NCoV-19 proteins
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Accession number
namefunctionsize (aa)blastp resultsstructures
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YP_009725297.1
nsp1leader protein180 aa29,903
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YP_009725298.1
nsp2does not say638 aaNo drugs in structures1N7U
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YP_009725299nsp3predicted phosphoesterase, papain-like proteinase, Y-domain, transmembrane domain 1 (TM1), adenosine diphosphate-ribose 1''-phosphatase (ADRP);1945 aano drugs in structure5E6J
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YP_009724389.1nsp4Contains transmembrane domain 25003VCB
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YP_009725301.1nsp53C like proteinase
306 aaThe crystal structure of COVID-19 main protease in complex with an inhibitor N36LU7_A5WJK
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nsp6transmembrane domain290 aaPhosphoaminophosphonic Acid-adenylate Ester3PLSlook at this
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YP_009725303nsp7does not say83 aa
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YP_009725304
nsp8produced by both pp1a and pp1ab198 aano drugs in structures6NUR_B. 2AHM_E
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YP_009725305YP_009724396ssRNA-binding protein113 aaGlycerol3EE7
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YP_009725306nsp10formerly known as growth-factor-like protein (GFL)139 aaGuanosine-P3-Adenosine-5',5'-Triphosphate
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YP_009725307nsp11N/A13 aaS-Adenosylmethionine3R24
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YP_009725307.1
nsp12RNA-dependent RNA polymerase932no drugs in structures6NUS. 6NUR
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YP_009725309nsp13zinc-binding domain (ZD), NTPase/helicase domain (HEL), RNA 5'-triphosphatase; produced by pp1ab only"601 aano drugs in structures6JYT
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YP_009725310nsp143' to 5' exonuclease527 aaS-adenosyl-L-homocysteine (comp. inhib. candidate) and GTP5C8S_B (Complex with nsp10)
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YP_009725311nsp15produced by pp1ab only346 aano drugs in structures2OZK. 2RHB
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YP_009725312nsp16orf1a polyprotein4405
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orf1abNA7096 aaS-Adenosyl- l-homocysteine5C86
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orf3aN/A275 aano structures
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YP_009724390.1
Ssurface glycoprotein, spike1273human receptor is ACE2 --> ACE2 inhibitors may potentially block6ACK
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Eenvelope protein75no drugs in structures
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Mmembrane glycoprotein222
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Nnucleocapsid phosphoprotein419no drugs in structures1SSK
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orf1a4405 aaAcetic Acid; (5s,8s,14r)-Ethyl 11-(3-Amino-3-Oxopropyl)-8-Benzyl-14-Hydroxy-5-Isobutyl-3,6,9,12-Tetraoxo-1-Phenyl-2-Oxa-4,7,10,11-Tetraazapentadecan-15-Oate2GTB (2A5K_A)
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