B. | submit Batanes ms | 4/30/2018 | G | two ms. | |
23 | 5 Basic Research: Biodiversity | Biodiversity | Gary | Reuben | Wood-dwelling Kuphus | 3/30/18 | G | biol bull | ||
24 | 5 Basic Research: Biodiversity | Biodiversity | Dan | Reuben | shipworm phylogeny paper submit | 5/15/18 | ||||
25 | 6 Basic Research: Symbiosis | chemical charactisation of symbioses | Eric/Margo | Bailey | Bailey/Reuben | Metabolomics/MALDI on B.s | on hold | Y | x | |
26 | 6 Basic Research: Symbiosis | Shipworm symbionts | Margo/Dan | Marvin/Hiroaki | Marvin/Hiroaki | Kp strain species description submit | 11/30/17 | G | ||
27 | 6 Basic Research: Symbiosis | Gastropod symbionts | Eric/Margo | Joshua | G | try to cultivate | ||||
28 | 7 Administration: General | Industrial collaborations | Margo | David Hadley | Explore Eisai collaboration | on hold | Y | |||
29 | 7 Administration: General | Legal | Margo | David Hadley | ||||||
30 | 8 Administration: Philippines | Agreements and permits | Giselle | Jessa | renewal of GP | ? | G | Export Permit/usfws importation | ||
31 |