ABCDEFGH
1
Location of the epidemic/pandemicStart yearEnd yearDeathsGlobal population at the start yearDiseaseReferencesNotes
2
China, Kwangsi150015005.00E+034.63E+08UnknownMcNeill, 1998
3
China, Shansi150415045.00E+034.63E+08UnknownMcNeill, 1998
4
China, Hunan, Hupeh, Kwangtun, Kwangsi, yunnan, Fukien150615065.00E+034.63E+08UnknownMcNeill, 1998
5
Hispaniola150715413.00E+054.63E+08SmallpoxKohn, 1999
6
Pandemic, Influenza151015105.00E+034.63E+08InfluenzaMorens et al., 2010
7
China, Chekiang151115115.00E+034.63E+08UnknownMcNeill, 1998
8
China, Yunnan151415145.00E+034.63E+08UnknownMcNeill, 1998
9
China, Hupeh151615165.00E+034.63E+08UnknownMcNeill, 1998
10
China, Fukien151715175.00E+034.63E+08UnknownMcNeill, 1998
11
China, Hopei, Shantung, Chekiang151915195.00E+034.63E+08UnknownMcNeill, 1998
12
Ireland151915255.00E+034.63E+08PlagueKohn, 1999
13
Mexico151915206.50E+064.63E+08SmallpoxAcuna-Soto et al., 2002
14
European diseases in the Americas152016351.03E+074.75E+08Smallpox, etc.Kohn, 1999; Lovell, 1992
15
China, Shensi152215225.00E+034.77E+08UnknownMcNeill, 1998
16
China, Shantung152515254.10E+034.79E+08UnknownMcNeill, 1998
17
French army in Italy152815282.10E+044.82E+08TyphusSocolovschi and Raoult, 2009
18
China, Shansi, Hupeh, Szechwan, Kweichow152815295.00E+034.82E+08UnknownMcNeill, 1998
19
England, Germany, northern Europe152915295.00E+034.83E+08Sweating SicknessKohn, 1999
20
Edimburgh153015305.00E+034.84E+08PlagueKohn, 1999
21
China, Shensi, Hupeh, Chekiang, Hunan, Fukien153215355.00E+034.85E+08UnknownMcNeill, 1998
22
Ireland153515365.00E+034.88E+08UnknownKohn, 1999
23
China, Kwangsi153815385.00E+034.91E+08UnknownMcNeill, 1998
24
Ottoman war154215423.00E+044.94E+08TyphusSocolovschi and Raoult, 2009
25
China, Shansi, Honan, Fukien154315455.00E+034.95E+08UnknownMcNeill, 1998
26
Americas154515481.00E+074.97E+08CocolitzliAcuna-Soto et al., 2000; 2002; Vagene et al. 2018
27
India, Goa154515458.00E+034.97E+08SmallpoxFenner et al., 1988
28
England155115515.00E+035.02E+08Sweating SicknessKohn, 1999
29
Siege of Metz155215521.00E+045.03E+08TyphusConlon, 2009
30
China, Hopei155415545.00E+035.05E+08UnknownMcNeill, 1998
31
Brazil155515635.00E+035.06E+08SmallpoxKohn, 1999; Cliff, 2004
32
China, Fukien155615565.00E+035.07E+08UnknownMcNeill, 1998
33
Typhus outbreak in England155715593.00E+055.08E+08TyphusSocolovschi and Raoult, 2009Estimated from 10% of English population in the period
34
China, Kweichow155815585.00E+035.09E+08UnknownMcNeill, 1998
35
Austrian army in Hungary156015603.00E+045.10E+08TyphusConlon, 2009
36
China, Hupeh, Fukien, Kiangsi156115635.00E+035.11E+08UnknownMcNeill, 1998Sources states that 7/10 of population died in Fukien
37
London156315632.00E+045.13E+08PlagueKohn, 1999
38
Lyon156415645.00E+035.14E+08PlagueKohn, 1999
39
China, Hope and Chekiang156515655.00E+035.15E+08UnknownMcNeill, 1998
40
Hungary - Maximilian II army156615665.00E+035.16E+08TyphusKohn, 1999
41
China, Shansi157115715.00E+035.20E+08UnknownMcNeill, 1998
42
China, Hupeh157315735.00E+035.22E+08UnknownMcNeill, 1998
43
Ireland, Venice, London157515775.80E+045.25E+08Plaguehttps://en.wikipedia.org/wiki/Second_plague_pandemicSum of Venice, Ireland and London epidemics
44
Americas157615782.00E+065.25E+08CocolitzliAcuna-Soto et al, 2000
45
Paris157615765.00E+035.25E+08DiphtheriaKohn, 1999
46
Oxford157715775.00E+035.26E+08TyphusKohn, 1999
47
Paris157815785.00E+035.26E+08Whooping CoughKohn, 1999
48
China, Shansi, Hopei, Szechwan, Shantung157915825.00E+035.27E+08UnknownMcNeill, 1998
49
Italy158015805.00E+035.28E+08InfluenzaKohn, 1999
50
Venezuela158015802.00E+045.28E+08SmallpoxKohn, 1999
51
Spain and Italy158316185.00E+035.31E+08DiphtheriaKohn, 1999Merged Spanish (1583-1618) and Italian (1618) outbreaks
52
China, Hupeh, Shansi158415855.00E+035.33E+08UnknownMcNeill 1998
53
Edimburgh158515851.00E+035.33E+08PlagueKohn, 1999
54
Peru158515855.00E+035.33E+08SmallpoxKohn, 1999
55
Exeter158615865.00E+035.34E+08TyphusKohn, 1999
56
China, Shansi, Kiangsi, Shantung, Shensi, Chekiang, Honan158715885.00E+035.34E+08UnknownMcNeill, 1998
57
Madrid158715875.00E+035.34E+08SmallpoxCliff, 2004
58
China, Hupeh, Hunan, Kwangtung159015905.00E+035.37E+08UnknownMcNeill, 1998
59
Mexico highlands159016002.00E+065.37E+08TyphusHarden, 1993; Cliff, 2004More than 2000k deaths according to Harden, 1993
60
Philippines159115915.00E+035.38E+08SmallpoxKohn, 1999
61
Western New York159215965.00E+035.39E+08MeaslesKohn, 1999
62
London and Malta159215932.30E+045.39E+08PlagueCreighton (1891)Estimate is 17 k deaths according to Kohn, 1999
63
China, Yunnan159415945.00E+035.41E+08UnknownMcNeill, 1998
64
Spain and Scotland and Prussia, London and Ireland159616055.70E+055.42E+08PlagueKohn, 1999Includes Edimburgh 1597, which has no number estimate, Scoltand 1600-1608, Prussia 1602 with 20k deaths, London 1603 with 35k deaths, and Ireland with Unknown number of deaths
65
China, Yunnan, Szechwan159715985.00E+035.43E+08UnknownMcNeill, 1998
66
China, Shansi, Kweichow160116015.00E+035.45E+08UnknownMcNeill, 1998
67
China, Chekiang160316035.00E+035.44E+08UnknownMcNeill, 1998
68
China, Chekiang160616065.00E+035.43E+08UnknownMcNeill, 1998
69
China, Yunnan, Fukien, Shansi, Shensi, Chekian160816135.00E+035.42E+08UnknownMcNeill, 1998
70
Basel161016115.00E+035.41E+08PlagueKohn, 1999
71
China, Fukien, Shansi, Hunan, Kweichow, Yunnan161716185.00E+035.37E+08UnknownMcNeill, 1998Corpses lying side by side in Shansi according to McNeill 1998
72
Massachusetts161716195.00E+035.37E+08SmallpoxKohn, 1999
73
Thirty years war including Germany and Lyon and Limoges Typhus Epidemic161816496.20E+065.37E+08TyphusSocolovschi and Raoult, 20096,200k deaths are estimated from 50% of the total german population
74
Algiers162016214.00E+045.36E+08PlagueHarding, 2002
75
China, Hupeh, Yunnan, Kwangsi162116245.00E+035.35E+08UnknownMcNeill, 1998
76
London162516251.00E+055.33E+08PlagueKohn, 1999
77
China, Hupeh162716275.00E+035.32E+08UnknownMcNeill, 1998
78
France and Italy162816311.28E+065.31E+08PlagueHarding, 2002
79
Central New York163016621.00E+045.30E+08SmallpoxKohn, 1999
80
Protestant-Catholic armies at Nuremburg163216321.80E+045.29E+08TyphusConlon, 2009
81
China, Shansi163316355.00E+035.29E+08UnknownMcNeill, 1998
82
Massachusetts and Connecticut163316345.00E+035.29E+08SmallpoxKohn, 1999
83
Quebec163416405.00E+035.28E+08MeaslesKohn, 1999
84
London and Spain163616373.30E+045.27E+08PlagueKohn, 1999Sum of London 1636 and Spain 1637 (20k deaths)
85
China, Hopei, Chekiang, Honan, Shantung, Shansi164016415.00E+035.25E+08UnknownMcNeill, 1998corpses lying side by side throughout
86
China, Shensi, Shansi, Kiangsu, Inner Mongolia164316445.00E+035.24E+08UnknownMcNeill, 1998
87
Oxford and Reading164316435.00E+035.24E+08TyphusKohn, 1999
88
Tiverton164416445.00E+035.23E+08TyphusKohn, 1999
89
Barbados164716475.00E+035.22E+08Yellow FeverKohn, 1999
90
Massachusetts164816495.00E+035.21E+08SmallpoxKohn, 1999
91
China, Inner Mongolia165316535.00E+035.26E+08UnknownMcNeill, 1998
92
Russia, Rome and Naples165416557.00E+055.28E+08PlagueKohn, 1999; Harding 2002; Scasciamacchia, 2012
93
Jamaica165516555.00E+035.30E+08Yellow FeverKohn, 1999
94
China, Kansu165616565.00E+035.32E+08UnknownMcNeill, 1998
95
India and Brazil, Boston (0k) and London (0k)166016691.08E+055.40E+08SmallpoxFenner et al., 1988
96
London166116651.60E+045.42E+08TyphusKohn, 1999
97
London, Germany, Austria and Switzerland166316688.75E+045.50E+08PlagueKohn, 1999
98
China, Shantung166516655.00E+035.50E+08UnknownMcNeill, 1998
99
China, Kansu, Hopei166716685.00E+035.54E+08UnknownMcNeill, 1998
100
New York166816685.00E+035.56E+08Yellow FeverKohn, 1999